• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2012.05a
• /
• pp.191-193
• /
• 2012

the existing developed route guidance services for the visually impaired aids for using RFID tags attached to the cane, the extent to which the cover blocks and RF communication was a simple walking guide service. It has a detection range of RFID readers in short, clear obstacles to location, size and shape can not be determined. And the risk of escape routes in case of questions or directions Measures are urgently needed. Today, due to the Smart Device Development convenience to users and offers many benefits. And the Android platform, Client and Server (PC) between the socket stream, using real-time video and voice information, location information by sending a dangerous situation for the visually impaired to take immediate action on the system and 1: N is to implement the service.

• IMMUNE NETWORK
• /
• v.5 no.1
• /
• pp.1-10
• /
• 2005

Background: Chronic infection with hepatitis B virus (HBV) affects about 350 million people worldwide, which have a high risk of development of cirrhosis and hepatocellular carcinoma. Treatment of chronic HBV infection relies on IFN-${\alpha}$ or lamivudine. However, interferon-${\alpha}$ is effective in only about 30% of patients. Also, the occurrence of escape mutations limits the usage of lamivudine. Therefore, the development and evaluation of new compounds or approaches are urgent. Methods: We comparatively evaluated DNA and adenoviral vaccines expressing HBV antigens, either alone or in combined regimens, for their ability to elicit Th1-type immune responses in Balb / c mice which are believed to be suited to resolve HBV infection. The vaccines were tested with or without a genetically engineered IL-12 (mIL-12 N220L) which was shown to enhance sustained Th1-type immune responses in HCV E2 DNA vaccine. Results: Considering the Th1-type cytokine secretion and the IgG2a titers, the strongest Th1-type immune response was elicited by the DNA prime-adenovirus boost regimen in the presence of mIL-12 N220L. In addition, the codelivery of mIL-12 N220L modulated differentially the immune responses by different vaccination regimens. Conclusion: Our results suggest that the DNA prime-adenovirus boost regimen in the presence of mIL-12 N220L may be the best candidate for HBV vaccine therapy of the regimens tested in this study and will be worthwhile being evaluated in chronic HBV patients.

• Journal of the Korean housing association
• /
• v.25 no.5
• /
• pp.21-32
• /
• 2014

This research intends to discover the housing conditions of the elderly in rural area in South Korea, and identify measures to improve the conditions for an independent and safe life of seniors. This research conducted both survey research and experimental study. The survey interviewed 1,000 elderly people over 65 in farming areas across the country based on random selection from Census 2010 and sampling by regional size and administrative unit (Eup, Myeon, Li) to reflect the regional characteristics more accurately. The data was analyzed using SPSS 18.0 program. The experimental study identified the housing elements that may threaten the life of seniors based on a complete survey on households of elderly people over 65 in a selected typical rural village. As a result, the most inconvenient and threatening factor in the housing facilities appears to be the floor level difference. It was identified that most houses had the risk of falling due to the differences of the floor level between indoor and outdoor, and slippery floor materials. The squat toilets also bring inconvenience not only to the seniors with limited mobility but also to healthy elderly people. In particular, as most bathroom doors opened inward, it may be difficult to escape from or rescue someone in an emergency of falling, fainting or exhaustion.

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.63 no.9
• /
• pp.1286-1293
• /
• 2014

Typically, studies through the simulation system have been progressed, because the evaluation of the driver's arousal state about the service of a actual train has risk of safety for the driver. When configured event same as the real in simulation system, the ability to cope with an accident situation may be the same each other. But the difference in the state of tension or arousal will occur. In this study, requested to cooperate with the railways in order to escape from these constraints, and the target of the experiment was to real engineer service. I was set about experiment when the train was stopped as safe as possible. As a result, the beta wave of EEG signals that representing complex calculations or anxiety is increased rapidly on the basis of a flag station from at the time of departure. The size of the electrodermal activity signal in response to movement of the body gave a noticeable. In terms of HRV, if the train approach a flag station gradually and the R-R interval is narrowed. So that the driver can be estimated as arousal state. In accordance with this study, if the quantitative standard of arousal state be based on the driver's biosignals will provide, it will be able to take advantage of development the system that would prevent train accidents caused by human error.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.14
• /
• pp.6155-6158
• /
• 2015

Background: The human leukocyte antigen-G (HLA-G) gene is highly expressed in cancer pathologies and is one strategy used by tumor cells to escape immune surveillance. A 14-bp insertion/deletion (InDel) polymorphism of the HLA-G gene has been suggested to be associated with HLA-G mRNA stability and the expression of HLA-G. The aim of present study was to assess any genetic association between this polymorphism and breast cancer among Iranian-Azeri women. Materials and Methods: In this study 227 women affected with breast cancer, in addition to 255 age-sex and ethnically matched healthy individuals as the control group, participated. Genotyping was performed using polymerase chain reaction and electrophoresis assays. The data were compiled according to the genotype and allele frequencies, compared using the Chi-square test. Statistical significance was set at P<0.05. Results: In this case-control study, no significant difference was found between the case and control groups at allelic and genotype levels, although there is a slightly higher allele frequency of HLA-G 14bp deletion in breast cancer affected group. However,when the stage I subgroup was compared with stage II plus stage III subgroup of affected breast cancer, a significant difference was seen with the 14 bp deletion allele frequency. The stage II-III subgroup patients had higher frequency of deletion allele (57.4% vs 45.8%) than stage I cases (${\chi}^2=4.16$, p-value=0.041). Conclusions: Our data support a possible action of HLA-G 14bp InDel polymorphism as a potential genetic risk factor for progression of breast cancer. This finding highlights the necessity of future studies of this gene to establish the exact role of HLA-G in progression steps of breast cancer.

