• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.17 no.2
• /
• pp.153-158
• /
• 2004

Background and Objective: Erythema multiforme(EM) is related disorders of skin and mucous membranes which is typically associated with antecedent medications or infections. etc. EM is an erythematous maculopapular cutaneous eruption of variable form. However, the pathophysiology of the EM remains obscure. Treatment at present is symptomatic and supportive. There is no report on EM treated with oriental medical treatment. Methods: We conducted one patient with EM seen at Won-Kwang University Kwang-Ju Oriental Medical Hospital in 2004. We treated EM in a twenty-two years old man by a herbal medicine(Joa-Chang-Bang), a herbal medicine for external use, acupunture, moxa, COTDE-made cosmetics, and P-Tx(carbon). Conclusions. We had a significant results. So we report this case to estimate the efficiency of oriental medical treatment and management on EM.

• Medical Lasers
• /
• v.9 no.1
• /
• pp.84-87
• /
• 2020

Post-acne erythema (PAE) is one of the major problems during or after treatment of acne vulgaris with any modality. A variety of therapeutic options have been described with various clinical outcomes and side effects. We report here on treating a patient with PAE using 595-nm picosecond-domain neodymium:yttrium-aluminum-garnet (Nd:YAG) laser. After four sessions of treatment, the patient displayed nearly complete improvement and no remarkable adverse effects. To the best of the authors' knowledge, this is the first case of the effective treatment of PAE using a 595-nm picosecond-domain Nd:YAG laser. We recommend that using a 595-nm picosecond-domain Nd:YAG laser can be both an effective and safe treatment option for treating PAE.

• Journal of Veterinary Clinics
• /
• v.19 no.2
• /
• pp.186-190
• /
• 2002

This crossover study was performed in order to compare the effects of cetirizine, loratadine, and terfenadine in canine skin. Five healthy dogs were used. Cetirizine 0.5 mg/kg, loratadine 5 mg/kg and terfenadine 5 mg/kg were administered orally 4 hours before the experiment. Erythema indices and wheal size were assessed by Hexameter ($MX^{\circledR}$ 18, CK, Germany) and skin reaction guide, respectively. Cetirizine-induced erythema inhibition was generally higher than other drugs and was significantly different from placebo. Cetirizine was superior to placebo at 3, 4, 5, 6, 7, and 8 minutes (p< 0.01). Cetirizine also was superior to placebo at 9 minutes (p< 0.05). Loratadine and terfenadine erythema inhibition were better than after placebo treatment from 4 to 9 minutes, but erythema index of terfenadine at 7 minutes was not observed probability of 95% and 99%. At 10 minutes, intradermal injection of the histamine caused a mean wheal dimension for placebo, cetirizine, loratadine and terfenadine, which were 13.25$\pm$0.75 mm,7.5$\pm$ 1.02 mm (53% reduction, p<0.007),6.2$\pm$0.58 mm(43% reduction, p <0.01), and 8.4 $\pm$0.67 mm(37% reduction, p< 0.05), respectively, comparing with placebo. Loratadine and cetirizine were good antihistamines for clinical therapy for atopic dermatitis in dog.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.38 no.4
• /
• pp.401-408
• /
• 2009

PME88 (gliadin-combined) melon superoxide dismutase (SOD) is known to promote the production of the body‘s own natural antioxidants including superoxide dismutase, catalase and glutathione peroxidase. In this study, we investigated the inhibitory effects of PME88 melonSOD on the ultraviolet-induced photo-aging by the evolution of minimal erythemal dose (MED), erythema quotation and spectrocolorimetric measurements of erythema. The analysis of the evolution of the MED showed a significant increase 28 days after the daily taken of the PME88 melonSOD. The analysis of the erythema quotation showed that on D29, for the dose 1.25 MED, erythema intensity is significantly higher for placebo group than for PME88 melonSOD group. At doses 0.64 MED$_{D14}$, 0.80 MED$_{D14}$ and 1 MED$_{D14}$ the value of parameter $a^*$ (the most sensitive to the colour changes bound to the variations of blood flow. It permits to assess the evolution of erythema) is significantly higher for placebo group. No significant difference has been observed between groups (PME88 melonSOD and placebo) on the evolution of the number and consistency of feces after 4 weeks of treatment. No intolerance has been observed during the 4 weeks of treatment. These results mean that PME88 melonSOD as a dietary supplement could be useful to attenuate ultraviolet-induced skin photo-aging.

• Journal of Yeungnam Medical Science
• /
• v.1 no.1
• /
• pp.185-190
• /
• 1984

Toxic epidermal necrolysis is a reactive erythema of nonstaphylococcal origin characterized by a scalded appearance of the skin. The TEN is widely regarded as a variant of severe erythema multiforme because of its acute course, its freguent common cause, its freguent overlap with Stevens-Johnson disease, and its histologic identity. I present a case of TEN with severe mucosal involvement resembled Stevens-Johnson disease.

• Proceedings of the Korean Society of Veterinary Clinics Conference
• /
• 2009.04a
• /
• pp.242-242
• /
• 2009

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.15 no.2
• /
• pp.228-236
• /
• 2002

Persistent facial telangiectasia, erythema and flushing are the major cosmetic problems in patients with rosacea. However various therapeutic modalities for rosacea are not effective. Five patients who had a history of rosacea which poorly controlled by oral and topical medications, were given Herb-medication and Acupuncture treatment. The size of erythema and the number of papules had been gradually decreased and finally all the symptoms were gone except telangiectasia.

• The Korean Nurse
• /
• v.8 no.2 s.40
• /
• pp.30-31
• /
• 1969

• Herbal Formula Science
• /
• v.25 no.3
• /
• pp.337-347
• /
• 2017

Objectives : Atopic Dermatitis (AD) is chronic skin disease characterized by allergic hypersensitivity reactions. Samhwangsasim-tang Gamibang(SHSST) can treat skin disease by cooling down blood heat, clearing away congenital fever and detoxicating. This study was conducted to investigate the effects of SHSST on AD induced by oxazolone in mice. Methods : We investigated the effects of SHSST on skin tickness, skin lesions, erythema and melanin index, water content and histopathological changes in vivo. The effects on body weights and spleen body weight ratio were also investigated in mice with AD. Results : In our results, oral administration of SHSST ameliorated skin lesion such as flare, erythema, exudate and petechia and lowered skin thickness induced by oxazolone. In addition, SHSST lowered erythema index and elevated water content compared to AD control respectively. In the histopathological observation, oral administration of SHSST prevented epidermal hyperplasia and spongiotic changes which is a hallmark of skin inflammation respectively. Finally, SHSST did not affect spleen/body weight ratio. Conclusions : These data imply that SHSST can ameliorate skin lesion of AD such as flare, erythema, exudate and petechia, and be used to treat AD patients with relative safety.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.31 no.3 s.52
• /
• pp.279-283
• /
• 2005

The content of lipid or moisture and index of erythema or melanin on each facial part of 170 urban middle-aged women without dermic disease was measured by non-invasive method. This measurement intended to understand the skin condition on each facial part of middle-aged women, and to determine the correlation between objective measured values and subjective symptom of lipid content/moisture content. The results was summarized as follows. At each facial Part, the order of moisture content was eye rims, forehead, and cheek and that of lipid content was forehead, eye rims, and cheek. The erythema index was in the order oi forehead, cheek and eye rims and melanin index, in the order of eye rims, forehead and cheek. It turned out that the middle-aged women generally lacked lipid content rather than moisture one. The objective measured values of lipid content coincided with subjective symptom of lipid type. The lipid content, erythema index and melanin index showed correlation significantly.