• 한국주거학회논문집
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• 제26권4호
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• pp.83-94
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• 2015

Ernst May and the New Frankfurt Initiative are well known for the urban planning and the Housings in Frankfurt a. M. Their works tend to be underestimated because of some factors such as modest attitude toward modernism design vocabulary, short period that their programs lasts, and modification/recession of project in actual construction. So, This study aims to build up the relations related to Housing, such as situation of post World War I in German Society and Frankfurt, May's cognition on the working class, and realization of rationalization as a major tools of the modernity. Ernst May considered the working class with bipolar standpoint. Ernst May and His team considered working class and those families not only as object of relief but also as potential 'modern citizens' to be disciplined; he sympathize poor conditions of working class while discriminating them by their labor charge. Acceptance of Socially Disadvantaged group in construction were also proceeded in means of recession of cost. Even Ernst May and his team did not achieved the goals that they thought they could, their Siedlung and house designs articulated the sense of modernity, which presented in rationalization with highly practical manner. Those are realized in 3 directions; respectful considerations for existing traditional factors, application of extendable logics of physical/social hygiene, and reflection of issues with standardization and mass production.

• Asian-Australasian Journal of Animal Sciences
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• 제25권11호
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• pp.1521-1528
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• 2012

Previously identified QTL regions on BTA1 and BTA5 were investigated to validate the QTL regions and to identify candidate genes for growth and carcass traits in commercial cattle populations from the USA and Korea. Initially, a total of 8 polymorphic microsatellite (MS) markers in the BTA1 and 5 QTL regions were used for Chi-square tests to compare the frequencies of individual alleles between high and low phenotypic groups for the US (Michigan Cattleman's Association/Michigan State University; MCA/MSU) cattle. For a subsequent study, 24 candidate genes containing missense mutations and located within the QTL regions based on bovine genome sequence data were analyzed for genotyping in the two commercial cattle populations. Re-sequencing analyses confirmed 18 public missense SNPs and identified 9 new SNPs. Seventeen of these SNPs were used for genotyping of the MCA/MSU cattle (n = 98) and Korean native cattle (n = 323). On BTA1, UPK1B, HRG, and MAGEF1 polymorphisms residing between BM1312 and BMS4048 were significantly associated with growth and carcass traits in one or both of the MCA/MSU and Korean populations. On BTA5, ABCD2, IL22 and SNRPF polymorphisms residing between BL4 and BR2936 were associated with marbling and backfat traits in one or both of the MCA/MSU and Korean cattle populations. These results suggested that BTA 1 and 5 QTL regions may be segregating in both Korean Hanwoo and USA commercial cattle populations and DNA markers tested in this study may contribute to the identification of positional candidate genes for marker-assisted selection programs.

• 한국동물학회지
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• 제33권1호
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• pp.70-77
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• 1990

생쥐의 정자가 부정소에서 성숙하는 동안 Phosphatase 활성도의 변화를 알아보기 위하여 본 연구를 실시하였다. 효소의 활성도는 Ernst(1975)의 방법을 변용하여 측정하였으며 그 결과를 요약하면 다음과 같다. 부정소으 두부내 정자와 미부내 정자으 단백질 함량은 각각 59.1 $\pm$8.4(mg/10 9 sperm), 14.0$\pm$12.3(mg/10 9 sperm)으로 나타났다. 기본 반응액에서 나타난 두부내 정자의 효소 활성도를 100%로 할 때, 미부내 정자의 활성도는 ALPase가 29.2%, ALPase가 44.9% 그리고 ALPase가 53.8%였으며, 초음파로 정자를 분쇄하였을 경우에 ALPase는 16.5%, ALPase는 33.3% 그리고 ALPase는 38.7%였다. 따라서 미부내 정자의 phoshatase 활성도는 두부내 정자에 비하여 현저히 감소하였다. 그리고 부정소의 미부내 정자에서 K+ -dependent ALPase와 ALPase의 활성도는 두부내 정자에 비하여 유의하게 감소하였으며, 초음파로 정자를 분쇄하였을 때 $Ca^2$+ -dependent phoshatase의 활성도는 유의하게 증가하였다. 이상의 결과로 보아 생쥐의 정자가 부정소에서 성숙하는 동안 phoshatase의 활성도가 감소하는 것은 성숙과정에서 정자가 수정능력을 획득하는 데 어떤 중요한 역할을 할 것으로 사료된다.

