• Title/Summary/Keyword: Engineering process

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A Pilot Study for the Remote Monitoring of IMRT Using a Head and Neck Phantom (원격 품질 보증 시스템을 사용한 세기변조 방사선치료의 예비 모니터링 결과)

  • Han, Young-Yih;Shin, Eun-Hyuk;Lim, Chun-Il;Kang, Se-Kwon;Park, Sung-Ho;Lah, Jeong-Eun;Suh, Tae-Suk;Yoon, Myong-Geun;Lee, Se-Byeong;Ju, Sang-Gyu;Ahn, Yong-Chan
    • Radiation Oncology Journal
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    • v.25 no.4
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    • pp.249-260
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    • 2007
  • Purpose: In order to enhance the quality of IMRT as employed in Korea, we developed a remote monitoring system. The feasibility of the system was evaluated by conducting a pilot study. Materials and Methods: The remote monitoring system consisted of a head and neck phantom and a user manual. The phantom contains a target and three OARs (organs at risk) that can be detected on CT images. TLD capsules were inserted at the center of the target and at the OARs. Two film slits for GafchromicEBT film were located on the axial and saggital planes. The user manual contained an IMRT planning guide and instructions for IMRT planning and the delivery process. After the manual and phantom were sent to four institutions, IMRT was planed and delivered. Predicted doses were compared with measured doses. Dose distribution along the two straight lines that intersected at the center of the axial film was measured and compared with the profiles predicted by the plan. Results: The measurements at the target agreed with the predicted dose within a 3% deviation. Doses at the OARs that represented the thyroid glands showed larger deviations (minimum 3.3% and maximum 19.8%). The deviation at OARs that represented the spiral cord was $0.7{\sim}1.4%$. The percentage of dose distributions that showed more than a 5% of deviation on the lines was $7{\sim}27%$ and $7{\sim}14%$ along the horizontal and vertical lines, respectively. Conculsion: Remote monitoring of IMRT using the developed system was feasible. With remote monitoring, the deviation at the target is expected to be small while the deviation at the OARs can be very large. Therefore, a method that is able to investigate the cause of a large deviation needs to be developed. In addition, a more clinically relevant measure for the two-dimensional dose comparison and pass/fail criteria need to be further developed.

Degradation Kinetic and Mechanism of Methyl Tert-butyl Ether (MTBE) by the Modified Photo-Fenton Reaction (Modified Photo-Fenton Reaction을 이용한 Methyl Tert-butyl Ether (MTBE)의 분해 Kinetic 및 메커니즘 규명에 관한 연구)

  • Kim, Min-Kyoung;Kong, Sung-Ho
    • Journal of Soil and Groundwater Environment
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    • v.11 no.6
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    • pp.69-75
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    • 2006
  • Improper disposal of petroleum and spills from underground storage tanks have created large areas with highly toxic contamination of the soil and groundwater. Methyl tert-butyl ether (MTBE) is widely used as a fuel additive because of its advantageous properties of increasing the octane value and reducing carbon monoxide and hydrocarbon exhausts. However, MTBE is categorized as a possible human carcinogen. This research investigated the Modified Photo-Fenton system which is based on the Modified Fenton reaction and UV light irradiation. The Modified Fenton reaction is effective for MTBE degradation near a neutral pH, using the ferric ion complex composed of a ferric ion and environmentally friendly organic chelating agents. This research was intended to treat high concentrations of MTBE; thus, 1,000 mg/L MTBE was chosen. The objectives of this research are to find the optimal reaction conditions and to elucidate the kinetic and mechanism of MTBE degradation by the Modified Photo-Fenton reaction. Based on the results of experiments, citrate was chosen among eight chelating agents as the candidate for the Modified Photo-Fenton reaction because it has a relatively higher final pH and MTBE removal efficiency than the others, and it has a relatively low toxicity and is rapidly biodegradable. MTBE degradation was found to follow pseudo-first-order kinetics. Under the optimum conditions, [$Fe^{3+}$] : [Citrate] = 1 mM: 4 mM, 3% $H_2O_2$, 17.4 kWh/L UV dose, and initial pH 6.0, the 1000 ppm MTBE was degraded by 86.75% within 6 hours and 99.99% within 16 hours. The final pH value was 6.02. The degradation mechanism of MTBE by the Modified Photo-Fenton Reaction included two diverse pathways and tert-butyl formate (TBF) was identified to be the major degradation intermediate. Attributed to the high solubility, stability, and reactivity of the ferric-citrate complexes in the near neutral condition, this Modified Photo-Fenton reaction is a promising treatment process for high concentrations of MTBE under or near a neutral pH.

