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Antiviral Effects of Natural Products on the Inhibition of Hepatitis B Virus DNA Replication in 2.2.15 Cell Culture System

  • Nam, Kung-Woo;Chang, Il-Moo;Choi, Jae-Sue;Hwang, Ki-Jun;Mar, Woong-Chon
    • Natural Product Sciences
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    • v.2 no.2
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    • pp.130-136
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    • 1996
  • Evaluation of plant extracts that might inhibit hepatitis B virus (HBV) replication was performed to find potent anti-HBV agents. Eighty-five species of plants from forty-three families were tested for their anti-HBV activities using HBV-producing HepG2-derived 2.2.15 cells. The anti-HBV activity of plant extracts was measured by slot blot hybridization technique and cytotoxicity was determined by crystal violet staining procedure. All plants were extracted with methanol and the extracts were partitioned into n-hexane, ethyl acetate and aqueous layer. The ethyl acetate fractions of Rhus verniciflua $(stem:\;EC_{50},\;8.2{\mu}g/ml;\;CC_{50},\;9.4{\mu}g/ml)$, Gastrodia elata $(root:\;EC_{50},\;17.7{\mu}g/ml;\;CC_{50},\;>20{\mu}g/ml)$, Raphanus sativus $(seeds:\;EC_{50},\;17.3{\mu}g/ml;\;CC_{50},\;>20{\mu}g/ml)$, and Angelica gigas $(root:\;EC_{50},\;8.3{\mu}g/ml;\;CC_{50},\;15.6{\mu}g/ml)$ revealed the anti-HBV activity in 2.2.15 cell culture system and these fractions are under the process of further sequential fractionation by column chromatography to find the active principles against HBV.

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An Evaluation of Axial Compressive Strength in Steel Stud (스틸스터드의 압축내력 평가)

  • Shin, TaeSong
    • Journal of Korean Society of Steel Construction
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    • v.10 no.4 s.37
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    • pp.677-689
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    • 1998
  • In relation to concentrically loaded compression, this research is to describe, analyze, and evaluate the design strength in steel stud. The similarity and difference among load and resistance factor design specification for cold-formed steel structural members (AISI), cold-formed thin gauge members and sheeting (EC3 part 1.3), and German draft (DASt-Richtlinie 016) are introduced, discussed, and systematically evaluated. Especially, the effective width and global instability problems (flexural buckling and torsional flexural buckling) are here implied in this research. The design axial strength by dual standards (AISI and EC3) is calculated and compared using the example.

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A Study on Characteristics of Groundwater Qualities at the Ulsan Metropolitan City (울산도시지역의 지하수 수질특성에 관한 연구)

  • 김병우;정상용;조병욱;윤욱;성익환;심병완
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2004.04a
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    • pp.482-486
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    • 2004
  • 울산지역 수질특성에 관하여 연구하기 위해 228개 지점에서 수질성분 25개 항목을 분석하였다. 그 성분중 지하수 음용수 9개 수질성분(pH, EC, TDS, Cl, Mn, NO$_3$, SO$_4$, F, Fe)에 관해 수질분포특성 및 오염도를 나타내기 위해 모수적 통계기법인 정규크리깅과 비모수적 통계기법인 지시크리깅 기법을 적용하였다. OK와 IK의 성분별 베리오그램 분석한 결과 OK의 경우 모든 수질성분은 구상형모델(Spherical model)로 선정되었으며, IK의 경우 pH, TDS, SO$_4$, Cl, Mn, F, Fe 성분은 구상형모델로, EC는 지수형모델로, NO$_3$는 선형모델로 선정되었다. 그 결과 정규크리깅의 경우 연구지역의 수질특성을 정량적 분포특성이 잘 나타났다. 특히 태화강, 인접한 남구일원과 중구일원, 북구의 북서 일원 그리고 동구의 방어동일원에서 수질성분 9개 성분들이 다소 높게 나타났다. 특히 EC, TDS 그리고 Cl$^{-}$ NO$_3$ 성분이 높게 나타났다. 그리고 지시크리깅의 경우 정규크리깅과 비교하여 이상치가 크게 영향을 미칠 수 있는 통계학적인 오류를 보완하여 분석한 결과 울산지역 9개 성분 오염도는 EC>TDS>NO$_3$>pH>Fe>Mn>Cl>SO$_4$>F 순으로 오염특성이 나타났다.

