• Title/Summary/Keyword: Energy distribution

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The Tissue Distribution of Nesfatin-1/NUCB2 in Mouse

  • Kim, Jinhee;Chung, Yiwa;Kim, Heejeong;Im, Eunji;Lee, Hyojin;Yang, Hyunwon
    • Development and Reproduction
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    • v.18 no.4
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    • pp.301-309
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    • 2014
  • Nesfatin-1, an anorexic nucleobindin-2 (NUCB2)-derived hypothalamic peptide, controls appetite and energy metabolism. Recent studies show that nesfatin-1/NUCB2 is expressed not only in the brain but also in gastric and adipose tissues. Thus, we investigated the distributions of nesfatin-1/NUCB2 in various tissues of male and female mice by real-time PCR, western blotting, and immunohistochemical staining. Real-time PCR analyses showed that NUCB2 mRNA was predominantly expressed in the pituitary and at lower levels in the hypothalamus, spleen, thymus, heart, liver, and muscle of both male and female mice. Expression was much higher in reproductive organs, such as the testis, epididymis, ovary, and uterus, than in the hypothalamus. Western blot analysis of the nesfatin-1 protein level showed similar results to the real-time PCR analyses in both male and female mice. These results suggest that nesfatin-1/NUCB2 have widespread physiological effects in endocrine and non-endocrine organs. In addition, immunohistochemical staining revealed that nesfatin-1 was localized in interstitial cells, including Leydig cells and in the columnar epithelium of the epididymis. Nesfatin-1 was also expressed in theca cells and interstitial cells in the ovary and in epithelial cells of the endometrium and uterine glands in the uterus. These results suggest that nesfatin-1 is a novel potent regulator of steroidogenesis and gonadal function in male and female reproductive organs. Further studies are required to elucidate the functions of nesfatin-1 in various organs of male and female mice.

A Study on the Stress Analysis and Parameters of Bucking in Spherical Shell (반 구형 각의 좌굴현상에 대한 응력해석 및 영향인자에 관한 연구)

  • Kim, Yeong-Su;An, Du-Seong
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.21 no.2
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    • pp.142-150
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    • 1985
  • In this paper, stress distribution were given in consideration of bending effects in hemi-spherical shell and a modified equation of buckling load was represented with implicating the effects of plastic deformations and shape parameters. Especially, the distributions of shell near it's vertex were analyzed numerically, according to several cases of loading. For the sake of more good estimation of plastic dissipating energy, we used the yield-line method from plate theory. The modified criterion of bucking, P super(*) sub(cr), that was suggested in this study, was applied to SUS 302 stain-less steel hemi-spherical shell which had it's Poisson's ratio and Young's modulus with 0.33 and 19700 kg/mm$^2$. From some experiments and comparisons with other results, 재 suggested the critical buckling-load-equation with P super(*) sub(cr)=2E super(*).(t super(2)/a super(2)).{3(1-ν super(*2)} and computed the buckling initiation load with this equation. Because these result from modified criterion have more coincidence than previous one, we prospect this equation can be magnified it's utilities to the other materials.

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Current Status of Policy and Market for Biodiesel in Korea (바이오디젤 보급을 위한 정책 및 시장 현황)

  • Kim, Seung-Soo;Kim, Ki-Ho;Shin, Seong-Cheol;Yim, Eui-Soon
    • Applied Chemistry for Engineering
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    • v.18 no.5
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    • pp.401-406
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    • 2007
  • The status of biodiesel (BD) production and consumption, specifications and market status in Korea are discussed in this review. The main feedstock to produce BD is soybean oil and waste cooking oil in domestic, and some companies have tried to diversify BD feedstocks. Ministry of Agriculture and Forestry (MAF) has begun a pilot project to produce BD feedstock from rapeseed for 3 years since 2007. In July 2006, Ministry of Commerce, Industry & Energy (MOCIE) and the domestic oil industry reached an agreement under which BD0.5 is supplied in market, and 158400 MT of BD would be supplied between 2007 and 2008. MOCIE reported that it will increase BD 0.5% every year to reach BD3 by 2012. It is expected that BD supply would continuously increase domestically in the future.

