• The Journal of the Korea Contents Association
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• v.17 no.1
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• pp.58-68
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• 2017

Atopic dermatitis (AD) is prevalent in preschoolers and schoolchildren. The utilization of complementary and alternative medicine (CAM) is increasing in patients with AD as well as the general population. This study is based on the utilization of CAM for children with AD. Subjects were children suffering from AD who participated in the project of 'Seoul Atopy Asthma Free School'. In 6,800, the number of subject available data to final analysis was 4,985 for children with AD. Independent variables were age, monthly income of households, sleep disturbance, and dependent variables were medical treatment (MT), oriental medicine clinic (OMC), home remedy (HR) use experience during the past 12 months. As a result, MT was 76.5%, OMC was 24.6%, and HR was 62.3%, while multiple treatment from OMC and HR was 34.2%, and MT with OMC and HR was 18.8%. And variables influenced on CAM were age, monthly income of households, and sleep disturbance. However, some parents, tended to recognize that home remedy was effective and safe than other treatments. Therefore, it is recommended to counsel with physician about the merits and demerits of CAM.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.3
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• pp.562-566
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• 2009

The aim of this study was to investigate the effects of herbal remedy using onion (HRO-1) supplementation on body weight change and cholesterol, triglyceride. free fatty acid, total lipid, phospholipid serum level in obesity mice. This study classified 32 of 4 weeks-old male C57BL/6 mice which have obesity caused by high fat fed into four groups of 8 mice and made the subjects medicated them HRO-1 for 6 weeks. Male C57BL/6 mice were divided into four groups; a normal group, a high-fat group, a high-fat group supplemented with HRO-1 (500 mg/kg), a high-fat group supplemented with HRO-1 (1000 mg/kg). In respect to the body weight change, there was statistically significant difference between the HRO-1 (1000 mg/kg) group compared to high-fat group (p<0.05). In the total cholesterol and LDL cholesterol level, there was statistically significant difference between the HRO-1 (1000 mg/kg) group compared to high-tat group (p<0.05). In the triglyceride and free fatty acid level, there was statistically significant difference between the normal group compared to high-fat group (p<0.05). In the total lipid and phospholipid level, there was statistically significant difference between the normal group compared to high-fat group (p<0.05). Also in the total lipid level, there was statistically significant difference between the HRO-1 group compared to high-fat group (p<0.05). The above results suggests that HRO-1 medicated is effective to prevention and treatment of obesity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.6
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• pp.1681-1684
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• 2005

Gastric cancer is the most common disease which is the highest genetic rate, chemotherapy is the only known way to treat, especially advanced gastric cancer. Although, it is the remedy, the harmful side-effects are an obstacle of the sustaining treatment and negative effect on immunologic ability of patients prologed. Consequently, it is surely necessary that effective control for sequele of anti-cancer treatment, and remedy which can improve the quality of patients life. 1, the writer, medicate patients, diagnose as gastric cancer in 4th stage, with Sohap-hyangwon and Chungwoolhyadamjen who complained of pain in sequele of anti-cancer treatment. The size of the metastastic liver tumor is decreasing in patients and the immunologic abilities are maintaining stable. This clinical cases are shown that the oriental medical care in long-term can improve the quality of life of the patients who has sequele of anti-cancer treatment.

• Journal of Families and Better Life
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• v.23 no.4 s.76
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• pp.1-15
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• 2005

Korean society is experiencing rapid changes which are certain to shape the lives of the older people and their families. So, the purpose of this study was to improve the quality of the elderly welfare service in Korea. Even though the interest about the elderly welfare in Korea is rapidly on the increase, the reality of Korean Society still leaves much to be desired, quantitatively as well as qualitatively. Pay attent to this point, now going to grasp the situation of not the handicapped elder people but the general elder people actual life condition and demand for welfare. So this study focused on the demand of not out-of home service but in-home care service. It was based on the data from by Korea National Statistical Office, having observed 6,139 elderly people. The results were as follows. They hope to get the elderly welfare services about health examination service, nursing survice, supporting service for household. That was, the most of them wanted in-home care service than out-of home care service. To ensure effective care to the elderly, it needed development and settlement of welfare service in face of their daily living. And, even though they recognized that they should cover the elderly life expenses themselves, the rate was hit that indicated their adult children as a parents supporter. This means that we should consider not only to the elder people but also to the family which contained the old people as the elderly welfare service. As a remedy, we can find the cooperation between elder welfare service at the social welfare organization and counsel, education at the family strengthen center. To improve the quality of the elderly welfare service in Korea, the elderly welfare service should focus not only on the physical and spiritual health maintenance but also active understanding living environment and growing ability to arbitrate between individual and living.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.16 no.2
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• pp.28-33
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• 2010

