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The Influence of Smoking and Low Dose Radiation Exposure to the Damage of the Lymphocyte DNA  

Shin Heuyn-Kil (한국원자력병원 임상의학연구실)
Kim Yun-Joo (한동대학교 생명과학연구소)
Kwon Eun-Hye (한동대학교 생명과학연구소)
Yook Jin-Young (한동대학교 생명과학연구소)
Choi Soo-Yong (한국원자력병원 임상의학연구실)
Publication Information
Environmental Analysis Health and Toxicology / v.18, no.4, 2003 , pp. 237-242 More about this Journal
Abstract
Single cell gel electrophoresis (SCGE) was used to the experiment with the variation on the amount of smoking and low dose radiation exposure to find how much the Lymphocyte DNA was damaged, and especially for whom smoke a lot(about 20 or more than 20 cigarettes a day) it was found to be highly damaged. While, the damage of 'not more than 20 cigarettes a day' was found to be not so much significant as like for whom smoke about or more than 20 cigarettes a day And, according to the different amount of the radiation exposure, the Lymphocyte DNA was found to be considerably damaged for 0-13m Sv (P<0.01), it was not able to prove the relationship between the DNA damage and the radiation exposure.
Keywords
single cell gel electrophoresis; DNA damage; lymphocyte DNA; low dose radiation; smoking;
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