• Title/Summary/Keyword: Effective intervention

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A Randomized, Double-blind, Placebo-controlled Study to the efficacy and Safety of NMED-01 and NMED-02 in Mild Alcoholic Liver Subjects (NMED-01과 NMED-02의 간기능 개선에 대한 인체 효능 평가)

  • Park, Sangwoug;Kwon, Yongbeom;Kim, Ki Tae;Shin, Seon Mi;Leem, Kang-Hyun;Ko, Heung;Song, MiKyung;Jung, Yoon Chul;Kim, Hocheol;Park, Juyeon
    • The Korea Journal of Herbology
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    • v.28 no.6
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    • pp.31-38
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    • 2013
  • Objectives : The purpose of this study was to determine whether NMED-01 or NMED-02 improves laboratory test results in participants with liver function disorder. Methods : This is a randomized, placebo-controlled trial in which participants, treating physicians and data management staff were blinded to treatment group. The study was conducted at Semyung university oriental medicine hospital in Jecheon where participants with high level of serum ${\gamma}$-GTP (60-350 U/L) were enrolled. The intervention consisted of three times daily ingestion of either two capsules of placebo, NMED-01 (NeuMed. co. ltd., Seoul), or NMED-02 (NeuMed. co. ltd., Seoul) for twelve weeks. To evaluate the efficacy and safety of NMED-01 and NMED-02, we primarily evaluated the degree of decrement of serum ${\gamma}$-GPT level among three groups. Secondarily the decrement of serum ALT, AST, and triglyceride level in each group were also evaluated. Adverse effects were monitored during the twelve weeks treatment. Results : The change of ${\gamma}$-GTP level of NMED-01 group was lower than that of placebo group at the end of 12-week administration ($28.1{\pm}38.7U/L$ vs. $9.3{\pm}27.0U/L$, p=0.046). Other variables including AST, ALT, and triglyceride level were not significantly reduced. The decrement of ${\gamma}$-GPT, AST, ALT, and triglyceride level of NMED-02 group was not significant. There were no significant adverse effects or toxicities during treatment period. Conclusions : Participants receiving NMED-01 had improvement in laboratory test results. Despite a modest sample size, our results suggest that NMED-01 are safe and may be potentially effective in improving liver function. However, NMED-02 have lack of a detectable effect in this study.

The Influence of Mental Health Characteristics upon Drinking and Smoking in Adolescents of Capital Area and Non-capital Area (수도권과 비수도권 청소년들의 정신건강 특성이 음주, 흡연에 미치는 영향)

  • Kim, Hwan-Hui
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.5
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    • pp.175-188
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    • 2021
  • The purpose of this study was to grasp the influence of mental health upon the lifelong drinking experience in adolescents of non-capital area and capital area through using the 2019 Youth Health Behavior Survey Data. The research subjects included total 57,303 adolescents who participated in the survey among 60,100 adolescents at totally 800 schools with 400 middle schools and 400 high schools. Out of these, 29,384 middle school students and 27,919 high school students were selected. As a result of the research, the mental health that has significant influence upon the lifelong drinking and smoking experience in case of non-capital area appeared to be significant in the perceived subjective health (p<.01), cognitive stress(p<.001), relief from fatigue(p<.001), sadness & despair experience(p<.001), suicide ideation(p<.001), suicide plan(p<.01), and suicide attempt(p<.001). In case of capital area, the mental health of having a significant impact on the lifelong drinking and smoking experience was indicated to be significant in cognitive stress(p<.01), relief from fatigue(p<.001), sadness & despair experience(p<.001), suicide ideation(p<.001), and suicide attempt(p<.001). Based on this outcome, adolescents' drinking problem has influence upon mental health characteristic. Hence, an effort is needed for developing the intervention & education program aiming at the more effective youth drinking prevention through establishing direction and revaluing education program in consideration of mental health factors by region in adolescents of capital area and non-capital area.

The Effect of Abdominal Draw-in Maneuver with Leg Movements on Transversus Abdominis Thickness and Trunk Control in Stroke Patients (다리 움직임을 동반한 복부 드로우-인 기법이 뇌졸중 환자의 배가로근 두께와 몸통 조절에 미치는 영향)

  • Kang, Jeong-Il;Moon, Young-Jun;Jeong, Dae‐Keun
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.8
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    • pp.287-294
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    • 2020
  • The purpose of this study was, base on the observation that the leg movement has effect on muscles around trunk, to provide clinical fundamental data to develop effective abdominal draw-in technique by investigating the effect of abdominal draw-in exercise accompanying leg movement on the thickness of transversus abdominis muscle and trunk control ability in patients with stroke. The subjects were assigned randomly to experimental group I (n=9) on which the abdominal draw-in technique is applied and experimental group II (n=9) on which the abdominal draw-in technique accompanying leg movement is applied. The thickness of transversus abdominis muscle in the affected side and the trunk control ability were measured before and after treatment using ultrasonography and trunk impairment scale. A session of 30 minutes per day were performed four days a week for four weeks and the measured outcomes were analyzed. The in-group comparison showed significant difference both thickness of transversus abdominis muscle during abdominal draw-in technique application (p<0.01) and trunk control ability (p<0.001) between before and after treatment. The significant difference between two groups were observed only in trunk control ability (p<0.05). It was concluded that the abdominal draw-in technique accompanying leg movement is an intervention that has positive effect not only on transversus abdominis muscle but also on tunk control ability by inducing more efficient contraction reaction in muscles around trunk through autonomic pelvic movement caused by leg movement.

