• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.3 no.1
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• pp.93-97
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• 2000

We experienced a case of pathologic aerophagia in a 10-year-old girl who has mental retardation. It was observed that the abdomen was non-distended in the morning and became maximally distended in the evening. Increased passage of flatus, but normal eructation, was noted. Roentgenographic examination showed 'esophageal air sign', abnormal air shadow on proximal esophagus adjacent to the trachea, in simple chest X-ray and visible air swallowing fluoroscopically. We tried a percutaneous endoscopic gastrostomy (PEG) to decompress swallowed air in stomach. We suggest that placement of a PEG catheter in early life, especially in mentally retarded patients, that can be used as desufflator, can prevent the complications of aerophagia. 'Esophageal air sign' may be very helpful for early detection of pathologic aerophagia.

• Korean Journal of Ecology and Environment
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• v.46 no.1
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• pp.10-17
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• 2013

History of Instream Flow Incremental Methodology (IFIM) Following the large reservoir and water development era of the mid-twentieth century in North America, resource agencies became concerned over the loss of many miles of riverine fish and wildlife resources in the arid western United States. Consequently, several western states began issuing rules for protecting existing stream resources from future depletions caused by accelerated water development. Many assessment methods appeared during the 1960's and early 1970's. These techniques were based on hydrologic analysis of the water supply and hydraulic considerations of critical stream channel segments, coupled with empirical observations of habitat quality and an understanding of riverine fish ecology. Following enactment of the National Environmental Policy Act (NEPA) of 1970, attention was shifted from minimum flows to the evaluation of alternative designs and operations of federally funded water projects. Methods capable of quantifying the effect of incremental changes in stream flow to evaluate a series of possible alternative development schemes were needed. This need led to the development of habitat versus discharge functions developed from life stage-specific relations for selected species, that is, fish passage, spawning, and rearing habitat versus flow for trout or salmon. During the late 1970's and early 1980's, an era of small hydropower development began. Hundreds of proposed hydropower sites in the Pacific Northwest and New England regions of the United States came under intensive examination by state and federal fishery management interests. During this transition period from evaluating large federal reservoirs to evaluating license applications for small hydropower, the Instream Flow Incremental Methodology (IFIM) was developed under the guidance of the U.S. Fish and Wildlife Service (USFWS).

• Journal of the Korea Society of Computer and Information
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• v.26 no.8
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• pp.181-185
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• 2021

Road fine dust is not simply a problem of air pollution, but is threatening the health and life of the public, including pedestrians using sidewalks. There are various policy proposals related to road fine dust reduction, but the actual effect cannot be guaranteed. Therefore, in order to ensure the safe and pleasant passage of the people, the pavement pavement (sidewalk pavement) for fine dust management on the road should be designed by considering the location, use, function, etc., and appropriate paving materials and construction methods should be selected and designed or sidewalk facilities should be prepared. Therefore, this study examines the concept and legal basis of sidewalk pavement, reviews the status of sidewalk pavement-related technologies that purify air pollution, and utilizes sidewalk pavement materials under the revised sidewalk pavement guidelines for reducing fine dust, 「Act on Promotion of Purchasing of Green Products」 We intend to establish a legal basis for early application of sidewalk pavement technology by proposing measures and amendments to local government sidewalk pavement management rules.

• Strategy21
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• s.40
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• pp.115-130
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• 2016

The security environment surrounding the East Asian seas is rapidly changing due to the naval arms race among coastal states. The arms race is likely to worsen the security dilemma of the countries involved, thus increasing the chances for armed conflicts. It is too early to tell how the contemporary naval arms race in the region will evolve. But, for sure, the level of uncertainty is increasingly becoming high and intense. At the same time, there is emerging a legal warfare or lawfare among the rival countries. In particular, the United States and China have been involved in a serious debate about the nature and scope of the right of innocent passage and freedom of navigation in other countries' maritime zones. In collaboration with its regional allies, the United States has also put normative pressures on China with its excessive claims in the South China Sea. The latest arbitral tribunal case between the Philippines and China illustrates the point. With both arms race and normative competition in play, the future of East Asian maritime security will remain very complex and uncertain.

• Journal of Life Science
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• v.11 no.4
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• pp.362-370
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• 2001

Regulation of cell proliferation is a complex process involving the regulated expression and /or modification of discrete gene products. which control transition between different stages of the cycle. The purpose of this short review is to provide an overview of somatic cell cycle events and their controls. Cycline have appeared as major positive regulators in this network, because their association to the cyclin-dependent kinases(Cdks) allows the subsequent activation on the Cdk/cyclin complexes and their catalatic activity. In mammalian cells, early to mid G1 progression and late G1 progression leading to S phase entry are directed by D-type cyclins-Cdk4, 6 and cyclin E-Cdk 2 both of which can phosphorylate the retinoblastoma protein (pRB). pRB is a transcriptional repressor which, in its unphosphorylated state, binds to members of the E2F transcription factor family and blocks E2F-dependent transcription of genes controlling the G1 to S phase transition an subsequent DNA synthesis. Cyclin A is produced in late G1 and expressed during S and G2 phae, and expression of B-type cyclins is typically maximal during the G2 to M phase transition and it controls the passage through M phase. They primarily associate with the activate Cdk2, and Cdc2, respectively. On the other hand, the Cdk inhibitors negatively control the activity of C아/cyclin complex by coordinating internal and/or external signals and impending proliferation at several key checkpoints. These current and further findings will provide novel approaches to understanding and treating major diseases.

