• Korean Journal of Acupuncture
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• 제36권3호
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• pp.162-170
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• 2019

Objectives : Increasing evidence suggests that parasympathetic vagus nerve activity plays a role in modulating acupuncture-induced anti-inflammatory reaction, but the function of sympathetic nerve is not known. Here, we investigated whether splanchnic sympathetic nerve activity was involved in the regulation of splenic expression of $TNF-{\alpha}$ mRNA by electroacupuncture (EA) in LPS-injected animals. Methods : DiI was injected into the stomach or celiac ganglion (CG) for retrograde labeling of the target tissues. EA was given at ST36 and the electrical stimulation on the sciatic nerve in LPS-injected mice. c-Fos signals in the tissues were analyzed by immunofluorescence staining, and $TNF-{\alpha}$ mRNA was analyzed by real-time PCR. Results : Application of EA at ST36 or electrical stimulation on the sciatic nerve induced c-Fos expression in neurons of the spinal cord and celiac ganglion (CG). Then, the vagotomy reduced c-Fos levels in CG neurons but not in the spinal cord in animals given EA. Expression of $TNF-{\alpha}$ mRNA which was induced in the spleen after LPS was significantly inhibited by EA, then the vagotomy elevated $TNF-{\alpha}$ mRNA level similar to that in LPS-injected animals. Splanchnectomy in animals given LPS and EA also increased $TNF-{\alpha}$ mRNA though it was less effective than vagotomy. Conclusions : Our data suggest that EA delivered to the spleen via the splanchnic sympathetic nerve may be involved in attenuating splenic inflammatory responses in LPS-injected animals.

• 한방재활의학과학회지
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• 제25권3호
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• pp.91-102
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• 2015

Two patients, diagnosed as cervical spinal cord injury, were hospitalized and treated by Korean medical interventions with Functional Electrical Stimulation (FES). The range of motion of the shoulder joint, manual muscle test were adopted to measure the resulting motor recovery after treatment. And the Korean version of Barthel index (K-MBI) was adopted as a method of measuring the improvement of quality of life after treatment. The range of motions and muscle strengths of the shoulder joints were improved. The activities of daily living were slightly improved in case 2, but showed no improvement in case 1. FES was effective for upper extremities rehabilitation of spinal cord injured patients. Further studies are needed to set up an Korean medical protocol for spinal cord injury rehabilitation.

• 한국전문물리치료학회지
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• 제4권1호
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• pp.87-94
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• 1997

The purposes of this study were 1) to determine the changes between pre-treatment and post-treatment of four groups of 15 persons each and 2) to compare the effect of conventional transcutaneous electrical nerve stimulation(TENS) and laser at auricular acupuncture points on experimental pain threshold measured at the wrist. Sixty healthy adult men and women(M:32, F:28), aged 20 to 28 years, were assigned randomly to one of four groups. Group 1 received TENS to the appropriate auricular point for wrist pain, Group 2 received laser to the appropriate auricular point for wrist pain, Group 3 received placebo TENS to the appropriate auricular point for wrist pain, Group 4 received no treatment and served as controls. Experimental pain threshold at the wrist was determined with a painful electrical stimulus before and 20 minutes after ear stimulation. Group 1 was the only group that showed a stastically significant increase (p<0.05) in pain threshold after treatment whereas the Group 2,3 and 4 did not. These results suggest that TENS has the capability to higher pain threshold but laser does not.

• 대한물리치료과학회지
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• 제9권4호
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• pp.53-61
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• 2002

This study was carried out to investigate the effects of electrical stimulation on the change oxytocin(OT) immunoreactive cells in the hypothalamus of the male SD rats. Fifteen healthy and normal male rats were divided into three groups, 5 SD rat in each group. The one group has been stimulated by electro-acupuncture(EA, 2Hz) for 30 min and the other group by EA for 1hr 30 min and control group has not been stimulated. The results were summarized as follows. OT immunoreactive cells were found in the Paraventricular nucleus (PVN), Supraoptic nucleus(SON) and Lateral Magnocellular Area(LMA). The number of OT immunoreactive cells of PVN were significantly increased after 30 min as compared with control group (p<0.05) and were also significantly increased after 1hr 30min than 30 min(p<0.05). The number of OT immunoreactive cells of SON were significantly increased after 30 min and 1hr 30 min(p<0.05) as compared with control group, but decreased after 1hr 30 min than 30 min. The number of immunoreactive hells of LMA significantly increased after 30 min(p<0.05) as compared with control group, but significantly decreased after 1hr 30 min than 30 min(p<0.05). These results show that OT is released into the hypothalamus in response to electrical stimulation.

