• Title/Summary/Keyword: Elderly with mild dementia

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The effect of computer based cognitive rehabilitation program on the improvement of generative naming in the elderly with mild dementia: preliminary study (한국형 전산화 인지재활프로그램이 초기 치매노인의 생성 이름대기 수행에 미치는 효과에 관한 예비연구)

  • Byeon, Haewon
    • Journal of the Korea Convergence Society
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    • v.10 no.9
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    • pp.167-172
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    • 2019
  • The purpose of this study was to investigate the effect of computer based cognitive rehabilitation program on the generative naming. Twenty - one patients were assigned to the CoTras program and eight were treated with traditional face - to - face language rehabilitation such as paper and table activities. The experimental group and the control group performed sequential language recall memory training, association memory recall training, language categorization memory training, and language integrated memory training for 12 weeks. The Welch's robust ANCOVA showed significant differences in mean fluency and MMSE-K changes (p<0.05). On the other hand, phonemic fluency increased significantly after 12 weeks of treatment compared to baseline in both experimental and control groups, but there was no statistically significant difference between treatment groups. The results of this study suggest that the computer based cognitive rehabilitation program may be more effective in improving the semantic fluency than the conventional cognitive-linguistic rehabilitation.

Relationship Between Amyloid Positivity and Sleep Characteristics in the Elderly With Subjective Cognitive Decline

  • Kyung Joon Jo;SeongHee Ho;Yun Jeong Hong;Jee Hyang Jeong;SangYun Kim;Min Jeong Wang;Seong Hye Choi;SeungHyun Han;Dong Won Yang;Kee Hyung Park
    • Dementia and Neurocognitive Disorders
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    • v.23 no.1
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    • pp.22-29
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    • 2024
  • Background and Purpose: Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognition and performance of daily activities. Recent studies have attempted to establish the relationship between AD and sleep. It is believed that patients with AD pathology show altered sleep characteristics years before clinical symptoms appear. This study evaluated the differences in sleep characteristics between cognitively asymptomatic patients with and without some amyloid burden. Methods: Sleep characteristics of 76 subjects aged 60 years or older who were diagnosed with subjective cognitive decline (SCD) but not mild cognitive impairment (MCI) or AD were measured using Fitbit® Alta HR, a wristwatch-shaped wearable device. Amyloid deposition was evaluated using brain amyloid plaque load (BAPL) and global standardized uptake value ratio (SUVR) from fluorine-18 florbetaben positron emission tomography. Each component of measured sleep characteristics was analyzed for statistically significant differences between the amyloid-positive group and the amyloid-negative group. Results: Of the 76 subjects included in this study, 49 (64.5%) were female. The average age of the subjects was 70.72±6.09 years when the study started. 15 subjects were classified as amyloid-positive based on BAPL. The average global SUVR was 1.598±0.263 in the amyloid-positive group and 1.187±0.100 in the amyloid-negative group. Time spent in slow-wave sleep (SWS) was significantly lower in the amyloid-positive group (39.4±13.1 minutes) than in the amyloid-negative group (49.5±13.1 minutes) (p=0.009). Conclusions: This study showed that SWS is different between the elderly SCD population with and without amyloid positivity. How SWS affects AD pathology requires further research.

Association between Medial Temporal Atrophy, White Matter Hyperintensities, Neurocognitive Functions and Activities of Daily Living in Patients with Alzheimer's Disease and Mild Cognitive Impairment (알츠하이머병 및 경도인지장애 환자에서 내측두엽 위축, 대뇌백질병변, 신경인지기능과 일상생활 수행능력과의 연관성)

  • An, Min hyuk;Kim, Hyun;Lee, Kang Joon
    • Korean Journal of Psychosomatic Medicine
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    • v.29 no.1
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    • pp.67-76
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    • 2021
  • Objectives : The aim of this study was to compare activities of daily living (ADLs) according to degenerative changes in brain [i.e., medial temporal lobe atrophy (MTA), white matter hyperintensities] and to examine the association between neurocognitive functions and ADLs in Korean patients with dementia due to Alzheimer's disease (AD) and mild cognitive impairment (MCI). Methods : Participants were 111 elderly subjects diagnosed with AD or MCI in this cross-sectional study. MTA in brain MRI was rated with standardized visual rating scales (Scheltens scale) and the subjects were divided into two groups according to Scheltens scale. ADLs was evaluated with the Korean version of Blessed Dementia Scale-Activity of daily living (BDS-ADL). Neurocognitive function was evaluated with the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease assessment packet (CERAD-K). Independent t-test was performed to compare ADLs with the degree of MTA. Pearson correlation and hierarchical multiple regression analyses were performed to analyze the relationship between ADLs and neurocognitive functions. Results : The group with high severity of the MTA showed significantly higher BDS-ADL scores (p<0.05). The BDS-ADL score showed the strongest correlation with the word list recognition test among sub-items of the CERAD-K test (r=-0.568). Findings from the hierarchical multiple regression analysis revealed that the scores of MMSE-K and word list recognition test were factors that predict ADLs (F=44.611, p<0.001). Conclusions : ADLs of AD and MCI patients had significant association with MTA. Our study, which identifies factors correlated with ADLs can provide useful information in clinical settings. Further evaluation is needed to confirm the association between certain brain structures and ADLs.

