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Comparison of minimally invasive versus conventional open harvesting technique for iliac bone graft in secondary alveolar bone grafting in cleft palate patients: a systematic review

  • Saha, Aditi;Shah, Sonal;Waknis, Pushkar;Bhujbal, Prathamesh;Aher, Sharvika;Vaswani, Vibha
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.45 no.5
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    • pp.241-253
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    • 2019
  • This study evaluated and compared the donor site morbidity following minimally invasive and conventional open harvesting of iliac bone for secondary alveolar bone grafting in cleft palate patients. A thorough electronic search of PubMed, Google Scholar, EMBASE, and an institutional library and manual search of various journals was done; Inclusion criteria: 1) full-text articles using a minimally invasive or conventional open harvesting technique for iliac bone for secondary alveolar grafting in cleft palate patients and 2) articles published between January 1, 2001 and June 30, 2017 and Exclusion criteria: 1) articles published in languages other than English, 2) case reports, case series, animal studies, in vitro studies, and letters to the editor, and 3) full-text article unavailable even after writing to the authors. Preliminary screening of 274 studies excluded 223 studies for not meeting the eligibility criteria. Of the remaining 51 studies, 19 were removed for being duplicates. Of the remaining 32 studies, 15 were excluded after reading the abstract. Of the 17 studies that were left, 2 were excluded because they were in a language other than English, and 2 were excluded because the study group did not mention cleft palate patients. Thus, 13 studies providing results for a total of 654 patients were included in this qualitative synthesis. Minimally invasive bone graft harvest techniques are better than the conventional open iliac bone harvest method because they offer shorter operative time, decreased requirement for pain medications, less pain on discharge, and a shorter hospital stay.

Research and Publication Ethics: Developing Procedures to Avoid Questionable and Poor Academic Activities

  • KIM, Dongho;YOUN, Myoung-Kil
    • Journal of Research and Publication Ethics
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    • v.2 no.2
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    • pp.21-24
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    • 2021
  • Purpose: This paper aims to evaluate and reinstate preventative guidelines necessary for a sound academic journal (or academic conference) for the articles published by KODISA and its branch journals. As questionable or predatory academic journals and academic conferences are rapidly increasing, preemptively establishing preventative standards have become essential to obviate questionable academic activities. Research design, data and methodology: This is an analytical study that explores and examines research, publication ethics, and misconducts. For this purpose, research ethics related data in overseas and domestic academic journals have been examined and analyzed. Results: The issues identified from this research are as follows: enhancing the expertise of editor-inchief (no concurrent jobs for major and non-major area); clarifying the index; complying with the review policy (The review policy should be publicly announced); complying with anonymous review process; complying with 3 peer-review policy, complying with the publication policy as per field of study; avoiding conference hosting at holiday resorts unless unavoidable; complying with the planned programs and cancelling events if not feasible; following proper review standards and management for all journals, including the journals publishing large number of articles (all materials should be prepared in case explanatory data is required); complying with the marketing policy standards; complying with the impact factor; excluding personal solicitation; and complying with the general policy. Conclusions: Questionable and predatory academic activities by academic organizations and journals will continue, and it is the responsibility of the individual scholars to identify and reject these types of dubious academic activities. This study provides standards to prevent the possibility of questionable academic activities that have been conducted in the past. The analysis and findings will strengthen the continued efforts of KODISA as it strives to be a transparent, ethical, and professional academic association, and the association will continue to foster an academic environment that is well-respected by scholars and practitioners throughout the world.

