• Title/Summary/Keyword: Early Failure

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Cardiac biomarkers for early detection of heart diseases in small animals

  • Hyun, Chang-Baig
    • Proceedings of the Korean Society of Veterinary Clinics Conference
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    • 2009.04a
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    • pp.137-150
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    • 2009
  • Background: Heart failure can develop secondary to various heart diseases (e.g. mitral valvular insufficiency, congenital heart defects, heart worm infection). The clinical signs of heart failure can be confused with those of other conditions, such as respiratory disease. Therefore, specific, sensitive, rapid and inexpensive blood tests for heart failure are desirable. Cardiac troponins, natriuretic peptides and cytokines have been more recently used as indicators of heart disease in humans and animals. These peptides are sensitive to changes in vasoconstriction and dilation within the heart and are used for the diagnosis and prognosis of heart failure. Methods: Previously developed and newly developed cardiac biomarkers will be discussed for understating clinical implications and diagnostic values in heart diseases in small animals

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Urinary Change of Kallikrein in Adenine-Induced Renal Failure Rat (Adenine 유발 신부전 흰쥐에서의 뇨중 Kallikrein의 변화)

  • Lee, Tae-Woong;Seo, Suk-Soo;Lee, Kyung-Hee;Young, Han-Suk;Chung, Joon-Ki;Choi, Jae-Sue
    • YAKHAK HOEJI
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    • v.35 no.6
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    • pp.504-508
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    • 1991
  • In order to investigate whether the function of distal nephron is disturbed in adenine-induced renal failure rats, we measured the urinary kallikrein level in adenine-ingesting rats fed on 0.75% adenine diet for 1 to 10 days. Administration of 0.75% adenine to rats significantly increased blood urea nitrogen level and urine volume, while the level of kallikrein along with the urinary excretions of urea and inorganic phosphate were significantly decreased. From these results, it is suggested that adenine-induced renal failure is caused by early deterioration of distal nephron as well as proximal nephron.

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A Case of Hair Neutralizer Induced Non-oliguric Acute Renal Failure (파마중화제에 의한 비핍뇨성 급성신부전 1례)

  • Kim Ah Jin;Kim Kyung Hwan;Park Jun Seok;Shin Dong Wun
    • Journal of The Korean Society of Clinical Toxicology
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    • v.3 no.2
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    • pp.119-121
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    • 2005
  • Sodium bromate or potassium bromate has been used as hair cold neutralizer. Sodium bromate intoxications occurred in children incidentally early days of marketing, but recently in adult suicidally. This chemical intoxication result in renal failure, ototoxicity, neurotoxicity, hemolytic anemia and so on. We experienced a 39-year-old woman of hairdresser with non-oliguric acute renal failure after ingestion hair neutralizer 500 ml. She received hemodialysis 3 times and discharged without complication on 8th admission days.

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Discussion on safety counter-plan and failure characteristics of customer switches (수용가용 개폐기의 사고 특성과 안전대책 검토)

  • Lee, Hae-Ki;Yoo, Young-Kag;Kang, Seong-Hwa
    • Proceedings of the KIEE Conference
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    • 2006.10b
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    • pp.204-207
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    • 2006
  • Prevention of electrical and mechanical accidents from consumer switches needs early to detect and repair failure parts of the switches. But, safety accidents by the switches of consumers occur from non-systematic safety inspection techniques. So, we develope and propose the safety inspection techniques of the consumer switches.

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Complete trisomy 14 mosaicism: first live-born case in Korea

  • Hur, Yun Jung;Hwang, Taegyu
    • Clinical and Experimental Pediatrics
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    • v.55 no.10
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    • pp.393-396
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    • 2012
  • Trisomy 14 mosaicism is a rare chromosome disorder characterized by delayed development, failure to thrive, and facial dysmorphism. Only approximately 30 trisomy 14 mosaicism cases have been reported in the literature because trisomy 14 is associated with early spontaneous abortion. We report a case of a 17-month-old girl with abnormal skin pigmentation, delayed development, facial dysmorphism, and failure to thrive with the 47,XX,+14/46,XX chromosome complement.

Failing the Game Quests in James Joyce's "Araby"

  • Jang, Sungjin
    • Journal of English Language & Literature
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    • v.64 no.3
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    • pp.403-414
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    • 2018
  • This paper suggests a different reading of James Joyce's "Araby" by offering the video game as a lens through which we can reimagine the story. Understanding the unnamed boy's journey to the Araby bazaar as a fetch quest, this paper focuses on the boy's failure to complete this quest. As soon as the boy promises Mangan's sister something from Araby, his fetch quest begins. In order to complete the quest, the boy must successfully perform three sub-quests: get money from his uncle as early as he can, get on the train for the Araby bazaar on time, and pass through the sixpenny entrance at the bazaar. However, because his uncle comes home late, the boy fails to get the money early, and that sets off the subsequent failures. The boy then takes the train late and arrives at the bazaar so late that he feels he must go through any entrance. So he walks through the adult entrance by mistake. As a result, he does not have enough money to buy a gift, failing the larger quest. But, regardless of this failure, the boy can try these quests as many as he wants until he finally succeeds in completing them. But no matter how the boy tries to accomplish these subquests, he is doomed to fail them because he cannot make his uncle come home early. The more he tries his quest, the more bitterly he realizes that he will ultimately fail. In this respect, the boy's "anguish and anger" should be understood as his epiphany: the re-playability of the game is possible, but all the replays lead to the same failure: losing the game. In this regard, reading Joyce's "Araby" is much like playing a video game.

