• 대한두경부종양학회지
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• 제26권2호
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• pp.243-246
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• 2010

Purpose : Eosinophilic granuloma is a rare benign tumor that is characterized histologically by the presence of destructive granulomas containing numerous Langerhans, cells. The most common presentation of eosinophilic granuloma is a painful, immobile scalp mass in the frontal and parietal bones occurring predominantly in children and adolescents or young adults. We report a representative case of eosinophilic granuloma. Methods : A 16-year-old woman complained of an enlarging fixed scalp mass without pain and tenderness which measured $3{\times}4.5cm$ at the frontal area, which had been found incidentally 2 months before. Plain skull x-ray showed a punched-out bone lesion. Computed tomography and magnetic resonance imaging showed a non-enhancing osteolytic lesion. The tumor and surrounding bony edges were completely removed via a bicoronal approach. The bony defect was reconstructed with bone cement. Results : The tumor was involved frontal bone and dura mater. We confirmed the tumor by the documentation of Birbeck's granules by electron microscopy. There is no evidence of local recurrence during postoperative 1.5 years. Conclusion : The present case shows the characteristic feature of frontal bone involvment of the eosinophilic granuloma. The prognosis of eosinophilic granuloma depend on age at diagnosis and number of bones involved. We consider that best choice of treatment for eosinophilic granuloma is surgical excision.

• Imaging Science in Dentistry
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• 제43권2호
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• pp.117-122
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• 2013

Eosinophilic granuloma is a common expression of Langerhans cell histiocytosis and corresponds with typical bone lesions. The radiographic appearance of eosinophilic granuloma in the jaw is variable and not specific. It may resemble periodontitis, radicular cyst, or malignancies. The purpose of this report is to describe the characteristic radiographic features of eosinophilic granuloma of a 39-year-old male. The lesion in the anterior mandible was first diagnosed as radicular cyst because the radiographic findings were ovoid radiolucent lesion with well-defined border. However, careful interpretation revealed a non-corticated border and floating tooth appearance that were the characteristic radiographic features for the differential diagnosis. Early clinical signs of eosinophilic granuloma can occur in the jaw and a bony destructive lesion might be mistaken for periodontitis or an odontogenic cystic lesion; therefore, careful interpretation of radiographs should be emphasized.

• Tuberculosis and Respiratory Diseases
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• 제40권4호
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• pp.424-430
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• 1993

저자들은 개흉 폐생검으로 종격동 임파절과 폐를 동시에 침범한 호산구성 육아종을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제19권2호
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• pp.325-330
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• 1986

Eosinophilic granuloma is one of the histiocytosis X. It may occur in any bone and tissues, but the one originated from the sternum was rarely reported. Recently, we experienced an eosinophilic granuloma at the manubrium sterni, associated with diabetes insipidus, which was surgically resected. Although intranasal spray of DDAVP has been used for the control of diabetes insipidus, the bony lesion was remitted. With the brief review of the literatures, we report the case.

• 대한수의학회지
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• 제51권1호
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• pp.69-72
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• 2011

Eosinophilic granuloma is a common hypersensitive inflammatory skin disease in cats, and rare in dogs and horses. The skin biopsies of 5 years old female Cocker spaniel and 2 years old female mixed dog had the clinical signs of skin nodules with alopecia were submitted for diagnosis. Solitary skin nodules and papillary nodules were presented on the left external ear and back of Cocker spaniel and on the external ear of mixed dog, respectively. Histopathologically, epidermis of skin showed mild to severe hyperplasia with multifocal ulceration. Small to large irregular, brightly eosinophilic foci with degenerating eosinophils and homogeneous degenerated collagens were existed in the dermis of both ear and back skin. Typical 'flame figures', a mixture of degenerated collagen and degranulated eosinophils, were observed in both cases. Based on the histopathologic findings and special staining characters, 2 cases were diagnosed as canine eosinophilic granuloma. This is the first report for the eosinophilic granuloma of dogs in Korea.

• 대한치과의사협회지
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• 제5권1호
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• pp.71-74
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• 1964

The authors have observed a case of eosinophilic granuloma which occurred in 10 years old girl 1.The lesion which occurred swelling and facial disfigurement , was located in the right side of ramus mandible, but toothache and loosening of tooth was absent. 2. Roentgenograph showed bean-sized monocystic radiolucent shadow in mandible border.3. Microscopically,few hemorrhagic araas were existed, and numerous eosinophilic leukocytes eosinophilic myelocyteswith inflammatory cells were infiltrated.

• Imaging Science in Dentistry
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• 제38권1호
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• pp.63-67
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• 2008

The present study reports a case of eosinophilic granuloma of the mandibular condyle. Eosinophilic granulomas on the mandibular condyle are very rare, but there are several common clinical and radiographic presentations. The clinical presentations involve swelling on preauricular area, limitation of opening, TMJ pain, etc. The radiographic presentations involve radiolucent lytic condylar lesion with or without pathologic fracture. Sometimes new bone formations are observed. The purpose of the article is to add new cases to the literatures.

• Journal of Korean Neurosurgical Society
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• 제43권6호
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• pp.304-306
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• 2008

Langerhans' cell histiocytosis (LCH) is a rare immunologic disorder characterized by histiocyte proliferation in multiple organ systems. Eosinophilic granuloma, a benign bone lesion, represents a focal form of LCH. We experienced a case of Langerhans' cell histiocytosis in a patient who presented with intracranial epidural hematoma and cyst on the midline of the frontal skull. A 10-year-old boy presented with a rapidly growing large scalp mass on the midline frontal area after mild head trauma. The scalp mass was painless and immobile. Plain skull x-ray showed a punched-out bone lesion. Computed tomography and magnetic resonance imaging showed a non-enhancing osteolytic lesion presenting with an epidural hematoma and cyst on the midline of the frontal skull. The lesion of the skull was completely resected and the patient's recovery was uneventful. The acute presentation of a solitary eosinophilic granuloma of skull with an epidural hematoma has been described in only five cases in the literature and we report the first case of LCH presenting as an intracranial epidural hematoma on frontal area.

• Tuberculosis and Respiratory Diseases
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• 제41권2호
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• pp.152-157
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• 1994

본 저자들은 양측성으로 반복되는 자연기흉 소견을 보인 21세 남자 환자에서BAL은 시행하여 조직구내 Birbeck granule을 찾음으로써 확진할 수 있었던 골 침범을 동반한 폐 조직구증 1예를 문헌 고찰과 함께 보고하는 바이다.

• 대한골관절종양학회지
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• 제12권2호
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• pp.171-175
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• 2006

척추에서의 호산구 육아종은 흔하지 않으며, 특히 경추 및 후방 신경궁에서의 발생은 드물다. 또한 호산구 육아종은 자기 공명 영상을 포함한 방사선학적 검사상 추체의 붕괴, 척추경의 소실 및 척추 주변 연부 조직의 종물 형성 등의 소견을 보이므로 다른 악성 골종양이나 전이성 종양 또는 결핵성 척추염 등과 감별을 요한다. 저자들은 각각 제 4 경추, 제 7 경추의 후방 신경궁, 그리고 제 4 경추체에서 발생한 호산구 육아종에 대하여 수술적 치료 후 완치를 보인 3례를 경험하였기에 문헌 고찰과 함께 보고하고자 한다.