• Title/Summary/Keyword: Erythrina alkaloids

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Constituents of Erythrina caffra Stem Bark Grown in Egypt

  • El-Masry, Sawsan;Hammoda, Hala M.;Zaatout, Hala H.;Alqasoumi, Saleh I.;Abdel-Kader, Maged S.
    • Natural Product Sciences
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    • v.16 no.4
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    • pp.211-216
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    • 2010
  • A new 3-indolyl propionate alkaloid; (-) abrine (1), was isolated from the alcohol extract of Erythrina caffra stem bark together with the alkaloid (-) hypaphorine (2). Phytochemical investigation of the chloroform extract led to the isolation of one fatty alcohol; 1-octacosanol, isolated for the first time from genus Erythrina, two dienoid alkaloids; erythraline and erysodine, and three isoflavonoids; 3S (+) 2'-O-methylphaseollidinisoflavan (3), (6aR, 11aR)- 3-hydroxy-10-dimethylallyl-9-methoxypterocarpan, known as sandwicensin (4) and 3R (-) rythbidin A (5). It is worth mentioning that this is the first report for the isolation of these isoflavonoids from E. caffra. The absolute configuration of 3S (+) 2'-O-methylphaseollidinisoflavan (3) was not previously reported. The isolated isoflavonoids showed promising antibacterial activity against Staphylococcus aureus.