• 건축역사연구
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• 제12권3호
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• pp.7-18
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• 2003

The purpose of this study is to analyze the plan of central area in Pienza town. The nucleus of the plan was the principal square with the surrounding buildings - Cathedral, Piccolomini, Episcopal and Communal palace, focused attention on the first city plan of the Renaissance. The results of study are as follow: 1. The plan of central area in Pienza town is formed by relation with each other, in which theory including the "De re aedificatoria" of Alberti and practical plan of Pienza were united. 2. Though the plan of Pienza is not total city planning for new function and system, it has a many influence for city planning, square type and building disposition, through new project method as a result of prospective at central area in Pienza town 3. The square plan is formed of centripetal role to integrate with harmony the partial units of each other from diverse elements in scale, function, style and type of buildings, in which it can characteristics of the beginning of Renaissance. 4. Not only composition of plan, elevation and section of the Cathedral, Piccolomini and Episcopal palace, but composition of opennings are formed of proportional system of 1:1, 1:${\surd}$2, 1:2 etc.. And such proportional systems is composed of relation with each other in harmony, deciding width, length and height from among part and part, whole and part for spatial and formal composition.

• 한국대기환경학회지
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• 제24권3호
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• pp.321-328
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• 2008

The number of patient with allergic asthma and atopy have increased in the cities of Korea steadily. In order to elucidate the primary factor, we investigated whether the house dust particles collected from an apartment of the middle classes has promoting effects of allergen-related airway inflammation and airway hyperresponsiveness. Mice were treated with 0.1 mL of 1 mg/mL of house dust particles suspension by intratracheal instillation once weekly for 10 weeks combined with ovalalbumin (OVA) sensitization. Intratracheal instillation of house dust particles and OVA sensitization caused an increase in the level of serum L-lactate dehydrogenase (LDH), immunoglobulun-E (IgE) and histamine, and an elevation in respiratory resistance. It also enhanced infiltration of eosinophils in the bronchoalveolar lavage fluid (BALF) of mice, IgE and eotaxin expression in blood, and T helper type 2 cell derived cytokine levels such as of interleukin (IL)-4, IL-13 and IL-5 in the BALF. However, it did not influence T helper type 1 cytokine such as interferon-gamma in the BALF. These results indicate that house dust particles elevate allergen-related airway inflammation and airway hyperresponsiveness in mice and may play an important role in the aggravation of asthma and atopy in Korea.

• 한국정밀공학회지
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• 제30권9호
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• pp.1001-1006
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• 2013

Projection-based stereolithography is divided into constrained-surface and free-surface type according to controlling liquid layer. The constrained-surface type has a uniform layer thickness due to the use of a projection window, which covers the pattern generator such as liquid crystal display. However, the adhered resin on the projection window causes trouble and requires great separation force when the cured layer is separated from the window. To minimize the separation force, we developed a system to measure the separation force. The influence of material covering the pattern generator and the resin temperature is investigated in the system. Several structures according to the resin temperature and the velocity of z-axis elevation are compared. As a result, the fabrication condition to minimize the separation force reduces the process time.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2001년도 봄 학술발표회 논문집
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• pp.41-48
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• 2001

In this study, two factors are simultaneously considered for assessing tunnel face stability: one is the effective stress acting on the tunnel face calculated by upper bound solution; and the other is the seepage force calculated by numerical analysis under the condition of steady-state groundwater flow. The seepage forces calculated by numerical analysis are compared with the results of a model test. From the results of derivations of the upper bound solution with the consideration of seepage forces acting on the tunnel face, it could be found that the minimum support pressure for the face stability is equal to the sum of effective support pressure and seepage pressure acting on the tunnel face. Also it could be found that the average seepage pressure acting on the tunnel face is proportional to the hydrostatic pressure at the same elevation and the magnitude is about 22% of the hydrostatic pressure for the drainage type tunnel and about 28% for the water-proof type tunnel. The model tests performed with a tunnel model had a similar trend with the seepage pressure calculated by numerical analysis. From the model tests it could be also found that the collapse at the tunnel face occurs suddenly and leads to unlimited displacement.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2011년 춘계학술대회논문집
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• pp.275-277
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• 2011

KOGAS(Korea Gas Corporation) uses two-type vaporizers to send customers natural gas with imported LNG. In winter season, SMVs(SubMerged combustion Vaporizers) are mainly operated due to low seawater temperature. SMVs consume the natural gas of 1,520 $Nm^3/hr$ and emit a lot of $CO_2$ in winter time. If carbon taxes are activated on climate change, the tax burden will be severely heavy. Accordingly this work carried out numerical simulation with a commercail CFX code to investigate its possibility on the practical use of pure oxygen combustion of SMVs to reduce $CO_2$ and to improve its efficiency. First, a nozzle of a SMV's combustor is modelled. The combustion characteristics of Air/Fuel and Oxygen/Fuel are analyzed under folly insulated condition. Although we couldn't find the carbon reduction and the efficient elevation when the pure oxygen/fuel type was compared to the existing air/fuel one, we need a further study to investigate the effect of $CO_2$ recirculation.

