• Title/Summary/Keyword: Ethnic Difference

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Genotype and Allele Frequency of the Short Tandem Repeat F13A01 Locus by Polymerase Chain Reaction in Korean (한국인에서 중합효소반응을 이용한 short tandem repeat 유전좌위 F13A01 유전자형 및 대립유전자 빈도)

  • Young-Su Lee;Chang-Lyuk Yoon
    • Journal of Oral Medicine and Pain
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    • v.21 no.2
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    • pp.317-329
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    • 1996
  • Allelic frequency and genotype distribution of short tandem repeat(STR) F13A01 locus was analysed by polymerase chain reaction, polyacrylamide gel electrophoresis and silver staining from human genomic deoxyribonucleic acid(DNA) was extracted from 205 unrelated Korean to be applied to forensic identification and parentage testing as a database. The results were as follows : 1. 5 alleles and 11 genotypes of F13A01 locus were detected and heterozygosity value was 62.0% and the observed each alleles and allelic frequency was 3.2(0.363), 4(0.105), 5(0.063), 6(0.466), 16(0.002). 2. The allelic diversity value was 0.639 and the power of discrimination was 0.804.3. Compared with observed number of alleles and allele frequency in ethnic difference, result was appeared to be similar to that of Japanese and Asians, while was appeared to be much different to that of Blacks and Caucasians in the observed number of alleles and frequency of allele 3.2, 5, 7. From the above result of this investigation, the allelic frequency of STR F13A01 locus in the Korean was considerd to be useful for individual identification and parentage testing as a database.

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New Perspectives in Pediatric Nonalcoholic Fatty Liver Disease: Epidemiology, Genetics, Diagnosis, and Natural History

  • Ko, Jae Sung
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.22 no.6
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    • pp.501-510
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    • 2019
  • Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in children. The global prevalence of pediatric NAFLD from general populations is 7.6%. In obese children, the prevalence is higher in Asia. NAFLD has a strong heritable component based on ethnic difference in the prevalence and clustering within families. Genetic polymorphisms of patatin-like phospholipase domain-containing protein 3 (PNPLA3), transmembrane 6 superfamily member 2, and glucokinase regulatory protein (GCKR) are associated with the risk of NAFLD in children. Variants of PNPLA3 and GCKR are more common in Asians. Alterations of the gut microbiome might contribute to the pathogenesis of NAFLD. High fructose intake increases the risk of NAFLD. Liver fibrosis is a poor prognostic factor for disease progression to cirrhosis. Magnetic resonance spectroscopy and magnetic resonance proton density fat fraction are more accurate for steatosis quantification than ultrasound. Noninvasive imaging methods to assess liver fibrosis, such as transient elastography, shear-wave elastography, and magnetic resonance elastography are useful in predicting advanced fibrosis, but they need further validation. Longitudinal follow-up studies into adulthood are needed to better understand the natural history of pediatric NAFLD.

A Symptomatic Reading of 'Discrimination' and 'Difference' in A Gesture Life (『제스처 라이프』에 나타난 '차별'과 '차이'의 징후적 읽기)

  • Rhee, Suk Koo
    • Journal of English Language & Literature
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    • v.56 no.5
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    • pp.907-930
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    • 2010
  • Most previous studies on A Gesture Life focused on illuminating the role and significance of Kkutaeh, the Korean comfort woman, whom Hata runs across at a military camp in the Burmese jungle. For instance, Carroll Hamilton argues that the return of Kkutaeh as a traumatic subject disrupts Hata's nationalist narrative, causing the protagonist's eventual failure at national enfranchisement. However, this paper focuses on Hata's relationship with Bedley Run, the sleepy suburban white town, in which the protagonist settles down right after immigration to the US. The racial/racist nature of Bedley Run has not received due critical attention, although a few studies on the novel saw Hata's gestures as a survival tactic deployed against the hostile environment of his new host society. This paper, resorting to Pierre Macherey's thesis on symptomatic reading, exposes what Hata, the narrator/protagonist, hides from his readers concerning his status in his muchbeloved town; and it also explores the subversive significance of Hata's ethnic memories. The aim of this study is, after all, to map both the subversive possibilities and the limitations of Hata's immigrant narrative as a bildungsroman.

