• Title/Summary/Keyword: Environmental Aging

Search Result 739, Processing Time 0.026 seconds

Skin Hydration Effect of Brasenia schreberi Mucilage Polysaccharide Extract (순채 점액질 다당체 추출물의 피부 보습 효과 연구)

  • Ahn, Seyeon;Gil, Soyeon;Kwon, Ohsun;Chang, Yunhee;Jin, Mu Hyun
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.43 no.3
    • /
    • pp.223-230
    • /
    • 2017
  • In this study, we evaluated the skin moisturizing effect of Brasenia schreberi (B. schreberi) mucilage polysaccharide on human skin and in vitro and the potent cosmetic ingredient for skin. To protect skin from various environmental stresses and aging, we should increase moisture content of skin and prevent water loss. We have found that polysaccharides extracted from mucilage of B. schreberi improved the roughness of skin with its lubricating behavior. In vitro, the expression of transglutaminase 1 (TGM1) gene, which plays a role in cross-linking the skin barrier, was increased when the keratinocytes were treated with B. schreberi polysaccharides. In addition, the expression of hyaluronan synthase 3 (HAS3) gene, an enzyme that synthesizes water-binding matrix hyaluronic acid, aquaporin 3 (AQP3), which regulates the movement of water and glycerol were also increased. In addition, an experiment to evaluate its potential as a cosmetic ingredient has shown anti-inflammatory and collagen synthesis-promoting effects. As a result, the mucilaginous polysaccharide from natural products which has not existed before, showed moisturizing effect, anti-inflammation and collagen synthesis-promoting effects for skin protection and hydration.

Bioinformatics Analysis of Gene Expression Regulation by Transposable Elements in Dementia Patients (치매환자에서 transposable elements에 의한 유전자 발현조절의 생물정보 분석)

  • Kim, Dae-Soo;Huh, Jae-Won;Ha, Hong-Seok;Kim, Tae-Hong;Jo, Un-Jong;Kim, Heui-Soo
    • Journal of Life Science
    • /
    • v.16 no.7 s.80
    • /
    • pp.1188-1194
    • /
    • 2006
  • Dementia is a progressive disease of increasing the dysfunction of intellectual and physical ability. In the aging society, many families are suffering from the caring the patients who are diagnosed with dementia. However, dementia is a complex disease affected by the genetic and environmental agents. In the present study, we investigated the transposable elements in relation to dementia. From the analysis of dementia EST (expressed sequence tag) sequences, we found dementia candidate genes, and analyzed expression profiles and repeat elements using bioinformatics tools. This analysis showed that 98 genes were affected in their mRNA sequences by transposable elements expression. Their expressions were affected by the integration of different transposable elements (SINE, LINE, LTR, DNA) during the primate evolution. We believe that our work will be of significant interest to genome scientists, and may help them gain insight into implication of transposable elements expression in dementia.

A Study on the Qualification System for Raising Engineers of Maintenance for Apartment Houses - Based on the Qualification System of the United States - (공동주택 유지관리전문인력 육성을 위한 자격체계에 관한 연구 - 미국의 자격체계를 중심으로 -)

  • Park, Sang Hoon
    • Journal of the Korea institute for structural maintenance and inspection
    • /
    • v.15 no.1
    • /
    • pp.169-179
    • /
    • 2011
  • Korea owns vast amount of apartment houses no less than those of world prominent countries, but did not pay enough efforts to maintain existing apartment houses and develop policies to reuse them due to growth driven policy of housing supply like construction of new houses. Korea constructed tremendous amount of houses in short period through government led forced house supplying policy, and resulted in excess houses such that present house supply rate happened to be reaching 110%. However, recently there are growing demand of change in housing policy due to social environmental changes like low birth rate and aging of society etc and nationals' demand for improvement of residential quality. When such social changes are demanded and 80% of apartment houses in Korea are less than 20 years old, renovations and remodeling of apartment houses are anticipated to emerge as important matter. In particular, the apartment houses in Seoul and the 1st generation new cities like Bundang and Ilsan etc have passed considerable period of time after construction and require safety measure, it is quite impending to raise engineers for the maintenance of existing apartment houses. Therefore, in this paper, direction for the raising of maintenance engineers in Korea was proposed through analysis of relevant qualification system for the apartment houses maintenance engineers in the U.S.

