• The Journal of Korean Physical Therapy
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• v.12 no.1
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• pp.49-56
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• 2000

The purpose of this study was to investigate the influnce of afferent stimuli, transcutaneous electrical nerve stimulation and ultra sound, on the electrdiagnostic study of normal subjects. Electrodiagnostic study was performed before and after the application of afferent stimulation of the right popliteal fossa on 18 healthy female volunteers. After the transcutaneous electrical nerve stimulation, there is no significantly change of latencies and amplitudes of SEP, H-reflex, peroneal nerve F-wave, and sensory nerve conduction. After the ultra sound, there is no significantly change of latencies and amplitudes of SEP, H-reflex, peroneal nerve F-wave, and sensory nerve conduction. Tibial nope F-wave and motor nerve shows prolonged latency after TENS and US (p<0.01). Ultrasound may have a similar mechanism of action compared to transcutaneous electrical nerve stimulation by having localized inhibitory effects of the peripheral nerve. However, further investigation is needed to assess their mechanism of action and the precise relevance of stimulation modality.

• Journal of the Korean Institute of Intelligent Systems
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• v.23 no.2
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• pp.178-183
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• 2013

In this study, we proposed a method for electroencephalogram (EEG) classification using invariant CSP at special channels for improving the accuracy of classification. Based on the naive EEG signals from left and right hand movement experiment, the noises of contaminated data set should be eliminate and the proposed method can deal with the de-noising of data set. The considering data set are collected from the special channels for right and left hand movements around the motor cortex area. The proposed method is based on the fit of the adjusted parameter to decline the affect of invariant parts in raw signals and can increase the classification accuracy. We have run the simulation for hundreds time for each parameter and get averaged value to get the last result for comparison. The experimental results show the accuracy is improved more than the original method, the highest result reach to 89.74%.

• Journal of Yeungnam Medical Science
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• v.7 no.1
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• pp.19-27
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• 1990

This investigation was undertaken to clarify the in vitro effect of the various stimulations, such as exercise(E), insulin(I), direct electrical stimulation(EST) and the combinations of the above, on the glucose incorporation into glycogen molecules (glycogen synthesis) of the normal slow(soleus) and fast twitch(plantaris) muscles, and the different responses of slow and fast twitch muscles to persistent overloads causing compensatory muscle hypertrophy. In resting state, slow twitch muscle has greater capacity for glycogen synthesis than fast twitch muscle, and responses of different muscle to various stimuli were differ as follows : In slow twitch muscle, the glycogen synthesis was increased by insulin, and electrical stimulation but not increased by exercise ; exercise increased insulin sensitivity and the effect of electrical stimulation. Whereas the glycogen synthesis in fast twitch muscle was increased only by the stimuli combined with E and EST, and E, I, and EST. As the result of removal of synergistic muscle, both muscles were hypertropied, and the degree of hypertrophy in response to persistent overload was higher in fast twitch muscle(182%) than slow twitch muscle(151%). In hypertrophied muscles, glycogen synthesis of soleus in any groups was lower than that of the control, but similar in plantaris. In conclusions, there were marked heterogeneity in defferent muscle fiber in the effects of exercise and insulin addition and electrical stimulation on muscle glycogen synthesis, and fast twitch muscle may be adapted more easily to that kind of persistent overload than slow twitch muscle.

• Journal of Sensor Science and Technology
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• v.17 no.1
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• pp.1-8
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• 2008

Recently, capsule endoscope was developed to observe small intestine in human body. However, the capsule does not have any locomotive ability, which reduces the benefit of the capsule endoscope. Many researches have done to give locomotion to the capsule, still it consumes too much power to generate the motion by small battery. One of the moving method is electrical stimulus that consumes less power than many methods. The electrical stimulus method causes contraction in the small intestine, and it moves the capsule. Some of papers showed it is possible to guide the capsule by electrical stimulus, however the relationship between electrical stimulus at the mucous and contraction force in the small intestine is not reported, yet. In this paper, the mucous in the small intestine was stimulated, and measured the contraction force in the small intestine is shown. The result shows, the relationship between electrical stimulus parameters (voltage, duration) and contraction force. Also, equation between electrical stimulus parameters and contraction force is roughly induced.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.86-89
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• 1995

A clinically oriented 32 channel Electroencephalogram (EEG) and evoked potential (EP) mapping system has been developed. The EEG and EP signals acquired from 32-channel electrodes are amplified by the pre-amplifier located near patient and are then tither amplified by main amplifier. An automatic artifact rejection scheme is employed using a neural network by which examination time is reduced substantially. Auditary and visual stimuli are used for the evoked potential mapping. A user-friendly graphical interface based on the Microsoft Window 3.1 is developed for the operation of the system. Statistical databases for the poop and individual comparisons are also included to support statistically based diagnosis.

• Journal of Biomedical Engineering Research
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• v.27 no.6
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• pp.384-391
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• 2006

Variation of brain dynamics under Zen meditation has been one of our major research interests for years. One issue encountered is the inaccessibility to the actual meditation level or stage as a reference. In this paper, we propose an alternative strategy for investigating the human brain in response to external flash stimuli during Zen meditation course. To secure a consistent condition of the brain dynamics when applying stimulation, we designed a recording of flash visual evoked potentials (F-VEPs) based on a constant background EEG (electroencephalograph) frontal $\alpha-rhythm$ dominating activities that increase significantly during Zen meditation. Thus the flash-light stimulus was to be applied upon emergence of the frontal $\alpha-rhythm$. The alpha-dependent F-VEPs were then employed to inspect the effect of Zen meditation on brain dynamics. Based on the experimental protocol proposed, considerable differences between experimental and control groups were obtained. Our results showed that amplitudes of P1-N2 and N2-P2 on Cz and Fz increased significantly during meditation, contrary to the F-VEPs of control group at rest. We thus suggest that Zen meditation results in acute response on primary visual cortex and the associated parts.

