• Journal of Ginseng Research
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• 제17권3호
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• pp.232-235
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• 1993

We investigated the effect of antioxidants (ascorbate, glutathione, and sodium azide), which efEectively inhibited the chlorophyll bleaching of Panax ginseng CA Meyer under the high light intensity, treated by folilar wiping on the early stage of photosynthesis and transpiration of ginseng in the 5000 $\mu$mol photon.$m^{-2}$.$s^{-1}$. Ascorbate and glutathione, endogenous antioxidant, completely recovered ginseng from the photoinhibition, but sodium azide, synthetic quencher, showed negative effect. We assumed that endogenous antioxidants could be available to the protection of the leaf-burning phenomenon of ginseng.

• 경영과학
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• 제28권3호
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• pp.31-45
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• 2011

This study aims to analyze determinants and complementarities of the technological innovation protection mechanisms of Korean manufacturing firms. The results of the inter-industry comparison show that there are differentiations of the determinants among industries. Independence between legal and strategic protection mechanisms is found in the high technology industry, whereas complementarities exist between them in the low technology industry. It implies that the firms should take into account their endogenous and exogenous factors to choose appropriate combinations of the mechanisms when they build up their innovation protection strategies. This study expects to contribute to establishing technological innovation protection strategies in manufacturing industry.

• The Plant Pathology Journal
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• 제40권5호
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• pp.486-497
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• 2024

Mosaic is the most common viral disease affecting fig plants. Although the Fig mosaic virus is the leading cause of mosaic disease, other viruses are also involved. High-throughput sequencing was used to assess viral infections in fig plants with mosaic. The genomic DNA and total RNAseq of mosaic-symptomatic fig leaves were sequenced using the Illumina platform. The analysis revealed the presence of fig badnavirus 1 (FBV-1), grapevine badnavirus 1 (GBV-1), citrus exocortis viroid (CEVd), and apple dimple fruit viroid (ADFVd). The FBV-1 and GBV-1 sequences were 7,140 bp and 7,239 bp long, respectively. The two genomes encode one open reading frame containing five major protein domains. The viroids, CEVd and ADFVd, were 397 bp and 305 bp long. Phylogenetic analyses revealed a close relationship between FBV-1 and Iranian isolates of the same species, while GBV-1 was closely related to Russian grapevine badnavirus isolates (Tem64, Blu17, KDH48, and Pal9). CEVd was closely related to other Iraqi isolates, while ADFVd was strongly related to a Spanish isolate. A registered endogenous pararetrovirus, caulimovirus-Fca1, with a size of 7,556 bp, was found in the RNA transcripts with a low expression level. This integrant was also detected in the genomes of the two lines 'Horaishi' (a female line) and 'Caprifig 6085' (a male line). Phylogenetic analyses revealed that caulimovirus-Fca1 was distinct from two other clades of different endogenous virus genera.

• 아태비즈니스연구
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• 제15권3호
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• pp.367-383
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• 2024

Purpose - This study theoretically analyzes how the level of political protection (tariff rate) is determined by political processes with conflicting interests and how it changes according to changes in global prices. Design/methodology/approach - For the purpose of the paper, against the backdrop of the apple market, which has recently become a major issue in our society due to the soaring price, we construct a mathematical model that assumes two pressure groups claiming pro-tariff and anti-tariff on the import of apples. Unlike data-based empirical studies, theoretical study has the advantage of generalization to expand related discussions and can derive policy implications from a new perspective. Findings - The analysis shows us that the equilibrium political tariff could rise or fall depending on the degree of risk aversion of the lobbyists. However, what has been clearly shown in our analysis is that domestic apple prices will fluctuate in the same direction as global prices. In other words, it is clear that even though there is a lobby for protection trade, when global prices fall, domestic prices also fall. This fact implies that apple-producing farms can decline even if tariffs on apples increase. Research implications or Originality - As long as the equilibrium political tariff rates are determined through competitive lobbying by interest groups, productive resource use is wasted from the perspective of society as a whole. Due to this waste, it can be inferred that the tariff rate determined endogenously by lobbying activities can lead to loss of welfare compared to the case of the tariff rate level, which is highly determined by the government's unilateral decision.

