• Journal of the korean Society of Automotive Engineers
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• v.13 no.6
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• pp.101-108
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• 1991

During torsional fatigue of externally cracked cylindrical specimen, crack face rubbing may occur. At this time, normal contact forces arise when shear displacements cause the crack faces to be wedged open due to mismatch of the fracture surface asperities. These normal forces, in turn, generate friction force which act in opposition to the applied shear stresses and reduce the effective stress intensity factor. The premise of the proposed work is that friction and wedging can be studied by measuring the shear and normal displacement across the crack mouth. We have measured the crack mouth compliance using the new biaxial extensometer.

• International Journal of Naval Architecture and Ocean Engineering
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• v.7 no.5
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• pp.805-816
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• 2015

In the present study, external restraints imposed normal to the plate during the cooling stage were determined to be effective for reduction of the angular distortion of butt-welded or fillet-welded plate. A welding analysis model under external force during the cooling stage was idealized as a prismatic member subjected to pure bending. The external restraint was represented by vertical force on both sides of the work piece and bending stress forms in the transverse direction. The additional bending stress distribution across the plate thickness was reflected in the improved inherent strain model, and a set of inherent strain charts with different levels of bending stress were newly calculated. From an elastic linear FE analysis using the inherent strain values taken from the chart and comparing them with those from a 3D thermal elasto-plastic FE analysis, welding deformation can be calculated.

• Journal of Society of Preventive Korean Medicine
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• v.8 no.2
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• pp.141-156
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• 2004

Objectives : JianTeng-Yuan(交藤圓) is said to be a prescription for preservation of health in ${\ulcorner}$HuaTuo ZhongZangJing(華陀 中藏經)${\lrcorner}$. It is known to have the effect of Bu-Shen(補腎: strengthening kidney) and Yi-Shou(益壽: prolonging the span of one's life). This study investigates whether JTY is effective on inhibition of oxidation stress. Methods : Sprague-Dawley Rats(12-week-old, weight $300{\pm}20g$) were divided into 3 groups. Normal group(n=8) was injected PBS(1ml/body, s.c) at the back neck's skin. Control group(n=8) was injected D-galactose(50mg/kg, 1ml PBS/body, s.c) to induce pathological animals. JTY group was injected the same treatment for the Control group, and fed containing JTY(10%). The whole groups were treated 1 time per day for 6 weeks. After rats were sacrificed and anti-oxidant enzyme(SOD, CAT, G-px) activity, GSH quantity of RBC and tissue(heart, liver and kidney), plasma Vit-C quantity were examined. Besides, the MDA levels of liver and kidney, lipofuscin of heart and endurance of erythrocyte membrane were measured. Results : In the JTY group, RBC's SOD activity decline was halted by 21% of the normal level, compared to the control group ; G-px activity(unit/g of Hb) increased significantly, compared to the normal group ; and the level of Vit-C in plasma increased by 16%. Heart's SOD activity was kept at the same level as that of the normal group ; and CAT activity decline was halted by 26%. Kidney's CAT and G-px activities were kept at the same level as that shown in the normal group, implying the existence of halting effect. Liver also showed a slight halting effect against the decline of anti-oxidant ability, but the effect was not significant(a=0.05). A comparison between the levels of peroxide in SD rats showed that the level of TBARS in plasma increased significantly in the control group and that it was normal in the JTY group. The livers in the JTY group, compared to those in the control group, showed 36% halting effect of the normal level while their kidney's indicated the level significantly lower than the normal level. Heart's lipofuscin increased significantly in the control group, but was alike in both the JTY and the normal groups. Endurance of erythrocyte membrane(%) decreased significantly in the control group while it was kept at the similar level in both the JTY and the normal groups, indicating the halting effect. Conclusions : This study suggests that JTY is effective to defend oxidation stress caused by D-galactose in the animals. It showed that the anti-oxidant ability was maintained and strengthened. On the other hand, it reduced the level of peroxide in animals. In sum, JTY appeared to have the equilibrium normal physiological function in SD rat.

• Journal of Pharmacopuncture
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• v.18 no.4
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• pp.12-19
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• 2015

Objectives: This study was done out to evaluate the effects of Sida rhombifolia methanol extract (SRM) on diabetes in moderately diabetic (MD) and severely diabetic (SD) Sprague-Dawley rats. Methods: SRM was prepared by soaking the powdered plant material in 70% methanol and rota evaporating the methanol from the extract. Effective hypoglycemic doses were established by performing oral glucose tolerance tests (OGTTs) in normal rats. Hourly effects of SRM on glucose were observed in the MD and the SD rats. Rats were grouped, five rats to a group, into normal control 1 (NC1), MD control 1 (MDC1), MD experimental 1 (MDE1), SD control 1 (SDC1), and SD experimental 1 (SDE1) groups. All rats in the control groups were administered 1 mL of distilled water (DW). The rats in the MDE1 and the SDE1 groups were administered SRM orally at 200 and 300 mg/kg body weight (BW), respectively, dissolved in 1 mL of DW. Blood was collected initially and at intervals of 1 hour for 6 hours to measure blood glucose. A similar experimental design was followed for the 30-day long-term trial. Finally, rats were sacrificed, and blood was collected to measure blood glucose, lipid profiles, thiobarbituric acid reactive substances (TBARS) and reduced glutathione (GSH). Results: OGTTs indicated that two doses (200 and 300 mg/kg BW) were effective hypoglycemic doses in normal rats. Both doses reduced glucose levels after 1 hour in the MDE1 and the SDE1 groups. A long-term trial of SRM in the MD group showed a reduced glucose level, a normal lipid profile, and normal GSH and TBARS levels. In SD rats, SRM had no statistically significant effects on these parameters. Normal weight was achieved in the MD rats, but the SD rats showed reduced BW. Conclusion: The study demonstrates that SRM has potential to alleviate the conditions of moderate diabetic, but not severe diabetes.

