• Title/Summary/Keyword: Effectiveness Index

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Hydrogel Dressing with a Nano-Formula against Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa Diabetic Foot Bacteria

  • El-Naggar, Moustafa Y.;Gohar, Yousry M.;Sorour, Magdy A.;Waheeb, Marian G.
    • Journal of Microbiology and Biotechnology
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    • v.26 no.2
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    • pp.408-420
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    • 2016
  • This study proposes an alternative approach for the use of chitosan silver-based dressing for the control of foot infection with multidrug-resistant bacteria. Sixty-five bacterial isolates were isolated from 40 diabetic patients. Staphylococcus aureus (37%) and Pseudomonas aeruginosa (18.5%) were the predominant isolates in the ulcer samples. Ten antibiotics were in vitro tested against diabetic foot clinical bacterial isolates. The most resistant S. aureus and P. aeruginosa isolates were then selected for further study. Three chitosan sources were tested individually for chelating silver nanoparticles. Squilla chitosan silver nanoparticles (Sq. Cs-Ag0) showed the maximum activity against the resistant bacteria when mixed with amikacin that showed the maximum synergetic index. This, in turn, resulted in the reduction of the amikacin MIC value by 95%. For evaluation of the effectiveness of the prepared dressing using Artemia salina as the toxicity biomarker, the LC50 was found to be 549.5, 18,000, and 10,000 μg/ml for amikacin, Sq. Cs-Ag0, and dressing matrix, respectively. Loading the formula onto chitosan hydrogel dressing showed promising antibacterial activities, with responsive healing properties for the wounds in normal rats of those diabetic rats (polymicrobial infection). It is quite interesting to note that no emergence of any side effect on either kidney or liver biomedical functions was noticed.

A Study on the Attractions Evaluative Systems of Gyeongju Historic Heritage Sites (경주역사유적지구의 흡인력 평가지표 선정 연구)

  • Yu, Wen-Dong;Kang, Tai-Ho
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.33 no.3
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    • pp.103-113
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    • 2015
  • This study is an evaluation index development research based on Gyeongju Historic Heritage Sites to identify the attractive Properties of Gyeongju, which decided to competitiveness of the historical city. We got the export Indicator candidate groups by the literature reviews and UNESCO, ICOMOS, and 49 Indicator candidate groups had been selected. In the end, we chose 42 attraction indexes in charm of the cultural heritage side, Cultural heritage tourism resources Side, Restraining force Heritage tourism Side three aspects based on the analysis of Importance(M), Standard deviation(SD), Content Validity Ratio(CVR), Agreement, convergence by using Delphi Technique. We can determine these indicators will be useful basic information, for improving the city's historic attractions. In the future, used these indicators as a basis for Attractions effectiveness evaluation of Gyeongju, Through which the attractions of Gyeongju can be re-recognized.

A STUDY ON THE BLEACHING EFFECTIVENESS OF BLEACHING AGENTS AND THE APICAL LEAKAGE ACCORDING TO THE LOCATION OF THE INTRACORONAL BASE (무수치 표백시 표백제의 성분에 따른 표백효과 및 이장재의 위치에 따른 치근부 누출에 대한 실험적 연구)

  • Shin, Jea-Hyun;Kim, Yong-Kee;Hong, Chan-Ui;Shin, Dong-Hoon
    • Journal of the Korean Academy of Esthetic Dentistry
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    • v.4 no.1
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    • pp.12-22
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    • 1995
  • The purposes of this study were to compare the bleaching efficacy of sodium perborate when mixed either with Superoxol or distilled water and to evaluate the efficacy of different location of intracoronal base on the presence of apical leakage of tested bleaching agents. Forty eight extracted human permanent incisors were stained via whole blood and canal fillings with conventional gutta percha were performed after routine biomechanical perparations. The experimental intracoronal base was placed either at the cementoenamel junction(group 3, 4) or 2mm below cementoenamel junction(group 1, 2). Walking bleaching was performed by two different combinations of bleaching agents : sodium perborate with distilled water in group 1, 3 and sodium perbrate with Superoxol in group 2, 4. The roots of the teeth were evaluated for the presence of color change to assess the leakage of bleaching agents and the cervical one-thirds of the crown were evaluated for bleaching effect from the whiteness Indea calculated by spectrophotometer. The results were as follows : 1. At the end of 12 days, all the sample teeth demonstrated the increase of Whiteness Index at cervical 1/3 of crown although there were some minor differences among groups. 2. Regardless of location of the base, sodium perborate with superoxol(group 2, 4) showed better results in bleaching than the sodium perborate with distilled water(group 1, 3). 3. Bleaching agent leaked into the root area when the base was placed 2mm below cementoenamel junction but no leakage was found when the base was placed at the cementoenamel junction.

