• Environmental Analysis Health and Toxicology
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• v.30
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• pp.14.1-14.7
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• 2015

Objectives Cigarette smoking is associated with carcinogenesis owing to the mutagenic and genotoxic effects of cigarette smoke. The aim of this study was to evaluate the mutagenic and genotoxic effects of Korean cigarettes using in vitro assays. Methods We selected 2 types of cigarettes (TL and TW) as benchmark Korean cigarettes for this study, because they represent the greatest level of nicotine and tar contents among Korean cigarettes. Mutagenic potency was expressed as the number of revertants per ${\mu}g$ of cigarette smoke condensate (CSC) total particulate matter whereas genotoxic potency was expressed as a concentration-dependent induction factor. The CSC was prepared by the International Organization for Standardization 3308 smoking method. CHO-K1 cells were used in vitro micronucleus (MNvit) and comet assays. Two strains of Salmonella typhimurium (Salmonella enterica subsp. enterica ; TA98 and TA1537) were employed in Ames tests. Results All CSCs showed mutagenicity in the TA98 and TA1537 strains. In addition, DNA damage and micronuclei formation were observed in the comet and MNvit assays owing to CSC exposure. The CSC from the 3R4F Kentucky reference (3R4F) cigarette produced the most severe mutagenic and genotoxic potencies, followed by the CSC from the TL cigarette, whereas the CSC from the TW cigarette produced the least severe mutagenic and genotoxic potencies. Conclusions The results of this study suggest that the mutagenic and genotoxic potencies of the TL and TW cigarettes were weaker than those of the 3R4F cigarette. Further study on standardized concepts of toxic equivalents for cigarettes needs to be conducted for more extensive use of in vitro tests.

• Proceedings of the Korean Society of Toxicology Conference
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• 2003.10b
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• pp.96-102
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• 2003

Benzene is an environmental pollutant that is present in mineral oil, natural gas, coal tar, gasoline, motor vehicle emissions, and tobacco smoke. The importance of benzene resides in the fact that it can induce hematotoxicity and leukemia in human and mice. However, the underlying mechanism of benzene hematotoxicity and leukemogenicity is still not fully understood.(omitted)

• Journal of the Korean Wood Science and Technology
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• v.43 no.6
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• pp.768-776
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• 2015

This study was performed to understand combustion properties four major Indonesian wood species such as Albizia, Gmelina, Mangium and Mindi were investigated by cone-calorimeter for better utilization of theses wood species. Heat release rate (HRR), total heat release (TSR), specific mass loss rate (SMLR), effective heat of combustion (EHC), time to ignition (TTI), flame time (FT), specific extinction area (SEA), smoke production rate (SPR) and CO compound production rate were measured. HRR, THR and FT were proportional to the density of woods. Albizia showed the highest HRR, while Mindi had the lowest HRR. For SPR, Albizia showed the highest value due to its higher SEA. On the other hand, Mindi had the lowest SPR due to a lower SEA value. The highest smoke emission was for Albizia at the beginning of combustion. After 300 seconds, smoke emission of Gmleina and Mangium was increased greatly. Mangium and Mindi showed the highest total carbon dioxide emission. Expecially, Gmelina released the highest carbon monoxide during the combustion period and presented three times higher $CO/CO_2$ ratio than those of other species due to incomplete combustion.

• Journal of the Korean Society of Tobacco Science
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• v.19 no.2
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• pp.162-169
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• 1997

An important and somewhat under-emphasized issue in assessing the risk potentially associated with exposure to ETS is the reliability and objectivity of the methods used to measure the actual level of exposure. Objectivity of the science is crucial in this context since this topic tends to elicit strong social, emotional and political responses among the general public and the scientific community alike. This mini-review compares the strengths and limitations of various methods used in determining ETS exposure in scientific investigations. Methods reviewed include: questionnaire, area monitoring, bio-monitoring, and personal monitoring. In particular, results of several recent studies (conducted in the United States, Europe, and the Far East) using personal monitors in combination with questionnaire and bio-monitoring, which contribute to a more reliable, objective and realistic estimates of a person's actual exposure to 575, are discussed.