Reconstruction and Exploratory Analysis of mTORC1 Signaling Pathway and Its Applications to Various Diseases Using Network-Based Approach

  • Buddham, Richa;Chauhan, Sweety;Narad, Priyanka;Mathur, Puniti
    • Journal of Microbiology and Biotechnology
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    • v.32 no.3
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    • pp.365-377
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    • 2022
  • Mammalian target of rapamycin (mTOR) is a serine-threonine kinase member of the cellular phosphatidylinositol 3-kinase (PI3K) pathway, which is involved in multiple biological functions by transcriptional and translational control. mTOR is a downstream mediator in the PI3K/Akt signaling pathway and plays a critical role in cell survival. In cancer, this pathway can be activated by membrane receptors, including the HER (or ErbB) family of growth factor receptors, the insulin-like growth factor receptor, and the estrogen receptor. In the present work, we congregated an electronic network of mTORC1 built on an assembly of data using natural language processing, consisting of 470 edges (activations/interactions and/or inhibitions) and 206 nodes representing genes/proteins, using the Cytoscape 3.6.0 editor and its plugins for analysis. The experimental design included the extraction of gene expression data related to five distinct types of cancers, namely, pancreatic ductal adenocarcinoma, hepatic cirrhosis, cervical cancer, glioblastoma, and anaplastic thyroid cancer from Gene Expression Omnibus (NCBI GEO) followed by pre-processing and normalization of the data using R & Bioconductor. ExprEssence plugin was used for network condensation to identify differentially expressed genes across the gene expression samples. Gene Ontology (GO) analysis was performed to find out the over-represented GO terms in the network. In addition, pathway enrichment and functional module analysis of the protein-protein interaction (PPI) network were also conducted. Our results indicated NOTCH1, NOTCH3, FLCN, SOD1, SOD2, NF1, and TLR4 as upregulated proteins in different cancer types highlighting their role in cancer progression. The MCODE analysis identified gene clusters for each cancer type with MYC, PCNA, PARP1, IDH1, FGF10, PTEN, and CCND1 as hub genes with high connectivity. MYC for cervical cancer, IDH1 for hepatic cirrhosis, MGMT for glioblastoma and CCND1 for anaplastic thyroid cancer were identified as genes with prognostic importance using survival analysis.

A Case Study of Virtual PLC Validation System’s Implementation : In Case of An Automobile Trim Line (가상 PLC 검증 시스템의 구현 사례 : 자동차 의장 라인의 예)

  • Bae, Seong-Hun;Kim, Yearn-Min
    • Journal of the Korea Society for Simulation
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    • v.19 no.2
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    • pp.9-16
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    • 2010
  • This study presents a system for validating the PLC code in the virtual environments of automobile trim line. There have been considerable efforts to develop standard PLC editors for saving human power and PLC test time. However, it was difficult to apply the PLC editor on a real shop floor environment. A virtual equipment was developed to communicate with the PLC module of a shop floor and to make up the connectivity environment by a special protocol. We can validate the code without launching real equipments because the PLC module and the virtual equipment is able to be controlled in real time by the OPC protocol. An experimental model is applied to the final assembly line of an automotive industry and validated by using DELMIA Automation. In conclusion, the system is valuable in the process of PLC codes validation and virtual equipments operation. This system would reduce the development time of the PLC codes and improve the productivity and the integrity of the PLC codes.

A Software Unit Testing Tool based on The XML Test Script for Embedded Systems (XML 테스트 스트립트 기반의 내장형 시스템 소프트웨어 단위 테스트 도구)

  • Kwak, Dong-Gyu;Yoo, Chae-Woo;Cho, Yong-Yun
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.1
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    • pp.17-24
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    • 2009
  • According to increasing requirments in embedded systems, embedded software has been more complicated then before, a software developer is required to test her/his software to make a efficient embedded system software in both time and space. This paper suggests a testing tool with which a software developer can easily test the embedded system software in cross-development environments. The suggested tool is designed based on host/target architecture, to provide an intuitive test environment in which a test case can be executed in a target board. The tool uses an XML-based test script to generate an appropriate test case. It includes a tree-based test script editor with which a developer can easily make a test case. Therefore, with the suggested tool, a develop can put down a burden on an software testing and get more productivity in software development related on embedded system.