A Study on the Development and Application of Korean Medical Critical Pathway of Lumbar Disc Herniation in Four Different Medical Associations (요추 추간판 탈출증의 4종 한의표준임상경로(CP) 개발 및 시범적용 연구)

  • Kim, Jung-Hyun;Chae, Sang Yeup;Ko, Min-Jung;Jo, Min-Gi;Jang, Jun-Yeong;Kim, Jun Yeon;Kim, Ha-Na;Park, Kyeong Ju;Hwang, Ji-Min;Goo, Bonhyuk;Park, Yeon-Cheol;Baek, Yong-Hyeon;Nam, Sang-Soo;Seo, Byung-Kwan
    • The Journal of Korean Medicine
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    • v.42 no.3
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    • pp.1-8
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    • 2021
  • Objectives: A critical pathway defines the optimal care process, sequencing and timing of intervention by multi-disciplinary health care teams for a particular diagnosis and procedure. It plays an important role as a cost-effective health care delivery system and a tool for quality control of medical and dental services by means of standardizing medical practices. The aim of this study is to investigate the satisfaction of patients and medical staff after implementation of a critical pathway for Korean medical treatment of lumbar disc herniation in integrative medical. Methods and Results: The pre-critical pathway group included 3 patients who underwent the implementation procedure from October 2020. All three patients have successfully been applied critical pathways during inpatient and outpatient treatment. Additionally, medical staff members were satisfied with the usefulness of the critical pathway. Conclusions: The implementation of critical pathway for the Korean medical treatment with lumbar disc herniation in integrative medical hospital can appraise possible applicability in actual clinical field.

Relationship between Levels of Problem Gambling and Stress among Gambling Addicts: The Multiple Mediation Effects of the Basic Psychological Needs (도박중독자의 문제도박 수준과 스트레스와의 관계: 기본심리욕구의 다중매개효과)

  • Kim, Jae-Hwan;Jang, Sung-ho;Shin, Sung-man
    • Korean Journal of Culture and Social Issue
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    • v.28 no.1
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    • pp.43-59
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    • 2022
  • This study conducted a multiple mediation analysis using sub-factors of basic psychological needs (BPNs) as mediators in the relationship between problem gambling and stress of gambling addicts to confirm that BPNs and stress, which affect gambling addiction, may be the result of problem gambling and to find effective intervention strategies. A total of 206 adults gambling addicts were screened by using CPGI. Descriptive statistics, correlation, hierarchical regression, and mediation analysis were conducted. Hierarchical regression analysis results yielded that problem gambling and sub-factors of BPNs were significant predictors of stress when controlling for gender and debt. The sub-factors of BPNs mediated the relationship between problem gambling and stress. These results indicated that BPNs and stress are not only the causes of gambling addiction but also the results from the harmful consequences of gambling addiction. The study supported the possibility of the psychological process of "Deficits of BPNs (of gambling users) → stress (of gambling users) → problem gambling → gambling addiction (of gambling addicts) → problem gambling → Deficits of BPNs (of gambling addicts) → stress (of gambling addicts)" among the variables and provided clinical implications for problem gambling counseling. Lastly, the limitations of this study and suggestions for further study were discussed.

Analysis of Twitter Post with 'Self-Iinjury' and 'Ssuicide' Using Text Mining (텍스트 마이닝기법을 활용한 '자해' 및 '자살' 관련 트위터 게시물 분석)

  • Yuri Lee;Hoin Kwon
    • Korean Journal of Culture and Social Issue
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    • v.29 no.1
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    • pp.147-170
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    • 2023
  • This study explored keywords and key topics by collecting posts related to 'self-Iinjury' and 'suicide' through Twitter. The study subjects were selected as posts containing related hashtags related to self-injury and suicide from October 29, 2019 to November 30, 2020. Text mining based on collected posts resulted in a total of 11 key topics: -6 related to 'self-Iinjury' and 5 related to 'suicide'. The main message in the topic is as follows. First, looking at the main messages contained in the topic, they honestly expressed self-harm and suicide experiences that are difficult to express offline online, and used SNS as a channelpath for requesting help requests. Second, there were common and discriminatory characteristics in posts related to 'self-Iinjury' and 'suicide'. Although topics related to 'self-Iinjury' mainly revealed emotional control and interpersonal functions of self-harm, messages related to 'suicide' showed more clearly messages about suicide prevention addressing and social problems. These results are meaningful in that they can understand the opinions of people who have experienced self-harm and suicide accidents and the public voice on self-harm and suicide-related issues could be better understood, and that this study seeks for effective self-harm and suicide prevention and intervention measures for self-harm and suicide issues.

