• The Journal of Korean Physical Therapy
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• 제19권5호
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• pp.51-63
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• 2007

Diabetic foot ulcers result from abnormal mechanical loading of the foot, such as repetitive pressure applied to the plantar aspect of the foot while walking. Diabetic peripheral neuropathy causes changes in foot structure, affecting foot function and subsequently leading to increased plantar foot pressure, which is a predictive risk factor for the development of diabetic foot ulceration. To early identify the insensitive foot makes it possible to prevent diabetic foot ulceration and to protect the foot at risk from abnormal biomechanical loading. Abnormal foot pressures can be reduced using several different approaches, including callus debridement, prescription of special footwear, foot orthosis. injection of liquid silicone, Achilles tendon lengthening, and so forth. Off-loading of the diabetic wound is a key factor to successful wound healing as it is associated with reduced inflammatory and accelerated repair processes. Pressure relief can be achieved using various off-loading modalities including accommodative dressing, walking splints, ankle-foot orthosis, total contact cast, and removable and irremovable cast walkers.

• Journal of Plant Biotechnology
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• 제37권3호
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• pp.269-274
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• 2010

As the capture fishing industry has declined, the aquaculture industry has become an important source of seafood. With this tendency all fish farming will be performed by large-scale farms where the fish are cultivated in much high density and as a result the incidence of infectious diseases increases. Therefore, vaccination has become an increasingly important part of aquaculture as a cost effective method of controlling various diseases. The early fish vaccines were the formalin inactivated bacteria or virus cultures, which were administered by either immersion or injection. Recombinant DNA biotechnology allowed us to develop orally administrated DNA and recombinant vaccines. In terms of the manufacturing process and cost, Lemna and Spirodela is the most efficient and reliable plant expression system for the production of edible vaccine.

• The Korean Journal of Pain
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• 제21권1호
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• pp.66-70
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• 2008

Opioid-induced rigidity is a potentially life-threatening complication that can occur after treatment with large doses of opioids, but with early recognition it can be treated effectively with naloxone or with muscle relaxants. Regarding its onset time, there have been few case reports that have described delayed manifestations of opioid-induced rigidity. The mechanism of this complication is not well understood. In this report we describe a case of incidental overdose injection of sufentanil and subsequently review the confusing clinical features that require immediate diffenrentiation and the possible mechanim of this complication.

• Journal of Korean Neurosurgical Society
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• 제41권5호
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• pp.323-326
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• 2007

Direct carotid-cavernous fistula [CCF] is a common post-traumatic disease. However, pseudoaneurysm formation after balloon occlusion is a rare complication. The author present such a case with review of the literature. A 26-year-old man involved in a motor vehicle accident as a driver. Only mild conjunctival injection and minimal exophthalmos on the right eye were noted after trauma. However, angiography revealed a direct CCF and dissection of the proximal intracranial internal carotid artery [ICA]. After first balloon occlusion of the CCF, the patient redeveloped fistula due to early deflation of the balloon. After the second balloon occlusion, pseudoaneurysm and diplopia were developed with the change of balloon position and shape. However, visual symptom spontaneously resolved and pseudoaneurysm was also decreased within 6 months after balloon occlusion.

• 한국분무공학회지
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• 제13권2호
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• pp.65-72
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• 2008

It is recognized that alternative fuel such as dimethyl ether (DME) has better combustion polluting characteristics than diesel fuel, even though the cetane number of DME is almost the same as that of diesel. Characteristics of DME spray were observed experimentally under various ambient conditions using a constant volume chamber and a common-rail injection system. N-dodecane and LPG fuel sprays were also observed under same conditions of DME spray. Using spray images from backlight scattering and Mie scattering, characteristics of fuel sprays such as penetration and spray volume were visualized and quantitatively measured. The measurements showed that the penetration of early period decreased remarkably, because evaporation of alternative fuels became prosperous by the influence of flash boiling phenomenon under the condition of the low temperature and pressure compared with n-dodecane. The penetration of DME and LPG spray received the influence of temperature more largely in comparison with low density, because the specific surface area increased by atomizing in high density.