• 동의생리학회지
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• 제14권2호통권20호
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• pp.1-9
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• 1999

Ethanol induces compoundhemorrhagic gastric lesions and causes a dose-dependent decrease in the concentration of endogenous nonprotein sulfhydryls in rat gastric mucosa. Sulfhydryl-containing drugs protect rats from ethanol - induced gastric lesions. Based on this findings, we investigated the involvement of sulfhydryl compounds in the antioxidant effects of Puerariae radix, a traditional herbal medicine, against ethanol - induced gastric lesions in the absence and presence of iodoacetamide(IDA. sulfhydryl blocking agent) in rats. respectively. Because of the known role of sulfhydryls in gastric cytoprotection, its role in gastric antioxidation was of intrest. In vitro, Puerariae radix extract(PRE) reduced linoleic acid autooxidation and exert DPPH radical scavenging effect. In vivo. PRE increased antioxidants(SOD, catalase. GSH) and reduced lipid peroxide level in ethanol-induced gastric mucosal lesions. But treatment with PRE plus IDA significantly inhibit the antioxidant effects such as SOD and GSH but did not affect catalase levels. These results suggest that Puerariae radix may play roles in the gastric cytoprotection through antioxidant effects and increase of SOD activity and GSH level are dependent of endogenous sulfhydryls.

• Journal of Radiation Protection and Research
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• 제33권3호
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• pp.99-104
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• 2008

암 환자를 대상으로 방사선 치료빈도가 높아짐에 따라 다양한 작용 기전을 바탕으로 한 방사선 방어제 개발에 많은 노력을 경주하고 있다. 본 연구에서는 조혈, 면역세포의 증식과 다양한 싸이토카인의 분비를 증가시킴으로써 방사선 방어효능이 보고된 바 있는 인삼 다당체를 대상으로 화학적 구성성분과 각종 면역활성 지표 및 방사선 방어효능을 확인하고 가장 상관관계가 좋은 인자를 추출해내고자 하였다. 면역학적 활성으로는 임파구 증식능, 대식세포의 산화질소 분비능, AK세포 활성능을 검사하였으며 방사선 방어효과는 endogenous colony-forming unit(e-CFU)로 측정하였다. 인삼으로부터 추출된 다당체의 구성성분 중 galactose함량이 증가할수록 면역증강작용이 우수하였으며 임파구 증식능이 방사선 방어효과와 밀접한 관계가 있는 것으로 나타났다.

• Radiation Oncology Journal
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• 제33권2호
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• pp.66-74
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• 2015

Trace elements play crucial role in the maintenance of genome stability in the cells. Many endogenous defense enzymes are containing trace elements such as superoxide dismutase and metalloproteins. These enzymes are contributing in the detoxification of reactive oxidative species (ROS) induced by ionizing radiation in the cells. Zinc, copper, manganese, and selenium are main trace elements that have protective roles against radiation-induced DNA damages. Trace elements in the free salt forms have protective effect against cell toxicity induced by oxidative stress, metal-complex are more active in the attenuation of ROS particularly through superoxide dismutase mimetic activity. Manganese-complexes in protection of normal cell against radiation without any protective effect on cancer cells are more interesting compounds in this topic. The aim of this paper to review the role of trace elements in protection cells against genotoxicity and side effects induced by ionizing radiation.

• The Plant Pathology Journal
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• 제35권3호
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• pp.208-218
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• 2019

Here, we reported a novel secreted protein elicitor PeBL2 from Brevibacillus laterosporus A60, which can induce hypersensitive response in tobacco (Nicotiana benthamiana). The ion-exchange chromatography, high-performance liquid chromatography (HPLC) and mass spectrometry were performed for identification of protein elicitor. The 471 bp PeBL2 gene produces a 17.22 kDa protein with 156 amino acids containing an 84-residue signal peptide. Consistent with endogenous protein, the recombinant protein expressed in Escherichia coli induced the typical hypersensitive response (HR) and necrosis in tobacco leaves. Additionally, PeBL2 also triggered early defensive response of generation of reactive oxygen species ($H_2O_2$ and $O_2{^-}$) and systemic resistance against of B. cinerea. Our findings shed new light on a novel strategy for biocontrol using B. laterosporus A60.