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The Effect of Diathermy Treatment through Physiotherapist's Hand on the Pain and Disability Index in Chronic Lumbar Pain Patients (물리치료사 손을 통한 고주파치료가 만성요통 환자의 통증과 장애지수에 미치는 영향)

  • Kwon, Kung;Kim, Chan Mun;Park, Shin-Jun
    • Journal of the Korea Convergence Society
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    • v.9 no.2
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    • pp.289-294
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    • 2018
  • A test study was conducted to identify the effects of diathermy through therapist's hand on patients with chronic lumbar pain. The study assessed the effectiveness of Winback High Frequency TECAR Therapy on 21 patients suffering from chronic lumbar pain and the testing was held at H Hospital and began in April 2016 and concluded in September 2016. Assessment of pain relief was through a Visual Analogue Scale (VAS) and the Oswestry Disability Questionnaire (ODQ). The results showed a VAS score decrease from $6.67{\pm}1.76$ to $5.52{\pm}2.03$ (p<0.05) and the ODQ results also showed an decrease from $41.19{\pm}2.56$ to $35.14{\pm}5.11$ (p<0.05). Both of these results are indicative of the positive effects that diathermy through therapist's hand has in the treatment of chronic pain, and the necessity for further studies in this field.

Effect of East-West Integrative Rehabilitation on Activities of Daily Living and Cognitive Functional Recovery in Stroke Patients: A Retrospective Study (뇌졸중 환자의 일상생활 및 인지기능 회복에 대한 의·한의 협진 재활치료의 효과)

  • Moon, Sori;Keum, Dongho
    • Journal of Korean Medicine Rehabilitation
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    • v.30 no.2
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    • pp.105-123
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    • 2020
  • Objectives This study was conducted to verify the effectiveness of east-west integrative rehabilitation therapy on activity of daily living and cognitive functional recovery in stroke patients by comparing with integrative rehabilitation therapy group and conventional rehabilitation therapy group in a single institution. Methods The medical records of 106 stroke patients hospitalized in Department of Rehabilitation Medicine, Dongguk University Bundang Oriental Hospital from January 1, 2017 to February 28, 2019 were reviewed. After screening and dividing it into conventional rehabilitation (CR) group and integrative rehabilitation (IR) group, Korean version of Modified Barthel Index (K-MBI), functional independence measure (FIM), clinical dementia rating-sum of boxes (CDR-SB) were statistically analyzed. Results IR group showed significant improvement in K-MBI, FIM, and CDR-SB after treatment (p<0.001) and there was a statistically significant difference in K-MBI and CDR-SB score changes than CR group (p<0.05). And chronic patient of IR group showed significant improvement in K-MBI, FIM, and CDR-SB after treatment (p<0.01) and there was a statistically significant difference in CDR-SB score changes than CR group (p<0.05). In particular, the earlier the treatment initiation time, the more the improvement in function and when the treatment started within 2 years from the onset and patients took acupuncture and pulsed electromagnetic therapy, all scales significantly improved (p<0.001). Conclusions IR showed more improvement on activities of daily life and cognitive functional recovery than CR in this study.

A comparative study of the clinical effects of PRP and non-absorbable membrane in the treatment of mandibular class II furcations (하악 2급 이개부 병변 치료시 비흡수성 차폐막과 혈소판 농축 혈장의 임상적 효과에 대한 비교 연구)

  • Kim, Chang-Ho;Lim, Sung-Bin;Chung, Chin-Hyung;Hong, Ki-Seok
    • Journal of Periodontal and Implant Science
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    • v.34 no.3
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    • pp.509-522
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    • 2004
  • This study was performed to compare the clinical effectiveness of two regenerative techniques for class II furcation involvements in human: a combination of bone grafts with PRP vs. GTR with bone grafts. The e-PTFE group was treated with non-absorbable membrane and bone grafts, the PRP group was treated with PRP and bone grafts Pocket depth, clinical attachment level, and gingival recession were measured at baseline and postoperative 6 months. Vertical and horizontal furcation depth were measured by re-entry surgeries at 6 months post-treatment Both groups were statistically analyzed by Wilcoxon signed Ranks Test & Mann-whitney Test using SPSS program (5% significance level). The results were as follows: 1. The change of pocket depth, clinical attachment level, vertical furcation depth and horizontal furcation depth in both groups was decreased significantly at 6 months than at baseline. (p<0.05) 2. The change of gingival recession in both groups was increased significantly at 6 months than at baseline. (p<0.05) 3. The change of alveolar crest absorption in both groups was increased at 6 months than at baseline but there were no statistically significant differences. 4. The change of pocket depth, clinical attachment level, vertical furcation depth and horizontal furcation depth in both groups was increased significantly at 6 months, but there were no statistically or clinically significant differences with both groups. 5. The change of gingival recession and alveolar crest absorption in both groups was increased at 6 months, but there were no statistically or clinically significant differences with both groups. In conclusion, the use of bone graft with PRP or GTR technique improved clinical index of the soft and hard tissue in mandibular class II furcation involvement but there were no statistically or clinically significant differences between bone graft with PRP and GTR technique.