• Korean Journal of Childcare and Education
• /
• v.9 no.1
• /
• pp.129-148
• /
• 2013

The purpose of this study is to examine the relationships between fathers and children with Internet addiction. To achieve the goal, researchers chose face to face interview methods with 12 children who had been considered'at risk'with Internet addiction. More specifically, examiners conducted individual in-depth interviews with 12 children associated with Internet addiction for 30~40 minutes during four sessions through structured questions and non-structured questions. After collecting data, examiners conducted a categorical analysis based on collected data. Finally, the research results, discovered in this research, were as follows: First, the Internet set up the inter-generational barrier in the relationship between father and child, second, children took an interest in the Internet instead of their busy father, Third, the Internet played the role of a place to escape from the awkwardness with their father, fifth, fathers were not able to control the Internet use of their children. Based on the research results, this study suggests a desirable behavior pattern for fathers which can be conducive to children with Internet addiction and their fathers along with a follow-up study.

• Journal of the Society of Naval Architects of Korea
• /
• v.59 no.6
• /
• pp.385-392
• /
• 2022

Naval ship could face a variety of threats in isolated seas. In particular, fires and flooding are defined as disasters that are very likely to cause irreparable damage to ships. These disasters have a very high risk of personal injury as well. Therefore, when a disaster occurs, it must be quickly suppressed, but if there are people in the disaster area, the protection of life must be given priority. In order to quickly evacuate the ship crew in case of a disaster, we would like to propose a plan to quickly explore the evacuation route even in urgent situations. Using commercial escape simulation software, we obtain the data for deep neural network learning with simulations according to aisle characteristics and the properties and number of evacuation person. Using the obtained data, the passage prediction model is trained with a deep learning, and the passage time is predicted through the learned model. Construct a numerical map of a naval ship and construct a distance matrix of the vessel using predicted passage time data. The distance matrix configured in one of the path search algorithms, the Dijkstra algorithm, is applied to explore the evacuation path of naval ship.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
• /
• v.7 no.12
• /
• pp.947-954
• /
• 2017

In case of a fire in urban large structures such as super high-rise buildings, evacuation guidance must be provided to the occupants in order to minimize human deaths and injuries. Therefore, it is essential to provide emergency evacuation guidance when a major fire occurs. In order to effectively support evacuation guidance, it is important to identify major items such as fire location, occupant position, escape route, etc. Also, it is important to quickly identify evacuation areas where residents can safely evacuate from a fire. In this paper, we analyze the CCTV video and propose a method of measuring visibility of the evacuation zone from the smoke caused by the fire in order to determine the safety of evacuation area. To do this, we first extract the background video from the smoke video to measure the visibility of the specific area due to smoke. After generating an edge-extracted image for the extracted background video, the degree of visibility is measured by calculating the change in the edge strength due to smoke.

• Korean Journal of Social Welfare Studies
• /
• v.42 no.1
• /
• pp.243-278
• /
• 2011

The main purpose of this paper is to understand the process of the poverty exit across generations through the live experience based on the grounded theory analysis of the in-depth interview. We find that poverty means a lack of achievement and freedom of agency that is a level of control about resource and situation. So exit of poverty across generations is the state that is not only to achieve functioning but also to recover capabilities. Based on this result, central phenomena of the intergenerational exit process of poverty are support from relation and continuous transition at each stage in life. Even if this central phenomenon is an important event, it has the incomplete attribute. Because support from relation is beyond individual scope of control and participants can't escape second labor market as they don't have enough time in the process of transition. Therefore, this paper suggests that the expansion of state welfare and strategy should support transition as policy priorities to minimize limitation of relation and risk of income loss.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.8
• /
• pp.3173-3181
• /
• 2015

Background: It has been hypothesized that IL-18 (pro-) and IL-10 (anti-) inflammatory genetic variants at -607 C/A-137G/C and -819C/T,-592C/A, respectively, may generate susceptibility and severity risk with various modes of tobacco exposure in prostate carcinoma (PCa) patients. IL-18 is a pro-inflammatory cytokine expressed on various cells including prostate gland elements, and is a key mediator of immune responses with anti-cancerous properties. IL-10 is an anti-inflammatory cytokine that is associated with tumour malignancy which causes immune escape. Materials and Methods: The present study was conducted with 540 subjects, comprising 269 prostate carcinoma patients and 271 controls. Genotyping was performed by PCR-RFLP and confirmed by real time PCR probe-based methods. Results: The findings indicated that the mutant heterozygous and homozygous genotype CC and GC+CC showed significant negative associations (p=0.01, OR=0.21; 95% CI: 0.08-0.51 and p=0.011, OR=0.43; 95% CI: 0.22-0.81, respectively) thus, less chance to be diagnosed as cancer against GG genotype of tobacco smoking patients. In addition, a heterozygous GC genotype at the same locus of IL-18 pro-inflammatory cytokine may aggravate the severity (OR=2.82; 95%CI 1.09-7.29 :p=001) so that patients are more likely to be diagnosed in advanced stage than with the GG wild homozygous genotype. Our results also illustrated that anti-inflammatory cytokine (IL-10) genetic variants, although showing no significant association with susceptibility to cancer of the prostate, may gave profound effects on severity of the disease, as -819 TC (OR=4.60; 95%CI 1.35-15.73), and -592 AC (OR=5.04; 95%CI 1.08-25.43) of IL-10 in tobacco chewers and combined users (both chewers and smokers) respectively, are associated with diagnosis in more advanced stage than with other variants. Conclusions: We conclude that promoter genetic variants of IL-18 and IL-10 with various modes of tobacco exposure may affect not only susceptibility risk but also severity in prostate cancer.