• 한국의사학회지
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• 제34권2호
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• pp.25-43
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• 2021

Among the ancient ideas of East Asia, there is a myth about the symbol of the Four Gods who commands all directions in the east, south, west, and north, and this is also reflected in the medical field. However, although there is discussion about Qinglong Decoction (青龍湯), Baihu Decoction (白虎湯) and Xuanwu Decoction (玄武湯) in the 『Shanghan Lun (傷寒論)』, there is no content focusing on Zhuniao decoction (朱鳥湯). Considering the consistent perspective of 『Shanghan Lun』, which recognizes the disease-syndrome and seeks prescriptions based on yin and yang thinking, this is very unusual. Therefore, in this study, it was revealed that the concept of 'Sishen Decoction (四神湯)' itself was a concept that emerged when the authors of 『Shanghan Lun』 established the 'eight-principles syndrome differentiation (八綱辨證)' system in their recognition and response to diseases-syndromes. Based on this, I considered the following possibilities: They were able to present Qinglong decoction, Baihu Decoction and Xuanwu decoction, as appropriate prescriptions for 'exterior cold excess syndrome (表寒實證)', 'interior heat deficiency syndrome (裏熱虛證)', and 'interior cold deficiency syndrome (裏熱實證)'. However, it is possible that the name of the prescription 'Zhuniao decoction' was not intentionally used, because it was not possible to provide an appropriate prescription for 'exterior cold excess syndrome (表熱實證)'.

• 대한한의학원전학회지
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• 제28권1호
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• pp.21-34
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• 2015

Objectives : The treatment starts with physical examination. The four examinations(四診) is a method to examine the disease. The books on history of diagnostics about it contained substantial contents about inspection(望診) and palpation including pulse taking(切診), while they contained little contents about auscultation(聞診) and interrogation or questioning(問診) relatively. For this reason, this study was conducted as on interrogation first of all. Methods : I looked into the contents related to interrogation that were scattered in plenty of books. There were chapters of specialty in interrogation since the Ming dynasty, so I looked into these chapters in chronological order. Results & Conclusions : The level of the contents of interrogation prior to the Ming dynasty were rudimentary and recapitulative. However, there was a turning point by three kinds of books appeared in the Ming dynasty. Yixuerumen Wenzheng dealt with detailed contents. Yixuezhunshengliuyao Wenbingbixiang extended the range of contents. Jingyuequanshu Shiwenpian systematized Eight Principle Pattern Identification(八綱辨證) with increase of contents. Since then, books of the Qing Dynasty were mostly based on three kinds of books ahead. Among these, Yimenfalu Yimingwenbingzhifa(醫門法律 一明問病之法) and Xingsewaizhenjianma wenfa(形色外診簡摩 問法) mentioned the importance of a succinct interrogation that hit the mark and Yibian Yiwenzheng dealt with another detailed contents unlike the previous books based on substantial contents.

• 동의생리병리학회지
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• 제22권5호
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• pp.1276-1282
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• 2008

This experiment was designed to investigate the effect of the ODTCMT and DDTCMT extract on protecting microglia and inhibiting acetylcholinesterase and oxidants. The effects of the ODTCMT and DDTCMT extract on cell death of BV2 microglial cell line treated by $IFN-{\gamma}$ ; expression of NO, ROS in BV2 microglial cell line treated by lipopolysaccharide (LPS) ; AChE activity in PC-12 cell treated by NGF were investigated, respectively. The ODTCMT and DDTCMT extract significantly increased cell viability in BV2 microglial cell line treated with $IFN-\nu$. The ODTCMT and DDTCMT extract suppressed the NO and RDS production in BV2 microglial cell line treated by LPS. The ODTCMT and DDTCMT extract groups also showed inhibition of AChE activity in PC-12 cell line. According to the above result, it is suggested that the ODTCMT and DDTCMT extract might be usefully applied for prevention and treatment of Alzheimer's disease. OnDam-TanghapChongMyoung-Tang (ODTCMT), DoDam-TanghapChongMyoung-Tang (DDTCMT), Microglia, acetylcholinesterase, ROS