Reproducing Rhythmic Idioms: A Comparison Between Healthy Older Adults and Older Adults With Mild Cognitive Impairment (리듬꼴에 따른 건강 노인과 경도인지장애 노인의 리듬 재산출 수행력 비교)

  • Chong, Hyun Ju;Lee, Eun Ji
    • Journal of Music and Human Behavior
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    • v.16 no.1
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    • pp.73-88
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    • 2019
  • This research was conducted to compare the rhythm reproduction abilities between older adults with and without mild cognitive impairment (MCI) and analyze the abilities depending on the rhythm idiom. Participants between 60-85 years of age were recruited from senior community centers, dementia prevention centers, and senior welfare centers. A total of 57 participants were included in this study: 27 diagnosed with MCI and 30 healthy older adults (HOA). The experiment was conducted individually in a private room in which a participant was given random binary time rhythm idioms and instructed to reproduce the rhythmic idioms with finger tapping. Each participant's beat production was recorded with the Beat Processing Device (BPD) for iPad. BPD calculated rhythm reproduction as measured through rhythm ratio and error among beats. Results showed marginal differences between the two groups in terms of mean scores of rhythm reproduction abilities. In terms of the rhythm ratio among beats, both groups' highest rhythm reproduction rate was for <♩ ♩>, and their lowest reproduction rate was for <♩. ♪>. In conclusion, there was no significant difference in rhythm reproduction ability between the HOA and MCI groups. However, the study found an interesting result related to performance level of rhythmic idioms. This result provides therapeutic insight for formulating rhythm tasks for older adults.

A Survey on Visiting Nurses' Management for Elders with Cognitive Impairment Living in a Community: Focused on Health Centers in a Metropolitan and Medium-sized Cities (방문간호사의 재가노인 인지기능장애 관리에 대한 실태조사: 광역시보건소와 중소도시보건소를 중심으로)

  • Lee, Chong Mi;Kim, Younkyoung;Park, Inhyae
    • Korean Journal of Occupational Health Nursing
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    • v.23 no.4
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    • pp.197-207
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    • 2014
  • Purpose: The purpose of this study was to investigate the status and characteristics of visiting nurses' management for elders with cognitive impairment living in a community focused on health centers in a metropolitan city and five medium-sized cities. Methods: Data were collected from 47 visiting nurses working in a metropolitan city and 47 visiting nurses working in five medium-sized cities from November to December 2012. Results: There were no statistically significant differences in knowledge, attitudes, and nursing behaviors of cognitive impairment between two groups (F=2.13, p=.148; F=3.64, p=.060; F=0.28, p=.595). Among the elders referred to a physician in a metropolitan city by visiting nurses, 42.4% were diagnosed as mild cognitive impairment and 15.2% were diagnosed as severe dementia. The major intervention programs which visiting nurses currently applied for elders were medication and exercise intervention programs, and the intervention programs which they would want to apply in the future were playing, music and recall intervention programs. Conclusion: The cognitive impairment screening test can be done effectively by visiting nurses. This study also suggests to develop various kinds of intervention programs to improve cognitive function for elders living in a community.

The Healing Effects of the Agro-Healing Program Using Insect Resources (곤충자원을 이용한 농가형 치유농업프로그램의 치유효과 분석)

  • So-Yun Kim;Sun Young Kim;Hyun-Myung Choi;Sangmin Ji
    • Journal of Agricultural Extension & Community Development
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    • v.30 no.1
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    • pp.1-13
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    • 2023
  • This study aims to examine the effect of healing program using insect. For the insect resources, the program uses 3 species of emotional insects. The subjects were a total of 29, the elderly with mild dementia and adults with developmental disabilities in the facility. The activities are 9 programs in total and each program takes 2 hours once a week. For data collection, we measured a blood pressure, stress level using autonomic nervous system activity, and scale of happiness, depression and insomnia by a survey. The datas were collected every week before and after the program. As a result of paired-sample t-test analysis, the participants of the agro-healing program using insects had positive effects as follows: reducing a depression, relieving a symptom of insomnia and stabilizing a blood pressure. Through the results of this study, it was possible to confirm the positive effects of the agro-healing program using insects. If farms lead agro-healing program using insects on their own, it could be expected to contribute to improve the quality of life through agriculture as well as to improve the farms' income.

Investigation of the Correlation between Seoul Neuropsychological Screening Battery Scores and the Gray Matter Volume after Correction of Covariates of the Age, Gender, and Genotypes in Patients with AD and MCI (알츠하이머 치매 및 경도인지기능장애 환자에서 나이, 성별, 유전자형을 고려한 뇌 회백질 부피와 표준신경심리검사와의 상관관계 연구)

  • Lee, Seung-Yeon;Yoon, Soo-Young;Kim, Min-Ji;Rhee, Hak Young;Ryu, Chang-Woo;Jahng, Geon-Ho
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.4
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    • pp.294-307
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    • 2013
  • Purpose : To investigate the correlations between Seoul Neuropsychological Screening Battery (SNSB) scores and the gray matter volumes (GMV) in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) and cognitively normal (CN) elderly subjects with correcting the genotypes. Materials and Methods: Total 75 subjects were enrolled with 25 subjects for each group. The apolipoprotein E (APOE) epsilon genotypes, SNSB scores, and the 3D T1-weighted images were obtained from all subjects. Correlations between SNSB scores and GMV were investigated with the multiple regression method for each subject group using both voxel-based and region-of-interest-based analyses with covariates of age, gender, and the genotype. Results: In the AD group, Rey Complex Figure Test (RCFT) delayed recall scores were positively correlated with GMV. In the MCI group, Seoul Verbal Learning Test (SVLT) scores were positively correlated with GMV. In the CN group, GMV negatively correlated with Boston Naming Test (K-BNT) scores and Mini-Mental State Examimation (K-MMSE) scores, but positively correlated with RCFT scores. Conclusion: When we used covariates of age, gender, and the genotype, we found statistically significant correlations between some SNSB scores and GMV at some brain regions. It may be necessary to further investigate a longitudinal study to understand the correlation.