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Spatial and Temporal Electrodynamics in Acuzones: Test-Induced Kinematics and Synchronous Structuring. Phenomenological Study

  • Babich, Yuri F. (Center of the Skin Electrodynamic Introscopy) ;
  • Babich, Andrey Y. (Center of the Skin Electrodynamic Introscopy)
  • Received : 2021.07.16
  • Accepted : 2021.09.07
  • Published : 2021.11.30

Abstract

Background: So far there is no confidence in the basics of acupoint/meridian phenomena, specifically in spatial and temporal electrical manifestations in the skin. Methods: Using the skin electrodynamic introscopy, the skin areas of 32 × 64 mm2 were monitored for spectral electrical impedance landscape with spatial resolution of 1 mm, at 2 kHz and 1 MHz frequencies. The detailed baseline and 2D test-induced 2 kHz-impedance phase dynamics and the 4-parameter time plots of dozens of individual points in the St32-34 regions were examined in a healthy participant and a patient with mild gastritis. Non-thermal stimuli were used: (1) (for the sick subject), microwaves and ultraviolet radiation applied alternately from opposite directions of the meridian; and (2) (for the healthy one) microwaves to St17, and cathodic/anodic stimulation of the outermost St45, alternately. Results: In both cases, the following phenomena have been observed: emergence of in-phase and/or antiphase coherent structures, exceeding the acupoint conditional size of 1 cm; collective movement along the meridian; reversible with a reversed stimulus; counter-directional dynamics of both whole structures and adjacent points; local abnormalities in sensitivity and dynamics of the 1 MHz and 2 kHz parameters indicating existence of different waveguide paths. Conclusion: It is assumed that these findings necessitate reconsideration of some basic methodological issues regarding neurogenic/acupuncture points as spatial and temporal phenomena; this requires development of an appropriate approach for identifying the acuzones patterns. These findings may be used for developing new approaches to personalized/controlled therapy/treatment.

Keywords

Acknowledgement

This work did not receive any funding. We are grateful for all possible help and good advice gained in the past from: Prof. J. Jossinet (France), Mrs. S. M. Weinstein (USA), Prof. M. Y. Antomonov, Prof. V.B. Maksymenko and Prof. O.E. Kovalenko (all from Ukraine) And of course, under our circumstances, development of this initiative project would hardly have been possible without the USA & Canada grant STCU#1822, 2001-2004, http://www.stcu.int.