• Journal of Acupuncture Research
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• v.38 no.4
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• pp.300-311
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• 2021

Background: So far there is no confidence in the basics of acupoint/meridian phenomena, specifically in spatial and temporal electrical manifestations in the skin. Methods: Using the skin electrodynamic introscopy, the skin areas of 32 × 64 mm² were monitored for spectral electrical impedance landscape with spatial resolution of 1 mm, at 2 kHz and 1 MHz frequencies. The detailed baseline and 2D test-induced 2 kHz-impedance phase dynamics and the 4-parameter time plots of dozens of individual points in the St32-34 regions were examined in a healthy participant and a patient with mild gastritis. Non-thermal stimuli were used: (1) (for the sick subject), microwaves and ultraviolet radiation applied alternately from opposite directions of the meridian; and (2) (for the healthy one) microwaves to St17, and cathodic/anodic stimulation of the outermost St45, alternately. Results: In both cases, the following phenomena have been observed: emergence of in-phase and/or antiphase coherent structures, exceeding the acupoint conditional size of 1 cm; collective movement along the meridian; reversible with a reversed stimulus; counter-directional dynamics of both whole structures and adjacent points; local abnormalities in sensitivity and dynamics of the 1 MHz and 2 kHz parameters indicating existence of different waveguide paths. Conclusion: It is assumed that these findings necessitate reconsideration of some basic methodological issues regarding neurogenic/acupuncture points as spatial and temporal phenomena; this requires development of an appropriate approach for identifying the acuzones patterns. These findings may be used for developing new approaches to personalized/controlled therapy/treatment.

• The Korean Journal of Pain
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• v.12 no.1
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• pp.64-69
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• 1999

Background: The new drug HP228 is a cytokine restraining agent with a broad spectrum of anti-inflammatory, analgesic, and antipyretic activity. Six healthy, adult, male volunteers were studied to determine the independent and interactive effects of HP228 and morphine on pain perception. Methods: Two groups of stimuli were applied to each volunteers before drug administration as control, 20 min after morphine and HP228 administration, and 20 min after combined administration of these two drugs. Two adhesive electrically-conducting pads were applied on opposite sides of the arm approximately 8 cm apart. The electrode were connected to an electrical impulse generator and 50 Hz 1 msec pulses of incrementally increasing intensity were delivered at 1 sec intervals. The analgesic endpoints were the current intensity (mA) at which the subject first detected the stimulus (THRESH), the intensity at which the stimulus was first idenfied as being painful (PAIN), and the intensity at which the subject requested that the stimulus be terminated due to discomfort (LIMIT). A second series of stimuli were applied immediately thereafter using 1-sec duration 50 Hz tetanus pulses with increasing intensities at 2~5 sec intervals. Results: There were significant differences between drug treatments (Morphine, HP228, HP228/Morphine) and control (No drugs) in any of the measurements (PAIN, LIMIT) except THRESH with the twitch and tetanus test. Conclusions: The data suggests that HP228 is an analgesic, but it does not appear to interact with morphine in an additive manner.

• Progress in Medical Physics
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• v.9 no.2
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• pp.95-104
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• 1998

The dynamic properties of the 3rd-order neuron of the retina was investigated by using conventional intracellular recording techniques. Experiments were performed in the superfused retina-eyecup preparation of the channel catfish, Ictalurus punctatus. The cornea, iris, lens, and vitreous were removed by absorption with Kimwipe tissue under the dissection microscope thereby exposing the retina in a hemi -eyecup. The electrical signal was amplified by electrometer, viewed on oscilloscope. Regular signals from the cells were recorded on a penwriter and stored by data recorder and computer. Full-field, spot or annular light stimuli were generated on a computer monitor and focused onto the retina. Baclofen hyperpolarized the dark membrane potential, suppressed sustained component and enhanced transient component of the ON-sustained cell with a large transient component, but did not affect the surround antagonism of the cell. Baclofen selectively suppressed responses evoked by moving bar light stimuli on the ON-OFF transient cell. The results suggest that transient cells have directional selectivity in the inner retina. These dynamic properties of amacrine and ganglion cells were modulated by baclofen. Therefore, it is presumed that there is baclofen-induced directional selectivity in ON-OFF transient cells in the catfish retina.

• Journal of Korea Multimedia Society
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• v.9 no.3
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• pp.360-368
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• 2006

Recently, performance of the mobile phone has increased dramatically. Due to this, it is possible to integrate various biotechnology. There are many ventures to integrate biotechnology with mobile phone, because of increasement interest of peoples well-being. The transcutaneous electrical nerve stimulation can Improve the circulation of blood and suppress a pain. To integrate the transcutaneous electrical nerve stimulation with mobile phone, it is necessity to make small, low power, and safe module. In this paper, the transcutaneous electrical nerve stimulation module is designed and implemented by small boost convertor. The value of tank capacitor, which is the total stimulus energy to human, can be chosen to insure safe condition. The confirm the of operation of designed module, a small micro-controller is used to make system and test the module. The implemented system is small and consumes a low enough power to be integrated with mobile phone.