• International Journal of Vascular Biomedical Engineering
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• 제1권1호
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• pp.13-23
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• 2003

Backgrounds: The present study in angulated coronary stenosis was to evaluate the influence of velocity and wall shear stress (WSS) on coronary atherosclerosis, the changes of hemodynamic indices following coronary stenting, as well as their effect of evolving in-stent restenosis using human in vivo hemodynamic parameters and computed simulation quantitatively and qualitatively. Methods: Initial and follow-up coronary angiographies in the patients with angulated coronary stenosis were performed (n=80). Optimal coronary stenting in angulated coronary stenosis had two models: < 50 % angle changed(model 1, n=43), > 50% angle changed group (model 2, n=37) according to percent change of vascular angle between pre- and post-intracoronary stenting. Flow-velocity wave obtained from in vivo intracoronary Doppler study data was used for in vitro numerical simulation. Spatial and temporal patterns of velocity vector and recirculation area were drawn throughout the selected segment of coronary models. WSS of pre/post-intracoronary stenting were calculated from three-dimensional computer simulation. Results: Follow-up coronary angiogram demonstrated significant difference in the percent of diameter stenosis between two groups (group 1: $40.3{\pm}30.2$ vs. group 2: $25.5{\pm}22.5%$, p<0.05). Negative WSS area on 3D simulation, which is consistent with re-circulation area of velocity vector, was noted on the inner wall of post-stenotic area before stenting. The negative WSS was disappeared after stenting. High spatial and temporal WSS before stenting fell into within physiologic WSS after stenting. This finding was prominent in Model 2 (p<0.01) Conclusions: The present study suggests that hemodynamic forces exerted by pulsatile coronary circulation termed as WSS might affect on the evolution of atherosclerosis within the angulated vascular curvature. Moreover, geometric change, such as angular difference between pre / post-intracoronary stenting might give proper information of optimal hemodynamic charateristics for vascular repair after stenting.

• 제어로봇시스템학회논문지
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• 제11권5호
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• pp.435-444
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• 2005

This paper presents a lane-departure identification (LDI) algorithm for a traveling vehicle on a structured road. The algorithm makes up for the weak points of the former method based on EDF[1] by introducing a Lane Boundary Pixel Extractor (LBPE), the well known Hough transform, and liner regression. As a filter to extract pixels expected to be on lane boundaries, the LBPE plays an important role in enhancing the robustness of LDI. Utilizing the pixels from the LBPE the Hough transform provides the lane-related parameters composed of orientation and distance, which are used in the LDI. The proposed LDI is based on the fact the lane-related parameters of left and right lane boundaries are symmetrical as for as the optical axis of a camera mounted on a vehicle is coincident with the center of lane; as the axis deviates from the center of lane, the symmetrical property is correspondingly lessened. In addition, the LDI exploits a linear regression of the lane-related parameters of a series of successive images. It plays the key role of determining the trend of a vehicle's traveling direction and minimizing the noise effect. Except for the two lane-related parameters, the proposed algorithm does not use other information such as lane width, a curvature, time to lane crossing, and of feet between the center of a lane and the optical axis of a camera. The system performed successfully under various degrees of illumination and on various road types.

• 한국의류산업학회지
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• 제5권3호
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• pp.267-272
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• 2003

Tactel(Nylon66) union fabrics were woven with the specification of 70d/34f nylon as warp for sport wear jacket. Weft yarn has three types; 100% cotton yarn, nylon core-spun yarn and nylon-polyurethane covering yarn as weft. Fabric structers were plain, twill and satin weave structure with the air jet loom. The mechanical properties of 8 fabrics were measured with KES-F and primary Hand Values and Total Hand Values were calculated. The results of the study were as follows: 1) There was little difference among LTs of N/CM fabric groups. RT of the fabrics with CM100's was bigger than that of fabrics with CM80's, resulting that the fabrics with CM100's have better formability. In terms of weaving structure, twill fabrics have shape deformation. 2) In comparison of RTs with weft yarn type, RT of N-PU covering yarn was the highest, followed by Nylon core-spun yarn and cotton yarn. Thus, the fabric with N-PU covering yarn has better stability of shape deformation. 3) Stretch yarn could express an excellent silhouette formation and twill and satin structures were better structure to make curvature on human form. 4) 2HG/G value of nylon core-spun fabrics was larger than that of N/C fabrics, but the silhouette formation of N/C fabrics was excellent. 5) The RC of N/PU was the highest, followed by N/P, and N/CM. 6) Koski of N/PU fabrics was the highest, Numeri of N/PU and N/Co-I were relatively higher than the others. THVs of N/CM-IV and N/CO-II were lower than the others, resulting that, twill structure was better than plain structure for a sport wear uses.

