• Title/Summary/Keyword: Elaeagnus

Search Result 99, Processing Time 0.05 seconds

Efficacy of Elaeagnus umbellata leaves on prevention of cadmium-induced toxicity in HepG2 cells

  • Jae-Yeul Lee;Seun-Ah Yang;Won-Bin Bae
    • Food Science and Preservation
    • /
    • v.30 no.5
    • /
    • pp.797-810
    • /
    • 2023
  • Elaeagnus umbellata leaves have been reported to suppress inflammation, allergic responses, lung cancer proliferation and oral bacterial growth. Cadmium (Cd) is a heavy metal that has been found to cause many toxicities, including liver toxicity. The aim of this study was to evaluate the capacity of 70% ethanol extract of E. umbellata leaves (EUL) to protect human hepatocytes from Cd toxicity. After exposure of HepG2 cells to Cd at 10 𝜇M for 24 h, cell viability, expression levels of apoptosis- and antioxidant-related proteins, reactive oxygen species (ROS) accumulation and Cd uptake were assessed. EUL protected HepG2 cells from Cd-induced apoptosis as determined by MTT assay. A decrease in caspase-3 and p-p53 protein levels was observed in cells pretreated with EUL prior to Cd exposure. Furthermore, the Cd-induced increase in intracellular DCF fluorescence was attenuated by EUL, indicating that the Cd-induced apoptosis preventing effect was associated with the suppression of ROS accumulation. Moreover, EUL's effects on the inhibition of p38, JNK, and AKT phosphorylation also appear to be associated with protection against Cd toxicity. Moreover, EUL upregulated Cd-depressed expression of Nrf2, HO-1, catalase, and MT-1,2 proteins, suggesting that Cd uptake-induced apoptosis in HepG2 cells may be inhibited by EUL's antioxidative potential.

Study on the Antioxidant Activity of Extracts from the Fruit of Elaeagnus multiflora Thunb (뜰보리수(Elaeagnus multiflora Thunb) 추출물의 항산화 효과에 관한 연구)

  • Hong Ju-Yeon;Nam Hak-Sik;Lee Yang-Suk;Yoon Kyung-Young;Kim Nam-Woo;Shin Seung-Ryeul
    • Food Science and Preservation
    • /
    • v.13 no.3
    • /
    • pp.413-419
    • /
    • 2006
  • This study was investigated to analyze the antioxidant activity or extracts form Elaeagnus multiflora Thunb for development to the functional materials. The antioxidative activities of water ethanol and methanol extracts from the Elaeagnus multiflora Thunb were analyzed by electron donating ability (EDA), anti-oxidization activity, superoxide dismutase (SOD)-like activity, The superoxide anion radical-scavenging activity, and nitrite scavenging ability. The Etectron donating ability of methanol extract was higher in 1.0 mg/mL of extraction solution than those of ethers. The anti-oxidization activity of ethanol and methanol extracts by thiocyanate method using linolenic acid system was higher than those of the water extract. The SOD-like activity was increased with increase of the extract concentration in each extracts. The SOD-like activity was highest in 2.0 mg/mL of methanol extract. The superoxide anion radical-scavenging activity was increased with increase of the concentration in the ethanol extract and methanol extract. The nitrite scavenging ability of water extracts in 1.0 mg/mL of extraction soiution in pH 1.2 was higher than ethanol extrats and methanol extracts. The nitrite scavenging ability of all extracts was decreased according to increase of pH.

Changes on the Components of Elaeagnus multiflora Fruits during Maturation (성숙에 따른 뜰보리수(Elaeagnus multiflora) 과실의 성분 변화)

  • Hong Ju-Yeon;Nam Hak-Sik;Kim Nam-Woo;Shin Seung-Ryeul
    • Food Science and Preservation
    • /
    • v.13 no.2
    • /
    • pp.228-233
    • /
    • 2006
  • This study was Carried out to the changes of nutrientd and components for food valuation estimation during maturation of Elaeagnus multiflora fruits. The content of moisture was decreased during maturation, but brix was increased. The content of carbohydrate was increased during maturations but crude protein was decreased. And the content of reducing sugar was increased. The content of free fructose and glucose were high and its content were increased during maturation. Total content of free sugars were 135.66 mg/100 g-fr.wt in mature green fruit, 544.26, 787.83 mg/100 g-fr,wt in mature and over mature fruits, respectively. The Organic acids of Elaeagnus multiflora fruits were acetic, citric lactic, and malic, succinic acids. The content of citric acid was the highest among organic acids. Total content of organic acids were 407.95 mg/100 g-fr,wt in green mature fruits, and were decreased during maturation. The content of reducing vitamin C was 56.98 mg/100 g-fr.wt in mature green fruits and total contents of vitamin C was decreased during maturation. The content of phenol substance was 411.39 mg/100 g-fr.wt in the mature green fruit and was decreased during maturation.

Strategy to Control Surface Fire using Vegetational Fire Breaks in Rangelands of Nilgiris, Southern India

  • Paulsamy, S.;Kil, Bong-Seop;Arumugasamy, K;Padmathy, S.
    • The Korean Journal of Ecology
    • /
    • v.26 no.5
    • /
    • pp.251-254
    • /
    • 2003
  • To control the spread of surface fire in the rangelands and to check the entry of fire into forest systems from grassland patches, 26 evergreen / succulent species were selected and among them 3 shrubby species such as Berberis tintoria Lesch, Elaeagnus kologa Schlecht and Rhodomyrtus tomentosa Wt. were screened for vegetational fire breaks on the basis of leaf moisture content and some other ecological characters. The fire trail experiments indicate that crossing of fire was checked by the fire belt size of 5 ${\times}$ 1.5m for all the three species. However, due to higher fire retardant capacity, the Ire belt of R. tomentosa was effective in comparison to other two species.

A Preliminary Study on Hypocholesterolemic and Hypoglycemic Activities of Some Medicinal Plants

  • Choi, Jae-Sue;Chung, Hae-Young;Young, Han-Suk
    • Korean Journal of Pharmacognosy
    • /
    • v.21 no.2
    • /
    • pp.153-157
    • /
    • 1990
  • Total cholesterol level in mice with hypercholesterolemia was determined after intraperitoneal administration of the methanolic extract of some medicinal plants. From the data obtained, it was suggested that the methanolic extract of Elaeagnus crispa, Ixeris dentata, Prunus davidiana, Eriobotrya japonice, Aralia elata and Phragmites communis produced a significant hypocholesterotemic effect. In the case of the extract of Saussurea diamantiaca, on the other band, the total cholesterol level was markedly increased. The methanolic extract of Ixeris dentata, Prunus davidiana and Phragmites communes also decreased the level of blood glucose in alloxan-diabetic male albino mice while that of Eriobotrya japonica, Allium tuberosum, Houttuynia cordata and Eucommia japonica did not produce this effect.

  • PDF