• Asian Pacific Journal of Cancer Prevention
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• v.17 no.12
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• pp.5153-5157
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• 2016

Objective: The benefits of screening and early detection of breast cancer, including reduced morbidity and mortality, have been well-reported in the literature. In 2011, a breast cancer screening program was launched in Meknes-Tafilalt region of Morocco. The aim of this study was to evaluate the early performance indicators of this program. Materials and Methods: This retrospective evaluative study was conducted between April 2012 and December 2014, in Meknes-Tafilalt region of Morocco. Several performance indicators of the breast cancer screening program were calculated: the compliance rate, the positivity rate, the referral rate, the cancer detection rate and the organizational indicators. Results: During 2012-2014, a total of 184,951 women participated in the breast cancer screening program. The compliance rate was 26%, the positive rate was 3.3%, the referral rate was 36.7%, and the cancer detection rate was 1.2 per 1,000 women. The median time between the date of clinical breast examination and the date of biopsy (or cyto-puncture) was 36 days. The median time between the date of positive mammography and the date of biopsy (or cyto-puncture) was 6 days. The median time between the date of clinical breast examination and the date of the first received treatment was 61 days. Conclusions: The program needs better monitoring, as well as implementation of quality assurance tools to improve performance in our country.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2007.10a
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• pp.427-430
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• 2007

Many victims and property damages are caused in fires every year. In this paper, flame and smoke detection algorithm by using image processing technique is proposed to early alarm fires. The first decision of proposed algorithms is to check candidate of flame region with its unique color distribution distinguished from artificial lights. If it is not a flame region then we can check to candidate of smoke region by measuring difference of brightness and chroma at present frame. If we just check flame and smoke with only simple brightness and hue, we will occasionally get false alarms. Therefore we also use motion information about candidate of flame and smoke regions. Finally, to determine the flame after motion detection, activity information is used. And in order to determine the smoke, edges detection method is adopted. As a result of simulation with real CCTV video signal, it is shown that the proposed algorithm is useful for early fire recognition.

• Journal of the Korean Geographical Society
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• v.40 no.3 s.108
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• pp.285-295
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• 2005

This paper was examined distribution and changing trends on occurrence days of Spring Cold(cold surge in the flowering season) from the end of February to early in April during 1973-2004. We defined an occurrence day of Spring Colds as above $10\%$ of the anomalies of mean daily temperature or above $10\%$ of the difference of the daily mean temperature between the day before two days. In the west coastal region, the occurrence days of Spring Colds is higher in the end of February and less frequent in the early in April. In the east coastal region, the occurrence days of Spring Colds is higher in the early in April. Spring Colds is closely related with frequencies and a intensities of Siberian High. The occurrence days of Spring Colds has decreased in the most area except Ulleung island and the east coastal region.

• Proceedings of the Korea Concrete Institute Conference
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• 2003.05a
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• pp.463-468
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• 2003

A finite element formulation to predict the flexural behavior of composite girder is presented in which the early-age properties of concrete are specified including maturing of elastic modulus, creep and shrinkage. The time dependent constitutive relation accounting for the early-age concrete properties is derived in an incremental format by expanding the total form of stress-strain relation by the first order Taylor series with respect to the reference time. The total potential energy of the flexural composite member is minimized to derive the time dependent finite element equilibrium equation. Numerical applications are made for the 3-span double composite steel box girders which is a composite bridge girder filled with concrete at the bottom of the steel box in the negative moment region. The numerical analysis with considering the variation of concrete elastic modulus are performed to investigate the effect of it on the early-age behavior of composite structures. The one dimensional finite element analysis results are compared with the analytical method based on the sectional analysis. Close agreement is observed among the two methods.

• 한국방재학회:학술대회논문집
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• 2008.02a
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• pp.119-122
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• 2008

Recently, Geographical Information System (GIS) has been progressed in the fields of not only earth sciences and disaster problems, but also medical sciences, economical and social sciences. the southern region of Mid Niigata Region was attacked by intensive earthquake of M.6.8 on Richter Scale on October 23, 2004. The aim of this study was to improve efficiency of restoration operation for early victims relief. Significant issue is achieving the information processing required in restoration operation by spatial temporal information system.