Electrostatic Interaction between Mercaptoundecanoic-acid Layers on Gold and ZrO2 Surfaces (금 표면 위의 메르캡토언데카노익산층 표면과 이산화지르코늄 표면 사이의 정전기적 상호작용)

  • Park, Jin-Won
    • Applied Chemistry for Engineering
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    • v.25 no.6
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    • pp.607-612
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    • 2014
  • The physical properties of mercaptoundecanoic-acid layer formed on gold surfaces, which may affect the distribution of either gold particles adsorbed to the zirconium dioxide surface or vice versa, were investigated. To conduct this investigation, the surface forces were measured between the surfaces with respect to the salt concentration and pH value using atomic force microscope (AFM). The forces were quantitatively converted by the Derjaguin-Landau-Verwey-Overbeek (DLVO) theory to the surface potential and charge density of surfaces. The converted-value dependence on the salt concentration and pH was described with the law of mass action, and the dependence was consistent with the theoretical prediction. It was found that the mercaptoundecanoic-acid layer had higher values for the surface charge densities and potentials than the $ZrO_2$ surfaces, which may be attributed to the ionized-functional-groups of the mercaptoundecanoic-acid layer.

A Study for the Screen Door System Driving Stiffness of Motor Control Method (모터 제어 방식의 스크린 도어 시스템 구동강성 검증)

  • Lee, Jung-Hyun;Lee, Seon-Bong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.4
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    • pp.2385-2390
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    • 2015
  • In the beginning run, urban railway had been required as transportation. But now days urban railway have stayed in the platform for long time, the platform is faced the problem that is improvement of environment as one of the living space. Thus, sliding automatic door on the basis of screen door have used in huge distribution market, hospital, restaurant and public office because it is comfortable that customer's convenience and entrance are controled. So screen door not only requires customer's convenience and safe, clean area and energy conservation but demands optimal design technology development of screen door system that is confirmed by element parts of design and confidence. In this paper, For secure confidence of screen door, after as modeling roller and frame's system, confirming the result for qualification of driving stiffness. And then it suggests that it is possible to increase performance and declines fraction defective of element's part.

Efficient Tag Authentication Scheme using Tag ID Identification Bits in RFID Environment (RFID 환경에서 태그 ID의 식별 비트를 이용한 효율적인 태그 인증 기법)

  • Jang, Bong-Im;Jeong, Yoon-Su;Kim, Yong-Tae;Park, Gil-Cheol
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.15 no.1
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    • pp.195-202
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    • 2011
  • RFID(Radio Frequency IDentification) is a system to identify objects and its usage is being extended to distribution, healthcare, and air&port etc. RFID is a contactless system environment, and reducing tag authentication time is important because multiple tags are identified at the same time. Studies about RFID system so far is, however, mostly to improve security vulnerability in the tag authentication process. Therefore, this paper suggests an efficient scheme to decrease the time of tag authentication which is also safe for the security of tag authentication process. The proposed scheme cuts down on the tag ID search time because it searches only the classified relevant ID in the database, which is one of many components of RFID system, by using identification bits for tag ID search. Consequently, the suggested scheme decreases process time for tag ID authentication by reducing the processing time and the load of the database. It also brings performance improvement of RFID system as it improves the energy applicability of passive tag.

Attrition Characteristics of Korean Antracite Ash in Fluidized Bed Combustors (유동층 연소로에서 국내탄 회재의 마모 특성)

  • Lee, See Hoon;Kim, Sang Done;Kim, Jae Sung;Lee, Jong Min
    • Applied Chemistry for Engineering
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    • v.17 no.5
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    • pp.547-551
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    • 2006
  • In the reactor following the American standard test method (ASTM) D5757-95 and lab-scale fluidized bed combustor, the attrition characteristics of sand and ash of Korean anthracite were investigated. The attrition characteristics, such as particle size distribution of fly ash, attrition rate, and attrition ratio etc, were studied with variation of gas velocities. The particle attrition of ash was more active than sand which was generally used as a fluidized material and also the attrition index of ash taken by ASTM D5757-95 was 5 times higher than that of sand. The formation of fine particles continuously occurred due to particle attrition with increasing gas velocities. The following equation has been suggested for attrition rate of ash. $$\frac{dW}{dt}=-3.18{\times}10^{-7}(U-U_{mf})W$$.