A feasibility of coagulation as post-treatment of the anaerobic fluidized bed reactor (AFBR) treating domestic wastewater (도시하수 처리 혐기성 유동상 반응조의 후속공정으로서 화학응집의 가능성 평가)

  • Yang, Seung Yong;Bae, Jae Ho
    • Journal of Korean Society of Water and Wastewater
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    • v.28 no.6
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    • pp.623-634
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    • 2014
  • This study examined a feasibility of coagulation as post-treatment to remove sulfide and phosphorus for the effluent of anaerobic fluidized bed reactor (AFBR) treating domestic wastewater. Removal efficiencies of sulfide, phosphorus and COD by coagulation were not affected by pH in the range of 5.9 to 7.2. Alkalinity requirement could be estimated by the amount of $Fe^{3+}$ to form $Fe(OH)_{3(S)}$ and to remove sulfide and phosphorus. At coagulant aid dosage of 2 mg/L, anionic polymer showed best results regarding size and settleability of flocs. Sulfide removal for the AFBR effluent at the $Fe^{3+}/S^{2-}$ ratio of 0.64, close to the theoretical value of 0.67 found with a synthetic wastewater, was only 75.2%. One of the reasons for this high $Fe^{3+}/S^{2-}$ ratio requirement is that the AFBR effluent contains sulfide, phosphorus, hydroxide and bicarbonate which can react with $Fe^{3+}$ competitively. Concentrations of sulfide and phosphorous reduced to below 0.1 and 0.5 mg/L, respectively, at the $Fe^{3+}/S^{2-}$ ratio of 2.0. Average effluent COD of 80 mg/L, mostly soluble COD, was obtained at the dosage 50 mg $Fe^{3+}/L$ ($Fe^{3+}/S^{2-}$ ratio of 2.0) with corresponding COD removal of 55%. For better removal of COD, soluble COD removal at the AFBR should be enhanced. Coagulation with $Fe^{3+}$ removed sulfide, phosphorus and COD simultaneously in the AFBR effluent, and thus could be an alternative process for the conventional wastewater treatment processes where relatively high quality effluent is not required.

Development of Heat Exchanger for Fermentation Heat Utilization from Waste Woody Biomass (목질계 폐바이오메스의 발효열이용 열교환기의 개발)

  • Cho, Nam-Seok;Choi, Tae-Ho;Kim, Hong-Eun;Lee, Suk-Ho;Lee, Chung-Koo
    • Journal of the Korean Wood Science and Technology
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    • v.37 no.1
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    • pp.94-104
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    • 2009
  • It is urgently required to develop the production of fermentation-heat energy from the waste agricultural and forest biomass and its effective heat exchanging system for the supply of warm water to rural households and greenhouses. In this study 3 helical-type and 1 plate-type heat exchangers using 3 different waste biomasses [e.g. hardwood (HW) sawdust (100%), softwood (SW) sawdust : HW sawdust (50 : 50) and HW sawdust : grass (90 : 10)] were applied in order to find out the best heat recovery system. The heat exchanger was basically considered to improve the overall heat recovery efficiency, to minimize heat loss and to simplify manufacturing, assembling and breaking up the fermenting beds. The helical-type heat exchanger (HX-H3) installed in fermenting bed of HW sawdust : grass (90 : 10) showed relatively higher temperature profiles, in particular mid- and upper-parts than lower and surface parts during 45-day fermentation process. The maximum temperature was ranged from $40^{\circ}C$ to $65^{\circ}C$ with average $60^{\circ}C$. The water temperature of tank outlet was ranged to $33{\sim}48^{\circ}C$ during whole measuring periods. By the way plate-type one (HX-P) installed in same biomass compositional fermenting bed showed $64.5{\sim}76.5^{\circ}C$ at center part, and $43{\sim}56^{\circ}C$ and $42{\sim}58^{\circ}C$, water tank and tank outlet temperatures, respectively, during 100 day measurement. It could be concluded that the plate-type heat exchanger (HX-P) provides not only the effective heating for the rural households and greenhouses, but also having the best heat recovery performance, easy manufacturing, assembling and breaking up the systems.