• 동력기계공학회지
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• 제10권1호
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• pp.83-89
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• 2006

Recently, the seriousness of high blood pressure was appeared as the most frequent disease of a the whole sickness in the world. However, the treatment of this disease is uncertain and produces an adverse reaction of a medicine therapy. Also, the patients are burdened with a fee for medical treatment. Therefore, in this paper, we studied effectively and financially to execute the treatment of high blood pressure using the Chinese medicine theorem that is recently arousing the great interest of the people. The main theories in this paper are blood vessel theory and acupuncture, respectively. Especially, the composed circuit systems are classified the blood pressure depressor part and the meridian points discrimination part, respectively. The blood pressure depressor part is composed generally of low-frequency generation circuit, charging-discharging circuit, and micro-computer circuit. Finally, this research have the advantage of discrimination parts such as regular voltage generating circuit, stimulus circuit, amplifying circuit, and alarm circuit.

• 대한소아치과학회지
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• 제25권4호
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• pp.788-796
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• 1998

The purpose of this study was to investigate the effect of various electroacupuncture duration induced by acupuncture point-Zusanli ($S_{36}$) electrical stimulation on inhibition of amplitude of digastric electromyogram (dEMG) evoked by noxious electrical stimuli around the mental foramen. intraperitoneal sodium pentobarbital in an initial dose of 50mg/kg and maintenance doses of 4.5mg/kg/h were given through a cannula in the femoral vein using a constant infusion pump. A pair of stimulating electrodes were inserted for noxious stimuli around the mental foramen. An irritant electronic stimuli pulse (0.2 Hz, 0.1 ms duration) was produced with an intensity of about $1.5{\times}2$ times threshold for evoking the dEMG. The anterior belly of the digastric muscle was exposed and a pair of 0.1mm wire electrodes were inserted for dEMG recording. Acupuncture point stimulation on Zusanli (2 Hz, 250 ${\mu}s$, biphasic pulse, 2 V) was delivered by Dental Electronic Anesthesia (3M, U.S.A). For periods of electronic stimulation of 10, 20, and 30min, the amplitudes of dEMG were measured on the oscilloscope and on the monitor connected to the amplifier. The following results were obtained: The dEMG was decreased to 73.4% of that in the control set after 10 min electroacupunture stimulation (Group I); The dEMG was decreased to 77.1% (10min), 54.0.% (20min) of that in the control set after 20minutes of electroacupunture stimulation (Group II). The dEMG was decreased to 73.3% (10min), 61.9% (20min), 76.2% (30min) of that in the control set after 30 min of electroacupunture stimulation (Group III). From these results, it may be that in the electroacupuncture stimulation on the Zusnali resulted in a reduction of amplitude of dEMG and that the most effective electroacupuncture stimulation period was 20min.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2007년도 추계종합학술대회
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• pp.170-174
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• 2007

뇌파에 관한 연구는 의학 및 공학 분야에서 많이 활성화 되어 있지만, 침구학에서의 뇌파분석에 과한 연구는 아직 많이 이루어져야 할 부분 중 하나이다. 그러므로 본 연구는 침구요법 중 간접 뜸 자극에 의한 뇌파를 분석하고 자율신경계와의 상관관계를 분석을 하고자 한다. 본 연구의 실험은 간접 쑥 뜸을 인체의 중완, 신궐, 관원의 경혈 점에 자극하고, 자극 전, 자극 중, 자극 후 1시간, 그리고 자극 후 2시간 일 때의 뇌파를 측정한다. 그리고 측정된 데이타는 Matlab 7.0을 이용하여 FFT 및 주파수 파워 스펙트럼을 적용하여 ${\alpha}$, ${\beta}$, ${\delta}$, ${\theta}$파 성분을 자극 단계별로 나누어 주파수 각 성분 비율의 변화, 그리고 진폭의 크기변화량에 대하여 분석 고찰하였다. 본 연구의 결과, EEG 데이터를 FFT를 적용하여 ${\alpha}$, ${\beta}$, ${\delta}$, ${\theta}$파의 비율을 분석한 결과 ${\alpha}$파가 자극 전보다 자극 후 약 2배 정도 증가하는 것을 알 수 있었다. 그리고 전체의 파워스펙트럼 분석에서 ${\alpha}$파, ${\beta}$파의 에너지가 전체적으로 감소하므로 부교감신경이 활성화됨을 알 수 있었다. 본 연구와 기존 연구의 결과를 비교해 보면, 간접 뜸 자극은 자율신경계의 변화에 영향을 줄 수 있으며 ${\alpha}$파의 비율적 증가로 긴장 상태나 스트레스 상태의 사람에게 안정을 가져다 줄 수 있음을 확인 할 수 있었다.

