While the medical supplies have positive functions such as extending lifespan, recovering health, and preventing diseases, they also cause unexpected tragic consequences due to their side effects, and the magnitude of such damage inevitably increases due to the mechanism of mass production, mass distribution, and mass consumption of those medical supplies. Therefore, needless to say, the optimal way to prevent or reduce such damage is rather through medical supply manufacturers' producing non-defective products, or through the government's controlling production and sales of medical supplies with more aggressive exercise of regulatory authority on medical supply manufacturers, than through a remedy by a legal relief after using medical supplies. In this case, although the victim died due to the defect of the cold medicine, 'CONTAC 600', the drug company's responsibility to cover damages was not recognized because a defect could not be found in the then-manufacturing process. Thus, while pharmaceutical companies are gaining economic profits by producing and selling a medical supplies, if they do not take any remedy measures for the victims of their products' side effects, the victims have to use medical supplies under their own responsibility of taking a risk, and they have to accept the full damage of the potential consequence. Therefore, to remove such absurdity and contradiction, and to practically remedy the victim of medical supplies' side effects, the pharmaceutical side effects remedy project pending in the the Drugs, Cosmetics and Medical Instruments Lawneeds to be actively implemented.
Journal of Korean Society of Occupational and Environmental Hygiene
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v.28
no.4
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pp.365-373
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2018
Objective: This study aims to analyze the relationship between employment status and the prevalence of chronic obstructive pulmonary disease (COPD) for manufacturing and construction workers. Methods: Subjects, who had or have worked as temporary workers in manufacturing or construction worksites for the longest career years, were extracted from the KNHANES(2007-2009) database. Characteristics of demographical, socio-economic, and smoking history were treated as independent variables. Considering that smoking experience and age are significantly influential in the prevalence of COPD, logistic regressions were analyzed after stratifying subjects according to their smoking experience and age. A two-stage stratified systematic sampling method was applied for the logistic regression analysis. Results: Age, gender, and household income level were associated with the prevalence of COPD in both smoking and non-smoking groups. However, employment status was only significant among smoking group. Smoking experience and age were significantly related to the prevalence of COPD among all age groups. In addition, employment status and household income level were also associated with the prevalence of COPD in young aged group. But gender was the only significant factor among the elder group. Conclusions: This study confirmed that employment status was a major social factor which may be related to the prevalence of COPD. Proper supports such as providing safety measures should be provided to temporary workers to manage their respiratory health.
Purpose: This study aims to develop a cost model for NRP (Nursing Residency Program) operation and ultimately provide evidence for financial factors for NRP operation in the future by simulating a cost model. Methodology: This study developed a model for the NRP education cost calculation model based on the review of Hansen's model, which has systematically reported on the development and operation of NRP, and discussions with nursing education experts at a university-affiliated hospital. With the simulation, it was intended to predict nurses' supply and demand in the long term and to calculate changes in long-term education costs. Findings: Firstly, turnover model, term model, cost model necessary for calculating a model for the NRP education cost calculation model was set up. Secondly, the simulation showed the following results; 1) the proportion of newly graduated nurses less than 5 years of working decreases gradually over time, which will make the composition of nurses more balanced. 2) In the first year of the partial introduction of NRP, the cost of training new nurses was about 2.1 times higher than before. After the introduction, the training cost in the 13th year began to be lesser than before the introduction, and in the 25th year, it decreased by 28.1% compared to before the introduction. Practical Implications: Firstly, NRP would be an effective way to solve the higher turnover and frequent departure of new nurses and the imbalance of nurses' composition. Secondly, although the costs of NRP are incurred in the early stages, in the end, NRP training costs are reduced compared to before the introduction of NRP. It is necessary to systematically understand the contribution effect of NRP by analyzing the economic value of NRP considering financial and non-monetary returns in the future and providing a basis for decision-making related to NRP implementation.