Hydraulic Assessment about Correlation of Fluvial Movement and River Bed Form on the Narrow Pass of Channel (하천 협소부에서 하상 이동성과 형태와의 상관성에 관한 하도수리학적 평가)

  • Choi, Ho-Kyun;Kim, Won-Il;Lee, Sam-Hee;Ahn, Won-Sik
    • Journal of Korea Water Resources Association
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    • v.42 no.2
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    • pp.141-148
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    • 2009
  • Each river in each country has peculiar channel characteristics at every section. Korea consists of mountains at the rate of 70%. Due to this, the sections that display unique channel form are scattered. One of the typical features is the narrow pass of channel section that presents in the process of the generation of alluvial channel and deformation channel. Around as this narrow pass of channel, it often comes to be regular flood disaster section. Regardless of this situation, investigations and plans that reflect channel characteristics at the narrow pass of channel have been wholly wanting until now. In accordance with this, we have investigated and analysed hydraulic significance and channel form of the narrow pass of channel in Seonsan in this study. The study has found real minute classification of sediment phenomenon at river bed of low flow channel on investigation section which is sand-bed river, but it was vaguely difficult to conclude that classification of sediment arises from explicit natural force. We were able to assume that the phenomenon comes from gentle bed slope, supply of river bed materials which is nearly uniformity. However, classification of sediment would come from collecting an aggregate rather than natural force. And we found that compound cross section conversion has been developing dramatically with channel form of movable bed section referring to movement which was active before at drainage district of the narrow pass of channel. With this, we could find the phenomenon that river width of low flow channel diminished largely. This kind of situation implies that it may cause compound section weighting, flood dimension decreasing, revetment at low flow channel or the local scour at bottom of levee when extraordinary flood occurs.

Real-Time RT-PCR for Validation of Reovirus Type 3 Safety During the Manufacture of Mammalian Cell Culture-Derived Biopharmaceuticals (세포배양 유래 생물의약품 생산 공정에서 Reovirus Type 3 안전성 검증을 위한 Real-Time RT-PCR)

  • Lee, Dong-Hyuck;Jeong, Hyo-Sun;Kim, Tae-Eun;Oh, Seon-Hwan;Lee, Jung-Suk;Kim, In-Seop
    • Korean Journal of Microbiology
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    • v.44 no.3
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    • pp.228-236
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    • 2008
  • Validation of viral safety is essential in ensuring the safety of mammalian cell culture-derived biopharmaceuticals, because numerous adventitious viruses have been contaminated during the manufacture of the products. Mammalian cells are highly susceptible to Reovirus type 3 (Reo-3), and there are several reports of Reo-3 contamination during the manufacture of biopharmaceuticals. In order to establish the validation system for the Reo-3 safety, a real-time RT-PCR method was developed for quantitative detection of Reo-3 in cell lines, raw materials, manufacturing processes, and final products as well as Reo-3 clearance validation. Specific primers for amplification of Reo-3 RNA was selected, and Reo-3 RNA was quantified by use of SYBR Green I. The sensitivity of the assay was calculated to be $3.2{\times}10^0\;TCID_{50}/ml$. The real-time RT-PCR method was proven to be reproducible and very specific to Reo-3. The established real-time RT-PCR assay was successfully applied to the validation of Chinese hamster ovary (CHO) cell artificially infected with Reo-3. Reo-3 RNA could be quantified in CHO cell as well as culture supernatant. When the real-time RT-PCR assay was applied to the validation of virus removal during a virus filtration process, the result was similar to that of virus infectivity assay. Therefore, it was concluded that this rapid, specific, sensitive, and robust assay could replace infectivity assay for detection and clearance validation of Reo-3.

