• 한국식품영양학회지
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• 제28권3호
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• pp.387-395
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• 2015

This study was conducted to verify the effects of Erigeron annuus powder on serum lipid levels of high-fat diet-induced mice from a nutritional viewpoint. Erigeron annuus powder has been used as a folk remedy since ancient times in Korea. There was no significant difference in the weight of the kidneys and spleens of the mice. The high-fat diet group had a significantly higher kidney weight compared to other groups (p<0.05). In the group of mice fed 20% Erigeron annuus powder with a high-fat diet, the concentration of serum LDL-cholesterol was high (p<0.05), whereas the concentration of triglyceride was remarkably lower compared to other groups (p<0.05). The group fed 10% Erigeron annuus with a high-fat diet had the lowest concentration of blood phospholipids (p<0.05) as well as the highest alkaline phosphatase and alanine aminotransferase levels in blood (p<0.05). There was no difference in blood insulin concentration. However, blood leptin concentration was significantly higher ($5.88{\pm}3.53ng/dL$) in mice fed a high-fat diet compared to other groups (p<0.05). Measurements of Erigeron annuus revealed that TPC, $ABTS^+$ radical scavenging activity of trolox, DPPH radical scavenging activity, and the measured value of FRAP were higher in the ethanol extract than in the water extract. Especially, the antioxidant activity effects were excellent for the $ABTS^+$ radical scavenging activities of trolox and FRAP values of Erigeron annuus. Therefore, Erigeron annuus powder showed antioxidant activity. Hence, Erigeron annuus powder drastically lessened triglyceride concentration in blood in high-fat diet-induced mice. Thus, the powder is considered to have utility in the food processing industry. Additional related experiments are ongoing.

• 한국응용과학기술학회지
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• 제33권4호
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• pp.717-725
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• 2016

본 연구는 개망초꽃 에센셜 오일의 항산화, 항균 및 항염 효능에 관하여 조사한 것이다. 개망초꽃 에센셜 오일은 용매추출법으로 추출하였다. 개망초꽃 에센셜 오일의 항산화 효능은 ABTS 라디칼 소거능과 DPPH 라디칼 소거 효능 측정으로 확인하였다. ABTS 라디칼 소거 효과는 $500{\mu}g/ml$ 농도에서 98.6%, DPPH 라디칼 소거는 48.3%로 좋은 효능을 나타내었다. 항균 활성은 S. aureus와 P. acnes, E. coli 균에 대하여 paper disc법과 최소저해농도(MIC)와 최소사멸농도(MBC)값을 측정하여 확인하였다. S. aureus 균주에 대해서는 MIC 값과 MBC 값이 모두 0.31 mg/mL 농도에서 우수한 억제 효과를 나타내었다. P. acnes 균에 대해서는 disc법에서 14 mm의 clear zone 형성과 MIC, MBC에서 각각 0.31 mg/mL, 0.63 mg/mL로 좋은 억제 효과를 보였다. 항염 활성에 관련하여 NO 억제 측정에서도 농도 의존적으로 NO의 생성을 억제시킴을 확인하였고, pro-inflammatory cytokine인 TNF-${\alpha}$, IL-6 역시 농도 의존적으로 억제하였다. 이러한 결과로부터 개망초꽃 에센셜오일은 항산화, 항균 및 항염 효능을 갖는 화장품 원료로서 개발 가능성이 있음을 시사한다.

• Applied Biological Chemistry
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• 제51권4호
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• pp.305-308
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• 2008

Seven compounds (1-7) were isolated from n-hexane and EtOAc-soluble fractions of the roots of Erigeron annuus by repeated silica gel column chromatography. They were identified as simiarenol (1), ${\beta}$-sitosterol (2), daidzein (3), apigenin (4), apigenin 7-O-${\beta}$-D-glucuronide (5), 3-hydroxy-pyran- 4-one (6), and ${\beta}$-sitosterol glucoside (7) on the basis of physical and spectroscopic data. Compounds 1 and 3 were isolated for the first time from the Erigeron species.

