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Reconsideration about Nomenclature of Herbs Listed in the Korean Pharmacopoeia (대한민국약전에 수재된 식물성 한약재의 학명에 대한 재고)

  • Doh, Eui-Jeong;Lee, Guem-San
    • The Korea Journal of Herbology
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    • v.28 no.3
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    • pp.61-68
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    • 2013
  • Objectives : A precise and simple system of nomenclature was required to avoid error, ambiguity or confusion. Although medicinal plants must be produced or distributed based on a pharmacopoeia described origin including scientific name, the Korean Pharmacopoeia tenth edition (KP 10) had many names against the nomenclature. Therefore, this study aimed at searching correct scientific names for 241 plants in KP 10. Methods : Authoritative databases - The Plant List, International Plant Name Index, YList, Tropicos, eFloras, World Checklist of Selected Plant Families, The Global Compositae Checklist, The International Legume Database and Information Service, et al. - and previously performed researches, floras were cross-checked. Results : The arrangement of this list was designed for four cases, errors including illegitimate, nomenclatural synonyms, recommended names and decision reserved names. Consideration about the scientific names produced nine correct names for ten misspellings and illegitimate, and thirty-six correct names for forty-one nomenclatural synonyms. These results should be reflected in the next of KP 10. Separately, ten recommended names were also suggested for taxonomic synonyms which had been used indiscriminately due to diverse taxonomic opinions. In addition to those, decision reserved names were suggested for thirteen species which had been corridor of uncertainty. Then again, there was need to study about authorship, because KP 10 did not keep recommendations for author citations. Conclusions : Correction of scientific names for some medicinal plants which violated the International Code of Nomenclature would be useful to improve the accuracy of a Pharmacopoeia as the criterional materials.

Quality Monitoring of Specification Standard of Gardeniae Fructus in the Korean Pharmacopoeia and Studies HPLC Standard Chromatogram (치자(梔子)의 규격 기준 모니터링 및 HPLC 표준크로마토그램 연구)

  • Kim, Kyoung Hee;Kim, Sun Mi;Shin, Seung Hoon;Lee, Young Jong;Baek, Wan Sook
    • The Korea Journal of Herbology
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    • v.32 no.2
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    • pp.97-105
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    • 2017
  • Objectives : Gardeniae Fructus is a ripe fruit of Gardenia jasminoides Ellis, which has been used as traditional medicines for anti-inflammatory, diuretic, antipyretic, and antibacterial activity. The aim of this study was to compare of Gardeniae Fructus in South Korea collected during three years according to the standards in monographs of the Korean Pharmacopoeia Eleventh edition (KP11). Methods : 30 items of Gardeniae Fructus from two cultivation regions were classified into dried(n=15) & steamed (n=15) and tested according to the standards in monographs of the KP11. Gardeniae Fructus was carried out identification(comparison of colors, thin layer chromatography), heavy metals, residual pesticides, total ash, and assay registered at KP11. Add to we tested loss on dry, contents of ethanol-soluble extracts, and HPLC profiling. Results : In TLC chromatogram of identification test, the spot of gardenoside and geniposide were observed at $R_f$ value of about 0.3 and 0.5. Heavy metals and residual pesticides met the requirements of the standards for all samples. The results of total ash of each samples are measured maximum 4.87 %. According to HPLC for assay, the samples contain 4.80~6.10 % of geniposide and 0.45~1.83 % of gardenoside. Conclusion : We have verified the current specification standard of Gardeniae Fructus and standard that is not set. By the results, it is proposed a new draft of loss on drying and confirmed the content of gardenoside revised. HPLC standard chromatogram of Gardeniae Fructus is proposed. We hope that it will help the standardization of Gardeniae Fructus.