• Journal of Advanced Marine Engineering and Technology
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• 제26권5호
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• pp.554-564
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• 2002

A newly designed combustion chamber of diesel engine with a modified piston crown was prepared for the purpose of investigation for reduction of NO emission. It was intended to realize 2-stage combustion that is to keep fuel rich condition during early stage of combustion and fuel lean condition during next stage. The engine was tested on various conditions concerning exhaust gas emissions especially about NO emission and simultaneously fuel consumption rate. It was found that the engine with 2-stage combustion type piston emits significantly low NO at various speed and torque compared with conventional engines, but it raised points at issue in CO and smoke emissions with fuel consumption rate. The increasing of injection pressure on 2 stage combustion type diesel engine affects on CO and smoke emission considerably to reduce but slightly on NO to increase. The effect of 2-stage combustion was better at low speed than at high speed.

• KSBB Journal
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• 제11권1호
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• pp.107-114
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• 1996

당근세포(Daucus carota)로 부터 체세포배 생산성 증대를 위하여 체세포 배 현탁 배양액으로부터 추출한 세포외 분비물질을 이용하여 다음과 같은 효과를 측정하였다.: 분자량의 차이, 세포외 분비 물질 추출 시기, 주입시기, 주입농도에 따른 각종 체세포 배 생산성 증감 효과. 체세포배 생산량은 최대 1,500개/ml까지 얻었으며, 10kDa 이상 분자량이 포함된 세포외 분비물질을 초기에 주입시켰을 때 생산성이 특히 증가함을 보여 주었다.

• Asian-Australasian Journal of Animal Sciences
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• 제4권1호
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• pp.1-5
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• 1991

Responsiveness of the testis to pregnant mare's serum gonadotropin (PMSG) was studied in immature Nili-Ravi buffalo bulls. Four month old bull calves weighing between 66 to 100 kg raised under uniform condition, were treated with 1000 IU PMSG or vehicle, daily, for six days. PMSG induced an increase in the size of the testis, enlargement of the seminiferous tubules and activation of the spermatogonia. The number of differentiated Leydig cells in the testis of gonadotropin treated animals increased considerably over that of the control testes. A significant increase in plasma testosterone concentrations was observed 24 h following the first injection of PMSG and the levels continued to increase until day 6. In vehicle treated animals plasma testosterone levels remained more or less at pretreatment values. The data suggest that buffalo bull testis is functionally responsive to gonadotropin at an early stage of prepubertal development.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 1998년도 금형가공 심포지엄
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• pp.60-66
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• 1998

The horizontal cold chamber pressure die casting produces a variety of net shape, complicate-geometry castings with desired mechanical properties. dimensional tolerance, and surface finish. However, top quality castings can be achieved only when optimal performance of thecold chamber (shot sleeve )and plunger is maintained druing the molten metla injection phase of the process. Unforturately, inreality , shot sleeves deteriorate fast and sometimes fail catastrophically due to incorrect design. These early and unexpected failures of shot sleeves cost die casters money and productiivity. To prevent promature failures of shoe sleeves major faulure mechanisms were investigated. with the aid of analyticla solutions robust design criteria for shot sleeves have been developed. The data directly obtained from failed shot sleeves in the die casting industry for automotive parts, support a strong correlation between design and filures. by applying these design criterial we expected premature faulures of shot sleeves can be avoided in die casting industry.

• 한국자동차공학회논문집
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• 제2권4호
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• pp.100-111
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• 1994

Observations on the near-nozzle behavior of an unsteady fuel spray through single cylindrical hole nozzle were made by phase Doopler anemometer and microphotographs. At the edge of the spray, droplet velocity peaked during needle opening and closing. Droplet sizes tended to be small on the edge of spray. The near-nozzle spray angle taken from the microphotographs was time-dependent, even though it increased with gas-to-liquid density ratio as expected. The near-nozzle spray angle was the greatest on the initial stage and decreased to a relatively constant value after about one third of the total injection duration regardless of the ambient gas conditions, even in the near-vaccum condition. The wider near-nozzle spray angle in the early stage is due to the flow characteristics inside the nozzle rather than aerodynamic interactions. However, once the spray was established, aerodynamic interactions are essential in the near-nozzle atomization.