Purpose : The purpose of this study is to find out the effects of Joint and Muscle Mobilization applied to the patients with Degenerative Disc Disease by measuring, assessing and analyzing the changes on pain and in flexibility before and after Joint and Muscle Mobilization. Method: Surveyed from June. 2008 to July. 2009 were 10 patients suffering from DDD. Joint and muscle Mobilization were applied for 15 minutes in total. After Joint Mobilization, the Oswestry Disability Index(ODI), Visual Analogue Scale (VAS) were used to measure the degree of the pain on the patients. After Joint and Muscle Mobilization, Spinal-$Mouse^{(R)}$ were used to measure the degree of the flexibility on the patients. Result: 1. There was significant decrease in the numerical values of the VAS & ODI after Joint and Muscle Mobilization (p<0.01). 2. There was significant decrease in the degree of the pain on the patients after Joint and Muscle Mobilization (p<0.01). 3. From the analysis into DDD in the degree the pain before and after Joint and Muscle Mobilization with Paired Sample T-test, It became evident that the longer the period of treatment was, the higher the pains decreases drastically, while significant difference was shown in the flexibility and the degree of the pain (p<0.01). Conclusion: Summed up, it can be generally concluded that Joint and Muscle Mobilization is an effective treatment to rid the patients with DDD of pains safely and promptly. It is, therefore, suggested to continue and expand the study on the cure of DDD and to motivate patients. Joint and Muscle Mobilization is considered as safest and most efficient pain remedy.

• Journal of Pharmaceutical Investigation
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• v.9 no.4
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• pp.13-22
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• 1979

Panax Ginseng C. A. Meyer which has been known for more than 2000 years, occupies a particular place in folk medicine as so called tonic remedy. The brief pharmacological action of Ginseng complied from the numerous reports can be summarized as adaptogenic effect to be increased nonspecific resistance. Among the various components of Ginseng, the effective components has been known Ginseng butanol fraction as so called Ginseng saponin. In order to study on the effect of the Ginseng butanol fraction which influences spontaneous activity by CNS drugs in mice. Experiment of response was measured the change of spontaneous activity by CNS drugs in which mice were treated Ginseng butanol fraction. A method of measuring spontaneous activity in mice used by counting the number of times which were interrupted a beam of light. Results of experiment can be summarized as follows: 1. In case of administrating Ginseng butanol fraction for 1 day, stimulating effect of Ginseng was observed in spontaneous activity by caffeine in comparison with the control. at the first, but after 45 minutes no significant change was observed. 2. In case of administrating Ginseng butanol, fraction for 5days, decreasing tendency was observed in spontaneous activity by caffeine. 3. In case of administrating Ginseng butanol fraction for 10days, marked decrease was observed in spontaneous activity by caffeine in comparison with the control. From the experiment on the increased dose of caffeine, nonsignificant change was observed in comparison with caffeine and sodium benzoate 25mg/kg group. 4. A state of increased resistance was lasted until 5 days, and after 10 days it was disappeared. 5. Otherwise, nonsignificant change was observed for chlorpromazin HCl in comparison with the control. 6. From this result, 10 days administrating of ginseng butanol fraction appeared to have increased resistance in mice against caffeine.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.9
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• pp.2013-2018
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• 2011

Coronary angioplasty and coronary artery bypass graft, both are for the treatment of myocardial infarction widely used methods. For these procedures, there are especially difficulties in stenosis of blood vessels to diagnose accurately. To remedy this problem, by several researchers by using edge detection to detect stenosis of blood vessels has been studying. However, the results of using these methods vary defend on the vascular structure and the quality of the image. In this study, to improve these problems, the new algorithm is proposed. The proposed algorithm consists of methods to detect bifurcation of blood vessels and its ending point by using multi sampling, threshold and fuzzy algorithm. To evaluate the performance of the proposed algorithm, angiography was used for the different results of the blood vessels of the proposed algorithm, and the result was effective in detecting bifurcation of blood vessels and its ending point.