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The electrochromic properties of tungsten oxide thin films coated by a sol-gel spin coating under different reactive temperature (솔-젤 스핀 코팅에 의해 증착된 텅스텐 산화물 박막의 반응 온도에 따른 전기변색특성 연구)

  • 심희상;나윤채;조인화;성영은
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2003.11a
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    • pp.128-128
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    • 2003
  • Electrochromism (EC) is defined as a phenomenon in which a change in color takes place in the presence of an applied voltage. Because of their low power consumption, high coloration efficiency, EC devices have a variety of potential applications in smart windows, mirror, and optical switching devices. An EC devices generally consist of a transparent conducting layer, electrochromic cathodic and anodic coloring materials and an ion conducting electrolyte. EC has been widely studied in transition metal oxides(e.g., WO$_3$, NiO, V$_2$O$\sub$5/) Among these materials, WO$_3$ is a most interesting material for cathodic coloration materials due to its lush coloration efficiency (CE), large dynamic range, cyclic reversibility, and low cost material. WO$_3$ films have been prepared by a variety of methods including vacuum evaporation, chemical vapor deposition, electrodeposition process, sol-gel synthesis, sputtering, and laser ablation. Sol-gel process is widely used for oxide film at low temperature in atmosphere and requires lower capital investment to deposit large area coating compared to vacuum deposition process.

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A Study on Vitalization of the Activities of Online Shopping Mall in Quality Management System (품질경영체제에서 온라인쇼핑몰의 활성화에 관한 연구)

  • 김형욱;정인진
    • Journal of Korean Society for Quality Management
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    • v.29 no.2
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    • pp.54-75
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    • 2001
  • The tremendous growth of the Internet, particularly World Wide Web, has resulted in significant changes in commerce environments. Internet has brought significant changes in the economics of marketing channels and has led to a redefinition of industry value chain. Electronic Commerce(EC) has become so important that countries and firms unprepared for this new trend would lose competitive advantages in the coming century of Digital Economy. Despite its importance, current EC markets in Korea are immature and there still exist several barriers to EC development thus excluding business to consumer EC markets. As interest in quality management and its effect on competitive performance has grown, there has been a corresponding proliferation of research. However, the majority of the research on quality management has not evolved in a comprehensive and rigorous fashion, particularly with regard to reliability and validity issues. The purpose of this paper investigates on Vitalization of the Activities of on-line shopping mall under of TQM system in Korea. That would make it possible to remove elements of insecurity and doubt currently felt by many users of on-line shopping mall(internet detail or cyber mall) business. In addition, we tried to find out what factors discourage consumers from using electronic purchasing methods, as well as how perceived quality factors and customer satisfaction when consumers are exposed to the purchase process on the on-line shopping mall business.

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Characteristics of Chemical Species in $PM_{205}$ during the Winter in Kangwha (강화도 지역에서 겨울철 $PM_{205}$의 화학적 성분 특성)

  • 여현구
    • Journal of Korean Society for Atmospheric Environment
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    • v.16 no.4
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    • pp.309-316
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    • 2000
  • Chemical compositions of air pollutants with fine particles (<2.5 ${\mu}{\textrm}{m}$, PB2.5) were evaluated at background site. Kangwha. in Korea during the winter season. The data set was obtained for seventeed days with 24-hour sampling from December 11 to 16, 1996 and from January 9 to 1997. The chemical species have been measured {{{{ {SO }`_{4 } ^{2- } }}}}, {{{{ { NO}`_{3 } ^{- } }}}}, {{{{ { NH}`_{4 } ^{+ } }}}}. OC and EC in the particulate phase, NH3 HNO3, HCl and SO2 in the gas phase using the three stage filter pack method. Mean concentration ($\mu\textrm{g}$/m3) of this study were : 35.42 for PM2.5 8.78 for organic carbon (OC) 7.25 for nss {{{{ {SO }`_{4 } ^{2- } }}}}, 4.94 for {{{{ { NO}`_{3 } ^{- } }}}}, 3.58 for {{{{ { NH}`_{4 } ^{+ } }}}} and 1.48 for elemental carbon (EC) respectively. Contributive rates of major particulate components in PM2.5 were OC (25%) nss- {{{{ {SO }`_{4 } ^{2- } }}}}(20%) ,{{{{ { NO}`_{3 } ^{- } }}}}(14%) {{{{ { NH}`_{4 } ^{+ } }}}}(10%) and EC (4%) respectively and these components could be accounted for 73% of PM2.5 mass. Reactive forms of {{{{ { NH}`_{4 } ^{+ } }}}} were considered as NH4HO3 and NH4{{{{ {SO }`_{4 } ^{2- } }}}} during the sampling periods. {{{{ { NO}`_{3 } ^{- } }}}}/({{{{ { NO}`_{3 } ^{- } }}}} + HNO3) and {{{{ {SO }`_{4 } ^{2- } }}}}/({{{{ {SO }`_{4 } ^{2- } }}}} + SO2) were calculated 0.8 and 0.9 respectively. Most of these compounds might be formed in partiiculate phase in the air. Correlation coefficient between OC and EC was 0.866 which might have the same sources during the sampling periods,.