• Biomolecules & Therapeutics
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• 제26권5호
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• pp.458-463
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• 2018

The phosphorylation of JNK is known to induce insulin resistance in insulin target tissues. The inhibition of JNK-JIP1 interaction, which interferes JNK phosphorylation, becomes a potential target for drug development of type 2 diabetes. To discover the inhibitors of JNK-JIP1 interaction, we screened out 30 candidates from 4320 compound library with In Cell Interaction Trap method. The candidates were further confirmed and narrowed down to five compounds using the FRET method in a model cell. Among those five compounds, Acebutolol showed notable inhibition of JNK phosphorylation and elevation of glucose uptake in diabetic models of adipocyte and liver cell. Structural computation showed that the binding affinity of Acebutolol on the JNK-JIP1 interaction site was comparable to the known inhibitor, BI-78D3. Our results suggest that Acebutolol, an FDA-approved beta blocker for hypertension therapy, could have a new repurposed effect on type 2 diabetes elevating glucose uptake process by inhibiting JNK-JIP1 interaction.

• 재활복지공학회논문지
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• 제8권3호
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• pp.197-203
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• 2014

본 논문은 적절한 침상머리 각도 상승을 유지하여, 인공호흡기 관련 폐렴을 예방하기 위한 의료 보조기구인 부착형 침상머리 각도 모니터링 시스템의 개발 및 성능 분석에 대한 것이다. 개발한 침상머리 각도 모니터링 시스템의 주 기능은 가시적인 침상머리 각도 디스플레이를 통하여 효과적으로 환자의 체위를 유지하도록 도움을 주며, 데이터의 수집을 통하여 환자의 증세 호전 혹은 악화와 연관된 환자의 체위에 대한 데이터베이스를 확보하는 것이다. 시스템은 손쉬운 이동을 위하여 부착형으로 구현하였으며, 데이터베이스로 활용하기 위해 휴리스틱 기법이 혼용된 FIR Filter를 사용하여 노이즈를 제거한다. 성능 분석을 위하여 광학식 엔코더와 침상머리 각도 모니터링 시스템의 측정값을 비교한다.

• 아시안잔디학회지
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• 제10권1호
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• pp.71-80
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• 1996

Fourteen dictyostelids(12 species of genus Dictyostelium. 2 species of genus Polysphonylium) oc-curred in Mt. Chiri Korea. Soils samples were collected from the nine sites. In the broadleaved-deciduous forests and conifers, common species of cellular slime molds are Dictyostelium mucoroides, and D. brefeldianum. Only two species are above 30 in importance value and above 50% in presence. Dominant species in the broadleaved-deciduous forests is D. mecoroides wheras in the conifer forests is D. brefeldianum which was not common until now in Korea, found in the low elevation either. In addition, Five cellular slime molds occured in the Miscanthus sinensis community: 4 species of genus Dictyostelium and 1 species of genus Polysphonylium. Dominant species is D. purpureum. Importance value is very high, 85. This Result is exceptively unusual. It dind't occur in the other sites. Correlation between the altitudes and the occurrence and distribution of dictyostelids was not accurate. Merely dominant species were different according to forest types and organic matter contents in soil. Cellular slime molds have different favorite forest types. And the growth and germination are dependent on the soil enviroryrnental conditions and soil quility. Key words:Dictyostelids, Mt. Chiri D. mecoroides, D. brefeldianum. D. purpureum. Soil quility, Favorite forest type, Soil environmental condition.

• Journal of Positioning, Navigation, and Timing
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• 제11권4호
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• pp.297-304
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• 2022

The models used for ionosphere error correction in positioning using Global Navigation Satellite System (GNSS) are representatively Klobuchar model and NeQuick model. Although these models can correct the ionosphere error in real time, the disadvantage is that the accuracy is only 50-60%. In this study, a method for polynomial modeling of Global Ionosphere Map (GIM) which provides Vertical Total Electron Content (VTEC) in grid type was studied. In consideration of Ionosphere Pierce Points (IPP) of satellites with a receivable elevation angle of 15 degrees or higher on the Korean Peninsula, the target area for model generation and provision was selected, and the VTEC at 88 GIM grid points was modeled as a polynomial. The developed VTEC polynomial model shows a data reduction rate of 72.7% compared to GIM regardless of the number of visible satellites, and a data reduction rate of more than 90% compared to the Slant Total Electron Content (STEC) polynomial model when there are more than 10 visible satellites. This VTEC polynomial model has a maximum absolute error of 2.4 Total Electron Content Unit (TECU) and a maximum relative error of 9.9% with the actual GIM. Therefore, it is expected that the amount of data can be drastically reduced by providing the predicted GIM or real-time grid type VTEC model as the parameters of the polynomial model.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2022년도 학술발표회
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• pp.155-155
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• 2022

Low head, ogee spillways is popularly used to defense against floods as well as to provide water for irrigation. Spillway is also used to assess compliance with water quality regulations by controlling amount of discharge to the downstream of a channel. For the purpose of water resource management and/or environmental aspects as explained above, the flow discharge through spillways need to be correctly rated as a function of geometry and hydraulic variables. Typically, four flow conditions are encountered during the operation of spillway: (a) uncontrolled free flow (UF); (b) uncontrolled submerged flow (US); controlled free flow (CF); and controlled submerged flow (CS), and each condition has a unique rating equation. However, one of the tricky part of the spillway operation is finding correct flow type over the spillway because structures can operate under both submerged and free flow conditions, and the types are continuously changing over time depending on the amount of discharge, head water and tail water elevation. Quite obviously, if the wrong rating curve relationship is applied because of misjudgment of the flow type due to a transition, a serious error can occur. Thus, an hydraulic model study of one of spillway structure located in South Florida was conducted for the purpose of developing transition relationships. In this presentation, US to UF transition is highlighted.