• 한국균학회지
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• 제46권3호
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• pp.307-314
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• 2018

본 연구는 알코올 발효능이 우수한 야생 효모를 막걸리 발효에 응용할 목적으로 충남 예산군 예당저수지 야생화에서 분리한 비병원성 야생 효모들 중 에탄올 생산 우수 효모로 선발한 Aureobasidium pullulans P-1의 균학적 특성과 막걸리 발효 조건을 조사하였다. A. pullulans P-1는 출아에 의해 영양증식을 하였고 자낭포자를 생성하는 유포자 효모로서 내당성과 에탄올 내성이 강한 호염성 야생 효모이었다. A. pullulans P-1의 yeast extract-peptone-dextrose 배양액을 주모로 증자미와 입국과 물이 혼합된 술밑에 5% 첨가한 후 $25^{\circ}C$에서 1~10일간 발효시키면서 발효 중의 이화학적 성질의 변화를 조사한 결과, 에탄올 함량은 $25^{\circ}C$로 10일간 발효시켰을 때 가장 많은 8.45%를 생성하였고 관능 특성이 우수하였으며 항고혈압 활성 안지오텐신 전환효소 저해활성이 71.1%로 높았다.

• 대한본초학회지
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• 제33권3호
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• pp.1-9
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• 2018

Objectives : In Korean medicine, a prescription of Sinsun-yukza-hwan (Shenxian-liuzi-wan, SSY) has been used in clinic for treatment of alopecia via oral. This study was performed to determine transdermal effects of the ethanol extract from SSY on hair growth and -related gene expressions in mice. Methods : We analyzed index compound, 5-hydroxy-methyl-2-furaldehyde (HMF), in SSY extract by ultra performance liquid chromatography (UPLC). 6 weeks old C57BL/6 mice with removed hair were used as an alopecia animal model. Mice were divided into 3 experimental groups including normal (3 water: 1 ethanol: 2 polyethylene glycol mixture as a vehicle), SSY extract and 5% minoxidil (as a positive control), treated groups. SSY was applied topically on the hair-shaved skin of C57BL/6 mice every day for 15 days. The color, thickness and density of hair were monitored every $5^{th}$ day by naked eye, photograph and phototrichogram using folliscope. Also hair growth-associated gene expressions were measured by immunoblotting assay. Results : Hair density of minoxidil or SSY-treated group was significantly increased compared to that of vehicle application on the $15^{th}$ day, respectively. And hair thickness of minoxidil and SSY groups was increased compared to that of vehicle treated group on the $15^{th}$ day, respectively. Induction of insulin-like-growth factor 1(IGF-1) and vascular endothelial growth factor (VEGF) were also significantly accelerated by SSY extract compared to those of vehicle-applied group. Conclusions : These results provide scientific evidence to support the potent multi-application of SSY as a cosmeceutical material for promoting hair growth.

• Bulletin of the Korean Chemical Society
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• 제31권5호
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• pp.1275-1279
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• 2010

We have carried out the surface modification of photocatalytic $TiO_2$ with triethoxysilane through dehydrogenation reaction and characterized the modified photocatalyst by spectroscopic methods, such as FT-IR, solid-state $^{29}Si$ MAS NMR, XPS, and XRF, etc. We also examined photocatalytic activity of the immobilized photocatalytic titanium dioxide with triethoxysilane by decolorization reaction of dyes such as cong red and methylene blue under visible light. Dispersion test showed that the photocatalytic titanium dioxide immobilized with triethoxysilane group has kept higher dispersibility than titanium dioxide itself. No appreciable precipitation takes place even after standing for 24 h in the 4:6 mixture ratio of ethanol and water.

• 한국막학회:학술대회논문집
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• 한국막학회 1996년도 추계 총회 및 학술발표회
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• pp.86-87
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• 1996

IPN (Interpenetrating Polymer Network) is a mixture of two or more crosslinked polymers with physically interlocked network structures between the component polymers. IPN can be classified as an alloy of thermosets and has the characteristics of thermosets such as the thermal resistance and chemical resistance and also has the characteristics of polymer alloys with enhanced impact resistance and amphoteric properties. The physical interlocking during the synthesis restricts the phase separation of the component polymer with chemical pinning process, thus the control of morphology is possible through variations of the reaction temperature and pressure, catalyst concentration and crosslinking agent concentration. Finely dispersed domain structure can be obtained through IPN synthesis of polymer components with gross immiscibility. In membrane applications, particularly for the separation of liquid mixtures, crosslinked polymer component with specific affinity to the permeate is needed. With the presence of the permeant-inert polymer component, the mechanical strength and the selectivity of the membranes are enhanced by restricting the swelling of the transporting polymer component networks.