Quality evaluation of Angelica gigas Nakai with different drying methods and different root parts (당귀(當歸)의 건조방법 및 뿌리 부위에 따른 품질 평가)

  • Seong, Gi Un;Beak, Mi Eun;Lee, Young Jong;Won, Jae Hee
    • The Korea Journal of Herbology
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    • v.33 no.1
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    • pp.85-91
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    • 2018
  • Objectives : This study was carried out to evaluate the quality of different drying methods and different roots(primary root and lateral root) of Angelica gigas Nakai. Methods : The experimental method was performed according to the Korea Pharmacopoea Eleventh edition (KP11). Loss on drying, ash, acid insoluble ash, ethanol extract, nodakenin and total decursin contents were tested to evaluate the quality of root tissue of Angelica gigas Nakai. In addition, the treatment of different root parts were prepared in two groups of washing dry process and natural dry process. Results : In comparison of dry processing methods, total contents of nodakenin and total decursin in the primary root and lateral root through washing dry process were ranged from 3.55 to 4.09% and from 5.18 to 6.13%, respectively. And also, those of roots from the natural dry process were from 4.36 to 6.22% and from 6.28 to 8.34%, respectively. In the washing dry process and natural dry process methods, 47.9% and 22.3% higher amount of nodakenin and total decursin were measured in lateral root compared to primary root. In common, lateral roots accumulated higher contents of nodakenin and total decursin compared to primary roots, and samples drying processed with natural dry process compared to washing dry process method contained higher amount of compounds. Conclusions : We sincerely hope that this study will be contributed to the standardization and quality control of Angelica Gigas Root.

Daily Dose of Apricot Kernel in Treatise on Cold Damage Diseases (상한론(傷寒論) 탕제에서 행인(杏仁) 1 일 복용량)

  • Kim, In-Rak
    • The Korea Journal of Herbology
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    • v.32 no.6
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    • pp.17-22
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    • 2017
  • Objectives : Daily Dose of Apricot Kernel in Treatise on Cold Damage Diseases is usually written in the number, sometimes in the volume. The seed coat and acute end of Apricot Kernel must be removed, so author want to know its daily dose and proportion of seed coat and acute end. Methods : Assuming dosage by editions of Treatise on Cold Damage Diseases. And comparing it with measured weight of Apricot Kernel distributed in market. Results : The number of prescriptions including Apricot Kernel is ten, and eight of that are made to decoction, two of that are made to pill prescription. And two of decoction are made by reducing and uniting prescriptions. The daily dose of six decoction are 70, 47 or 35 in numbers. The 70 Apricot Kernel except seed coat and acute end are 1/2 Sheong ($33m{\ell}$) in volume, 3 Ryang (19.5 g) in weight. Weight of Apricot Kernel the most common in market is 0.28 ~ 0.38 g. 70 Apricot Kernel are 23.10 g, seed coats of that are 1.15 g, acute ends of that are 2.43 g, 70 Apricot Kernel except seed coat and acute end is 19.5 g. So, seed coat is 5%, acute end is 10% by proportion, which is the same with it assumed based on writings. Conclusions : 70 Apricot Kernel except seed coat and acute end are 1/2 Sheong, 3 Ryang, and it is 33 mL and 19.5 g respectively. It also correspond with current market goods.

Prevention, diagnosis, and treatment of opioid use disorder under the supervision of opioid stewardship programs: it's time to act now

  • Kim, Eun-Ji;Hwang, Eun-Jung;Yoo, Yeong-Min;Kim, Kyung-Hoon
    • The Korean Journal of Pain
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    • v.35 no.4
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    • pp.361-382
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    • 2022
  • The third opium war may have already started, not only due to illicit opioid trafficking from the Golden Crescent and Golden Triangle on the international front but also through indiscriminate opioid prescription and opioid diversion at home. Opioid use disorder (OUD), among unintentional injuries, has become one of the top 4 causes of death in the United States (U.S.). An OUD is defined as a problematic pattern of opioid use resulting in clinically significant impairment or distress, consisting of 2 or more of 11 problems within 1 year, as described by the Diagnostic and Statistical Manual for Mental Disorders, Fifth Edition. Observation of aberrant behaviors of OUD is also helpful for overworked clinicians. For the prevention of OUD, the Opioid Risk Tool and the Current Opioid Misuse Measure are appropriate screening tests before and during opioid administration, respectively. Treatment of OUD consists of 3 opioid-based U.S. Food and Drug Administration-approved medications, including methadone, buprenorphine, and naltrexone, and non-opioid-based symptomatic medications for reducing opioid withdrawal syndromes, such as α2 agonists, β-blockers, antidiarrheals, antiemetics, non-steroidal anti-inflammatory drugs, and benzodiazepines. There are at least 6 recommendable guidelines and essential terms related to OUD. Opioid stewardship programs are now critical to promoting appropriate use of opioid medications, improving patient outcomes, and reducing misuse of opioids, influenced by the successful implementation of antimicrobial stewardship programs. Despite the lack of previous motivation, now is the critical time for trying to reduce the risk of OUD.

