• 제목/요약/키워드: Engineering technology

검색결과 93,615건 처리시간 0.093초

Decellularized Matrices for the Treatment of Tissue Defects: from Matrix Origin to Immunological Mechanisms

  • Xinyue Wang;Jiqiang Guo;Qing Yu;Luyao Zhao;Xiang Gao;Li Wang;Meiling Wen;Junrong Yan;Meiwen An;Yang Liu
    • Biomolecules & Therapeutics
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    • 제32권5호
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    • pp.509-522
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    • 2024

  • Decellularized matrix transplantation has emerged as a promising therapeutic approach for repairing tissue defects, with numerous studies assessing its safety and efficacy in both animal models and clinical settings. The host immune response elicited by decellularized matrix grafts of natural biological origin plays a crucial role in determining the success of tissue repair, influenced by matrix heterogeneity and the inflammatory microenvironment of the wound. However, the specific immunologic mechanisms underlying the interaction between decellularized matrix grafts and the host immune system remain elusive. This article reviews the sources of decellularized matrices, available decellularization techniques, and residual immunogenic components. It focuses on the host immune response following decellularized matrix transplantation, with emphasis on the key mechanisms of Toll-like receptor, T-cell receptor, and TGF-β/SMAD signaling in the stages of post-transplantation immunorecognition, immunomodulation, and tissue repair, respectively. Furthermore, it highlights the innovative roles of TLR10 and miR-29a-3p in improving transplantation outcomes. An in-depth understanding of the molecular mechanisms underlying the host immune response after decellularized matrix transplantation provides new directions for the repair of tissue defects.

  • https://doi.org/10.4062/biomolther.2024.050 인용 PDF

하이브리드(HEV) 구동 모터용 모터-코어 금형 개발에 관한 실험적 연구 (An Experimental Study on the Motor-Core Die Development of HEV Traction Motor)

  • 홍경일;김세환;최계광;정현석;임세종
    • Design & Manufacturing
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    • 제9권2호
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    • pp.34-37
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    • 2015

  • The HEV Traction Motor Core manufacturing technology is a core component of HEV Traction Motor Core (Iron Core) is a key technology for the manufacture of eco-friendly automotive industry is essential for the competitiveness of the country must obtain the technology. In this study, the HEV Motor Core of the Rotor manufacturing technology, the Stator manufacturing technology applied to Press Lamination Die and Core(Iron Core) was developed and the results are discussed.

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RODMRP를 위한 진보된 추론 연결 망 구현 (A study on the Advanced Inference Routing NETwork scheme for RODMRP)

  • 김순국;지삼현;두경민;이범재;김영삼;이강환
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2008년도 하계종합학술대회
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    • pp.313-314
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    • 2008

  • Ad hoc network is a multi-hop wireless network formed with non-infrastructure. The fact that limited resource could support the network of robust, simple framework and energy conserving etc. In this paper, we propose a new ad hoc multicast routing protocol for based on the ontology scheme called inference network. Ontology knowledge-based is one of the structure of context-aware.

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Parasitic Capacitive Housing Effects in a Multi-Lamps Backlight

  • Kim, Sang-Beom;Cho, Mee-Ryoung;Hong, Seong-Moon;Lee, Yong-Kon;Lee, Sang-Heok;Lee, Ji-Hoon;Lee, Joo-Young;Hong, Jin-Woo;Yang, Dong-Wook;Lee, Dea-Heung;Kim, Bong-Soo;Kang, June-Gill;Cho, Guang-Sup
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2003년도 International Meeting on Information Display
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    • pp.639-641
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    • 2003

  • The parasitic capacitance between the high voltage electrodes and the backlight housing causes lowering lamp current, electric power leakage, and leading to lower brightness and efficiency in a multi-lamps backlight. In this study a new center balance swing operation method is introduced to be minimizing those housing effects.

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