• 한국IT서비스학회지
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• 제14권2호
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• pp.315-335
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• 2015

The New Way of Working (NWOW) is changing the world in which we work today. The principles of NWOW are based on freedom of time and place to work, and steering on output (results) instead of input (presence). As NWOW is a relatively new phenomenon, research on the effect of NWOW on knowledge sharing in organizations is scarce. In this research two multiple-case studies were performed to investigate the effect of the New Way of Working on knowledge. In the first study (A) different knowledge sharing scenarios were used at organizations that were in the process of implementing NWOW. This provided the opportunity to compare the sharing of knowledge between 'NWOW workers' and employees that still worked in the traditional way (non-NWOW workers). In total 216 scenario results were evaluated to determine differences in channel choice between the traditional and new work environment. For the second study (B) a Knowledge Sharing Framework was developed, based on the theories of Nonaka and Alavi & Leidner. This framework was used to determine the type of knowledge shared, e.g. tacit or explicit knowledge, in 84 situations. Additionally, to measure the level of NWOW adoption, a NWOW Analysis Monitor was used. The results show that NWOW workers use more different communication channels than traditional workers. When knowledge workers become more mobile, they will exchange knowledge less explicit (codified) and more tacit (personalized), use less face-to-face communication, but more video calls and e-mail. The adoption of the principles of NWOW seems to have a balancing effect on the knowledge that is shared in a tacit and explicit way, which in the view of Scheepers et al. is an effective knowledge sharing strategy. The research results show organizations need to realize that the New World of Working is affecting the way knowledge is shared. Missing out on this development may result in the loss of important knowledge and impact the operation of organizations.

• The Plant Pathology Journal
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• 제32권2호
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• pp.123-135
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• 2016

U.S. cotton production is suffering from the yield loss caused by the reniform nematode (RN), Rotylenchulus reniformis. Management of this devastating pest is of utmost importance because, no upland cotton cultivar exhibits adequate resistance to RN. Nine populations of RN from distinct regions in Alabama and one population from Mississippi were studied and thirteen morphometric features were measured on 20 male and 20 female nematodes from each population. Highly correlated variables (positive) in female and male RN morphometric parameters were observed for body length (L) and distance of vulva from the lip region (V) (r = 0.7) and tail length (TL) and c' (r = 0.8), respectively. The first and second principal components for the female and male populations showed distinct clustering into three groups. These results show pattern of sub-groups within the RN populations in Alabama. A one-way ANOVA on female and male RN populations showed significant differences ($p{\leq}0.05$) among the variables. Multiple sequence alignment (MSA) of 18S rRNA sequences (421) showed lengths of 653 bp. Sites within the aligned sequences were conserved (53%), parsimony-informative (17%), singletons (28%), and indels (2%), respectively. Neighbor-Joining analysis showed intra and inter-nematodal variations within the populations as clone sequences from different nematodes irrespective of the sex of nematode isolate clustered together. Morphologically, the three groups (I, II and III) could not be distinctly associated with the molecular data from the 18S rRNA sequences. The three groups may be identified as being non-geographically contiguous.

• Korean Journal of Radiology
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• 제19권6호
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• pp.1053-1065
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• 2018

Objective: To evaluate the clinical impact of using registration software for ablative margin assessment on pre-radiofrequency ablation (RFA) magnetic resonance imaging (MRI) and post-RFA computed tomography (CT) compared with the conventional side-by-side MR-CT visual comparison. Materials and Methods: In this Institutional Review Board-approved prospective study, 68 patients with 88 hepatocellulcar carcinomas (HCCs) who had undergone pre-RFA MRI were enrolled. Informed consent was obtained from all patients. Pre-RFA MRI and post-RFA CT images were analyzed to evaluate the presence of a sufficient safety margin (${\geq}3mm$) in two separate sessions using either side-by-side visual comparison or non-rigid registration software. Patients with an insufficient ablative margin on either one or both methods underwent additional treatment depending on the technical feasibility and patient's condition. Then, ablative margins were re-assessed using both methods. Local tumor progression (LTP) rates were compared between the sufficient and insufficient margin groups in each method. Results: The two methods showed 14.8% (13/88) discordance in estimating sufficient ablative margins. On registration software-assisted inspection, patients with insufficient ablative margins showed a significantly higher 5-year LTP rate than those with sufficient ablative margins (66.7% vs. 27.0%, p = 0.004). However, classification by visual inspection alone did not reveal a significant difference in 5-year LTP between the two groups (28.6% vs. 30.5%, p = 0.79). Conclusion: Registration software provided better ablative margin assessment than did visual inspection in patients with HCCs who had undergone pre-RFA MRI and post-RFA CT for prediction of LTP after RFA and may provide more precise risk stratification of those who are treated with RFA.