The Latin American Culture in Fashion Designs in 2000's (2000년 이후 패션 디자인에 나타난 라틴 아메리카 문화)

  • Choi, Ho-Jeong
    • Journal of the Korean Society of Costume
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    • v.57 no.4 s.113
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    • pp.159-172
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    • 2007
  • For the study on the Latin American culture reflected in fashion designs since 2000, the applications of Latin American culture shown in the four major collections from 2000 S/S to 2005 F/W (110 pieces) and some African designers' collections (157 pieces) have been analyzed and compared in three categories - forms, patterns and accessories. First, in the formal application of traditional clothes, the traditional elements of Indio culture are utilized in both the four major collections (76.8%) and the Latin American designers' collection (77.1%). Quechquemitl, the traditional Indio clothes are utilized in various forms in the four major collections, while the Latin American designers adopt various forms of traditional clothes, such as quechquemitl, camisa and pollera. Second, in the textile design, the patterns from Indio's traditional textile design are utilized in both the four major collections (68.7%) and the Latin American designers's collections (5.6%). The remarkable difference between the Latin American designers and the western designers is that the former like to mix the simple and primitive Indio culture with the colorful Iberian culture, and to utilize various patterns of feather, which is an important symbol in the traditional culture, expressing tradition in the modern touch. On the other hand, the western designers change the primitive and handcraft feel of Indio patterns into colorful ones, or mix the colorful Spanish-style flower patterns with primitive and passionate feel. Third, simple and handcraft feel of Indio accessories are utilized in modern fashion in both the four major collections and the Latin American designers' collections. The most remarkable difference between the two group of designers' collections is that various feather patterns are used in Latin American designers' collection, while the accessories reminding of relics of Maya and Inca are widely used in the four major collections.

The chronology of second molar development in Brazilians and its application to forensic age estimation

  • Almeida, Manuella Santos Carneiro;Pontual, Andrea Dos Anjos;Beltrao, Rejane Targino;Beltrao, Ricardo Villar;Pontual, Maria Luiza Dos Anjos
    • Imaging Science in Dentistry
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    • v.43 no.1
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    • pp.1-6
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    • 2013
  • Purpose: This study investigated the possible correlation between the mineralization of the second molars and the chronological age of a sample population of the state of Paraiba, Brazil. Materials and Methods: One thousand eight hundred fifty-four digitized panoramic images using a scanner of a private dental radiology service were obtained in six months. Of these, 457 were selected from patients aged 4.6 to 16 years who met certain criteria. The images were assessed twice by a radiologist with 5 years experience. A minimum interval of 30 days between the evaluations of the same patient was established. To analyze the relationship between chronological age, calcification level proposed by Demirjian et al in 1973, gender, and tooth, a multiple linear regression model was adjusted, taking age as the response variable (p<0.05). Results: The gender and calcification level were significantly correlated with the age of the patients (p<0.05). There was a significant difference between the average age of the patients' upper teeth compared to the lower ones in both genders (p<0.05). The dental development occurred earlier in female individuals than in male ones, and there was no significant difference between the right and left second permanent molars. Conclusion: It was observed that ethnic variables are related to certain parameters of age and sex identification in the Brazilian population, providing important information for forensic evaluations.

Comparison of cephalometric norms between Mongolian and Korean adults with normal occlusions and well-balanced profiles (조화로운 측모를 가진 몽골인과 한국인 성인 정상교합자의 측모두부계측방사선학적 비교 연구)

