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Constituents of Erythrina caffra Stem Bark Grown in Egypt  

El-Masry, Sawsan (Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University)
Hammoda, Hala M. (Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University)
Zaatout, Hala H. (Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University)
Alqasoumi, Saleh I. (Department of Pharmacognosy, College of Pharmacy, King Saud University)
Abdel-Kader, Maged S. (Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University)
Publication Information
Natural Product Sciences / v.16, no.4, 2010 , pp. 211-216 More about this Journal
Abstract
A new 3-indolyl propionate alkaloid; (-) abrine (1), was isolated from the alcohol extract of Erythrina caffra stem bark together with the alkaloid (-) hypaphorine (2). Phytochemical investigation of the chloroform extract led to the isolation of one fatty alcohol; 1-octacosanol, isolated for the first time from genus Erythrina, two dienoid alkaloids; erythraline and erysodine, and three isoflavonoids; 3S (+) 2'-O-methylphaseollidinisoflavan (3), (6aR, 11aR)- 3-hydroxy-10-dimethylallyl-9-methoxypterocarpan, known as sandwicensin (4) and 3R (-) rythbidin A (5). It is worth mentioning that this is the first report for the isolation of these isoflavonoids from E. caffra. The absolute configuration of 3S (+) 2'-O-methylphaseollidinisoflavan (3) was not previously reported. The isolated isoflavonoids showed promising antibacterial activity against Staphylococcus aureus.
Keywords
Erythrina caffra; alkaloids; isoflavanoids; Staphylococcus aureus;
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