• Journal of the Korea Fashion and Costume Design Association
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• v.6 no.2
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• pp.63-75
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• 2004

The traditional Ukrain costume has been gradually developed and influenced by the climate and political, economical environments. The national costumes has represented the beliefs and understanding of people about the beauty and harmony of the world. Eastern Europe and Northern Asia are considered as the origins of the Korean traditional costume, and the artifacts ranged from over the Black Sea to ‘Skitai’ and Northern Asia to ‘Noinoola’ support this hypothesis. This study is investigate the formative characteristics of Ukrain national costume especially of the nineteenth century and the early twentieth century. In Ukrain, Men wear ‘Rubaha’ (shirts style's upper garment-in Ukrain Sarochka) and trousers, women wear ‘Rubaha’ with vest and a skirt and a head gear were worn. Ukrain is consisted with three group - 1) Dnipro region-included the Kiev region in the center of Ukrain, 2) Polissia region in the northwest of Ukra in and 3) Hutsul-Zakarpattia region in the west of Ukrain. These three groups have there own different formative characteristics of Ukrain traditional costume.

• Reproductive and Developmental Biology
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• v.35 no.3
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• pp.281-285
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• 2011

In the present study, we identified differentially methylated region (DMR) upstream of Dnmt1o and Dnmt1s gene in early porcine embryos. Porcine Dnmt1o had at least one DMR which was located between -530 bp to -30 bp upstream from transcription start site of the Dnmt1o gene. DNA methylation analyses of Dnmt1o revealed the DMR to be hypomethylated in oocytes, whereas it was highly methylated in sperm. Moreover, the DMR upstream of Dnmt1o was gradually hypermethylated from oocytes to two cells and dramatically changed in the methylation pattern from four cells to BL stages in an in vivo. In an IVF, the methylation status in the DMR upstream of Dnmt1o was hypermethylated from one cell to eight cells, but demethylated at the Morula and BL stages, indicating that the DNA methylation pattern in the Dnmt1o upstream ultimately changed from stage to stage before the implantation. Next, to elucidate whether DNA methylation status of Dnmt1s upstream is stage-by-stage changed in during porcine early development, we analyzed the dynamics of the DNA methylation status of the Dnmt1s locus in germ cell, or one cell to BL cells. The Dnmt1s upstream was highly methylated in one and eight cells, while less methylated in two, four, morula, and BL cells. Taken together, our data demonstrated that DNA methylation and demethylation events in upstream of Dnmt1o/Dnmt1s during early porcine embryos dramatically occurred, and this change may contribute to the maintenance of genomewide DNA methylation in early embryonic development.

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.84-84
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• 2022

The limit of crop cultivation is moving northward due to the temperature rise by climate change. There is a problem with crop growth if early sowing is performed at a time when the temperature is low. It is difficult to secure crop productivity and cultivation stability due to the low temperature and short cultivation period. Therefore, this study was conducted to analyze the change in growth characteristics and yield of corn for grain when early sowing is performed in central region of South Korea. This experiment was conducted at experimental field of Suwon in 2021. Three varieties of corn for grain such as Kwangpyeongok, Sinhwangok, and Hwangdaok were sown at intervals of 5 days from 20 March to 15 April. The planting density at this time was sown with a row interval of 70 cm and a plant interval of 25 cm. Nitrogen, phosphoric acid, and potassium fertilizers were applied at 17.4 kg, 3.0 kg, and 6.9 kg per 10a, respectively. Phosphoric acid and potassium fertilizers were all applied before sowing and nitrogen fertilizer was applied 50% before sowing and 50% in the fifth leaf period. The corn growth characteristics and yield components were investigated. The seedling establishment rate by sowing date was in the range of 68.5~88.5%, and it showed a difference depending on the variety. The range of days from sowing to tassel and silk emergence by sowing date was 79.9~98.4 and 81.0~98.9 days, respectively. As the sowing date was delayed, the days from sowing to tassel and silk emergence decreased. The growth characteristics and yield of corn by sowing date are as follows. Plant height was the highest at 241.3 cm at the sowing on 25 March, and Stalk diameter was the thickest at 25.6 mm at the sowing on 31 March. The fresh weight per plant was the highest at 728 g at the sowing on 25 March, and the dry weight per plant was the highest at 185 g at the sowing on 31 March. Corn growth characteristics did not show a certain trend depending on the sowing date, and corn growth was more vigorous at the sowing on March 25 and 31 than the others. In the case of ear weight, it was the heaviest with 344 g at the sowing on 25 March, and filled ear length ratio showed a tendency to decrease as the sowing time was delayed. The weight of 100 grains and grain yield per 10a of maize were the highest at 36.0g and 878.7kg/10a, respectively at the sowing on 25 March. Although the growth and yield of corn for grain were good during early sowing in the central region of South Korea, it is necessary to investigate the limit temperature for early sowing of corn by examining the annual variation according to weather conditions.

