• 제목/요약/키워드: Effective

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화기조경탕(化氣調經湯)이 항산화 및 항암효과 (Study on the Anti-oxydative, Anti-tumor effect of Whakijogyungtang)

  • 유미경;김종한;박수연;최정화
    • 한방안이비인후피부과학회지
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    • 제20권1호통권32호
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    • pp.80-98
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    • 2007
  • Objectives : This study was carried out to evaluate anti-oxydative, anti-tumor effect for clinical application of Whakijogyungtang (WJT) Results : 1. DPPH radical scavenging activities of WJT water extracts(Exts) were in proportion as concentration of WJT.(3 ${\mu}g/ml:12.6{\pm}2.3$ %) 2. ABTS+ scavenging activities of WJT water Exts were more effective in high density.(3 ${\mu}g/ml:4.3{\pm}1.6$ %, 10 ${\mu}g/ml$: $11.8{\pm}2.5$ %, 30 ${\mu}g/ml:45.3{\pm}3.2%$ 100 ${\mu}g/ml$: $62.7{\pm}4.8%$) 3. Hydrogen peroxide$(H_2O_2)$ scavenging activities of WJT water Exts were effective.(3 ${\mu}g/ml:4.7{\pm}0.8$ %, 10 ${\mu}g/ml: $8.2{\pm}1.6$ %, 30 ${\mu}g/ml:19.5{\pm}3.2$ % 100 ${\mu}g/ml$: $24.6{\pm}3.8$ %) 4. Anti oxidative effects against linoleic acid were not effective. 5. The generation of $O_2\;^-$ in S-180 cells were according to the concentration of WJT water Exts, specially effective over 100 ${\mu}g/ml$ concentration. 6. The SOD activities in S-180 cells were in proportion as cytotoxicity against S-180 cells of WJT water Exts. 7. The GPx activities in S-180 cells were in proportion as cytotoxicity against S-180 cells of WJT water Exts(more effective on 300 ${\mu}g/ml$ and 1000 ${\mu}g/ml$ concentration), but the catalase activities in S-180 cells were not effective. 8. The results of activites against multi-drug-resistance(MDR) of WJT were as follows. 1) In water Exts from WJT, cytotoxicity against AML-2/D100 with vincristine($IC_{50:}39.78$ ${\mu}g/ml$) was more effective than without vincristine($IC_{50:}$ 183.58 ${\mu}g/ml$), Cross resistance(CR:3.85) was not effective, and anti-MDR activites(RF) was effective.(RF:3.85) 2) In hexane fraction, cytotoxicity against AML-2/D100 with vincristine ($IC_{50:}130.88$ ${\mu}g/ml$) was more effective than without vincristine ($IC_{50:}293.10$ ${\mu}g/ml$) and anti-MDR activites(RF) was effective.(RF:4.61) 3) In chloroform fraction, the cytotoxicity against AML-2/WT and AML-2/D100 was not effective. 4) In ethyl acetate fraction, cytotoxicity against AML-2/D100 with vincristine($IC_{50:}36.43$ ${\mu}g/ml$) was more effective than without vincristine ($IC_{50:}73.07$ ${\mu}g/ml$), Cross resistance(CR:0.53) was not effective, and anti-MDR activites(RF) was effective.(RF:2) 5) In butanol fraction, the cytotoxicity against AML-2/WT and AML-2/D100 was not effective. 6) In $H_2O$ fraction, the cytotoxicity against AML-2/WT and AML-2/D100 was not effective. Conclusion : These result suggest that WJT has antioxidative effects, anti-tumor effects by apoptosis of free radical$(O_2\;^-)$ activity, and anti-MDR activites(especially hexane and ethyl acetate fraction).

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Effective dose from direct and indirect digital panoramic units