• 사회복지연구
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• 제40권3호
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• pp.125-148
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• 2009

본 연구는 호스피스자원봉사자의 성격특성이 자원봉사참여와 지속의지에 미치는 영향에 대한 자원봉사동기의 매개효과에 대하여 가설적 모형을 제시 및 검증하여, 호스피스 자원봉사자 참여활성화 방안모색을 위한 이론적 근거를 제시하고자 하였다. 조사는 2007년 한국호스피스협회 추계학술대회 참석 자원봉사자 200명과 5개 호스피스 기관의 자원봉사자 132명을 대상으로 진행되었다. 연구결과를 요약하면 자원봉사 동기(보호동기, 경력동기, 관계동기, 이해동기, 가치동기를 내생변수로 친화성${\rightarrow}$자기보호동기, 친화성${\rightarrow}$경력동기, 신경증${\rightarrow}$경력동기, 친화성${\rightarrow}$관계동기, 친화성${\rightarrow}$이해동기, 친화성${\rightarrow}$가치동기, 신경증${\rightarrow}$가치동기, 외향성${\rightarrow}$가치동기의 경로가 유의하였으며, 자원봉사참여를 내생변수로 관계동기${\rightarrow}$자원봉사참여, 이해동기${\rightarrow}$자원봉사참여, 가치동기${\rightarrow}$자원봉사참여의 경로가 유의하였고, 자원봉사지속의지을 내생변수로 이해동기${\rightarrow}$자원봉사지속의지, 가치동기${\rightarrow}$자원봉사지속의지, 자봉참여${\rightarrow}$자원봉사지속의지의 경로가 유의하였다. 또한 유의한 직접효과를 중심으로 자원봉사동기의 매개효과를 검증하였으며, 이러한 결과를 바탕으로 호스피스 자원봉사자 참여활성화를 위한 제언을 제시하였다.

• The Korean Journal of Physiology and Pharmacology
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• 제2권3호
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• pp.331-343
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• 1998

Sublethal dose of bacterial lipopolysaccharide (LPS) would induce protection against cardiac ischemic/reperfusion (I/R) injury. This study examines the following areas: 1) the temporal induction of the cardio-protection produced by LPS; and 2) the relations between a degree of protection and the myocardial prostacyclin ($PGI_2$) production. Rats were administered LPS (2 mg/kg, i.v.), and hearts were removed 1, 4, 8, 14, 24, 48, 72,and 96 h later. Using Langendorff apparatus, haemodynamic differences during 25 min of global ischemia/30 min reperfusion were investigated. The concentration of $PGI_2$ in aliquots of the coronary effluent was determined by radioimmunoassay as its stable hydrolysis product $6-keto-PGF1_{\alpha}$ and lactate dehydrogenase release were measured as an indicative of cellular injury. LPS-induced cardiac protection against I/R injury appeared 4 h after LPS treatment and remained until 96 h after treatment. $PGI_2$ release increased 2-3 fold at the beginning of reperfusion compared to basal level except in hearts treated with LPS for 48 and 72 h. In hearts removed 48 and 72 h after LPS treatment, basal $PGI_2$ was increased. To determine the enzymatic step in relation to LPS-induced basal $PGI_2$ production, we examined prostaglandin H synthase (PGHS) protein expression, a rate limiting enzyme of prostaglandin production, by using Western blot analysis. LPS increased PGHS protein expression in hearts at 24, 48, 72, 96 h after LPS treatment. Induction of PGHS expression appeared in both isotypes of PGHS, a constitutive PGHS-1 and an inducible PGHS-2. To identify the correlationship between $PGI_2$ production and the cardioprotective effect against I/R injury, indomethacin was administered in vivo or in vitro. Indomethacin did not inhibit LPS-induced cardioprotection, which was not affected by the duration of LPS treatment. Taken together, our results suggest that $PGI_2$ might not be the major endogenous mediator of LPS-induced cardioprotection.