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Development of an Automatic Nutrient-Solution Supply System Using Fuzzy Control (퍼지제어를 이용한 양액 자동공급 시스템 개발)

  • 황호준;류관희;조성인;이규철;김기영
    • Journal of Biosystems Engineering
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    • v.23 no.4
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    • pp.365-372
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    • 1998
  • This study was carried out to develop a nutrient-solution mixing-and-supplying system, which used a low-cost metering device instead of expensive metering pumps and a fuzzy logic controller. A low cost and precise overflow-type metering device was developed and evaluated by testing the flow discharge for the automatic nutrient-solution mixing-and-supplying system for snail-scale hydroponic sewers. The fuzzy logic controllers, which could predict and meet the desired values of EC and supply rate of nutrient solution were developed and verified by simulation and experiment. this fuzzy logic controller, whose algorithm consists of four crisp inputs, two crisp outputs and nine rules, was developed to predict the desired value of EC and supply rate of nutrient solution and two crisp inputs, one crisp output and nine rules used to control EC to the desired values. The nutrient-solution mixing-and-supplying system showed satisfactory EC control performance with the maximum overshooting of 0.035 mS/cm and the maximum settling time of 15 minutes in case of increasing 0.7 mS/cm. also, the accuracy of the overflow-type metering device in terms of the full-scale error was 2.29% when using solenoid valve only and 0.2% when using solenoid valve and flow control valve together.

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Response of non-structural components mounted on irregular RC buildings: comparison between FE and EC8 predictions

  • Aldeka, Ayad B.;Chan, Andrew H.C.;Dirar, Samir
    • Earthquakes and Structures
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    • v.6 no.4
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    • pp.351-373
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    • 2014
  • This paper investigates the seismic response of lightweight acceleration-sensitive non-structural components (NSCs) mounted on irregular reinforced concrete (RC) primary structures (P-structures) using non-linear dynamic finite element (FE) analysis. The aim of this paper is to study the influence of NSC to P-structure vibration period ratio, peak ground acceleration, NSC to P-structure height ratio, and P-structure torsional behaviour on the seismic response of the NSCs. Representative constitutive models were used to simulate the behaviour of the RC P-structures. The NSCs were modelled as vertical cantilevers fixed at their bases with masses on the free ends and varying lengths so as to match the frequencies of the P-structures. Full dynamic interaction is considered between the NSCs and P-structures. A set of 21 natural and artificial earthquake records were used to evaluate the seismic response of the NSCs. The numerical results indicate that the behaviour of the NSCs is significantly influenced by the investigated parameters. Comparison between the FE results and Eurocode (EC8) predictions suggests that EC8 underestimates the response of NSCs mounted on the flexible sides of irregular RC P-structures when the fundamental periods and heights of the NSCs match those of the P-structures. The perceived cause of this discrepancy is that EC8 does not take into account the amplification in the dynamic response of NSCs induced by the torsional behaviour of RC P-structures.

A Study on Escherichia Coli Disinfection by the Electrochemical Method for Small Sewerage System (소규모 오수처리를 위한 전기화학적 방법에 의한 대장균 소독에 관한 연구)

  • Park, Young-Seek;Jeong, No-Sung;Kim, Dong-Seog
    • Journal of Environmental Science International
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    • v.16 no.4
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    • pp.441-447
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    • 2007
  • This study was carried out to investigate the effect of electrochemical (EC) disinfection of artificial wastewater contaminated by Escherichia coli culture. Circulated batch type electrochemical disinfection system using three plates electrodes was used. Also, the several factors (pH, ORP, DO, temperature, current, conductivity) were measured in order to investigate the fundamental design factor in the EC disinfection system. It was demonstrated that the EC process was highly effective for wastewater disinfection. At the constant voltage, the disinfection efficiency was increased according to time. The disinfection efficiency and current increased as the increase of voltage. The variation of conductivity was a little related to the variation of CFU (colony forming units). The differences in disinfection efficiency according to the ice pack and the variation of electrodes were not occurred. The EC disinfection efficiency and current increased according to the increase of circulating flow rate.

Aerospace Industry promotion under WTO regime (WTO 체제 내의 항공우주산업진흥)

  • Lee, Joon
    • Current Industrial and Technological Trends in Aerospace
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    • v.6 no.2
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    • pp.11-21
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    • 2008
  • This paper focuses on finding the way of aerospace industry promotion in Korea compatible with fair trade system under international rules by considering and analysing the WTO subsidy rules and WTO dispute settlement cases. As for subsidy rules in WTO, the paper deals with two matters such as financial contribution and benefit and further studies provisions on the prohibited subsidies and actionable subsidies. And as for the dispute settlement matters, it reviews the Brazil-Canada case and the US-EC case on civil aircraft export subsidies. While aerospace industry in Korea is not yet internationally competitive still requiring government's continuous supports, it must not be in conflict with subsidy rules under WTO mechanism. This paper makes several suggestions to meet these conditions.

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