Anti-corrosion properties for cross section of Mg films on galvalume steel coated by PVD process (PVD법에 의해 Mg 코팅된 갈바륨 도금강판의 단면부 내식특성)

  • Park, Jae-Hyeok;Kim, Sun-Ho;Park, Gi-Dong;Jeong, Jae-In;Yang, Ji-Hun;Lee, Gyeong-Hwang;Lee, Myeong-Hun
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2018.06a
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    • pp.65-65
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    • 2018
  • 갈바륨 도금강판은 알루미늄의 우수한 차폐 특성과 내열성, 열 반사성을 가지며 아연의 희생방식 특성을 겸비하여 동일 부착량의 용융 아연도금 및 알루미늄 도금강판에 비해 우수한 내식성을 나타낸다고 알려져 있다. 또한 이것은 표면이 미려하고 경제성이 높아 건자재 용도로 현재까지도 세계적으로 널리 이용되고 있다. 여기서 지칭하는 바륨 도금강판(galvalume steel)은 아연과 알루미늄 도금강판의 장점을 접목하기 위해 55 Al-43.4 Zn-1.6 Si (wt.%)로 구성되어 개발된 3원계 성분의 합금도금강판이다. 한편, 최근에는 강재의 내식성을 향상시키기 위한 다양한 연구 결과에 의해 Zn-Al-Mg의 3원계 합금도금강판도 개발되어 사용되고 있다. 이것은 기존의 아연도금 강판 보다 10배 정도의 우수한 내식성을 나타내는 것으로 보고되고 있다. 특히, 이것은 도금된 평판부의 내식성은 물론 절단된 도금 단면부의 내식성도 매우 우수하다고 알려져 있다. 그러나 상기한 갈바륨 도금강판의 경우에는 도금된 표면부에 비해 단면부의 내식성이 상대적으로 취약한 것으로 알려져 있다. 따라서 본 연구에서는 갈바륨 도금강판의 내식성을 종합적으로 향상시키기 위하여 이 갈바륨 도금강판 상에 PVD 스퍼터링법에 의해 Mg 코팅막의 제작을 시도하였다. 여기서 Mg 코팅막은 후처리 된 갈바륨 도금강판 상에 Ar 공정압력 2 및 20 mTorr 조건 중 1.5 및 $3{\mu}m$ 두께로 제작하였다. 또한 제작한 코팅막에 대해서는 모폴로지 관찰(SEM) 및 결정구조 분석(XRD)을 하였고, 분극측정, 염수분무 시험(SST) 및 복합부식 시험(CCT)에 의해 표면 및 단면부의 내식성평가를 수행하였다. 또한 여기서는 염수분무 및 복합부식 시험 후의 시험편도 채취 하여 표면 및 단면부위에 대한 원소조성 분석(EPMA)과 결정구조 분석(XRD)을 실시하였다. 이상의 실험 결과에 의하면, 본 실험에서 제작한 Mg 코팅막은 그 두께가 두꺼울수록 표면 Mg 결정립의 크기가 증가하였고, 그 부식속도가 증가하는 경향을 나타내었다. 또한 여기서는 공정압력이 높은 조건에서 제작한 막일수록 Mg(002)면 피크 강도가 감소하고 Mg(101)면 피크의 배향성이 증가하였다. 그때 그 막의 내식성은 향상되는 경향을 나타내었다. 그리고 종합적으로 염수분무 및 복합부식 시험 결과에 의하면 Mg이 코팅된 갈바륨 도금강판은 기존 갈바륨 도금강판 보다 내식성이 현저히 향상되었다. 특히, 단면부 내식성의 경우에는 기존 대비 5배 이상 향상되는 경향을 나타내었다. 여기서 단면부 내식특성 분석을 위한 EPMA 원소조성 분석 결과에 의거하면, 부식 초기에는 마그네슘의 부식생성물에 의해 단면부가 치밀하게 보호되고 있음을 확인할 수 있었다. 그 이후에는 부식이 지속적으로 진행됨에 따라 갈바륨 도금층에서 용출된 알루미늄 및 아연 성분이 마그네슘과 함께 치밀한 부식생성물을 형성하여 단면부를 차폐함에 따라 단면부의 내식성이 크게 향상된 것으로 생각된다. 이러한 부식생성물의 결정구조 분석 결과에 따르면, 염수분무와 복합부식 시험에서는 공통적으로 MgO, $Mg(OH)_2$ 이외에도 Simonkolleite상 등이 형성되었다. 또한 건-습 반복 부식시험인 복합부식시험 후에는 $Mg_5(CO_3)_4(OH)_24H_2O$(Hydromagnesite)상 등이 형성됨을 확인할 수 있었다. 즉, 본 실험에서 후처리된 갈바륨 도금강판 상에 제작한 마그네슘 코팅막의 경우에는 상기와 같은 다양한 부식반응에 의해 표면 및 단면부에 형성된 Mg계 부식생성물과 $Zn_5(OH)_8Cl_2H_2O$(Simonkolleite)상에 의해서 표면은 물론 단면부 내식성이 크게 향상된 것으로 사료된다.