  • Lee, Gun-Sun;Kim, Jin-Soo;Seo, Yo-Seob;Kim, Jae-Duk
    • Imaging Science in Dentistry
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    • 제43권2호
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    • pp.77-84
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    • 2013
  • Purpose: This study aimed to provide comparative measurements of the effective dose from direct and indirect digital panoramic units according to phantoms and exposure parameters. Materials and Methods: Dose measurements were carried out using a head phantom representing an average man (175 cm tall, 73.5 kg male) and a limbless whole body phantom representing an average woman (155 cm tall, 50 kg female). Lithium fluoride thermoluminescent dosimeter (TLD) chips were used for the dosimeter. Two direct and 2 indirect digital panoramic units were evaluated in this study. Effective doses were derived using 2007 International Commission on Radiological Protection (ICRP) recommendations. Results: The effective doses of the 4 digital panoramic units ranged between $8.9{\mu}Sv$ and $37.8{\mu}Sv$. By using the head phantom, the effective doses from the direct digital panoramic units ($37.8{\mu}Sv$, $27.6{\mu}Sv$) were higher than those from the indirect units ($8.9{\mu}Sv$, $15.9{\mu}Sv$). The same panoramic unit showed the difference in effective doses according to the gender of the phantom, numbers and locations of TLDs, and kVp. Conclusion: To reasonably assess the radiation risk from various dental radiographic units, the effective doses should be obtained with the same numbers and locations of TLDs, and with standard hospital exposure. After that, it is necessary to survey the effective doses from various dental radiographic units according to the gender with the corresponding phantom.

기존 농업용 저수지에서의 유효저수량의 평가 (Evaluation of the Effective Storage of Existing Agricultural Reservoir)

  • 안태진;조동호;이상호;최계윤;윤용남
    • 한국수자원학회논문집
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    • 제37권5호
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    • pp.353-361
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    • 2004
  • 농업용 저수지의 유효저수량은 물수지 분석을 근거고 한 저수지 모의 운영을 통하여 결정하고 있다. 유역은 유출량에 관하여 고유한 특성을 갖고 있으므로 저수지에서 유효저수량의 결정은 유역으로부터의 유출량을 근거로 하는 것이 타당하다. 본 연구에서는 유역의 유출량을 근거로 한 추계학적 선형계획모형을 정립하고 저수지의 유효저수량을 분석하였다. 선형계획모형을 이용한 저수지 분석에 있어서 선형결정법칙은 Chance-constrained model과 함께 된 석년수와 관계없이 제약조건식을 줄이는데 기여한다. 경기도 안성시에 소재하고 있는 금광저수지를 대상저수지고 선정하여 유효저수량을 분석한 결과, 추계학적 선형계획모형에 의한 유효저수량은 물수지 분석에 의한 것 보다 크게 분석되었다. 본 연구에서 제시된 선형계획모형에 의하여 적정한 유효저수량을 결정하고, 저수지 모의운영을 통하여 결정된 유효저수량의 성능을 평가하는 것이 타당한 것으로 판단된다.

McNamara-분석법에 의한 두부방사선 계측 기준치 (ROENTGENOGRAPHIC CEPHALOMETRIC STANDARD FOR KOREAN ACCORDING TO THE MCNAMARA'S ANALYSIS)

  • 김정민;경희문;권오원;성재현
    • 대한치과교정학회지
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    • 제19권1호
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    • pp.107-122
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    • 1989
  • McNamara씨 분석법에 의한 악안면골의 성장변화 평가 및 한국인 기준치를 얻고자 정상적인 안모 및 교합을 가졌다고 생각되는 $9\~21$세의 388명(9세, 11세, 13세는 2년 간격으로 누년적으로 얻은 것임)을 대상으로 두부방사선규격 사진을 분석하여 다음과 같은 결론을 얻었다. 남녀별 각 계측항목의 연령에 따른 평균치 및 표준편차를 산출하였다. $9\~13$세 사이에서 effective maxillary length, effective mandibular length, lower anterior facial height는 연평균 각각 1.90, 2.89, 0.99mm 증가하였다. 주어진 effective maxillary length에 대한 적절한 effective mandibular length, lower anterior facial height를 추정 할 수 있는 회귀방정식을 얻었다.

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소아 알레르기 비염의 진단과 치료 (Allergic rhinitis in children : diagnosis and treatment)

  • 나영호
    • Clinical and Experimental Pediatrics
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    • 제49권6호
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    • pp.593-601
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    • 2006
  • Allergic rhinitis is a common disease of childhood characterized by nasal, throat, and ocular itching, rhinorrhea, sneezing, nasal congestion. Those affected with allergic rhinitis often suffer from associated inflammatory conditions of the mucosa, such as allergic conjunctivitis, rhinosinusitis, asthma, otitis media with effusion, and other atopic conditions, such as eczema and food allergies. Allergic rhinitis must be diagnosed and treated properly to prevent complications and impaired quality of life. Despite a high prevalence, allergic rhinitis isoften undiagnosed and inadequately treated, especially in the pediatric population. The first step in treatment is environmental control when appropriate. It may be difficult to eliminate all offending allergens effectively to reduce symptoms, so medications are often required. Many different classes of medications are now available, and they have been shown to be effective and safe in a large number of well-designed, clinical trials. Antihistamines are effective in treating immediate symptoms of sneezing, pruritus, watery eyes, and rhinorrhea. Second generation antihistamines are the preferred antihistamines because of their superior side effect profile. Thus, decongestants are commonly used with oral antihistamines. Intranasal corticosteroids are the most effective therapy for allergic rhinitis. Leukotriene modifier may be as effective as antihistamines in treating allergic rhinitis symptoms. Cromolyn sodium is an option for mild disease when used prophylactically, and ipratropium bromide is effective when rhinorrhea is the predominant symptom. When avoidance measures and medications are not effective, specific immunotherapy is an effective alternative. Only immunotherapy results in sustained changes in the immune system. Because of improved understanding of the pathogenesis, new and better therapies may be forthcoming. The effective treatment of allergic rhinitis in children will reduce symptoms and will improve overall health and quality of life, making a happier, healthier child.