• 인지과학
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• 제20권1호
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• pp.79-107
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• 2009

공간, 시간적 환경정보를 함께 저장하는 일화기억(episodic memory)은 알츠하이머병에 의해 손상될 뿐만 아니라 일반 노화과정에서도 손상될 수 있다. 본 연구의 목적은 인지기능인 일화기억을 내적회상 기법을 사용하여 평가함으로써 초기 알츠하이머성 치매 환자의 일화기억을 분석하고 평가하는 것이다. 따라서 본 연구에서는 사진이나 동영상처럼 뇌에 투사되는 피시험자 자신의 과거를 직접 회상한 이미지(the mental image)를 분석하는 새로운 방법을 사용하였다. 초기 알츠하이머성 치매환자3명, 경도 우울증 환자 1명, 대조를 위한 건강한 노인 2명에게 검사 당일로부터 하루, 일주일, 한달 전 그리고 원과거(remote)에 있었던 일을 회상하게 하였다. 회상된 이미지 안에서의 감정상태, 이미지의 색, 사건 발생 순서 등의 중점을 두고 피시험자의 응답을 분석하였다. 순행성기억(anterograde memory) 손상을 관찰하고자 피시험자에 그들이 검사 당시 재현한 모든 이미지를 검사 다음날 다시 상기하도록 요구하였다. 3명의 환자군 모두 회상한 이미지들 사건 발생순서에 맞게 정리하는데 실패하였다. 이들은 대조군과 같은 수의 이미지를 회상해 내었지만, 색이 선명하지 않고 사진과 같은 정적인 이미지를 회상하였다. 이러한 결과는 초기 치매환자가 최근기억(recent memory)을 화상 하는데 일차적으로 손상이 있을 시사하며, 또한 의미기억의 양적인 손상보다 질적 손상이 먼저 발생함을 보여주었다.

• 철학연구
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• 제147권
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• pp.117-146
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• 2018

이 논문은 인공지능시대에도 종교는 가능한가, 오직 인간만이 종교신앙의 주체일 수 있는가, 인간의 마음을 탑재한 초지능기계들도 신앙의 주체일 수 있는가를 다룬다. 초지능기계들이 인간과 동일한 조건에서 신앙의 주체가 되려면, 인간의 고유한 특성인 감정, 의지, 자의식 등을 가질 수 있어야 한다. '특이점' 이후의 초지능기계들은 종교신앙의 주체를 넘어서서, 신과 같은 존재로서 인간과 자연과 세계를 지배하게 될 것이다. 이는 모라벡, 커즈와일, 하라리의 공통된 견해이다. 칸트가 구상한 '순수이성의 이념'과 '실천이성의 요청'으로서 신 개념은 제시 베링이 앞서 말한 것처럼 '간극의 신'처럼 보일 수 있다. 종교적 신앙 주체는 항상 도덕적인 선을 행하려고 부단하게 노력해야 하지만, 그런 노력 자체만으로는 완전선(完全善)에 도달할 수 없기 때문에 영혼불멸성을 요청하였다. 그러나 특이점을 넘어서 출현한 초지능기계가 지능폭발로 신적 지위를 가질 수 있다면, 인공지능로봇은 칸트적인 의미에서 종교적 수행을 불필요하게 여길 것이다. 에른스트 블로흐의 경우에는 초지능기계가 신적 존재라고 하더라도, 그것이 악신인가 선신인가를 비판적으로 물어야 한다. 칸트의 매트릭스에서는 선신일 수 있는 초지능기계가 블로흐의 매트릭스에서는 악신으로 추락할 수도 있다. 따라서 초지능기계-신이 우리를 유일한 종교신앙의 완성으로 이끌어 가는지, 인류와 지구촌의 몰락으로 내몰아갈 것인지를 부단하게 비판적으로 성찰해야 한다.