Purpose - Although the government and civic groups do not always confront each other over the Me Too movement, the two stakeholders are often conflicted. For example, the two interested parties may have different positions in the gender conflict and be often hostile due to debates over how to institutionalize and distinguish actual harm from innocence. In this situation, the strategies of the two stakeholders for their own ends are inevitably interdependent. This paper is a study on the strategic reciprocity of interested parties in relation to the Me Too Movement, which has recently raised a new discourses in our society. Design/methodology/approach - We derive equilibrium of the reciprocity between civic groups(collectively referred to as the Me Too Movement Headquarters) leading the Me Too Movement and government that must preemptively respond to new social issues, and analyze how changes in some external conditions affect the reactions of the two stakeholders. For this purpose we rely on economic methodology. Findings - In the reciprocity between the two forces, we derive an equilibrium composed of the pair of the government's optimal response level and the civic group's optimal strategy, and further derive the comparative static results according to changes in external conditions. Analysis results are mixed with intuitive results and non-intuitive ones. However, even if the result is not intuitive, rational reasoning is possible as long as it is derived through a rigorous model, and it has several implications. Research implications or Originality - Although this study is a positive approach, it is meaningful as a starting point to explore practical discussion directions and alternatives by adding another new perspective and approach to research in other social science fields with many normative studies.
We report a case of successful treatment of congenital syphilis in an extremely preterm baby. A 1,395 g female infant was born by emergency Caesarean section due to preterm labor and breech presentation at gestational age at 29 weeks and 3 days with an Apgar score of 2 and 4 at 1 minute and 5 minutes, respectively. The mother of the newborn, an illegal immigrant who did not receive any antenatal care, was diagnosed as active syphilis infection by reactive rapid plasma regain (RPR) (titer 1:128) just before the delivery. Upon birth, the newborn presented with various clinical manifestations, including severe respiratory distress syndrome, persistent pulmonary hypertension of the newborn, disseminated intravascular coagulopathy, desquamation and scaling of the whole body, and osteolytic changes of long bone ends. Results of laboratory tests showed signs of early congenital syphilis, including positive syphilis reagin test (12.7 R.U.), reactive with RPR titer of 1:64, and positive for immunoglobulin (Ig) M and IgG fluorescent treponemal antibody absorption test. However, after completion of penicillin G treatment for two weeks, laboratory results dramatically improved, showing a negative syphilis reagin test (0.5 R.U.) and non-reactive in RPR. In conclusion, the incidence of congenital syphilis is prone to be resurgent in South Korea, neonatologists should be fully aware of the clinical features of congenital syphilis because early diagnosis and prompt treatment are essential in order to reduce the social and economic burden due to congenital syphilis.
Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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2022.05a
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pp.133-136
/
2022
As the number of stress-related diseases increases due to the prolonged Corona 19, Corona Blue is attracting attention. This social background causes negative emotions due to frustration at work, changes in existing life rhythms, and blockade of economic sources, and makes us understand our era as an era in need of healing. Therefore, the purpose of this study is to propose a 3D-based adventure filming game that adventures a fantastic space and stores memories and experiences through photos. For this, important elements of healing were explored through literature study, and based on this, a game using 3ds Max and Unity was implemented. As a result of the study, the game was implemented with a filming function that contains visual elements for cute and warm healing, an emotionally approaching story, and the meaning of space. This study provides a game that can provide non-face-to-face healing to users and presents effective and important healing factors to service providers.
As the global market becomes more competitive, manufacturing industries face relentless pressure caused by a growing tendency of greater varieties of products, shorter manufacturing cycles and more sophisticated customer requirements. Efficient and effective supplier selection and order allocation decisions are, therefore, important decisions for a manufacturer to ensure stable material flows in a highly competitive supply chain, in particular, when customers are willing to accept products with less desirable product attributes (e.g., color, delivery date) for economic reasons. This paper attempts to solve optimally the challenging problem of supplier selection and order allocation, taking into consideration the customer flexibility for a manufacturer producing multi-products to satisfy the customers' demands in a multi period planning horizon. A new mixed integer programming model is developed to describe the behavior of the supply chain. The objective is to maximize the manufacturer's total profit subject to various operating constraints of the supply chain. Due to the complexity and non-deterministic polynomial-time (NP)-hard nature of the problem, an improved genetic approach is proposed to solve the problem optimally. This approach differs from a canonical genetic algorithm in three aspects: a new selection method to reduce the chance of premature convergence and two problem-specific repair heuristics to guarantee feasibility of the solutions. The results of applying the proposed approach to solve a set of randomly generated test problems clearly demonstrate its excellent performance. When compared with applying the canonical genetic algorithm to locate optimal solutions, the average improvement in the solution quality amounts to as high as ten percent.