• Journal of Chest Surgery
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• v.35 no.1
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• pp.64-67
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• 2002

Eisenmenger's syndrome is the disease of right to left shunt developing from the increased pulmonary vascular resistance caused by excessive pulmonary blood flow in patients with abnormal connections of systemic to pulmonary blood passage. The heart-lung transplantation was the only curative method in early transplantation period, but good results after bilateral lung transplantation have been reported as the fact that right heart function improved by only lung transplantation. We successfully carried out bilateral sequential single lung transplantation in a 34-year-old female patient with Eisenmenger's syndrome with large PDA. We report this case with a brief review of the literature.

• International Journal of Highway Engineering
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• v.14 no.4
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• pp.1-8
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• 2012

PURPOSES : Skid resistance on pavements plays an important role in reducing the risk of vehicle skidding on wet surface particularly. Almost 9.3 percent of traffic accidents were occurred under rainy condition and these are over-represented in terms of the severity of the crashes. Recently, unusual weather conditions referred widely as the intensified rainfalls justify the need of a systematic management of skid resistance. In this context, the study carried out the observational study on the skid resistance characteristics of different types of pavement with the time passage. METHODS : This study measured the skid resistance with Pavement Friction Tester at three times within five years. The skid resistance measurement has followed the method suggested by ASTM. RESULTS : As the main results under the scope of this study, skid resistance of asphalt concrete has not nearly reduced with time. On the contrary, skid resistance of cement concrete has been rapidly reduced with time though the highest resistance was gained at the early observation. Porous asphalt concrete shows a steady decrease of skid resistance with time, anyway, the reduction rate according to the increase of measurement speeds is relatively lower than the others. CONCLUSIONS : Based on our study, skid resistance of the pavement should be regarded as one of the pavement management system, so periodic measurement should be made to assure road safety as a whole.

• Clinical and Experimental Reproductive Medicine
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• v.45 no.2
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• pp.75-81
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• 2018

Objective: Recapitulation of the spermatogenesis process in vitro is a tool for studying the biology of germ cells, and may lead to promising therapeutic strategies in the future. In this study, we attempted to transdifferentiate Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) into male germ cells using all-trans retinoic acid and Sertoli cell-conditioned medium. Methods: Human WJ-MSCs were propagated by the explant culture method, and cells at the second passage were induced with differentiation medium containing all-trans retinoic acid for 2 weeks. Putative germ cells were cultured with Sertoli cell-conditioned medium at $36^{\circ}C$ for 3 more weeks. Results: The gene expression profile was consistent with the stage-specific development of germ cells. The expression of Oct4 and Plzf (early germ cell markers) was diminished, while Stra8 (a premeiotic marker), Scp3 (a meiotic marker), and Acr and Prm1 (postmeiotic markers) were upregulated during the induction period. In morphological studies, approximately 5% of the cells were secondary spermatocytes that had completed two stages of acrosome formation (the Golgi phase and the cap phase). A few spermatid-like cells that had undergone the initial stage of tail formation were also noted. Conclusion: Human WJ-MSCs can be transdifferentiated into more advanced stages of germ cells by a simple two-step induction protocol using retinoic acid and Sertoli cell-conditioned medium.

• Journal of architectural history
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• v.25 no.2
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• pp.31-44
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• 2016

Imcheong-gak[臨淸閣] was a familial residence constructed in the early half of the Joseon dynasty period. It was partially destroyed by a fire during the 1590s war[壬辰倭亂] with the Japanese, and another fire that was caused between 1631 and 1634. The inner chamber[An-chae] and the Sarang section[Sarang-chae] today is the result of a partial reconstruction that took place back in 1626 and again around 1634. The residence also went through some changes because the new Ondol[溫突] heating system had to be applied to the structure. Based upon sections that remain in their original forms, we can presume that the Imcheong-gak residence originally had an inner chamber which was composed of the following elements: A main structure which was built upon a foundation featuring a Matbae[맞배] roof, two "Ik'rang[翼廊, flank]" sections on the East and West sides of the inner chamber, and a "Haeng'rang[行廊, passage]" structure on the opposite side of the main structure. Unlike the main structure, other portions of the inner chamber were all built directly upon the ground, and showed multiple stories, with Matbae roofs of their own. We can also assume that the Sarang section in the south would have been a pre-Ondol[溫突] bedroom, with a Board platform[板房] and a Gomi-ceiling[Gomi-banza] fashion.

• Solar Energy
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• v.9 no.1
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• pp.53-61
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• 1989

In the present investigation, experiments on the melting of a phase change material were performed to research heat transfer phenomena generated by means of conduction and natural convection in the vertical tube at inward melting. The phase change material used in the experiments is 99 percent pure n-Docosane paraffin which is measured melting temperature of $42.5^{\circ}C$, latent heat of 37.5 cal/g, heat conductivity of $0.1505W/m^{\circ}C$. Experiments were performed both in the no-subcooling which is initiating it at melting temperature of phase change material, and in the subcooling which means to initiate it under melting temperature of phase change material, in order to compare and investigate the horizontal temperature history, vertical temperature history, ratio of melting and melted mass, figure of the melting front in the vertical tube. In the experimental results, heat transfer from tube wall to phase change material were due to conduction at early stage and due to natural convection with the passage of time, and then occurred melting downward from surface by volumetric expansion. Natural convection affects temperature distribution in the tube, ratio of melting and melted mass, figure of the melting front and then progress rapidly in case of nosubcooling compared to subcooling.