References

  1. Stux G, Berman B, Pomeranz B. Basics of acupuncture. Berlin (Germany): Springer; 2003
  2. Geng L, Jie-Ming L, Pei-Wen L, Xiaoqiang Y, Peter ZP, Wei L et al. Physiology and cell biology of acupuncture observed in calcium signaling activated by acoustic shear wave. Pflugers Arch 2011;462:587-597. https://doi.org/10.1007/s00424-011-0993-7
  3. Chen S, Miao Y, Nan Y, Wang Y, Zhao Q, He E et al. The Study of Dynamic Characteristic of Acupoints Based on the Primary Dysmenorrhea Patients with the Tenderness Reflection on Diji (SP 8). Evid Based Complement Alternat Med 2015;2015:158012.
  4. Choi EM, Jiang F, Longhurst JC. Point specificity in acupuncture. Chin Med 2012;7:4. https://doi.org/10.1186/1749-8546-7-4
  5. Nierhaus T, Pach D, Huang W, Long X, Napadow V, Roll S et al. Difficulties Choosing Control Points in Acupuncture Research. Front Hum Neurosci 2016;10;404.
  6. Baumler PI, Simang M, Kramer S, Irnich D. Acupuncture point localization varies among acupuncturists. Forsch Komplementmed 2012;19:31-37. https://doi.org/10.1159/000335825
  7. Colbert AJ. The ongoing debate: Do acupuncture points have lower skin resistance than nonacupuncture sites? J Altern Complement Med 2009;15:1059. https://doi.org/10.1089/acm.2009.0308
  8. Li F, He T, Xu Q, Lin LT, Hui Li, Liu Y et al. What is the Acupoint? A preliminary review of Acupoints. Pain Medicine 2015;16:1905-1915. https://doi.org/10.1111/pme.12761
  9. Tn H, Tumilty S, Chapple C, Liu L, McDonough S, Yin H et al. Understanding Acupoint Sensitization: A Narrative Review on Phenomena, Potential Mechanism, and Clinical Application. Evid Based Complement Alternat Med 2019;2019:6064358.
  10. Li J, Wang Q., Liang H, Dong H, Li Y, Ng EH et al. Biophysical characteristics of meridians and acupoints: A systematic review. Evid Based Complement Alternat Med 2012;2012;793841.
  11. Litscher G. No, there is no conclusive scientific evidence for visualization of meridians at the moment. J Altern Complement Med 2014;20:215-216. https://doi.org/10.1089/acm.2013.0150
  12. Kramer S, Winterhalter K, Schober G, Becker U, Wiegele B, Kutz DF et al. Characteristics of electrical skin resistance at acupuncture points in healthy humans. J Altern Compl Med 2009;15:495-500. https://doi.org/10.1089/acm.2008.0331
  13. Ahn AC, Martinsen OG. Electrical characterization of acupuncture points: technical issues and challenges. J Altern Complement Med 2007;13:817-824. https://doi.org/10.1089/acm.2007.7193
  14. Martinsen OG, Grimnes S, Morkrid L, Hareide M. Line patterns in the mosaic electrical properties of human skin-a cross-correlation study. IEEE Trans Biomed Eng 2001;48:731-734. https://doi.org/10.1109/10.923791
  15. Ahn AC, Colbert AP, Anderson BJ, Martinsen OG, Hammerschlag R, Cina S et al. Electrical properties of acupuncture points and meridians: A systematic review. Bioelectromagnetics 2008;29:245-256. https://doi.org/10.1002/bem.20403
  16. Reichmanis M, Marino AA, Becker RO. Electrical correlates of acupuncture points. IEEE Trans Biomed Eng 1975;22:533-535. https://doi.org/10.1109/TBME.1975.324477
  17. Teplan M, Kukucka M, Ondrejkovicova A [Internet]. Bioelectrical properties of human body Impedance analysis of acupuncture points. Available from: https://explore.scimednet.org/wp-content/uploads/2017/07/Teplanbioelectric.pdf.
  18. Colbert AP, Larsen A, Chamberlin S, Decker C, Schiffke HC, Gregory WL et al. A multichannel system for continuous measurements of skin resistance and capacitance at acupuncture points. J Acup Meridian Stud 2009;2:259-268. https://doi.org/10.1016/S2005-2901(09)60066-2
  19. Gow BJ, Cheng JL, Baikie IG, Martinsen OG, Zhao M, Smith S et al. Electrical Potential of Acupuncture Points: Use of a Noncontact Scanning Kelvin Probe. Evid Based Complement Alternat Med 2012;2012:632838.
  20. Chen RX, Kang MF, Chen MR. Return of Qibo: On hypothesis of sensitization state of acupoints. Zhongguo Zhen Jiu 2011;31:2134-2138.
  21. Tan H, Tumilty S, Chapple C, Liu L, McDonough S, Yin H et al. Understanding Acupoint Sensitization: A Narrative Review on Phenomena, Potential Mechanism, and Clinical Application. Evid Based Complement Alternat Med 2019;2019:6064358.
  22. Babich JF. Impedanz-Bild (Introscopie) von biologischen Gewebe Verfahren. Deutsche Zeitschrift fur Akupunktur 1992;35:93-97,103-109.
  23. Babich YF. The skin 2D electrobioimpedance response to a remote non-thermal mm-EMF exposure. 2d Int Conf on Bioelectromagnetism Melbourne(Australia);1998.
  24. Babich YF. Quasistationary and autowave structures of the skin electrobioimpedance relief. Reports of the Ukranian NAS; 2000. Report No.4. 4 p.