• Journal of the Korean Institute of Gas
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• v.17 no.1
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• pp.73-80
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• 2013

This study presents sealing behavior and endurance safety of V-grooved o-rings as functions of a strain, compression stress, and contact normal stress using a FEM technique. The FEM results on the sealing behavior and endurance safety show that the maximum strain, maximum compression stress, and maximum contact normal stress of V-grooved o-rings are approximately 1.2 times higher than those of conventional solid o-rings. This is why that an o-ring has a V-groove in the center between two overlapped circles, which is very effective in sealing for ball valves, pressure vessels, and gas equipment. And the extrusion failure in V-grooved o-rings does not take place under an increased gas pressure due to a V-groove. This may extend sealing life compared with that of a conventional solid o-ring.

• Journal of the Korea Convergence Society
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• v.10 no.12
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• pp.517-523
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• 2019

The aim of the study was to examine the effects of the five-sensory horticulture therapy on perceived stress and HRV in adults with depression. The participants were 26 (experimental group=13, control group=13) adult with depression and enrolled in the Regional C mental health welfare center from April to June 2018. The experimental group participated in a total of 8-session five sensory horticultural therapy once a week, and the control group provided horticultural therapy once to the desired subjects after the program. The data were analyzed using descriptive statistics, t-test, and Mann-Whitney U test. There were statistically significant change in perceived stress (t = 3.11, p = .005), LF (t = -3.39, p = .002) and SDNN (t = -2.48, p = .025) in experimental group compared to the control group. Therefore, this therapy was effective for reduction of stress among individuals with the depressive disorder.

• Food Science and Biotechnology
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• v.16 no.6
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• pp.967-974
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• 2007

The present work is aimed to evaluate the protective effect of glutathione-enriched Saccharomyces cerevisiae FF-8 strain on carbon tetrachloride ($CCl_4$)-induced hepatotoxicity and oxidative stress in rats. The activities of liver markers (alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase), lipid peroxidative index (thiobarbituric acid-reactive substances), and the antioxidant status (reduced glutathione) were used to monitor those protective roles of FF-8 strain. The liver marker enzymes in plasma and the lipid peroxidation in the liver were increased when $CCl_4$ was treated but these were significantly decreased by FF-8 strain treatment. The hepatic concentration of glutathione in the current glutathione-enriched FF-8 strain fed animal was approximately twice as high as the normal, but this was slightly increased in response to $CCl_4$ plus glutathione-enriched FF-8 strain. The increased liver triglyceride concentration due to the $CCl_4$ treatment was significantly decreased by FF-8 strain and the reduced level reached to that of normal group. Administration of FF-8 strain in normal rat did not show any signs of harmful effects. Therefore, the current findings suggest that FF-8 strain could be an effective antioxidant with no or negligible side-effects and it might be useful for the purpose of protection treatment of hepatotoxicity and oxidative stress in $CCl_4$-treatment in rat.

• Computers and Concrete
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• v.29 no.2
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• pp.81-92
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• 2022

The influence of normal stress perpendicular to the potential shear plane was always neglected in existing researches, which may lead to a serious deviation of the shear strength of concrete members in practice designs and numerical analyses. In this study, a series of experimental studies are carried out in this paper, which serves to investigate the shear behavior of concrete under compression shear loading. Based on the test results, a three-phase shear failure model for cohesive elements are developed, which is able to take into consideration the influence of normal stress on the shear strength of concrete. To identify the accuracy and applicability of the proposed model, numerical models of a double-noted concrete plate are developed and compared with experimental results. Results show that the proposed constitutive model is able to take into consideration the influence of normal stress on the shear strength of concrete materials, and is effective and accurate for describing the complex fracture of concrete, especially the failure modes under compression shear loadings.

• Journal of Korean Society of Steel Construction
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• v.18 no.2
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• pp.203-211
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• 2006

This paper presents a new, effective torsional constant for thin-waled open beams under concentrated and uniformly distributed torques. The proposed constant can be used directly, instead of the St. Venant torsional constant, for any generic comemrcial finite-element program, without modifying the algorithm. The derived torsional constant accounts for both the pure torsion and the warping torsion, and is equal to the St. Venant torsion constant times a correction factor. It is also shown, in the case of the St. Venant torsion, that the derived constant is identical to the torsional constant. The derived effective torsional constant is different from the one given by Elhelbawey et al. The pure torsional shear stress, the warping shear stress, and the warping normal stress were also determine d, using the maximum twisting angle. The accuracy of the proposed torsional constant was validated by comparing the numerical results with the closed-form solutions or other numerical results available in the literature.

• Proceedings of the KSME Conference
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• 2004.11a
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• pp.220-225
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• 2004

The mesh-insensitive structural stress procedure by Dong is modified to apply to the welded joints with local thickness variation and inignorable shear/normal stresses along local discontinuity surface. In order to make use of the structural stress based K solution for fatigue correlation of welded joints, a proper crack growth model needs to be developed. There exist some significant discrepancies in inferring the slope or crack growth exponent in the conventional Paris law regime. Two-stage crack growth model was not considered since its applications are focused upon the fatigue behavior in welded joints in which the load ratio effects are considered negligible. In this paper, a two-stage crack growth law considering high mean loading is proposed and proven to be effective in unifying the so-called anomalous short crack growth data.