• Journal of Physiology & Pathology in Korean Medicine
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• v.38 no.5
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• pp.187-195
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• 2024

Bones and teeth impact quality of life and serve as important indicators of overall health, and diseases such as osteoporosis and periodontitis are emerging as increasingly significant health issues in aging societies. In traditional Korean medicine(TKM), bones and teeth are classified under the kidneys, explaining their interrelationship, and biomedical studies have been published on this connection. This study aims to compare the perspectives of TKM and biomedicine on the relationship between the kidneys, bones, and teeth, focusing on similarities between the two disciplines. The fact that the kidneys produce active vitamin D, which contributes to skeletal formation, and that sex hormones, which influence the lifespan of osteoclasts and osteoblasts, resemble the role of the kidneys(腎) in TKM, which are associated with growth and reproduction, aligns with the TKM concept that "the kidneys govern the bones" (腎主骨). Furthermore, the histological similarity between bones and teeth, as well as the metabolic parallels involving osteoclast metabolism, retinoic acid metabolism, and vitamin D, support the idea that "teeth are the surplus of bones" (齒者骨之餘). In addition to the kidneys acting on the shared pathways of bones and teeth, the pathological link between kidney deficiency(腎虛) and dental diseases-caused by aging, overwork, or congenital deficiencies-explains the concept that "the kidneys govern the teeth"(腎主齒). This study contributes to an integrated understanding of both disciplines by comparing the TKM concept with biomedical explanations concerning the kidneys, bones, and teeth. Through this approach, it can be demonstrated that TKM concepts remain valid in modern contexts, while also suggesting the potential to explain less clearly understood TKM theories in this manner.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.11
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• pp.4449-4454
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• 2014

Aim: Helicobacter pylori (H. pylori) have been considered as a risk factor for many cancers. We conducted this meta-analysis to clarify the association between H. pylori infection and the risk of pancreatic cancer. Methods: We searched the Medicine/Pubmed and Embase databases, studies about the association between H. pylori infection and pancreatic cancer published up to Jan.2014 were included. Finally, a total of 9 studies were used for this a meta-analysis. The odds ratios (ORs) and 95% confidence interval (95%CI) of H. pylori infection on pancreatic cancer with respect to control groups were evaluated. Two authors independently assessed the methodological quality and extracted data. This meta-analysis was conducted using software, state (version 12.0) to investigate heterogeneity among individual studies and to summarize the studies. Using the fixed-effects or random-effects model, depending on the absence or presence of significant heterogeneity. Sensitivity analysis was performed to assess the influence of each individual study on the pooled ORs by omitting a single study each time. Publication bias was evaluated by funnel plot, using Egger's and Begg's tests. Results: There was no significant association between H. pylori infection and pancreatic cancer risk in the summary ORs,(OR=1.06, 95%CI: 0.74-1.37) through the random-effect method, but heterogeneity among studies was significant ($I^2$=58.9%), so we put the studies into two subgraphs (eastern and western). The results about western (OR=1.14 95%CI:0.89, 1.40) showed heterogeneity among the western countries of $I^2$=6.6%, with no significant association between Hp+ and pancreatic cancer, but the eastern countries (OR=0.62, 95%CI:0.49, 0.76), $I^2$=0, suggested that decreasing pancreas-cancer risk in subjects with Hp+ infection. Simultaneously, 7 studies examined CagA+ strains was (OR=0.84 95%CI:0.63, 1.04), $I^2$=36% with the random-effect method, subgraphs indicated that CagA+ could decrease the risk of pancreatic cancer in the eastern subjects (OR=0.66, 95%CI:0.52-0.80), but the association was not statistically significant in the western subjects (OR=0.95, 95%CI:0.73, 1.16). Conclusion: Hp+ and CagA+ infection are associated with a decreased risk of pancreatic cancer in eastern populations but have no significant associations in western countries.