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Sediment Particulate Motions Over a Ripple Under Different Wave Amplitude Conditions (파랑에 의한 해저 사련 위에서의 유사입자의 거동 특성)

  • Chang, Yeon S.;Ahn, Kyungmo;Hwang, Jin H.;Park, Young-Gyu
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.25 no.6
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    • pp.374-385
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    • 2013
  • Sediment particle motions have been numerically simulated over a sinusoidal ripple. Turbulent boundary layer flows are generated by Large Eddy Simulation, and the sediment particle motions are simulated using Lagrangian particle tracking method. Two unsteady flow conditions are used in the experiment by employing two different wave amplitudes while keeping other conditions such as wave period same. As expected, the amount of suspended sediment particles is clearly dependent on the wave amplitude as it is increasing with increasing flow intensity. However, it is also observed that the pattern of suspension may be different as well due to the only different condition caused by wave amplitude. Specially, the time of maximum sediment suspension within the wave period is not coincident between the two cases because sediment suspension is strongly affected by the existence of turbulent eddies that are formed at different times over the ripple between the two cases as well. The role of these turbulent eddies on sediment suspension is important as it is also confirmed in previous researches. However, it is also found the time of these eddies' formation may also dependent on the wave amplitude over rippled beds. Therefore, it has been proved that various flow as well as geometric conditions under waves has to be considered in order to have better understanding on the sediment suspension process over ripples. In addition, it is found that high turbulent energy and strong upward flow velocities occur during the time of eddy formation, which also supports high suspension rate at these time steps. The results indicate that the relationship between the structure of flows and bedforms has to be carefully examined in studying sediment suspension at coastal regions.