• Applied Biological Chemistry
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• 제47권4호
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• pp.422-425
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• 2004

개망초의 꽃을 80% MeOH 용액으로 추출하고, 추출물을 EtOAc, n-BuOH 및 물로 분배, 추출하였다. 이 중 EtOAc 분획을 silica gel, octadecylsilica gel(ODS) column chromatography 및 high performance liquid chromatography(HPLC)로 정제하여 3종의 화합물을 분리하였다. 각 화합물의 화학구조는 NMR, MS 및 IR 등의 스펙트럼 데이터를 해석하여, ${\alpha}-amyrenone(1),\;{\alpha}-amyrin(2)$ 및 ${\beta}-amyrin(3)$으로 동정하였다. 이들 3종의 triterpenoid는 개망초에서는 처음 분리되었다.

• 한국식품영양과학회지
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• 제34권6호
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• pp.857-861
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• 2005

개망초를 새로운 기능성 식품의 재료로 사용하기 위하여 각 부위별 화학성분을 조사하였다. 개망초의 꽃, 잎, 줄기 및 뿌리의 가용성 무질소물의 함량은 각각 53.15, 55.79, 36.71 및 $42.61\%$로 각각 나타났다. 조섬유의 함량은 줄기와 뿌리에서 비슷하게 나타났으며, 보다 잎에서 낮은 함량을 나타내었다. 개망초에 함유되어 있는 주요 무기성분으로는 $Na(19.55\~33.78\;mg/100\;g),\;K(49.95\~$89.80\;mg/100\;g)$및 $Ca(25.39\~116.40\;mg/100\;g)$으로 나타났으며, 개망초의 각 부위별 Ca의 함량은 꽃, 줄기 및 뿌리보다 잎에서 가장 높은 함량을 나타내었다. 개망초에 함유되어 있는 주요 유리당으로는 $sucrose(0.12\~l.37\%),\;glucose(0.68\~1.08\%$) 및 $fructose(0.56\~1.66\%)$로 각각 나타났다. 개망초의 부위별 총 아미노산 함량은 꽃 2,509.74 mg/100 g, 잎 2,630.95 mg/100 g, 줄기 889.54 mg/100 g 및 뿌리 1,201.41 mg/100 g으로 나타났으며, 꽃과 잎에 가장 많이 함유되어 있는 주요 아미노산으로는 glutamic acid, tyrosine 및 proline로 나타났다. 또한 줄기 에서는 lysine, glutamic acid, aspartic acid로 나타났고, 뿌리 에서는 lysine glutamic acid 및 proline로 나타났다. 개망초에 함유되어 있는 주요 유기산으로는 succinic $acid(4.78\~19.72\;mg/100\;g)$, tartaric $acid(3.90\~6.91\;mg/100\;g)$ 및 citric $acid(1.79\~6.60\;mg/100\;g)$로 나타났다. 개망초에는 총 9종의 지방산이 함유되어 있었고,주요 지방산으로는 myristic acid$(18.05\~20.18\%)$, oleic acid(18.50$\~$32.91$\%$) 및 linoleic acid$(18.02\~29.87\%)$로 나타났으며, 총 플라보노이드와 총 페놀성분은 꽃과 잎에서 다른 부위보다 높게 나타났다.

• Journal of Applied Biological Chemistry
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• 제50권3호
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• pp.160-163
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• 2007

Two flavonoids (1 and 2) and one phenolic acid (3) obtained from Erigeron annuus have recently been shown to have potent antioxidant activities. Aim of this study was to investigate the inhibitory effects of these components on $interferon-{\gamma}$ and lipopolysaccharide-induced nitric oxide productions in the mouse pheritoneal macrophage. Compounds 2 and 3 showed marked inhibitory activities against inducible nitric oxide synthase (iNOS) on the lipopolysaccharide and $interferon-{\gamma}-stimulated$ mouse pheritoneal macrophages without cytotoxicity. Therefore, these results suggest that the compounds could be effective anti-inflammatory agents as nitric oxide inhibitors in vivo.

• Biotechnology and Bioprocess Engineering:BBE
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• 제11권1호
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• pp.13-18
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• 2006

The antioxidant activity of the extract of Erigeron annuus was assessed by means of two different in vitro tests: bleaching of the stable 1,1-diphenyl-2-picrylhydrazyl radical (DPPH test) and the scavenging of authentic peroxynitrite in company with peroxynitrite generation from 3-morpholinosydnonimine (SIN-1). In both tests, the 85% aq. MeOH and n-BuOH soluble fractions of the crude extract showed a significant scavenging effect on peroxynitrite and DPPH radical in comparison to L-ascorbic acid. And bioassay-guided fractionation of the n-BuOH soluble fraction led to the isolation of three compounds: Apigenin (1), quercetin-3-O-glucoside (2), and caffeic acid (3). The structures of the isolated compounds were elucidated on the basis of their spectroscopic data and their antioxidant activities were measured by determining their capacity to scavenge peroxynitrite and the DPPH radical.