• Asian Spine Journal
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• 제12권6호
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• pp.1028-1036
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• 2018

Study Design: Single-center, observational, case-control study. Purpose: Comparison and analysis of the metabolic and coagulative profiles in patients with idiopathic scoliosis, patients with congenital scoliosis, and healthy controls. Overview of Literature: Serum melatonin deficiency has been a controversial topic in the etiopathogenesis of scoliosis. Low bone mineral density, low vitamin D3 levels, and high parathyroid hormone levels are common metabolic abnormalities associated with scoliosis that may be responsible for its pathogenesis. In addition to metabolic defects, several studies have shown coagulation defects that either persist from the preoperative period or occur during surgery and usually lead to more than the expected amount of blood loss in patients undergoing deformity correction for scoliosis. Methods: The study population (n=73) was classified into those having congenital scoliosis (n=31), those with idiopathic scoliosis (n=30), and healthy controls (n=12). After detailed clinicoradiological evaluation of all the subjects, 10-mL blood samples were collected, measured, and analyzed for various metabolic and coagulation parameters. Results: The mean serum melatonin levels in patients with idiopathic scoliosis were significantly lower than those in the healthy controls. Although the mean serum melatonin level in the congenital group was also low, the difference was not statistically significant. Serum alkaline phosphatase and parathyroid hormone levels were higher in the scoliosis groups, whereas the vitamin D level was lower. No differences were observed in the coagulation profiles of the different groups. Conclusions: Low serum melatonin levels associated with scoliosis can be a cause or an effect of scoliosis. Moreover, low bone mineral density, high bone turn over, and negative calcium balance appear to play an important role in the progression, if not the onset, of the deformity.

• Steel and Composite Structures
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• 제48권4호
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• pp.385-403
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• 2023

To avoid premature damage to the connection joints of a conventional precast concrete shear wall, a new precast concrete shear wall system (NPSW) based on a plastic damage relocation design concept was proposed. Five specimens, including one monolithic cast-in-place concrete shear wall (MSW) as a reference and four NPSWs with different connection details (TNPSW, INPSW, HNPSW, and TNPSW-N), were designed and tested by lateral low-cyclic loading. To accurately assess the damage relocation effect and quantify the damage and deformation, digital image correlation (DIC) and conventional data acquisition methods were used in the experimental program. The concrete cracking development, crack area ratio, maximum residual crack width, curvature of the wall panel, lateral displacement, and deformed shapes of the specimens were investigated. The results showed that the plastic damage relocation design concept was effective; the initial cracking occurred at the bottom of the precast shear wall panel (middle section) of the proposed NPSWs. The test results indicated that the crack area ratio and the maximum residual crack width of the NPSWs were less than those of the MSW. The NPSWs were deformed continuously; significant distortions did not occur in their connection regions, demonstrating the merits of the proposed NPSWs. The curvatures of the middle sections of the NPSWs were lower than that of the MSW after a drift ratio of 0.5%. Among the NPSWs, HNPSW demonstrated the best performance, as its crack area ratio, concrete damage, and maximum residual crack width were the lowest.

• Archives of Pharmacal Research
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• 제23권5호
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• pp.507-512
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• 2000

This study set out to improve the physical and pharmaceutical characteristics of the present formulation using an appropriate experimental design. The work described here concerns the formulation of the dispersible tablet applying direct compression method containing roxithromycin in the form of coated granules. In this study $2^3$ factorial design was used as screening test model and Central Composite Design (CCC) associated with response surface methodology was used as optimization study model to develop and to optimize the proper formulation of roxithromycin dispersible tablet. The three independent variables investigated were functional excipients like binder (X1), disintegrant (X2) and lubricant (X3). The effects of these variables were investigated on the following responses: hardness (Y1), friability (Y2) and disintegration time (Y3) of tablet. Three replicates at the center levels of the each design were used to independently calculate the experimental error and to detect any curvature in the response surface. This enabled the best formulations to be selected objectively. The effect order of each term to all response variable was X3> X2> Xl> X1＊X2> X2＊X2> X2＊X3> X3＊X3> Xl＊X3> Xl＊Xl and model equations on each response variables were generated. Optimized compositions of formula were accordingly computed using those model equations and confirmed by following demonstration study. As a result, this study has demonstrated the efficiency and effectiveness of using a systematic formulation optimization process to develop the tablet formulation of roxithromycin dispersible tablet with limited experiment.