Validity Evaluation of Virtual Training in Maritime Safety (해사안전 가상훈련의 유효성 평가)

  • Jung, Jin-Ki;Lee, Hyeop-Woo;Park, Deuk-Jin;Ahn, Young-Joong
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2018.11a
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    • pp.25-26
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    • 2018
  • Virtual training is widely used based on safety and cost efficiency as a way to efficiently train based on virtual reality. In this paper, we propose the implementation and validation evaluation of life safety training, life training in closed area training, initial fire extinguishing training as a virtual training in maritime safety training. Specifically, we discuss how to implement virtual training to meet the goals of each training, and we propose training methods for evaluating trainees' effectiveness when implemented in this manner. The proposed evaluation method can be used as a quantitative evaluation index of the trainee's training assessment of the training and the safety contribution of the training to the evaluation of the training efficienc

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A Study on the Measurement System Design for the Resin Flow and Curing in the Vacuum Assisted Resin Transfer Molding(VARTM) Process Using the Long Period Fiber Bragg Grating (삽입된 장주기 광섬유 격자를 이용한 VARTM 공정에서의 수지이동 및 변형 과정 예측 시스템 설계에 관한 연구)

  • Yoon, Young-Ki;Chung, Seung-Hwan;Lee, Woo-Il;Lee, Byoung-Ho;Byun, Joon-Hyung
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.28 no.5
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    • pp.489-494
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    • 2004
  • Long Period Gratings (LPG) is currently receiving considerable attention because of their consistent measuring results fur pressure, temperature, strain and flow. LPG is easier to prepare and has a high sensitivity compared with Fiber Bragg Gratings (FBG). In addition, this kind of optical fiber sensors could be used for implementations in various structures. In this paper, LPG was used to monitor in situ the resin flow and the curing process in VARTM (Vacuum Assisted Resin Transfer. Molding). In order to demonstrate the effectiveness of the method, FBG is inserted into the glass mat to monitor the resin flow using optical spectrum analyzer (OSA). The curing reactions in VARTM are also observed using the same method. From the results, the attenuation wavelength shift and the loss change of attenuation band can be obtained from the status of the RTM (Resin Transfer Molding) sample owing to the internal variations of the .effective index, temperature, and pressure. It is shown that the proposed LPG is more effective in monitoring the curing reaction than FBG.

Management Planning of Gondola Cars through Efficiency Analysis (효율성 분석을 통한 무개차 운용 방안에 관한 연구)

  • Kim, Kyoung Tae;Lee, Suk;Lee, Young Ho;Yang, Keun Yul
    • Journal of the Korean Society for Railway
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    • v.16 no.2
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    • pp.138-143
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    • 2013
  • Recently, the demand for rail freight has gradually decreased. In particular, the demand in Korea for open freight cars, which classification includes gondola cars, hopper cars and gravel cars has been significantly reduced. The role of gondola cars in the rail transportation market shrank to 14.5% in 2010 from 23.3% in 2001. The transportation demand of gondola cars in the long term is expected to be reduced further. Because some gondola cars have been converted to container cars and various containers are being developed to transport bulk cargo by container cars. However, gondola cars still play an important role in rail freight transport. Therefore, the management planning of gondola cars is needed in order to prepare for the long-term declining demand. In this study, we propose a future direction for the management planning of gondola cars through the effectiveness analysis of gondola cars operation.

The Study on Integrated Teaching and Learning Strategy u-Learning (U-러닝 환경에서의 통합적 수업 전략 연구)

  • Yu, Jeung-A;Han, Sun-Gwan
    • Journal of The Korean Association of Information Education
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    • v.13 no.2
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    • pp.127-134
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    • 2009
  • As wireless-internet and mobile computer revitalizes, various teaching and learning strategies are appearing. In this study, we suggest a new integrated teaching method in u-learning environment effectively. First of all, to apply information technique to education effectively, we grasped various educational factors centered on learners. And then, we categorized them into contents, time and space as three vital factors and analyzed. Next, by combining the important factors, we suggested the new integrated teaching and learning strategy. We also operated personalized the integrated teaching for elementary school students and verified the effect. As a result, we learned that the integrated teaching was effective in the area of higher-level thinking presented as an effectiveness index, learning motivation and self-directed learning. That is, this study will promote excellence in education centered on learners in the hereafter u-learning environment and support general integrated education effectively.

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