  • Kim, Ji-Hwan;Gansukh, Odontuya;Amarsaikhan, Bazar;Lee, Sin-Jae;Kim, Tae-Woo
    • The korean journal of orthodontics
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    • v.41 no.1
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    • pp.42-50
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    • 2011
  • Objective: The purposes of this study were to establish cephalometric norms of Mongolian adults, which have not previously been reported in orthodontic journals, and to compare them with cephalometric norms of Korean adults. Methods: Lateral cephalometric radiographs of 74 Mongolian adults (35 men, 39 women) and 95 Korean adults (52 men, 43 women) with normal occlusions and well-balanced lateral profiles were obtained. The subjects were chosen by orthodontists of the same ethnic background. Forty craniofacial variables were measured, and groups were compared by analysis of covariance. Results: The cephalometric norms for male and female Mongolian and Korean adults with normal occlusions and well-balanced lateral profiles were established. Sexual dimorphism was found in linear skeletal measurements and vertical skeletal relationships. Compared with Korean adults, Mongolian adults had shorter anterior facial height, more prominent chins, and more upright upper incisors. There were few differences in soft tissue measurements. The differences were statistically significant, but their clinical importance may be limited. Conclusions: Cephalometric differences can be considered, but little difference may exist in the orthodontic diagnosis and treatment planning of Mongolian and Korean adults.

Comparison of arch forms between Korean and Japanese in Class I, II, and III malocclusion (한국인과 일본인 부정교합자의 하악 치열궁 헝태 비교)

  • Lee, Chae-Hyung;Mo, Sung-Seo;Kang, Yoon-Goo;Nojima, Kunihiko;Kim, Young-Ho;Kook, Yoon-Ah
    • The korean journal of orthodontics
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    • v.37 no.5
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    • pp.364-375
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    • 2007
  • The purpose of this study was to compare arch dimensions and frequency distribution of arch forms between Korean and Japanese Class I, II, and III malocclusion groups. Methods: The sample consisted of 368 Korean cases (114 Class I, 119 Class II, and 135 Class III malocclusion) and 160 Japanese cases (60 Class I, 50 Class II, and 50 Class III malocclusion). The most facial portion of 13 proximal contact areas was digitized from photocopied images of the mandibular dental arches. Clinical bracket slot points were calculated for each tooth based on mandibular tooth thickness data. Four linear and two proportional measurements were taken. Measurements are statistically analyzed in each malocclusion group. The dental arches were classified into square, ovoid, and tapered forms to determine and compare the frequency distributions between the two ethnic groups. Results: The findings of this study showed that Japanese females in Class I and II groups had a statistically significant narrower mandibular dental arch width compared with the Japanese males, Korean males and Korean females. But in the Class III group, there was no significant difference in the mandibular dental arch size according to the two ethnic groups and genders. Conclusions: The majority of Koreans and Japanese in all the malocclusion groups exhibited square and ovoid arch forms. The most frequent arch forms found in Koreans was square but ovoid for Japanese.

Sex Preference and Sex Differentials in Child Mortality: A Comparative Analysis of Koreans, Hans and Dais in China (성선호에 따른 유아의 성별 차별사망력: 중국의 조선족, 한족과 다이족의 비교분석)

  • 김두섭
    • Korea journal of population studies
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    • v.23 no.2
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    • pp.143-166
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    • 2000
  • This paper attempts to explore the relation between health care availability and child mortality among ethnic groups with different cultural traditions of sex preference. Micro-data from the 1990 Census of China for Yanbian and Xishuangbanna Prefectures are used. Based on the analysis of data for Koreans, Hans, and Dais in these prefectures, a new model explaining the relation between sex preference, health care. and differentials in child mortality is proposed in this paper. In societies, where health care is easily available, the level of child mortality is not likely to be a function of sex preference. In societies where there is little availability of health care, members of ethnic groups with strong sex preference do whatever possible to assure survival of their children of the preferred sex. But actions to assure survival of children of the sex not preferred by their parents depend on the costs involved and other considerations. Therefore, the level of child mortality for the preferred sex is likely to be substantially lower than that of the not-preferred sex. However, as availability of health care improves and the cost of obtaining health care becomes lower, survival of children of the not-preferred sex are likely to improve. It is generally agreed that Koreans and Hans show strong son preference, while Dais have cultural traditions of daughter preference. In Yanbian, where virtually all children receive health care whenever it is needed, Korean females and Han females show lower child mortality than their male counterparts, although the difference is not found to be significant for Koreans. In Xishuangbanna, where there is little availability of health care, Dai males show markedly higher child mortality than Dai females, and Han females have higher child mortality than Han males. However, small improvements in the availability of health care in Xishuangbanna translate into substantial improvements in survival of male children for Dais, and survival of female children for Hans.