Preliminary Study on the Paleoenvironment Reconstruction using a Bivalve from Sangmori Shell Mound (상모리패총에서 산출되는 이매패류 패각을 이용한 고환경 복원 예비연구)

  • Kim, Jeong-Suk;Woo, Kyung-Sik;Hong, Wan;Kang, Chang-Hwa
    • The Korean Journal of Quaternary Research
    • /
    • v.24 no.2
    • /
    • pp.35-48
    • /
    • 2010
  • The purpose of this study is to investigate paleoenvironmental conditions of the shallow sea around Jeju Island during the Late Holocene using geochemical contents of the bivalve (Glycymeris albolineata) collected from the Sangmori Shell Mound. The bivalve shell used shows the archaeological age of 2,300 yr BP. Stable carbon and oxygen isotope compositions show that growth rates decreased with aging. Coeval trends of both isotope compositions can be observed: heavier values during winters and lighter values summers except for their young and old growth stages. The seasonality of bivalve shell appear to reflect seasonal variations of paleotemperature as well as paleosalinity. Especially China Coastal Water with low salinity was transported into the southern Jeju Strait from Changjiang River during summer periods. Heavier carbon isotope values during winter indicate higher productivity, and this is supported by high density of phytoplanktons and higher chlorophyll contents during winter time. For accurate interpretation, monitoring of present-day conditions of shallow marine water as well as additional geochemical analysis of the same Recent bivalve may be necessary.

  • PDF

Design of Communication Board for Communication Network of Nuclear Safety Class Control Equipment (원자력 안전등급 제어기기의 통신망을 위한 통신보드 설계)

  • Lee, Dongil;Ryoo, Kwangki
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.19 no.1
    • /
    • pp.185-191
    • /
    • 2015
  • This paper suggest the safety class communication board in order to design the safety network of the nuclear safety class controller. The reactor protection system use the digitized networks because from analog system to digital system. The communication board shall be provided to pass the required performance and test of the safety class in the digital network used in the nuclear safety class. Communication protocol is composed of physical layer(PHY), data link layer(MAC: Medium Access Control), the application layer in the OSI 7 layer only. The data link layer data package for the cyber security has changed. CRC32 were used for data quality and the using one way communication, not requests and not responses for receiving data, does not affect the nuclear safety system. It has been designed in accordance with requirements, design, verification and procedure for the approving the nuclear safety class. For hardware verification such as electromagnetic test, aging test, inspection, burn-in test, seismic test and environmental test in was performed. FPGA firmware to verify compliance with the life-cycle of IEEE 1074 was performed by the component testing and integration testing.

Relationship of Riboflavin and Niacin with Cardiovascular Disease (심혈관 질환과 리보플라빈 및 나이아신과의 상관성 연구)

  • Ahn, Ji Yeong;Kim, In Sik;Lee, Ji-Sook
    • Korean Journal of Clinical Laboratory Science
    • /
    • v.51 no.4
    • /
    • pp.484-494
    • /
    • 2019
  • Cardiovascular disease is caused by different factors. These factors include innateness factors such as aging, biological factors such as high blood pressure, and environmental factors such as stress. This study examined the factors associated with cardiovascular disease and the ways to reduce its prevalence by analyzing the data within the Korean National Health and Nutrition Examination Reports from 2013 to 2017, and particularly the survey and examination data for people over 50 years old. The study population was divided into two groups: members of the first group consumed riboflavin and niacin at the recommended rate while those in the second group did not. Riboflavin intake was correlated with hypertension, hyperglycemia, and a low HDL-cholesterol level, whereas niacin intake was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level. The combination of niacin and riboflavin intakes was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level (P<0.05). The combined intake of the recommended levels of riboflavin and niacin reduced the average physiological factor abnormality rate to 80%. Taken together, the beneficial effects of riboflavin and niacin can reduce the prevalence of cardiovascular disease.

Development of an UV Distribution Model for the Design of a Submerged UV Disinfection Reactor and Its Application (침지형 자외선 살균조 설계를 위한 자외선 분포 모델의 개발 및 적용)

  • Park, Changyeun;Kim, Sunghong;Choi, Younggyun
    • KSCE Journal of Civil and Environmental Engineering Research
    • /
    • v.41 no.5
    • /
    • pp.505-512
    • /
    • 2021
  • A 3D model was developed to calculate the UV intensity of a submerged-type UV disinfection reactor. Numerical experiments were conducted by inputting the design factors of an open channel-type disinfection reactor and a pipe-type disinfection reactor that were installed in an actual sewage treatment plant. The following data were obtained: The average UV intensity of the installed open channel-type reactor and pipe-type reactor was 7.87 mW/cm2 and 13.09 mW/cm2, respectively; the UV dose reflecting the UV irradiation time and taking into account attenuation effects such as mixing imbalance, lamp aging, temperature, and fouling, was expected to be 21.1 mJ/cm2 and 24.8 mJ/cm2, respectively, and these values are 5 % and 24 % higher than the target UV dose of 20 mJ/cm2, respectively. By using the UV3D model, the optimal lamp position, which maximizes the average UV intensity without changing the size of the disinfection reactor or lamp output power, can be found. In this case, by only adjusting the lamp position, the average UV intensity can be increased by 0.9 % for the open channel-type and 0.5 % for the pipe-type, respectively. A better average UV intensity can be obtained by model simulation. By adjusting the horizontal and vertical ratio of the open channel-type reactor and by moving the lamp position, the average UV intensity can be increased by 7.4 % more than the present case.