A Study on Mode I Interlaminar Fracture Toughness of Hybrid Composites (하이브리드 복합재료의 모드 I 층간파괴인성치에 관한 연구)

  • 김형진;곽대원;김재동;고성위
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.39 no.4
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    • pp.262-268
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    • 2003
  • This paper describes the effect of loading rate, specimen geometries and material properties for Mode I interlaminar fracture toughness of hybrid composite by using double cantilever beam (DCB) specimen. In the range of loading rate 0.2-20mm/min, there is found to be no significant effect of loading rate with the value of critical energy release rate (G_IC). The value of $G_IC$ for variation of initial crack length are nearly similar values when material properties are CF/CF and GF/GF, however, the value of $G_IC/$ are highest with the increasing initial crack length at CF/GF. The SEM photographs show good fiber distribution and interfacial bonding of hybrid composites when the moulding is the CF/GF

Preparation and Characterization of Suvarna Bhasma Parada Marit - Characterization of Suvarna Bhasma Parada Marit -

  • Thakur, Kapil;Gudi, Ramacharya;Vahalia, Mahesh;Shitut, Shekhar;Nadkarni, Shailesh
    • Journal of Pharmacopuncture
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    • v.20 no.1
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    • pp.36-44
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    • 2017
  • Objectives: The goal of this study was to characterize Suvarna Bhasma Parada Marit by using the Ayurvedic test parameters, physico-chemical tests, and various instrumentation techniques. Methods: Suvarna Bhasma, an Ayurvedic formulation manufactured as per Bharat Bhaishajya Ratnakar 5/8357 (BBR), has been studied using various instrumentation techniques: X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDAX), laser particle size distribution (PSD) analysis, fourier transform infrared spectroscopy (FT-IR), and atomic absorption spectroscopy (AAS), and physico-chemical parameters, such as the loss on drying (LOD), loss on ignition (LOI), and acid insoluble Ash (AIA) were determined. In addition, Ayurvedic tests, such as Rekhapurnatva (enterable in the furrows of the fingers), Varitaratwa (floatable over water), Nirdhoomta (smokeless), Dantagre Kach-Kach (gritty particle feeling between the teeth), were performed. Results: The XRD study showed Suvarna Bhasma to be crystalline in nature and to contain more than 98% gold. The mean size of the gold crystallites was less than 10 microns, and the morphology was globular and irregular. Suvarna Bhasma contains gold as its single and major element, with EDAX and FT-IR spectra showing that it is more than 98% pure gold. The moisture content (LOD) is less than 0.5%, the LOI is less than 2%, and the AIA is not less than 95%. The Ayurvedic tests, as specified above, helped to confirm the quality of Suvarna bhasma prepared as per the text reference (BBR). Conclusion: This chemical characterization of Suvarna Bhasma performed in this study by using modern instrumentation techniques will be helpful in understanding its pharmacological actions and will help in establishing quality protocols and specifications to substantiate the safety, efficacy & quality of Suvarna Bhasma.

Characteristics of flow field of nose-only exposure chamber for inhalation toxicity evaluation (흡입독성평가를 위한 비부노출 챔버의 유동흐름 특성)

  • Noh, Hakjae;Bong, Choonkeun;Bong, Hakyung;Kim, Yonggu;Cho, Myunghaing;Kim, Sanghwa;Kim, Daesung
    • Particle and aerosol research
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    • v.12 no.1
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    • pp.1-9
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    • 2016
  • In this work, we evaluated the characteristics of flow field and uniformity of the nose-only exposure chambers for the inhalation toxicity test. Computational fluid dynamics (CFD) modeling was carried out to demonstrate uniformity of the nose-only exposure chambers. Because it is very important in the inhalation toxicity experiments that test materials are distributed uniformly to each holder of the chamber. The test was done with these 3 types of chamber with different form to develop inhalation toxicity evaluation system, easy-to-operate system among exposure chamber used for evaluating inhalation toxicity of environmental chemical mixtures. Through CFD interpretation, nose-only exposure chamber was made with the selection of the optimal conditions. For its evaluation, one type of fragrance was selected and measured particle size distribution of each port. The gene becoming luminous to green fluorescence was combined with GPT-SPE, a type of tGFP vector, to be inhaled to the mouse. Based on this, luminous intensity was checked. As a result, total particle number concentration of each port had average value of $3.17{\times}10^6{\sharp}/cm^3$ and range of the highest and lowest concentration value was approximately ${\pm}4.8%$. Autopsy of lung tissues of mouse showed that it had clearly better delivery of gene compared to the control group.