Analysis and Performance Evaluation of Pattern Condensing Techniques used in Representative Pattern Mining (대표 패턴 마이닝에 활용되는 패턴 압축 기법들에 대한 분석 및 성능 평가)

  • Lee, Gang-In;Yun, Un-Il
    • Journal of Internet Computing and Services
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    • v.16 no.2
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    • pp.77-83
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    • 2015
  • Frequent pattern mining, which is one of the major areas actively studied in data mining, is a method for extracting useful pattern information hidden from large data sets or databases. Moreover, frequent pattern mining approaches have been actively employed in a variety of application fields because the results obtained from them can allow us to analyze various, important characteristics within databases more easily and automatically. However, traditional frequent pattern mining methods, which simply extract all of the possible frequent patterns such that each of their support values is not smaller than a user-given minimum support threshold, have the following problems. First, traditional approaches have to generate a numerous number of patterns according to the features of a given database and the degree of threshold settings, and the number can also increase in geometrical progression. In addition, such works also cause waste of runtime and memory resources. Furthermore, the pattern results excessively generated from the methods also lead to troubles of pattern analysis for the mining results. In order to solve such issues of previous traditional frequent pattern mining approaches, the concept of representative pattern mining and its various related works have been proposed. In contrast to the traditional ones that find all the possible frequent patterns from databases, representative pattern mining approaches selectively extract a smaller number of patterns that represent general frequent patterns. In this paper, we describe details and characteristics of pattern condensing techniques that consider the maximality or closure property of generated frequent patterns, and conduct comparison and analysis for the techniques. Given a frequent pattern, satisfying the maximality for the pattern signifies that all of the possible super sets of the pattern must have smaller support values than a user-specific minimum support threshold; meanwhile, satisfying the closure property for the pattern means that there is no superset of which the support is equal to that of the pattern with respect to all the possible super sets. By mining maximal frequent patterns or closed frequent ones, we can achieve effective pattern compression and also perform mining operations with much smaller time and space resources. In addition, compressed patterns can be converted into the original frequent pattern forms again if necessary; especially, the closed frequent pattern notation has the ability to convert representative patterns into the original ones again without any information loss. That is, we can obtain a complete set of original frequent patterns from closed frequent ones. Although the maximal frequent pattern notation does not guarantee a complete recovery rate in the process of pattern conversion, it has an advantage that can extract a smaller number of representative patterns more quickly compared to the closed frequent pattern notation. In this paper, we show the performance results and characteristics of the aforementioned techniques in terms of pattern generation, runtime, and memory usage by conducting performance evaluation with respect to various real data sets collected from the real world. For more exact comparison, we also employ the algorithms implementing these techniques on the same platform and Implementation level.

Improvement of Energy Efficiency of Plants Factory by Arranging Air Circulation Fan and Air Flow Control Based on CFD (CFD 기반의 순환 팬 배치 및 유속조절에 의한 식물공장의 에너지 효율 향상)

  • Moon, Seung-Mi;Kwon, Sook-Youn;Lim, Jae-Hyun
    • Journal of Internet Computing and Services
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    • v.16 no.1
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    • pp.57-65
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    • 2015
  • As information technology fusion is accelerated, the researches to improve the quality and productivity of crops inside a plant factory actively progress. Advanced growth environment management technology that can provide thermal environment and air flow suited to the growth of crops and considering the characteristics inside a facility is necessary to maximize productivity inside a plant factory. Currently running plant factories are designed to rely on experience or personal judgment; hence, design and operation technology specific to plant factories are not established, inherently producing problems such as uneven crop production due to the deviation of temperature and air flow and additional increases in energy consumption after prolonged cultivation. The optimization process has to be set up in advance for the arrangement of air flow devices and operation technology using computational fluid dynamics (CFD) during the design stage of a facility for plant factories to resolve the problems. In this study, the optimum arrangement and air flow of air circulation fans were investigated to save energy while minimizing temperature deviation at each point inside a plant factory using CFD. The condition for simulation was categorized into a total of 12 types according to installation location, quantity, and air flow changes in air circulation fans. Also, the variables of boundary conditions for simulation were set in the same level. The analysis results for each case showed that an average temperature of 296.33K matching with a set temperature and average air flow velocity of 0.51m/s suiting plant growth were well-maintained under Case 4 condition wherein two sets of air circulation fans were installed at the upper part of plant cultivation beds. Further, control of air circulation fan set under Case D yielded the most excellent results from Case D-3 conditions wherein air velocity at the outlet was adjusted to 2.9m/s.