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Analysis of Monocyte Chemoattractant Protein 1(MCP-1) Polymorphism in Korean Patients with Asthma (한국인 천식환자의 Monocyte chemoattractant protein 1(MCP-1) 유전자 다형성에 대한 분석)

  • Hwang, Woo-Suk;Jeong, Seung-Yeon;Kim, Jin-Ju;Jung, Hee-Jae;Jung, Sung-Ki
    • The Journal of Internal Korean Medicine
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    • v.29 no.1
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    • pp.32-41
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    • 2008
  • Background : Monocyte chemoattractant protein-1(MCP-1), one of the CC chemokines, appears to play a significant role in asthma pathogenesis. It was reported that polymorphism in the MCP-1(-2518 A/G promoter) was associated with asthma in Caucasians, but the association of this polymorphism and asthma patients in the Korean population has not yet been clarified. Objective : We investigated the possible association between 2 polymorphisms (-2518 A/G promoter and Cys35Cys) and asthma patients in a Korean population. Materials and Methods : DNA samples were obtained from 86 Korean asthma patients and 270 healthy controls. MCP-1 genomic variants (-2518 A/G promoter and Cys35Cys polymorphism) were detected by PCR-RFLP. Level of MCP-1 was measured by ELISA for each genotype (n=8) (AA, AG, GG) and allele types of -2518 A/G promoter polymorphism for control subjects. Results : The Cys35Cys polymorphism was associated with asthma patients in Korean population [genotype distribution ($X^{2}=16.011$, P<0.001)]. Comparison of the two groups revealed no detectable differences in genotype and allele frequencies of the -2518 A/G polymorphism. Haplotype frequencies analysis revealed significant difference $(X^{2}=51.70$, P<0.001). MCP-1 serum level of subjects with G genotype of -2518 A/G promoter polymorphism was statistically higher than that with AA genotype (P<0.05). Conclusion : Our data indicate that no association exists between the MCP-1 -2518 A/G polymorphism and asthma susceptibility in the Korean population. However, it is noteworthy that the high prevalence of the -2518 G allele in the Korean population suggests a potentially important ethnic variation in the regulation of MCP-1 production. This variation must be considered in gene-association studies in different ethnic populations.

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A Study on the Relationship of Stereotypical Attitudes of Middle School Students toward Saeteomins (North Korean Refugees) to Knowledge of North Korea (중학생의 북한에 대한 지식과 새터민에 대한 고정관념의 관계에 대한 연구)

  • Yoon, Ok-Kyong
    • Journal of the Korean association of regional geographers
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    • v.15 no.6
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    • pp.820-833
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    • 2009
  • Multiculturalism in education are different from each countries, It is needed to practice multicultural education in many fields facing changes to multicultural society in Korea. This study demonstrates on the relationship of social friendliness and stereotypical attitudes toward Saeteomins (North Korean refugees) to the knowledge of North Korea. Saeteomins are special in the respect of linguistic and ethnic homogeneity of Korea. They have to adapt themselves to new circumstances like other immigrants from abroad. At the same time they have cultural senses of difference to live in a divided country in spite of ethnic homogeneity. It is important to get openminded attitudes to be receptive to cultural diversity in the respect of getting multicultural sensitivity. On account of a growing migration of Saeteomins family, Saeteomin students have difficulties in adapting to Korean society. This study focuses on the point of middle school (general) students' view to Saeteomin students, who have experiences to meet each other. There are three categories of contents knowledge, common sense of North Korea and social issues related to North Korea in this paper. All of them are significant to social friendliness and stereotypical attitudes toward Saeteomins to the knowledge of North Korea. That is important point to contents construction in curriculum about North Korea. This study is meaningful to find the potential to link contents knowledge of subject to multicultural education practice in the process of curriculum change especially in relation to the knowledge of North Korea in 2007.

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