도시공원의 접근성 향상 방안 연구 - 경기도 권역을 중심으로 - (Strategies to Improve Parks' Accessibility in City - Focus on Gyeonggi-do Region -)

  • 성현찬;신지영
    • 한국조경학회지
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    • 제33권2호
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    • pp.83-91
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    • 2005
  • The purpose of this study is to analyze the arrangement of parks, in whole city level by using park's effective distance and to find the accessibility obstacles in case of using parks, in boundary of each parks' effective distance, so that to show how to improve communities' usage of city parks. The 8 cities in Gyeonggi-do and analysed the effective distance of parks. To find the accessibility obstacles in the boundary of parks' effective distance, 1) we choose 18 sample parks and extract obstacles - wide road, rail road, river- in interior and verify it by field survey and asking the park user's residents directly. The main findings of this study can be summarized as follows: First, Ansan city and Goyang city are only satisfied with the minimal city parks size standard, so that the rest 6 cities are lack of quantities which residents can use. The result of analyzing effective distance in whole city level, parks are mainly designated in new-town, so that most cities which have old-towns have very poor park systems to use. Because Ansan city is new-planned city, it is very effective arrangement in park systems exceptionally. Second, $96.2\%$ of park users' are living in the area which was easy to gain access not intercepted by wide road, rail road or river. Third, therefore at the stage of planning park, effective distance and resident's accessibility as well as park's supply quantitatively are needed to be considered. In addition, selection of location and elevation of resident's safety and accessibility through making a plan must be reflected. In the low accessibility area, the program to improve park's accessibility and amenity - like making small park or pocket park, linking parks with resident-friendly road etc.- has to be investigated.

국민학교 환경교육의 효율적 지도에 관한 연구 (A Study on the Effective Teaching Method for the Environmental Education in Korean Primary School)

  • 차주혁;김병우
    • 한국환경교육학회지:환경교육
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    • 제7권1호
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    • pp.30-45
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    • 1994
  • This study was conducted to investigate the concern of the primary school teachers and the teaching situation about the environmental education through questionnaire survey on the effective environmental education. The results of questionnaire were analysed and discussed to provide the effective teaching method for the environmental education. The result of this study is as follows. 1. It was found that teachers want to teach environmental lessons as a special subject, and the content of the environmental lessons in textbook was not enough in quantity, the living waste was the most serious ploblem. Owing to the lacking in materials for the lectures on environmental education, most teachers collect the material depending on the mass communication. Also they were more interested in the environmental lessons rather than the other lessons in textbook. But because of the lacking in administrative assistance, they have difficulty in conducting the effective environmental education. 2. The teaching method of the environmental education in most primary schools was a all together-type lecture in classroom. Owing to conducting the environmental education for the knowledge than the action through the extra activity, it was difficult to expect the effect of the environmental education. Also the rate of using the reflection materials which can be improved the studying effect was very low. 3. For the effective environmental education most teachers wanted the spot learnings and the case studies and teacher education and training to get an special knowledge for environmental education. The effective evaluation method for children's environmental education is to present the results by environmental experiences and practices and to formulate a system education is organized for the effective management and activation of environmental education. 4. By practising the seasonal spot learnings, students need to change of learning method and to realize the importance of environment through own self-experiences. 5. In the future, it is desirable that researching of an environmental education is offered the effective practising teaching method which is improving the development of customs and functions, cultivation of the sense of value, ability to solve the problem, to determine the intention as well as the survey on the real situation and the consciousness about environmental education.