• 한국정밀공학회지
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• 제30권4호
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• pp.368-374
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• 2013

Maintenance works for current high-rise buildings significantly depend on human labor, unlike other construction processes that are gradually being automated. Herein, this paper proposes robotic building maintenance system using motion control, in specific, reducing a system jerk which is directly subjected to improve the process performance and economic feasibility. The sensor for detecting straight and curvature section of the building facade, moreover rail-joint segment can be detected and be utilized for reducing jerk of the system. Analysis of the proposed system error caused by excessive vibration, e.g. jerk motion is introduced. To enhance the stability and safety of the system, herein, the strategy is proposed for enhancing the performance of the system based on anti-jerk motion control algorithm which comes out increasing the stability and sustainability of the integrated system, as well.

• 설비공학논문집
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• 제17권6호
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• pp.569-580
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• 2005

The present study investigates the convective heat/mass transfer characteristics in wavy ducts of a primary surface heat exchanger. The effects of duct aspect ratio and flow velocity on the heat/mass transfer are investigated. Local heat/mass transfer coefficients on the corrugated duct sidewall are determined using a naphthalene sublimation technique. The aspect ratios of the wavy duct are 7.3, 4.7 and 1.8 with the corrugation angle of $145\Omega$. The Reynolds numbers, based on the duct hydraulic diameter, vary from 300 to 3,000. The results show that at the low Re(Re $\leq$ 1000) the secondary vortices called Taylor-Gortler vortices perpendicular to the main flow direction are generated due to effect of duct curvature. By these secondary vortices, non-uniform heat/mass transfer coefficients distributions appear. As the aspect ratio decreases, the number of cells formed by secondary vortices are reduced and secondary vortices and comer vortices mix due to decreased aspect ratio at Re$\leq$1000. At Re >1000, the effects of corner vortices become stronger. The average Sh for the aspect ratio of 7.3 and 4.7 are almost same. But at the small aspect ratio of 1.8, the average Sh decreases due to decreased aspect ratio. More pumping power (pressure loss) is required for the larger aspect ratio due to the higher flow instability.

• Nuclear Engineering and Technology
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• 제51권3호
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• pp.807-817
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• 2019

Airborne Gamma Ray Spectrometry (AGRS) with its important applications such as gathering radiation information of ground surface, geochemistry measuring of the abundance of Potassium, Thorium and Uranium in outer earth layer, environmental and nuclear site surveillance has a key role in the field of nuclear science and human life. The Broyden-Fletcher-Goldfarb-Shanno (BFGS), with its advanced numerical unconstrained nonlinear optimization in collaboration with Artificial Neural Networks (ANNs) provides a noteworthy opportunity for modern AGRS. In this study a new AGRS system empowered by ANN-BFGS has been proposed and evaluated on available empirical AGRS data. To that effect different architectures of adaptive ANN-BFGS were implemented for a sort of published experimental AGRS outputs. The selected approach among of various training methods, with its low iteration cost and nondiagonal scaling allocation is a new powerful algorithm for AGRS data due to its inherent stochastic properties. Experiments were performed by different architectures and trainings, the selected scheme achieved the smallest number of epochs, the minimum Mean Square Error (MSE) and the maximum performance in compare with different types of optimization strategies and algorithms. The proposed method is capable to be implemented on a cost effective and minimum electronic equipment to present its real-time process, which will let it to be used on board a light Unmanned Aerial Vehicle (UAV). The advanced adaptation properties and models of neural network, the training of stochastic process and its implementation on DSP outstands an affordable, reliable and low cost AGRS design. The main outcome of the study shows this method increases the quality of curvature information of AGRS data while cost of the algorithm is reduced in each iteration so the proposed ANN-BFGS is a trustworthy appropriate model for Gamma-ray data reconstruction and analysis based on advanced novel artificial intelligence systems.

• 센서학회지
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• 제27권6호
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• pp.397-402
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• 2018

Proper seat design is critical to the safety, comfort, and ergonomics of automotive driver's seats. To ensure effective seat design, quantitative methods should be used to evaluate the characteristics of automotive seats. This paper presents a system that is capable of simultaneously monitoring body pressure distribution and surface deformation in a textile material. In this study, a textile-based capacitive sensor was used to detect the body pressure distribution in an automotive seat. In addition, a strain gauge sensor was used to detect the degree of curvature deformation due to high-pressure points. The textile-based capacitive sensor was fabricated from the conductive fabric and a polyurethane insulator with a high signal-to-noise ratio. The strain gauge sensor was attached on the guiding film to maximize the effect of its deformation due to bending. Ten pressure sensors were placed symmetrically in the hip area and six strain gauge sensors were distributed on both sides of the seat cushion. A readout circuit monitored the absolute and relative values from the sensors in realtime, and the results were displayed as a color map. Moreover, we verified the proposed system for quantifying the body pressure and fabric deformation by studying 18 participants who performed three predefined postures. The proposed system showed desirable results and is expected to improve seat safety and comfort when applied to the design of various seat types. Moreover, the proposed system will provide analytical criteria in the design and durability testing of automotive seats.