• The Korean Journal of Pain
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• 제6권2호
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• pp.208-212
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• 1993

1990년 5월부터 1993년 4월까지 알레르기성 비염으로 대구가톨릭대학 병원 통증치료실을 방문한 환자를 대상으로 하여 SGB와 E-AP로 병용 치료 하였는바 2회 이상 시행한 49명을 본 대상으로 하여 회고적으로 관찰하였다. 나이는 7세에서부터 70세까지로 평균 34.1세 였으며, 연령별로는 41~50세 사이가 많았으며, 내원 계절별로는 가을과 여름 순으로 많았다. SGB의 평균 시행 횟수는 $6.02{\pm}4.29$회였고, E-AP의 평균 시행 횟수는 $7.15{\pm}5.57$회였다. 환자의 병력은 평균 $5.53{\pm}7.10$년 이었으며, 1주일에서 30년까지 다양하였다. 6개월 이하의 병력시 SGB의 평균 시행 횟수가 $3.13{\pm}1.81$회로 6개월 이상 병력시의 평균 시행 횟수 $6.51{\pm}4.40$회 보다 통계적으로 의의있게 적었으며, 또한 치료기간도 6개월 이상 병력시의 $49.67{\pm}37.30$일 보다 6개월 이하 병력시의 $18.00{\pm}14.88$ 일이 통계적으로 의의있게 짧았다. 24명의 남자중 1명이, 25 명의 여자중 1명이 재발 내원하여 재 치료하였다. 치료 도중에 1명의 남자와 1명의 여자에게서 연하곤란증이 있었고, 1명의 여자에게서 4~5시간의 애성이 있었으나 그 후 정상으로 회복되었다. 본 질환은 일단 발병 하게되면 그 원인 규명도 어려울 뿐만 아니라 치료 역시 재발 악화 등 개운치 않은 질환인데도 전기침자극과 국소마취제에 의한 성상신경절 차단등 비교적 간단한 방법으로 매우 효과적인 반응을 얻게 되어 향후 널리 보급될 것으로 사료된다.

• 대한한방내과학회지
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• 제39권2호
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• pp.247-252
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• 2018

A 58-year-old woman came into our clinic with headache, dizziness, and malaise after an electrical injury. Even though she received conventional treatment about five weeks after the injury, the symptoms did not improve, and she decided to undergo traditional Korean medicine treatment. During a 20-day hospital stay with acupuncture and herbal medicine, the symptoms were reduced to about half, and after six months of further treatment in the outpatient clinic, there was no pain during the day and only moderate headaches occurred intermittently after intense physical activity. As far as we know, this is the first report to treat the aftereffects of electrical injury with traditional Korean medicine treatment. Hence, here we tried to fully describe and announce the detailed progress of the patient through this report.

• 한국융합학회논문지
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• 제10권6호
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• pp.79-87
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• 2019

본 연구는 건강한 성인남녀를 대상으로 경혈지점에 은침전기자극과 침형 경피신경전기자극을 적용하여 혈류량과 통증 역치에 미치는 효과를 알아보고자 하였다. 성인남녀 32명을 대상으로 SSP group (n=18), A-TENS group (n=14)으로 무작위 배정하여 적용하였다. 혈류량을 측정하기 위해 레이저 도플러 영상을 사용하였고, 통증 역치를 측정하기 위해 압통측정기를 사용하였다. 집단 내 혈류량의 변화는 두 그룹 사이에서 유의한 차이가 있었고(p<0.05), 압통 역치의 변화는 SSP group에서만 유의한 차이가 있었다(p<0.05). 중재 후 집단 간 혈류량과 압통 역치의 변화에서는 SSP group과 TENS group 사이에서 유의한 차이가 있었다(p<0.05). 결과적으로 경혈지점에 SSP와 A-TENS을 적용한 결과 혈류량과 압통 역치의 변화가 있었으며, 특히 SSP을 경혈지점에 적용할 때 더욱 큰 변화를 볼 수 있었다. 이러한 결과를 바탕으로 경혈과 전기자극치료의 융합이 다양한 환자를 위한 방법의 하나로 유용하게 적용할 수 있으며, 지속적인 융합중재개발이 필요하다.