Deep learning algorithm of concrete spalling detection using focal loss and data augmentation (Focal loss와 데이터 증강 기법을 이용한 콘크리트 박락 탐지 심층 신경망 알고리즘)

  • Shim, Seungbo;Choi, Sang-Il;Kong, Suk-Min;Lee, Seong-Won
    • Journal of Korean Tunnelling and Underground Space Association
    • /
    • v.23 no.4
    • /
    • pp.253-263
    • /
    • 2021
  • Concrete structures are damaged by aging and external environmental factors. This type of damage is to appear in the form of cracks, to proceed in the form of spalling. Such concrete damage can act as the main cause of reducing the original design bearing capacity of the structure, and negatively affect the stability of the structure. If such damage continues, it may lead to a safety accident in the future, thus proper repair and reinforcement are required. To this end, an accurate and objective condition inspection of the structure must be performed, and for this inspection, a sensor technology capable of detecting damage area is required. For this reason, we propose a deep learning-based image processing algorithm that can detect spalling. To develop this, 298 spalling images were obtained, of which 253 images were used for training, and the remaining 45 images were used for testing. In addition, an improved loss function and data augmentation technique were applied to improve the detection performance. As a result, the detection performance of concrete spalling showed a mean intersection over union of 80.19%. In conclusion, we developed an algorithm to detect concrete spalling through a deep learning-based image processing technique, with an improved loss function and data augmentation technique. This technology is expected to be utilized for accurate inspection and diagnosis of structures in the future.

A Study on the Design of Data Collection System for Growing Environment of Crops (작물 근권부 생장 환경 Data 수집 시스템 설계에 관한 연구)

  • Lee, Ki-Young;Jeong, Jin-Hyoung;Kim, Su-Hwan;Lim, Chang-Mok;Lee, Sang-Sik
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
    • /
    • v.11 no.6
    • /
    • pp.764-771
    • /
    • 2018
  • Domestic and foreign agricultural environments nowadays are undergoing various changes such as aging of agricultural population, increase of earned population, rapid climate change, diversification of agricultural product distribution structure, depletion of water resources and limited cultivation area. In order to respond to various environmental changes in recent agriculture, practical use of Smart Greenhouse to easily record, store and manage crop production information such as crop growing information, growth environment and agriculture work log, Interest is growing. In this paper, we propose a system that collects the situation information necessary for growth such as temperature, humidity, solar radiation, CO2 concentration, and monitor the collected data, which can be measured in the rhizosphere of the crop. We have developed a system that collects data such as temperature, humidity, radiation, and growth environment data, which are measured by data obtained from the rhizosphere measuring section of a growing crop and measured by a sensor, and transmitted to a wireless communication gateway of 400 MHz. We developed the integrated SW that can monitor the rhythm environment data and visualize the data by using cloud based data. We can monitor by graph format and data format for visualization of data. The existing smart farm managed crops and facilities using only the data within the farm, and this study suggested the most efficient growth environment by collecting and analyzing the weather and growth environment of the farms nationwide.

Implicit and Explicit Attitudes of Korean Children towards Older Adults (한국 어린이의 노인에 대한 태도: 명시적 태도와 암묵적 태도 차이를 중심으로)

  • Han, Gyoung-hae;Seok, Minae;MaloneBeach, E.E.
    • 한국노년학
    • /
    • v.37 no.2
    • /
    • pp.475-496
    • /
    • 2017
  • Increasing evidence shows that ageist attitudes towards older adults develop quite early in childhood in Western culture, yet, empirical research on this topic in Korea is lacking. It has been argued that as Korea has become more youth oriented, negative views of aging have emerged and Korean children are increasingly exposured to negative stereotypes of older adults. Nuclearization of family structure and consequent reduction of intergenerational interaction is considered to be another important factor. The purpose of this study is to find out whether Korean children have ageist attitudes. Acknowledging the possibility that children tend to report in socially appropriate ways to the explicit measures of ageism, we included implicit measures of ageism. Data was collected from 570 fourth to sixth grade elementary school children selected by quota sampling. The current study used Child-Age Implicit Association Test and two other explicit measurements. The original versions were modified to be culturally applicable to the Korean context. Results indicated that when measured explicitly, children do not report preferring younger person than older person. However when measured implicitly, it was found that children at this young age already reveal negative biases toward the elderly. Contrast to the fact that the level of explicit ageism is significantly different by demographic characteristics of children, no statistical difference in the level of implicit ageism is detected. Based on the results, implications are discussed.