Determinants Influencing Housing-Option Decision of Gen Y: The Case of Vietnam

  • Ha Thu LUONG;Dung Manh TRAN;Dan Linh Ngoc NGUYEN;Van Bao NGUYEN;Anh Thuc LE;Hieu Van PHAM
    • Journal of Distribution Science
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    • v.21 no.7
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    • pp.51-63
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    • 2023
  • Housing is not only a basic requirement, but also a method to maintain stability and improve living. In the period of rapid social development which has a significant impact on the aging population, the housing issue is an impediment to Gen Y in Asia. Therefore, solving the housing conundrum is the most effective solution to other social problems. Purpose: This research is conducted to investigate factors influencing housing-option decisions of Gen Y and proposes recommendations to them as well as Governments and the real estate investors. Research design, data, and methodology: The Theory of Planned Behavior was employed with the expanded variables (Financial status, Location, Public services and Government incentives) based on literature review. Results: With 445 valid responses, almost all proposed hypotheses are accepted, which supports the positive interrelationship among variables. In the stage of data processing, we have determined the influence of each factor to the dependent variable "Actual Behavior", thereby helping real estate investors understand their desires, as well as improve the ability to meet customer needs. Conclusion: This is the basis to determine the influence of these factors, thereby providing recommendations to customers and what is more, giving real estate enterprises an insight of customers' demand in order to improve product quality and optimize the benefits of each party.

Ontology-based Information Management for the Systematization of Modernized Hanok Construction Data (온톨로지를 활용한 신한옥 시공기술정보의 체계적 관리 방안)

  • Lee, Heewoo;Moon, Kyeongpil;Jung, Youngsoo;Lee, Yunsub
    • Korean Journal of Construction Engineering and Management
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    • v.24 no.1
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    • pp.51-60
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    • 2023
  • This paper aims to propose a method for the systematic management of construction information using ontology. In particular, it was intended to propose a method to systematically manage the construction method information required by designers and constructors. The information used in this paper is a case of test-bed construction resulting from 10 years of modernized Hanok technology development research. The new construction methods of modernized Hanok were organized using the ontology editor, Protege. To this end, the concept of ontology and the process of constructing ontology have been summarized through a review of existing research first. A conceptual diagram for constructing a domain ontology of the modernized Hanok construction methods was then proposed, and the effectiveness of the proposed domain ontology was verified using the SPARQL Query function of Protege. Finally, the defined classes and construction method metadata were published on the web using ontology web language (OWL).

The Poetic Techniques and Morality of Marianne Moore (마리안 무어의 시적 기교와 도덕성)

  • Choi, Tae-Sook
    • Journal of English Language & Literature
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    • v.56 no.2
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    • pp.219-236
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    • 2010
  • As a poet, a reviewer of books, and an editor of a major literary journal, Marianne Moore participated in aesthetic revolution which invented the American poetry of the twentieth century. Of all the modernists, she was one of the few truly technical originals, and became an endearing mascot of poetry. Innately attentive to detail, Moore wrote a myriad of poems about animal and plant subjects, and set out to develope and secure her own particular paradigm for modernist poetic and the poetry of objective and scientific description. Foregrounding a mind scientifically trained, Moore used her verse to demonstrate a means by which to see the reality beyond the obvious. Ironically enough, however, a central difficulty with understanding Moore's poetry lies with her concern for such scientific or surface description and precision. In order to understand Moore's poetry fully, it is of special necessity to appreciate relativity among the seemingly disparate entities such as science and literature, as Moore herself did. This paper explores the way in which the poetic techniques of Moore substantiate her sense of morality that underlies the creation of her poetry. Rather than merely addressing her artistic genius or craftsmanship as a modernist poet, Moore's methods engage the power of imagination, magic, lifting the human spirit and eschewing anthropocentric perspectives. For Moore, the poet's magic comes by diligence. In so doing, as I would argue here, Moore draws on the nature of language, especially what Bakhtin insisted with his notions of polyphony and carnival. By introducing openness to various perspectives and meanings in her verse, Moore succeeds in maintaining her own sense of creativity while continuing to acknowledge morality. In a similar skein, her use of active verbs in animal poems and the kaleidoscopic descriptions demonstrate how Moore accommodates imagination and reality, and form and content.