Preliminary Validation Study of the Korean Version of the DSM-5 Level 2 Cross-Cutting Symptom Measure: Depression and Irritability for Parents of Children Aged 6-17 Years

  • Shin, Min-Sup;Kim, Bung-Nyun;Jang, Mirae;Shin, Hanbyul;Seo, Gyujin
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.33 no.3
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    • pp.67-72
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    • 2022
  • Objectives: This study investigated the reliability and validity of the Korean version of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) Level 2 Cross-Cutting Symptom Measure-Patient-Reported Outcomes Measurement Information System (PROMIS)-Depression and the Irritability for parents of children aged 6-17 years. Methods: Participants were 190 children diagnosed with depressive disorder (n=14), anxiety disorder (n=21), attention-deficit/hyperactivity disorder (ADHD; n=111), ADHD with anxious depression (n=13), and tic disorder with somatic symptoms (n=31). Patients were 8-15 years of age. The participants' mothers completed the Korean versions of the DSM-5 Level 2 Cross-Cutting Symptom Measure-PROMIS Depression and Irritability (Affective Reactivity Index, ARI), and the Korean Child Behavior Checklist (K-CBCL). Using these data, we calculated the reliability coefficient and examined the concurrent and discriminant validity of the PROMIS Depression and the Irritability (ARI) scales for assessing depression and irritability in children. Results: The reliability coefficient of the PROMIS Depression scale (Cronbach's α) was 0.93. The correlation coefficient with the K-CBCL DSM emotional problem score was 0.71. The PROMIS Depression scale significantly discriminated children with depressive disorders from those with other conditions. The reliability coefficient of the Irritability (ARI) scale was 0.91, suggesting its high reliability. Conclusion: Our results suggest that the Korean version of the DSM-5 Level 2 Cross-Cutting Symptom Measure for Depression and Irritability Scales for parents of children aged 6-17 years is reliable and valid and may be an efficient alternative to the K-CBCL.

A Retrospective Study on the Effect of Complex Korean Medicine Treatment on Social Anxiety Disorder (사회 불안 장애에 대한 한의복합치료의 효과: 후향적 관찰 연구)

  • Jong-Hwan Kim;Jong-Ho Yoo
    • Journal of Oriental Neuropsychiatry
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    • v.34 no.1
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    • pp.33-42
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    • 2023
  • Objectives: This study was conducted to observe the progression of symptoms according to the treatment period of patients with social anxiety disorder who received complex Korean medicine treatment. Methods: The medical records of 25 patients who were diagnosed with social anxiety disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, and received complex Korean medicine treatment (herbal medicine, acupuncture, and Korean psychotherapy) for 12 weeks were analyzed. The State-Trait Anxiety Inventory (STAI), the Beck Depression Inventory-II (BDI-II), the Beck Anxiety Inventory (BAI), the Korean-Social Avoidance and Distress scale (K-SAD), and the Korean-Fear of Negative Evaluation (K-FNE) were measured at the initial hospital visit and during the 4, 8, and 12 weeks of treatment to evaluate the effectiveness of treatment. Missing values were replaced with the average evaluation index value at that time. Results: 1) Statistically significant changes in STAI-X1, STAI-X2, BDI-II, BAI, K-SAD, and K-FNE scores were seen according to the time of treatment. 2) When scores were compared between each treatment time point, STAI-X2 and BDI-II showed statistically significant changes between the initial visit and four weeks of treatment, the initial visit and eight weeks of treatment, and the initial visit and 12 weeks of treatment. STAI-X1 and K-FNE showed statistically significant changes between the initial visit and eight weeks of treatment and the initial visit and 12 weeks of treatment. There was a statistically significant change in BAI scores between the initial visit and the 12th week of treatment. Conclusions: Complex Korean medicine treatment alleviated anxiety, depression, fear, and avoidance of social situation symptoms in patients with social anxiety disorder. The longer the treatment period, the more symptoms tended to be alleviated. However, the evidence should be supplemented with prospective, controlled research.