• Korean Journal of Oriental Medicine
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• v.15 no.1
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• pp.91-94
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• 2009

Understanding the present condition of Oriental traditional medicine in different country is demanded for the Korean Traditional Medicine to prepare his orientation in future. Also it is not possible to separate the present condition of OTM from history of oriental medicine as a whole. This is valid for the introduction of TCM in the west. The first information have arrived in Europe by the terrestrial and maritime travelers accounts. The diplomatic way, with special reference to Jesuit fathers, has brought cultural and theoretical precise data. The physicians of East India Company and, later, of expeditionary forces, have supplied with practical data. Five periods follow one another: 1) Period when the source reached and are used in Europe. This first step is intimately involved with the use and comparison of similar factor between the two medical systems ; 2) "Discovery" and use of needles ; 3) latent period when techniques coming from acupuncture source were developed ; 4) "Chinese Acupuncture" correctly speaking ; 5) modern period or investigating period, when Eastern and Western people are trying to correlate data of traditional medicine with those of western science. In particular the actual situation from 2000.

• Journal of Sasang Constitution and Immune Medicine
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• v.30 no.1
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• pp.1-6
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• 2018

In modern western science, the humanities and social sciences are separated from the natural sciences. However, new interpretations should be explored based on holistic concepts and the principles of wholeness found in eastern nature. Examples of the latter from Korea include Lee Je Ma's Sasang Constitutional Medicine(SCM). We aimed to examine the features and problems associated with SCM, as well as approaches to these problems. Sasang constitutional medicine suggests that an individual's constitution is determined congenitally, and the body and mind need to be considered simultaneously when treating disease. And SCM thinks that individuality is important in clinical practice even in social relationship. SCM needs to develop for objective diagnoses, and basic research needs to be conducted in parallel such as study of the Confucian classics and neo-confucianism. Expanding the scope of patient-centric academic exchange has been raised as an important issue to exchange with Western medicine and so on. SCM can be the medicine that places humanity at the center, and its mentality could apply to preventive medicine and personalized medicine. So it has positive influence on construction of a healthy society and improvement of healthcare worldwide.

• Journal of Korean Medical classics
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• v.28 no.1
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• pp.195-206
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• 2015

Objectives : Before Liver, Heart, Spleen, Lung, Kidney was widely accepted as Five Viscera, there had been several former types of Viscera system in pre-Western Han era. Above them, the Five Viscera system consisted of Liver, Heart, Stomach, Lung, Kidney was not yet hardly studied. So we tried to prove it's existence and tried to find it's historical context. Material and Methods : Via preceding research analysis, 6 books were selected as research material, and some other pre-Eastern Han dynasty classics were also analyzed. Results : We found direct evidence of above Five Viscera system in Zhuixingxun (墜形訓) in Huainanzi (淮南子), Wusemaizhen (五色脈診), and Western Han dynasty lacquer figure with meridian-points (excavated in Laoguanshan, Chengdu, China). Other clues showing existence of above Five Viscera system was also found in Yinyangshiyimaijiujing (陰陽十一脈灸經), Pianquecanggongliechuan (扁鵲倉公列傳). The rising of above Five Viscera system was related to physiological viewpoint transition of viscera in Western Han dynasty. Conclusions : In Western Han dynasty there was another Viscera System consisted of Liver, Heart, Stomach, Lung, Kidney.

• CELLMED
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• v.5 no.3
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• pp.15.1-15.12
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• 2015

Comparative studies have established that the North-Eastern (NE) region of India which is a part of the Eastern Himalayan region is affluent in both traditional knowledge based phytomedicine and biodiversity. About 1953 ethno-medicinal plants are detailed from the NE region of India out of which 1400 species are employed both as food and ethnopharmacological resources. Nearly 70% of species diversity has been reported from the two Indian biodiversity hotspots-The Western Ghats and the Eastern Himalayas and these hotspots are protected by tribal communities and their ancient traditional knowledge system. Paris polyphylla Smith belongs to the family Melanthiaceae and is a traditional medicinal herb which is known to cure some major ailments such as different types of Cancer, Alzheimer's disease, abnormal uterine bleeding, leishmaniasis etc. The major phytoconstituents are dioscin, polyphyllin D, and balanitin 7. Phylogeny of Paris was inferred from nuclear ITS and plastid psbA-trnH and trnL-trnF DNA sequence data. Results indicated that Paris is monophyletic in all analyses. Rhizoma Paridis, which is the dried rhizome of Paris polyphylla is mainly used in Traditional Chinese Medicine and its mode of action is known for only a few cancer cell lines. The current review determines to sketch an extensive picture of the potency, diversity, distribution and efficacy of Paris polyphylla from the Eastern Himalayan region and the future validation of its phytotherapeutical and molecular attributes by recognizing the Intellectual Property Rights of the Traditional Knowledge holders.