Impact of dental imaging on pregnant women and recommendations for fetal radiation safety: A systematic review

  • Thiago Oliveira Gamba;Fernanda Visioli;Deise Renata Bringmann;Pantelis Varvaki Rados;Heraldo Luis Dias da Silveira;Isadora Luana Flores
    • Imaging Science in Dentistry
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    • v.54 no.1
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    • pp.1-11
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    • 2024
  • Purpose: This study was conducted to investigate the safety of dental imaging in pregnant women with respect to fetal health. Materials and Methods: Searches were conducted of the PubMed, Scopus, and Web of Science databases in May 2023. The inclusion criteria encompassed cross-sectional and longitudinal studies that focused on the analysis of diagnostic dental imaging in pregnant women, as well as studies utilizing phantoms to simulate imaging examinations. The exclusion criteria consisted of reviews, letters to the editor, book chapters, and abstracts from scientific conferences and seminars. Results: A total of 3,913 articles were identified. Based on a review of the titles and abstracts, 3,892 articles were excluded, leaving 21 articles remaining for full-text review. Of these, 18 were excluded, and 4 additional articles were included as cross-references. Ultimately, 7 articles underwent quantitative-qualitative analysis. Three retrospective studies were focused on pregnant women who underwent dental imaging procedures. The remaining 4 studies utilized female phantoms to simulate imaging examinations and represent the radiation doses absorbed by the uterus or thyroid. Conclusion: Few dental radiology studies have been conducted to determine the safe radiation threshold for pregnant women. Additionally, the reviewed articles did not provide numbers of dental examinations, by type, corresponding to this dose. Dental imaging examinations of pregnant women should not be restricted if clinically indicated. Ultimately, practitioners must be able to justify the examination and should adhere to the "as low as diagnostically acceptable, being indication-oriented and patient-specific" (ALADAIP) principle of radioprotection.

Acute abdomen following COVID-19 vaccination: a systematic review

  • Nelson Luis Cahuapaza-Gutierrez;Renzo Pajuelo-Vasquez;Cristina Quiroz-Narvaez;Flavia Rioja-Torres;Maria Quispe-Andahua;Fernando M. Runzer-Colmenares
    • Clinical and Experimental Vaccine Research
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    • v.13 no.1
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    • pp.42-53
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    • 2024
  • Purpose: Conduct a systematic review of case reports and case series regarding the development of acute abdomen following coronavirus disease 2019 (COVID-19) vaccination, to describe the possible association and the clinical and demographic characteristics in detail. Materials and Methods: This study included case report studies and case series that focused on the development of acute abdomen following COVID-19 vaccination. Systematic review studies, literature, letters to the editor, brief comments, and so forth were excluded. PubMed, Scopus, EMBASE, and Web of Science databases were searched until June 15, 2023. The Joanna Briggs Institute tool was used to assess the risk of bias and the quality of the study. Descriptive data were presented as frequency, median, mean, and standard deviation. Results: Seventeen clinical case studies were identified, evaluating 17 patients with acute abdomen associated with COVID-19 vaccination, which included acute appendicitis (n=3), acute pancreatitis (n=9), diverticulitis (n=1), cholecystitis (n=2), and colitis (n=2). The COVID-19 vaccine most commonly linked to acute abdomen was Pfizer-BioNTech (messenger RNA), accounting for 64.71% of cases. Acute abdomen predominantly occurred after the first vaccine dose (52.94%). All patients responded objectively to medical (88.34%) and surgical (11.76%) treatment and were discharged within a few weeks. No cases of death were reported. Conclusion: Acute abdomen is a rare complication of great interest in the medical and surgical practice of COVID-19 vaccination. Our study is based on a small sample of patients; therefore, it is recommended to conduct future observational studies to fully elucidate the underlying mechanisms of this association.