• The Journal of Korean Medicine
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• v.27 no.4
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• pp.74-83
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• 2006

Ssanghwatang (SHT) has been known to prove effective in the treatment for erectile dysfunction (ED), and its modified formula is widely used in clinical practice. However, its fundamental mechanism of action is not clearly known. It is well known that endothelial cells can achieve the relaxation of vascular smooth muscles by the release of nitric oxide (NO). NO is synthesized by the enzyme NO synthase (NOS) from L-arginine and oxygen. It is widely accepted that NO plays an important role in the relaxation of corpus cavernous smooth muscle and vasculature. In addition, in terms of the penile erection, the NO/cGMP pathway is more potent than the PCE1/cAMP pathway. The main purpose of the present study was to investigate the mechanism of the erectile effects of SHT by focusing on its direct effects on corpus cavernous smooth muscle cells. We investigated the NOS activity, nitrite concentration and cGMP levels in rat corpus cavernous smooth muscle cell lines activated by SHT extracts. Furthermore, we evaluated the effect of SHT extracts on penile smooth muscle relaxation following oral administration of SHT extract powder to rats by the dosage of 1 g/kg over fifteen days. As a result, we found that SHT stimulated NO release. NOS activity and cGMP levels were increased by SHT respectively. Furthermore, SHT relaxed the corpus cavernous smooth muscle. These results are consistent with the concept that penile erection by SHT is carried out through the NO/cGMP pathway. In conclusion, the present study shows that SHT increases the NOS activity, synthesizes NO and augments the cGMP, which mediates penile erection. Further determination of the SHT mechanism related with the NO/cGMP pathway strongly indicates that SHT can be used as a remedy for erectile impotence.

• The Journal of Korean Medicine
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• v.27 no.4
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• pp.30-47
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• 2006

Objective : The present study is aimed to elucidate the effects of Cirsium japonicum var. ussuriense on immunomodulation and the potential as an herbal remedy for cancer treatment. Method : It was performed through measurement of effects Cirsium japonicum var. ussuriense extract (CJE) on NO production, NK cell cytotoxicity and cytokine gene expressions related with macrophage and NK cell activity. Result : 1. CJE did not show any direct cytotoxic effects on 7250, HT1080, Hep G2 and CT-26 cells. 2. CJE activated macrophages partially to product NO and up-regulated gene expressions for iNOS in RAW 264.7 cells. 3. CJE promoted cytotoxicity of NK cells against YAC-1 cells at higher concentration than 200 ${\mu}g/ml$. 4. CJE up-regulated gene expressions for $IL-1{\beta}$, IL-2, iNOS, $IFN-{\gamma}$ and $TNF-{\alpha}$ in mice splenocytes.　５. CJE inhibited lung tumor metastasis induced by CT-26 cell transplantation compared with the control group.　Conclusion : It could be concluded that CJE is an effective herbal drug for immune modulating and anti-cancer treatment by promoting activity of macrophages and NK cells.

• The Journal of Korean Medicine
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• v.28 no.3 s.71
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• pp.86-99
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• 2007

Objectives : Cancer patients who are afraid of unpleasant therapy and doubt a perfect cure often seek out traditional Korean medicine or many other kinds of complementary and alterative medicine (CAM) instead. This study was carried out in order to learn the prevalence and kinds of the traditional Korean medicine and CAM to evaluate awareness of and attitude toward it. Methods : 213 patients with gastric cancer who had undergone surgery in the department of gastrointestinal surgery and visited for routine follow-up from November to December of 2004 were included. A questionnaire survey was done by trained interviewers for CAM and demographic information. Results : 96.7% of patients had experience with CAM. The kinds and frequencies of CAM were diet and nutrition 21.0%, folk remedy 21.0%, pharmacological treatment 13.5%, oriental medicine 5.3% and mind-body intervention 1.4%. 56.8% of patients had experienced 2-6 kinds of CAM, 37.4% more than 7. Among diet and nutrition, ginseng (62.9%) was highest, followed by ox leg bone soup (50.8%) and pumpkin (31.5%). Among the folk remedies, elm tree was highest at 46.5%, followed by phellinus linteus (Sang-Whang) at 26.8% and ganoderma lucidum (Young-Gee) 20.7%.satisfaction with CAM was relatively low (43.2%), many patients (78.2%) replied that they would use it continuously. Conclusion : Most patients had experience with many kinds of CAM, but didn't discuss it with medical doctors. If scientific study proves whether or not each kind of CAM is actually effective ondisease, it will help to improve the health of patients and prevent the inappropriate usage and cost.