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전투 및 비전투 상황에서의 효율적 리더십에 대한 비교 연구 (A Comparative Study on Effective Leadership in Combat and Noncombat Situation)

  • 이재윤
    • 안보군사학연구
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    • 통권5호
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    • pp.203-239
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    • 2007
  • The current problems with the changing nature of the battlefield of the future point up the serious need for more and better research on the nature of effective military leadership. The purpose of this study was to examine effective leadership traits and behaviors of junior officers in combat situation. During times of peace, leader study battles and imagine themselves in all sorts of combat situations while at the same time, they must cope with numerous challenges and fill a variety of roles that they perceive are not battle related. This illustrates one of the fundamental paradoxes of the peacetime environment. Early studies, showing that combat leadership and noncombat leadership needed different talents, produced some clusters of traits which good combat leader were said to possess. Good combat leaders, for example, were described as possessing courage(e.g., bravery, fearlessness, daring, prowess, gallantry, guts, intrepidity, undaunted courage, fighting spirit, aggressive action), personal integrity(e.g., sincerity, flair, calmness, modesty), adaptability(e.g., flexibility, rapidity in action, speedy decision-making, clarity of thought) and so on. Behaviors found to be important in both combat and noncombat situations bore some relation to role requirements common to both situations. Behaviors important in one situation but not the other could be explained in terms of situational differences in role requirements for effective leadership. In order to achieve this purpose, a number of literature reviews were analysed. These results, though obtained in a somewhat rough and ready fashion, were useful not because they pointed to different leaders in war and in peace, but because they showed leaders the different things that were expected of them in different situations. It was also worth knowing how develop combat leadership. While these findings clearly suggest combat and noncombat differences, they do not necessarily confirm the complete study on effective leadership in combat situation. In conclusion, this study would be useful basis for further improvement on effective combat leadership and some further researches were recommended.

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RFIC 설계에 응용 가능한 90nm 공정 기반 인덕터의 Quality factor 및 Effective inductance 분석 (Analysis of Quality factor and Effective inductance of Inductor for RF Integrated Circuits in 90nm CMOS Technology)

  • 장성용;신종관;권혁민;권성규;성승용;황선만;장재형;이가원;이희덕
    • 전자공학회논문지
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    • 제50권5호
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    • pp.128-133
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    • 2013
  • 본 논문에서는 RFIC 설계에 응용 가능한 인덕터의 Quality factor 및 Effective inductance를 비교 분석하기 위해 Octagonal 인덕터를 90nm CMOS 공정을 이용하여 제작하였다. 내부반경을 설계변수로 갖는 인덕터의 경우 내부반경이 증가함에 따라 Quality factor가 감소하고 Effective inductance의 값이 증가하였다. 회전수를 설계변수로 갖는 인덕터의 경우 금속의 회전수가 증가함에 따라 Quality factor의 값이 감소하고 Effective inductance의 값이 증가하는 것을 확인하였다. 따라서 RFIC 회로 설계에 있어서 인덕터의 구조는 Q-factor 및 inductance 각각의 상대적 중요도에 따라 선택 되어져야 된다고 할 수 있다.

유효거리를 이용한 연소기관 노치부의 파손기준 해석 (Analysis of Failure Criterion for Combustion Pipe with Notch using Effective Distance)

  • 김덕회;김재훈;문순일
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2004년도 춘계학술대회
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    • pp.1-6
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    • 2004
  • In this study, the intrinsic static/dynamic fracture toughness of Al 7175=T74 is evaluated from the apparent static/ dynamic toughness of notched specimen, The critical average stress fracture model is suggested to establish the relationship to predict the intrinsic fracture toughness from the apparent fracture toughness of a notched specimen. The critical average stress fracture model is established using the relation between the notch root radius and the effective distance calculated by finite element analysis. Also, effective distance is applied to estimate the failure criterion for the combustion pipe with notch. It is conclude that the true fracture toughness can be estimated from test results of apparent fracture toughness measured by using a notched specimen. Also, the effective In this study, the intrinsic static/dynamic fracture toughness of Al 7175=T74 is evaluated from the apparent static/ dynamic toughness of notched specimen, The critical average stress fracture model is suggested to establish the relationship to predict the intrinsic fracture toughness from the apparent fracture toughness of a notched specimen. The critical average stress fracture model is established using the relation between the notch root radius and the effective distance calculated by finite element analysis. Also, effective distance is applied to estimate the failure criterion for the combustion pipe with notch. It is conclude that the true fracture toughness can be estimated from test results of apparent fracture toughness measured by using a notched specimen. Also, the effective distance can be used to evaluate the failure criterion of structure with notch.

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