The effect of animation software interface on design thinking process - Protocol analysis of Alice and KidsPlay - (애니메이션 소프트웨어 인터페이스가 디자인 사고 과정에 미치는 영향 - Alice와 KidsPlay 프로그램 프로토콜 분석을 중심으로 -)

  • Jin, Yan;Lee, Hyun Kyung;Lee, Sang Won
    • Design Convergence Study
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    • v.15 no.1
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    • pp.37-48
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    • 2016
  • Nowadays, CAD has became an essential tool for designers due to its easy edition and manipulation as well as the capability of communication between designers. Differences between design tool interfaces can cause gaps when visualize designer's ideas. This study is about the differences between various levels of metaphor interface language which is based on the theory of the Hutchins that high-level language interface can reduce the steps of process to visualize the idea of the designers than low-level language interface. This research is based on the assumption that high-level language interface will less interrupt the flow of the design thinking and make more various visual outcomes than the low-level language interface. We verified the hypothesis by analyzing differences of design thinking flow between user groups who used two different animation software. Hopefully, the verification of the hypothesis in this study can be able to guide the use pattern of the CAD tools.

A Study on the Definition Methodology of Korean SCI Journals (SCI에 등재된 한국 학술지를 정의하는 방법에 대한 연구)

  • Lee, Choon-Shil;Lee, Nam-Young
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.18 no.2
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    • pp.271-288
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    • 2007
  • The purpose of this study is to investigate how one can find all journals of a country covered in a database such as SCI. We searched SCI and JCR Science Edition 2006 databases for Korean journals using four definition criteria-Country of a journal publication, Editorship, Unique words appeared in a journal title designating a country, a number of papers from a country in a journal. We also checked related literatures and websites to find information on SCI Korean journals. The study shows that 40 Korean journals were covered in SCI in 2006. SCI identified 38 of them as journals from South Korea, and JCR 2006 included 36. 11 journals had unique words indicating that they are Korean journals. 9 journals were Korean journals among the top 20 SCT journals by the number of papers with Korean addresses, and 36 journals were included among the top 500 SCI journals.

Mapping Publication Pattern in African Journal of Library, Archives and Information Science, 2009-2018: An Informetric Study

  • Amusan, Blessing Babawale;Adeyoyin, Samuel Olu
    • International Journal of Knowledge Content Development & Technology
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    • v.12 no.1
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    • pp.17-34
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    • 2022
  • This informetrics study was conducted to find out the distribution of articles and authors that published in African Journal of Library, Archives and Information Studies [AJLAIS]) from 2009 to 2018; considering the year-wise growth of research articles; authorship pattern and collaboration ratio; subject and geographical distributions of authors; and authors' productivity level. A descriptive informetrics research design was adopted. Quota sampling technique was used to select all the articles published within the ten-year period. Data collected through a self-designed checklist was analyzed using frequency count and percentage. The findings revealed that 141 articles, contributed by 266 authors were published by AJLAIS during the period. An annual average growth of 1.20% was recorded. Overall year-wise authorship pattern revealed that majority of articles (62.41%) published in AJLAIS were multiple authored. Also, articles on Informetrics and ICT dominated the journal. Some subject areas not covered were identified such as: indexing and serial collections management. Average collaborative index across the 10-year period for the journal was 0.62. South Africa and Nigeria were the two major prolific contributors to AJLAIS, just as evidence-based research papers of survey type (65.25%) were the most common to the journal. There should be increased numbers of articles in each edition over the coming years, and awareness should be created by the publishers to familiarize the researchers with the publishing requirements of the journal. Also, LIS researchers should concentrate more on areas usually left untouched by previous studies. The study is original as no other similar study was found on publication pattern of articles in AJLAIS covering a ten year period of 2009-2018. The findings of the study will also serve as a feedback mechanism for the Publisher of the Journal and LIS researchers on how to improve the journal and LIS research in general.