Journal of the Korean Society of Manufacturing Technology Engineers
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v.22
no.3
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pp.343-348
/
2013
In line with the advances in factory automation, various pieces of equipment are now operated in batch processes controlled by computers. However, many kinds of faults can occur in complicated and large systems, which can result in low productivity and economic loss. The reliability and safety of systems have been studied because of the difficulty of determining the severity and location of faults. Therefore, it is necessary to detect and diagnose such faults in order to guarantee the reliability and safety of the equipment. In this paper, a diagnosis method for the ball bearings of a hydraulic pump is applied using a vibration signal for the maintenance of injection molding equipment. The bearings' defects are selected as a main failure mode through a failure mode and effect analysis (FMEA). Usually, there are nonlinear and impulse components of vibration in a ball bearing with faults. For the effective fault diagnosis of a ball bearing, nonlinear diagnostic methods and time-frequency analysis are applied, in addition to the methods currently used, such as power spectrum, time series analysis, and statistical methods. As a result of this study, a failure diagnosis system is provided that is useful even for non-experts. This is a condition-based method that makes it possible to resolve problems in a timely and economical way, in contrast to the prior method, which required regular but wasteful maintenance based on the experience of expensive external experts.
Journal of Korea Technical Association of The Pulp and Paper Industry
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v.45
no.1
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pp.75-82
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2013
The traditional Hanji-making was confronted with lots of industrial disadvantages and economic problems, due to the original hand-made process. Recently, the studies on the automation of overall Hanji manufacturing process is carried out by applying the commercial chemical pulping method in order to expand industrial application or efficiency of non-wood fibrous materials. However, the application of commercial pulping methods to the bast tissues of paper mulberry leads to the chemical and mechanical deterioration of cellulosic fibers. In this study, the optimal cooking method using the bast parts of paper mulberry produced by an auto-scraping device was applied to minimize the damage of fiber strength for the paper yarn manufacture. The pre-steaming treatment and alkaline pulping systems were evaluated in removal efficiency of lignin and pectin materials within the bast tissue of paper mulberry. With the application of pre-steaming treatment and 2 stage pulping system using potassium carbonate and then sodium hydroxide, kappa values were decreased two times more in lignin removal than the single stage of pulping method. It was also identified from SEM images and ATR-FTIR spectra that the pectin components within cellular structure of bast tissue were easily removed and the debarked bast parts by a auto-scraping device were easily defiberized by 2-stage pulping sequence using potassium carbonate/sodium hydroxide pulping system.
Kim, Yong Sang;Park, Hyeok Joo;Lee, Dong Hee;Kim, Hyun Kyu
Korean Journal of Medicinal Crop Science
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v.26
no.1
/
pp.26-31
/
2018
Background: Angelica gigas, A. sinensis, and A. acutiloba are commercially important in the herbal medicine market, and among them, A. gigas has the highest economic value and price. However, their similar morphological traits are often used for fraud. Despite their importance in herbal medicine, recognition of the differences between Angelica species is currently inadequate. Methods and Results: A multiplex polymerase chain reaction (PCR) method was developed for direct detection and identification of A. gigas, A. sinensis, and A. acutiloba. The gene for the distinction of species was targeted at ITS in the nucleus and trnC-petN gene in chloroplasts. The optimized multiplex PCR in the present study utilized each Angelica species-specific primer pairs. Each primer pair yielded products of 229 base pairs (bp) for A. gigas, 53 bp for A. sinensis, 170 bp for A. acutiloba. Additionally non-specific PCR products were not detected in similar species by species-specific primers. Conclusions: In the present study, a multiplex-PCR assay, successfully assessed the authenticity of Angelica species (A. gigas, A. sinensis, and A. acutiloba). and whole genome amplification (WGA) was performed after DNA extraction to identify, the species in the product. The detection method of raw materials developed in the present study could be applied to herbal medicine and health functional food management.
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