• 환경영향평가
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• 제15권6호
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• pp.407-415
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• 2006

This study carried out submerged area due to Dam construction in the near future. It includes species classification of plant, survey of community structure, examination of pollutant load and assessment of water quality impact. The vascular plants of this area are listed 224 taxa; 64 families, 168 genera, 193 species, 30 varieties and 1 form. This study area is classified into total 21 communities, most community was consist of grass vegetation. Among the communities, Erigeron annuus ($869,286m^2$, 22%) community was dominant and Erigeron annuus-Avena fatua comminity (16%) was subdominant until May, and then Erigeron canadensis community occupied most area to $1,774,985m^2$ (32%) from May to July. For the evaluation of water quality impact due to submerged macrophyte, nutrient release test was conducted both dead body macrophyte and living body macrophyte. The results of release test show that T-N is not released at dead body macrophyte, but it is released at living body macrophyte, especially living body Artemisia priceps var. orientalis shows 1.436mgN/g. At release test of dead body macrophyte, T-P release rate of Erigeron annuus shows 0.500mgP/g at the top of them and it also shows 0.436mgP/g at Erigeron annuus of living body macrophyte. T-N load of submerged macrophyte shows 0.76% by comparison of total load on watershed and T-P load of that shows 3.61%. In case of removal macrophyte for reduction of pollutant load in submerged area, T-N load of submerged macrophyte changes from 0.76% to 0.15% by comparison of total load on watershed and T-P load of that changes from 3.61% to 0.72%.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 추계국제학술대회
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• pp.47-47
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• 2020

In this study, we aimed to study carnation italian ringspot virus (CIRV) in Erigeron annuus (L.) Pers. in Bonghwa County, Korea. The collected samples showed mosaic and malformation symptoms. To identify the virus species, we performed high-throughput sequencing, reverse transcription polymerase chain reaction, and cloning. The virus was confirmed to be an unreported species, and therefore we performed genome sequencing of the samples. The complete genome was 4,746 nucleotides in length. The CIRV contained five open reading frames (ORFs), and it showed the typical features of members of the genus Tombusvirus. Phylogenetic analyses revealed that ClRV isolates had the highest nucleotide identities with the CZ isolate (95.89%) from Korea. In recent years, these viruses have sporadically been reported in floral scent and medicinal plants. This research found the first natural host infected with CIRV, and provides baseline information to determine the correlation between weeds and crops.

• The Korean Journal of Ecology
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• 제15권2호
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• pp.103-115
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• 1992

This dissertation, which has been prepared in the region of cheju(33o31'N, 126o32'E) from may,1987 to appril, 1989, is to elucidate the dominant characteristics of early stages in secondary succession, by examining the life history of erigeron annuus for the seeding depth of a seed was dependent upon the degree of shading. That is, on the area of ocm,the more tense the shading was, the more germination percentage was increased, while, in the case of 1.5cm, it was somewhat increased, when shading bwcame ess and less tense. The rosette of e. annuus, through its relative light intensity was decreased by shading, up to 5% of natural light, showed some strong shade tolerance, which had no difficulty in matter production. The species diversity of mixed-species community was the highest in the middle of April, the lowest in the last of may. The dominance index was the highest in the late may, the lowest in the middle of April. Toward the end of may, the occupation rate of dominance species was the highest. There was a neutral relationship between intraspecific and interspecific, owing to the differentiation of its niche, temporally and spatially. Productive structure of the community revealed a narrow leaf type which was concentratively distributed in the mid part of community height. The relative light intensity of community ground surface was 6.1%, the leaf inclination 60o,the extinction coefficient(k) 0.4, biomass of community 1,045.6 g.d.w./m2,T/Rratio 9.3, C/Frate 7.0 and sumgermanition, shade toarance and community characteristics on erigeron annuus l.in chejumed leaf area index 3.88. through the various life cycles o e.annuus, we can say that it decreases mortality of seeding caused by some stress and disturbance, for germination lasts for a long time at any opportunity available, and it promotes population growth. The strong shade tolerance of a rosette and the variableness of a life from differentiate the niche between intraspecific and interspecific within the community, and avoid the direct competition between them, thus poromoting community growth.