• Journal of Korean Neurosurgical Society
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• v.57 no.4
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• pp.276-282
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• 2015

Objective : The purpose of this study was to investigate morphological change at the craniovertebral junction (CVJ) region using computed tomography. Methods : A total of 238 patients were included in this study, and mean age was $47.8{\pm}21.3months$. Spinal canal diameter, Power's ratio, McRae line, antero-posterior C1 ring height, atlantoaxial joint space, C2 growth, epidural space from the dens (M-PB-C2) and longitudinal distance (basion to C2 lower margin, B-C2) were measured. The mean value of each parameter was assessed for individual age groups. The cohorts were then divided into three larger age groups : infancy (I) (${\leq}2years$), very early (VE) childhood (2-5 years) and early (E) childhood ($5{\geq}years$). Results : Spinal canal diameter increased with age; however, this value did not increase with statistical significance after VE age. A significant age-related difference was found for all C2 body and odontoid parameters (p<0.05). Mean McRae line was 8.5, 8, and 7.5 mm in the I, VE, and E groups, respectively. The M-PB-C2 line showed up-and-down dynamic change during early pediatric periods. Conclusion : Expansion of the spinal canal was restricted to the very early childhood period (less than 5 years) in the CVJ region; however, the C2 body and odontoid process increased continuously with age. The above results induced a dynamic change in the M-PB-C2 line. Although C2 longitudinal growth continued with age, the McRae line showed relatively little change.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.697-702
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• 2016

Background: The Asia-Pacific Breast Initiatives (APBI) I and II registries were established to collect safety data for patients with early stage breast cancer receiving adjuvant docetaxel-based regimens in the Asia-Pacific region. Materials and Methods: Data from the two registries were combined to perform a safety analysis. Participants in the registry were women with early stage operable breast cancer with an intermediate or high risk of recurrence. These women received adjuvant chemotherapy that included docetaxel between 2006 and 2011. Adverse events (AEs) were recorded and analyzed. Results: Data were collected from 3,224 patients from 13 countries. The mean dose intensity of docetaxel was 24.1, 22.7, $25.1mg/m^2/week$ among patients receiving docetaxel-based monotherapy, combination therapy and sequential therapy, respectively. Granulocyte colony-stimulating factor (G-CSF) was given with docetaxel to 41.8% of women and 20.6% of women receiving prophylactic antibiotics. Adverse events were reported in 86% of patients (anthracycline-containing regimens vs. non-anthracycline regimens; 87% vs. 80%). The most common adverse events were alopecia, nausea, neutropenia, vomiting, and myalgia. Adverse events NCI CTCAE ${\geq}$Grade 3 were reported in 45.4% of patients. Serious adverse events were reported in 13% of patients, of which 2.5% led to study discontinuation. Forty-six deaths (1.4%) were reported, with no significant difference between regimens. Conclusions: The safety parameters of adjuvant docetaxel therapy used to treat sequential Asian women were comparable to those reported in clinical trials evaluating the role of adjuvant docetaxel. No unusual adverse events linked to Asia-Pacific region patients were observed.