• Journal of Korean Neurosurgical Society
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• 제44권4호
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• pp.268-272
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• 2008

Endolymphatic sac tumor is rare, locally aggressive hypervascular tumor of papillary structure, arising from the endolymphatic duct or sac in the posterior petrous bone. We present four cases with this tumor. Two patients were male and the other two were female. Age of each patient was 15, 52, 58, and 67 years. Three patients presented with progressive hearing loss and sustained vertigo for months to years and another one was referred for the tumor detected in routine medical check-up. Preoperative embolization was performed in 3 patients. Complete excision of the tumor was achieved in all patients using translabyrinthine or retrosigmoid approach. Herein, we describe the clinical and radiographic features, surgical treatment and pathologic findings with a review of the literature.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1976년도 제10차 학술대회연제 순서 및 초록
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• pp.86.1-86
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• 1976

Meniere씨 병은 1861년 Prosper Meniere에 의하여 처음으로 내이에 관한 임상증후군으로써 기술되었으며, 이후 그의 이름으로 명명되었다. 최근 저자는 2례에서 Meniere's씨 병으로 진단한 뒤 내과적 요법으로 치료하였으나 실패하여, 수술적 요법으로써 1례에서는 Cawthorne's horizontal canal labyrinthectomy를 1례에서는 endolymphatic sac decompression을 시행하여 만족할 만한 결과를 얻었기에 문헌적 고찰과 함께 보고하는 바이다.

• 대한청각학회지
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• 제24권2호
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• pp.53-60
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• 2020

Several novel animal models that represent the pathophysiological process of endolymphatic hydrops (ELH) of Meniere's disease (MD) have been developed. Animal models are important to identify and characterize the pathophysiology of ELH and to corroborate molecular and genetic findings in humans. This review of the current animal models will be useful in understanding the pathophysiology of and developing proper treatments for MD. Surgical animal models will be replaced by medication-induced animal models. Study models previously developed in guinea pigs will be developed in several smaller animals for ease of conducting molecular analysis. In this review, we provided updated resources including our previous studies regarding the current and desirable animal models for MD.

• Journal of Audiology & Otology
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• 제24권2호
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• pp.53-60
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• 2020

Several novel animal models that represent the pathophysiological process of endolymphatic hydrops (ELH) of Meniere's disease (MD) have been developed. Animal models are important to identify and characterize the pathophysiology of ELH and to corroborate molecular and genetic findings in humans. This review of the current animal models will be useful in understanding the pathophysiology of and developing proper treatments for MD. Surgical animal models will be replaced by medication-induced animal models. Study models previously developed in guinea pigs will be developed in several smaller animals for ease of conducting molecular analysis. In this review, we provided updated resources including our previous studies regarding the current and desirable animal models for MD.