• 제목/요약/키워드: Endocrine

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식생활에서의 내분비계 장애물질에 대한 성인들의 노출 저감화 행동 분석 (Analysis of Adult Behaviors to Decrease Exposure to Endocrine Disruptors in Dietary Life)

  • 김미라;김효정
    • 동아시아식생활학회지
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    • 제21권3호
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    • pp.451-462
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    • 2011
  • The purpose of this study was to examine the level of concern and the level of knowledge of endocrine disruptors, and the level of dietary behaviors to decrease exposure to endocrine disruptors, to determine the factors affecting the level of knowledge and behaviors, and to assess the causal relationship between them. The data were collected from 579 adults in Seoul, Incheon, Daejeon, Daegu, Busan and Gwangju provinces. Frequencies, t tests, analysis of variance, Cronbach's alpha, Pearson's correlation coefficient analysis, multiple regression analyses, and path analysis were carried out by SPSS for Win V.18.0. The results of this study were as follows: The level of concern about endocrine disruptors was higher than the medium level. The respondents were most concerned about a container of cup ramen among products related to foods. The levels of both knowledge and behaviors in order to decrease exposure to endocrine disruptors in dietary life were not high. The factors affecting the level of knowledge of endocrine disruptors were educational level, attendance in education for endocrine disruptors, and concern about endocrine disruptors. On the other hand, sex, age, concern about endocrine disruptors, and the level of knowledge of endocrine disruptors affected the level of behaviors to decrease exposure toward endocrine disruptors. The results of the path analysis showed that educational level and education of endocrine disruptors had an indirect influence on the level of behaviors in order to decrease exposure to endocrine disruptors in dietary life. The concern about endocrine disruptors had both a direct and an indirect effect on the level of behaviors to decrease exposure to endocrine disruptors in dietary life. In addition, sex, age and the level of knowledge of endocrine disruptors directly affected the level of behaviors to decrease exposure to endocrine disruptors in dietary life.

REPEATED DOSE (28 DAYS) ORAL TOXICITY STUDY IN RATS, BASED ON THE PROTOCOL (OECD TEST GUIDELINE NO. 407) TO SCREEN ENDOCRINE-DISRUPTING CHEMICALS

  • Shin, Jae-Ho;Kim, Hyung-Sik;Moon, Hyun-Ju;Kim, Tae-Sung;Kang, Il-Hyun;Seok, Ji-Hyun;Ki, Ho-Yun;Shim, Eun-Yong;Jang, Hae-Jin;Jeung, Eui-Bae;Han, Soon-Young
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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    • pp.128-128
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    • 2002
  • In association with the international validation project to establish a test protocol for the "Enhanced OECD Test Guideline 407", we performed a 28-day repeated-dose toxicity study of vinclozolin (VCZ), an androgen antagonist, and ketoconazole (KCZ), a biosynthesis inhibitor of testosterone (T), and assessed the sensitivity of new parameters for detecting endocrine-related effects of endocrine-disrupting chemicals.(omitted)

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식생활 관련 내분비계 장애물질에 대한 초등학생의 인식도, 지식 및 노출저감화 행동에 관한 연구 (Recognition, Knowledge, and Behavior to Decrease Exposure toward Endocrine Disruptors in Dietary Life among Elementary School Students)

  • 김효정;김미라
    • 한국식품조리과학회지
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    • 제25권6호
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    • pp.712-724
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    • 2009
  • The purpose of this study was to examine the degree of concern about endocrine disruptors, the degree of recognition about the risk of endocrine disruptors towards humans, the degree of worry about the risk of endocrine disruptors towards ones self or family, information-obtaining behavior regarding endocrine disruptors, the degree of knowledge and the degree of behavior to decrease exposure to endocrine disruptors, and the degree of an educational need for endocrine disruptors in the dietary life of elementary school students. The data were collected from 162 students in Seoul, Incheon, Daejeon, Daegu, Busan and Gwangju. Frequencies, Cronbach's alpha, t tests, analysis of variance, Duncan's multiple range tests and chi-square tests were conducted using SPSS V.14.0 for WINDOWS. The results of this study were as follows. The degree of concern about endocrine disruptors was not high. The respondents obtained most of their information regarding endocrine disruptors from TV/radio. Respondents had difficulty in acquiring and understanding the information. Both the degree of knowledge and the degree of behavior to decrease exposure were not high. The respondents showed a high degree of educational need for endocrine disruptors, the most important was methods to prevent damage from endocrine disruptors followed by risk of endocrine disruptors.

Effects of Benomyl and Lindane during late pregnancy in the rat

  • Moon, Hyun-Ju;Shin, Jae-Ho;Lee, Su-Jung;Kang, Il-Hyun;Kim, Tae-Sung;Bae, Hoon;Ryu, Seung-Yeoul;Seok, Ji-Hyun;Ahn, Ji-Yeon;Jeung, Eui-Bae;Han, Soon-Young
    • 한국환경성돌연변이발암원학회:학술대회논문집
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    • 한국환경성돌연변이발암원학회 2002년도 Molecular and Cellular Response to Toxic Substances
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    • pp.165-165
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    • 2002
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내분비교란물질이 야생동물 및 인간의 내분비기능과 생식기능에 미치는 영향 (Effects of Endocrine Disruptors on Endocrine Function and Reproductive Function in Wildlife and Humans)

  • 류병호
    • 한국식품영양과학회지
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    • 제28권5호
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    • pp.1180-1186
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    • 1999
  • A wide ranges of chemicals released into the environment have potential to interfere with physiological and development process by disrupting endocrine pathways. Endocrine system embraces a multitude of mechanisms of action, including effect on growth, behavior, reproduction and immune function. These environmental endocrine disruptors are present in environment and pose potential health consequences to human and wildlife. The best known form in endocrine distruptors involves substances which mimic or block the action of natural hormone in the body. Endocrine disruptor have been variously defined as exogenous agents that interfere with the synthesis, secretion, transport, metabolism, binding action or elimination of the natural hormones in the body which are responsible for the maintenance of homeostasis, reproduction developmental and/or behavior. Many compounds polluted into the environment by human activity are capable of disrupting the endocrine system of animals, including fish, wildlife, and humans. Among these chemicals are pesticides, industrial chemicals, and other anthropogenic products. It has been alleged that several adverse effects on human health are linked with exposure to chemicals which are claimed to be endocrine disrupters, that is, increased incidence of testicular, prostate and female breast cancer, time dependent reductions in sperm quality and quantity, increased incidence of cryptorchidism (undescended testicles) and hypospadias(malformation of the penis), altered physical and mental de velopment in children. This observation is currently the only example of chemically mediated endocrine disruption which has resulted in a clear effect at the population level.

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