• 대한화학회지
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• 제9권1호
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• pp.8-15
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• 1965

一般式中의 potential energy 變數로서 ${\sigma}$ Y를 使用할 수 있음을 밝혔고 또 關係式의 反應機構上의 意義를 論하였다. Benzyl chlorides의 solvolysis反應 data를 適用함으서 物質常數 ${\alpha}'$는 2個의 뚜렷한 系列을 形成하며 置換基常數 ${\sigma}$와는 各系列마다 別途로 直線關係를 가지며 이로서 $S_N1$으로부터 $S_N2$로의 反應機構의 變化를 알 수가 있었다.

• Korean Chemical Engineering Research
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• 제54권6호
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• pp.792-799
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• 2016

Monodisperse silica nanospheres were synthesized by Stober method using rotating cylinder systems with batch or continuous manner. The particle size could be controlled by adjusting the reactant compositions such as the amount of monomer, catalyst, and water in the reaction mixture. The size and monodispersity of the ceramic particles could be controlled by changing the reaction medium with different alcohols other than ethanol or changing the reaction temperature. The effect of Taylor number (Ta) on the average diameter and standard deviation of silica particles were also studied by adjusting the rotation speed of inner cylinder, and the maximum diameter of particles was observed at Ta ${\approx}3,000$.

• Fibers and Polymers
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• 제2권2호
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• pp.58-63
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• 2001

Silk fibroin (SF) was dissolved in calcium chloride/ethanol/water mixture(1/2/8 in mole ratio) at $70^{\circ}C$ for 4h. The dissolved silk fibroin was regenerated by casting the dialyzed solution into films. The films were treated with 50% aqueous solution of methanol for different times, and their antithrombogenicity was evaluated by in vivo tests. In vivo blood tests were made by a method of peripheral vein indwelling suture. It was found that the silk fibroin had a good antithrombogenicity and an absorbability even though the polymer showed foreign body reaction. Finally, the blood compatibilty of silk fibroin films which were subjected to structural change by the methoanl treatment, was examined in connection with their interfacial surface energy, and a correlation between these properties was found to be present.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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• pp.117-117
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• 2002

Paclitaxel isolated from the pacific yew tree, Taxus brevifolia, is microtuble-stabilizing agent that has a promising anticancer activity against a wide variety of tumors such as ovarian, breast and lung cancers. Because of its poor water solubility, paclitaxel is currently formulated in a mixture of polyoxyethyleneglycerol triricinoleate 35 (Cremophor EL) and dehydrated ethanol USP (1:1 v/v).(omitted)

• Preventive Nutrition and Food Science
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• 제22권2호
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• pp.100-106
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• 2017

To elucidate new biological ingredients in cold-brew coffee extracted with cold water, crude polysaccharide (CCP-0) was isolated by ethanol precipitation, and its immune-stimulating activities were assayed. CCP-0 mainly comprised galactose (53.6%), mannose (15.7%), arabinose (11.9%), and uronic acid (12.4%), suggesting that it might exist as a mixture of galactomannan and arabinogalactan. CCP-0 significantly increased cell proliferation on both murine peritoneal macrophages and splenocytes in a dose dependent manner. CCP-0 also significantly augmented nitric oxide and reactive oxygen species production by murine peritoneal macrophages. In addition, macrophages stimulated by CCP-0 enhanced production of various cytokines such as tumor necrosis factor-${\alpha}$, interleukin (IL)-6, and IL-12. In an in vitro assay for intestinal immune-modulating activity, CCP-0 showed higher bone-marrow cell-proliferation activity through Peyer's patch cells at $100{\mu}g/mL$ than the negative control. These results suggest that CCP-0 may potentially enhance macrophage functions and the intestinal immune system.

• 동력기계공학회지
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• 제2권1호
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• pp.25-30
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• 1998

In order to investigate the droplet size distribution and Sauter Mean Diameter in a ultra high pressure diesel spray, fuel was injected with ultra high pressure into the environments of high pressure and room temperature by an Electronic Hydraulic Fuel Injection System. Droplet size was measured with the immersion liquid sampling technique. The immersion liquid was used a mixture of water-methycellulose solution and ethanol. The Sauter Mean Diameter decreased with increasing injection pressure, with a decrease environmental pressure (back pressure) and nozzle diameter. Increasing the injection pressure makes the fuel density distribution of the spray more homogeneous. An empirical correlation was developed among injection pressure, air density, nozzle diameter and the Sauter Mean Diameter of spray droplets.