Effects of a Portable Computerized Cognitive Training System on the Visual-perceptual Function of Stroke Patients with Mild Cognitive Impairment : A Pilot Study (휴대용 전산화 인지훈련 시스템이 경도인지손상이 있는 뇌졸중 환자의 시지각에 미치는 효과)

  • Jeon, Min-Jae;Moon, Jong-Hoon
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.8
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    • pp.603-610
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    • 2019
  • This pilot study investigated the effects of a portable computerized cognitive training system on the visual-perceptual function of stroke patients with mild cognitive impairment. Subjects were twelve stroke patients with mild cognitive impairment, who were assigned to an experimental group (n=6) or a control group (n=6). All subjects were trained in their respective groups for 30 min/day, five times a week, for four weeks. In each session, the experimental group received a portable computerized cognitive training program, and the control group received conventional cognitive training. The Motor-Free Visual Perception-3 (MVPT-3) was used to measure subjects' visual-perceptual ability. The MVPT-3 total scores for both groups significantly improved after the intervention (p<.05). The total score on the MVPT-3 and the score on the visual short-term memory subcategory of the MVPT-3 significantly improved for the experimental group compared to the control group (p<.05). These findings suggest that the portable computerized cognitive training system might be effective to improve the visual-perceptual function of stroke patients with mild cognitive impairment.

The Effects of Computer-Based Cognitive Rehabilitation and Traditional Cognitive Training on the Working Memory and Executive Function in Patients with Mild Traumatic Brain Injury (전산화 인지재활과 전통적 인지훈련이 경도 외상성 뇌손상 환자의 작업기억과 실행기능에 미치는 영향)

  • Moon, Jong-Hoon;Yang, Seung-Bum;Jeon, Min-Jae
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.6
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    • pp.277-286
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    • 2019
  • The aim of this study was to investigate the effects of computer-based cognitive rehabilitation and traditional cognitive training on the working memory and executive function of patients with mild traumatic brain injury. The sample consisted of 20 patients with mild traumatic brain injury who had received rehabilitation treatment in a rehabilitation unit. The subjects were assigned to either the experimental (n = 10) or control group (n = 10). The experimental group received computer-based cognitive rehabilitation and traditional cognitive training for 60 minutes, whereas the control group received only traditional cognitive training for 60 minutes. Both the groups received their respective interventions for 60 minutes a day and 5 times per week across a period of 4 weeks. Working memory and executive function were assessed using the digit span test (forward and backward), visual memory 1 and 2 of the Motor-free Visual Perception Test-3, trail making test, and Stroop test (A and B) both before and after the intervention. The experimental group showed a significantly greater improvement in visual memory and performance on the Stroop test A than the control group. These findings suggest that computer-based cognitive rehabilitation and traditional cognitive training are more effective in promoting positive changes in the working memory and executive function of individuals with mild traumatic brain injury than traditional cognitive training.

The Effect of Emotional Intelligence, Empathy Ability and Calling Consciousness of Nursing Students on Happiness (간호대학생의 감성지능, 공감능력 및 소명의식이 행복에 미치는 영향)

  • Kang, Hye-Seung;Lee, Hyun-Ji;Park, Bo-Ha;Lee, Yeon-Gyeong
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.2
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    • pp.243-252
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    • 2019
  • The purpose of this study was to evaluate the effect of emotional intelligence, empathy ability, and calling consciousness of nursing students on happiness. The survey was conducted 217 nursing students attending in G city from September 3th to September 14th, 2018. Data was collected from self-administered questionnaires about happiness, emotional intelligence, empathy ability and calling consciousness. Data were analyzed by SPSS software version 21 using descriptive statistics (frequency) and analytical statistics (t-test, ANOVA, Pearson's correlation coefficient, linear regression). As a result, Happiness was significantly different by gender, grade, satisfaction in major, collegiate-life satisfaction, personal relationship, health status, perceived economic status. Also happiness showed positive correlation with emotional intelligence, empathy ability, and calling consciousness. Multiple regression analysis revealed that the predictors of happiness were grade, collegiate-life satisfaction, health status, empathy ability, calling consciousness, and emotional intelligence accounting for a total of 49.1% of the variance. Results of this study suggest that it is necessary for nursing students to intervention program aimed at enhance the happiness and it would be effective to focus on strengthening emotional intelligence and empathy ability for them.