• Journal of Korean Medical classics
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• v.22 no.1
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• pp.71-85
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• 2009

For having good therapeutic value, putting the ideal of diagnosis and treatment based on overall analysis of symptoms and signs[辨證施治] into practice is very important, so the Eastern Medicine's peculiar diagnosis without interference by the western medical diagnosis is very important. The peculiar method of Eastern Medicine's diagnosis is four methods of diagnosis(四診法), a joint term for inspection, auscultation and olfaction, interrogation, pulse feeling and palpation. In the process of interrogation[問診], from analyzing the perspiration phase, doctor can get various physical information. Especially perspiration from particular region can be a clue for founding focus or cause of disease. This thesis divide the phase of perspiration into eight bodily region, perspiration from all body, head, face, back, chest and armpit, stomach, pubic region and lower part, hands and feet, and inquire the possible causes and principles of these perspirations. In conclusion, the regional perspiration can be a clue point out the origin of fever and condition of Gi(氣) flow. Perspiration from head, back, chest and armpit, hands and feet means that certain fever cannot extend to the outside of body, and at the same time, means the Gi(氣) flow of outside is being intercepted. So the perspirations from that region become an object of medical treatment.

• CELLMED
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• v.1 no.1
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• pp.1.1-1.7
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• 2011

Medicine has a past, a present, and will have a future; the same can be said for many diseases. Even with the surprising development of modern medicine, traditional medicine, especially eastern Asian traditional medicines still exist and are widely used in those regions. But modern medicine and western pacific traditional medicines have different theories and applications for the same disease. In this review, traditional medical theory, used together with modern medicine, can be combined to shed light on the area of neuronal death.

• Journal of Korean Medical classics
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• v.36 no.4
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• pp.109-130
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• 2023

Objectives : The Dong-hwa Yakbang Cheobangcheol, a formulary on proprietary medicines created by Dong-hwa Pharmacy in the early 20th century was analyzed with a focus on characteristics of the formulas that were made and sold at the time. Methods : First, external features such as bibliography, table of contents, and descriptive style were examined. In content, licensure of listed formulas, ingredients, dosage form, manufacturing process, effects, properties were medically and pharmacologically analyzed. In this process, the Japanese Pharmacopeial Convention, legislation related to medicinal pharmacology during Japanese Colonial Period, and the Donguibogam were referenced. Results : In terms of form, the Dong-hwa Yakbang Cheobangcheol faithfully follows medicinal related legislation established in the Japanese Colonial Period. However, in terms of content, we could see that most of the formulas were based on the Korean Medical tradition, while Western pharmaceutical technology and chemicals were selectively integrated when necessary. Conclusions : The Dong-hwa Yakbang Cheobangcheol comprehensively displays the situation and goal of Dong-hwa Pharmacy, one of the most representative pharmaceutical companies in proprietary medicine of the early 20th century, in which it was under pressure to adapt to power for survival, while it strived to help improve the health of the people of the time by adopting strengths of both Eastern and Western medicinals.

• Korean Journal of Oriental Medicine
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• v.14 no.2
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• pp.155-163
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• 2008

State Administration of Traditional Chinese Medicine of the People's Republic of China lead Research on Chao medicine's Constitutional Treatment project by which could involve the following principles. First, constitution can be identified, second, constitution correlates to ones susceptibility to diseases, third, constitution can be harmonized, fourth, prescription made according to ones constitution and patterns. These ideas is originated by Lee Je-ma's theory of Four Constitution Type in "DongEuiSooSeBoWon"(Longetivity and Life Preservation in Eastern Medicine). This is much similar to currents trends of personalized medicine in western medical sciences. Therefore further developing Lee's theory would have significant value on various fields of medicine.