• Journal of Environmental Health Sciences
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• v.28 no.3
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• pp.26-33
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• 2002

Adolescents exposed chronically to tobaccotobacco smoke have been found to have reduced pulmonary function as well as an increased risk of lung cancer and a serious heart disease. Consequently, reducing exposure to tobacco smoke is an important public health goal. This study was conducted to develope the exact evaluation method of student smoker or heavy exposure from ETS, and the change on smoking behavior and attitude after a stop-smoking program. From the study, we concluded that the cotinine concentrations in saliva from students indicate exactly whether they are smoker or not. Also, it was found that the more and exact informations from both the cotinine analysis and the questionnaire were obtained than from only the questionnaires. The non-smokers had more positive effects on the changes of cog-nitions, behaviors and attitude about passive-smoking after a stop-smoking program than the smokers. The results of this study show that through both the accurate determination of cotinine in saliva and the questionnaires, the smoking status and the tobacco education effectiveness can be predicted.

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2000.11a
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• pp.43-44
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• 2000

흡연 당사자의 직접흡연이 이와 관련한 발병률과 사망률의 주요 원인이 되어 왔다는 것은 여러 연구조사자료에 보고되어 왔다. 그러나 최근 들어 담배연기에 대한 비흡연자의 비자의적인 노출 즉, 환경담배연기(Environmental Tobacco Smoke, 이하 ETS)로 인한 보건학적 위해성에 대한 논란이 제기되면서 간접흡연은 새로운 사회문제로 대두되고 있다(Surgeon General, 1986). 1986년에 미국 National Research Council은 미국 내에서 연간 3000명에 달하는 폐암의 발생이 ETS에 대한 노출에서 기인한다고 발표한 바 있으며(NRC, 1986), 이를 근거로 1990년대 초에 미국 EPA와 NIOSH에서는 세계최초로 ETS를 인체발암성물질로 규정한 바 있다(NIOSH, 1991; USEPA, 1992). (중략)

• Environmental Analysis Health and Toxicology
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• v.18 no.4
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• pp.237-242
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• 2003

Single cell gel electrophoresis (SCGE) was used to the experiment with the variation on the amount of smoking and low dose radiation exposure to find how much the Lymphocyte DNA was damaged, and especially for whom smoke a lot(about 20 or more than 20 cigarettes a day) it was found to be highly damaged. While, the damage of 'not more than 20 cigarettes a day' was found to be not so much significant as like for whom smoke about or more than 20 cigarettes a day And, according to the different amount of the radiation exposure, the Lymphocyte DNA was found to be considerably damaged for 0-13m Sv (P<0.01), it was not able to prove the relationship between the DNA damage and the radiation exposure.

• Fire Science and Engineering
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• v.31 no.1
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• pp.50-57
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• 2017

The present article discusses the response characteristics of smoke detector chamber due to dust and wind velocity. Although situations have improved in terms of early sensing of fires as the smoke detectors are applied indoors, studies tend to place insufficient focus on the side effects and malfunction that can be caused by diversified life dust produced indoors and environmental requirements, etc. Therefore, in the present study, 4 types of photoelectric smoke detectors with different forms and structures of smoke chamber were selected as the experimental objects, and dust test was conducted with fly ash, talcum powder and fiber dust as experiment samples to study indoor applicability of the smoke detectors in terms of their response to diversified dust and wind velocity. Also, to observe response characteristics due to pollution level inside the smoke chamber, wind velocity for dust test were set additionally at 0.25 m/s, 0.5 m/s, and 1.0 m/s. Based to the experimental results, fly ash, talcum powder, and fiber dust (black hair powder) were found to be suitable at the dust test reference wind velocity conditions of 0.25 m/s for both operation test and non-operation test after dust application. On the other hand, under the harsh wind velocity conditions of 0.5 m/s and 1.0 m/s, malfunction of unwanted alarm was observed in non-operation tests in the case of fly ash and talcum powder, and non-operation was confirmed to occur in the case of fiber dust as the alarm failed to operate normally in operation tests.

• Journal of the Korean Society of Tobacco Science
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• v.35 no.1
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• pp.47-55
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• 2013

• Proceedings of the Korean Society of Tobacco Science Conference
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• 2003.05a
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• pp.35-35
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• 2003