  25. Wang GJ, Ayati MH, Zhang WB. Meridian studies in China: A systematic review. J Acupunct Meridian Stud 2010;3:1-9. https://doi.org/10.1016/S2005-2901(10)60001-5
  26. Xu J, Yang F,Han D,Wang Z, HongY,Han H, Xu S. Low impedance nature of 12 acupoints on the limbs, and the unexpected dependence on limb angle. J Tradit Chin Med 2018;38:287-298. https://doi.org/10.1016/j.jtcm.2018.03.005
  27. Babich Y, Nuzhdina M, Syniuta S. Young and advanced tumor - some 2D electrodynamic distinctions: Melanoma and satellite during a vascular occlusion test: Feasibility study. Med Biol Eng Comput 2018;56:211-220. https://doi.org/10.1007/s11517-017-1668-0
  28. Babich Y, Nuzdhina M. New Phenomenon in Living Matter?: Clusterization & Synchronization of Electrodynamic Landscape. J Cancer Res Oncobiol 2019;2:15.
  29. Zhang D, Yan X, Zhang X, Liu C, Dang R, Xiao T et al. Synchrotron radiation phase-contrast X-ray CT imaging of acupuncture points. Anal Bioanal Chem 2011;401:803-808. https://doi.org/10.1007/s00216-011-4913-7
  30. Chen CW, Tai CJ, Choy CS, Hsu C, Lin WP, Chiang H et al. Wave-induced flow in meridians demonstrated using photoluminescent bioceramic material on acupuncture points. Evid Based Complement Alternat Med 2013;2013:739293.
  31. Zhang WB, Tian YY, Li H. A discovery of low hydraulic resistance channel along meridians. J of Acup and Merid Studies 2008;1:20-28 https://doi.org/10.1016/S2005-2901(09)60003-0
  32. Kovich F. The Impedance Profile of Acupuncture Points. J Acupunct Res 2018;35:104-107. https://doi.org/10.13045/jar.2018.00080
  33. Zhang WB, Wang GJ, Fuxe K. Classic and Modern Meridian Studies: A Review of Low Hydraulic Resistance Channels along Meridians and Their Relevance for Therapeutic Effects in Traditional Chinese Medicine. Synchrotron radiation phase-contrast X-ray CT imaging of acupuncture points 2015;2015:410979.
  34. Levick R. The influence of hydrostatic pressure on trans-synovial fluid movement and on capsular expansion in the rabbit knee. J Physiol 1979;289:69-82 https://doi.org/10.1113/jphysiol.1979.sp012725
  35. Song X, Zhang W, Jia S,Wang G, Wang S, Lia H. Discovery of low hydraulic resistance channels along meridians in rats. World J Acupunct Moxibustion 2021;31:22-29 https://doi.org/10.1016/j.wjam.2020.11.005
  36. Guo Y, Chen SB, Zhang CX, Wang XY, Miao WF, Shi LP et al. Specific distribution of Ca2+ concentration in acupoints of healthy human bodies. Shanghai Zhen Jiu Za Zhi 2002;21:37-38. [in Chinese].
  37. Wang GJ, Ayati MH, Zhang WB. Meridian studies in China: a systematic review. J Acupunct Meridian Stud 2010;3:1-9. https://doi.org/10.1016/S2005-2901(10)60001-5
  38. Kim BH, On the Kyungrak System. J Acad Med Sci 1963;90:1-41.
  39. McCaig CD. Sinal neurite reabsorption and regrowth in vitro depend on the polarity of an applied electric field. Development 1987;100:31-41. https://doi.org/10.1242/dev.100.1.31
  40. Hung YC, Chen WC, Chang TC. Meridian study on the response current affected by electrical pulse and acupuncture. Nanoscale Res Lett 2020;15;146. https://doi.org/10.1186/s11671-020-03373-2
  41. Soh KS, Kang KA, Harrison D. The primo vascular system, its role in cancer and regeneration. New York (NY): Springer; 2011. p. 235-241.
  42. Choi CH, Soh KS. Study of propagation of Light along an acupuncture meridian. J Optical Soc Korea 2003;7:245-248. https://doi.org/10.3807/JOSK.2003.7.4.245
  43. Schlebusch KP, Maric-Oehler W, Popp FA. Biophotonics in the infrared spectral range reveal acupuncture meridian structure of the body. J Altern Complement Med 2005;11:171-173. https://doi.org/10.1089/acm.2005.11.171
  44. Stefanov M, Potroz M, Kim J, Lim J, Cha R, Nam MH. The Primo Vascular System as a New Anatomical System. J Acupunct Meridian Stud 2013;6:331-338. https://doi.org/10.1016/j.jams.2013.10.001
  45. Kim S, Jung SJ, Cho SY. A method for the observation of the primo vascular system in the thoracic duct of a rat. Evid Based Complement Alternat Med 2013;2013:536560.
  46. Yoo JS, Kim HB, Won N. Evidence for an additional metastatic route: in vivo imaging of cancer cells in the primo-vascular system around tumors and organs. Mol Imaging Biol 2011;13:471-480. https://doi.org/10.1007/s11307-010-0366-1
  47. Chen CW, Tai CJ, Choy CS, Hsu CY, Lin SL, Chan WP et al. Wave-Induced Flow in Meridians Demonstrated Using Photoluminescent Bioceramic Material on Acupuncture Points. Evid Based Complement Alternat Med 2013;2013:739293.
  48. Kim DH, Ryu Y, Hahm DH. Acupuncture points can be identified as cutaneous neurogenic inflammatory spots. Sci Rep 2017;7;15214. https://doi.org/10.1038/s41598-017-14359-z