Economic Design of $\bar{X}$-Control Charts with Warning Limits under Weibull Failure Model (와이블 고장모형 하에서 경고한계를 고려한 $\bar{X}$ 관리도의 경제적 설계)

  • Jeong, Dong-Wook;Lee, Joo-Ho
    • Journal of Korean Society for Quality Management
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    • v.40 no.2
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    • pp.186-198
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    • 2012
  • Since Duncan(1956) first proposed an economic design of $\bar{X}$-control charts, most of the succeeding works on economic design of control charts assumed the exponential failure model like Duncan. Hu(1984), however, assumed a more versatile Weibull failure model to develop an economic design of $\bar{X}$-control charts and Banerjee and Rahim(1988) further improved Hu's design by changing the assumption of fixed-length sampling intervals to variable-length ones. In this article we follow the approach of Banerjee and Rahim(1988) but include a pair of warning limits inside the control limits in order to search for a failure without stopping the process when the sample mean falls between warning and control limits. The computational results indicate that the proposed model gives a lower cost than Banerjee and Rahim's model unless the early failure probability of a Weibull distribution is relatively large. The reduction in cost is shown to become larger as the cost of production loss outweighs the cost of searches for a failure.

Failure Analysis of Underground Transmission Cable Systems (국내 지중 케이블 고장현황 분석)

  • Kang, Y.W.;Cho, S.B.;Kwak, B.M.;Lim, H.E.;Yoon, H.H.
    • Proceedings of the KIEE Conference
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    • 1999.07e
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    • pp.2377-2379
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    • 1999
  • In order to analyze failure rates of underground transmission power cable systems in Korea, the survey has been performed for the failure cases of cables, joints, and terminations in CV, OF and POF cable systems which occurred from 1983 to 1998. During 16 years, the failure cases due to trips of the systems were 47 among the total 108 cases, These 47 cases could be divided into internal reasons(manufacture/installation, corrosion and degradation) of 16 cases and external reasons (external mechanical damages, lightning, fire. etc.) of 31 cases. For the 154 kV cable systems during 12 years from 1987 to 1998, total failure rate was 0.0057 [case/100C-km/year] and internal reason failure rate was 0.0020 [case/100C-km/Year], which is similar to those of foreign countries. Also, the many cases of internal reason failures occurred in the early stage after the operations due to incorrect installations. This implies that the installation process is very important and some diagnostic tests such as PD measurement are needed besides after laying test.

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Two Cases of Fatal Paraquat Intoxication by Parenteral Injection (비경구적 투여에 의한 치명적인 파라캇 중독증 2례)

  • Kim, Dong-Hoon;Lee, Kyung-Woo
    • Journal of The Korean Society of Clinical Toxicology
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    • v.5 no.2
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    • pp.119-122
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    • 2007
  • Paraquat poisoning is a fatal type of herbicide intoxication. It is characterized by multi-organ failure and pulmonary fibrosis with respiratory failure. Intravenous and intramuscular injection of paraquat is rarely described. However, We encountered two fatal cases of acute poisoning caused by paraquat injection. Two patients were admitted to our emergency unit after intravenous and intramuscular injection of 23.8% paraquat (about 476 mg of paraquat). A 37-year-old man diluted 2 ml of 23.8% paraquat solution with 1 ml of normal saline and injected it both intravenously into his left antecubital fossa and intramuscularly into his abdomen in a suicide attempt. He died 5 days later from respiratory failure and acute renal failure. A 92-year-old man was injected intravenously into his right antecubital fossa by his grandson with 2 ml of 23.8% paraquat solution diluted with 1 ml of normal saline. He died 2 days later from early circulatory collapse and multi-organ failure (metabolic acidosis, acute renal failure, coagulopathy). Intravenous and intramuscular injection with a small quantity of paraquat resulted in fatal toxicity in our patients.

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Cluster and information entropy analysis of acoustic emission during rock failure process

  • Zhang, Zhenghu;Hu, Lihua;Liu, Tiexin;Zheng, Hongchun;Tang, Chun'an
    • Geomechanics and Engineering
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    • v.25 no.2
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    • pp.135-142
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    • 2021
  • This study provided a new research perspective for processing and analyzing AE data to evaluate rock failure. Cluster method and information entropy theory were introduced to investigate temporal and spatial correlation of acoustic emission (AE) events during the rock failure process. Laboratory experiments of granite subjected to compression were carried out, accompanied by real-time acoustic emission monitoring. The cumulative length and dip angle curves of single links were fitted by different distribution models and distribution functions of link length and directionality were determined. Spatial scale and directionality of AE event distribution, which are characterized by two parameters, i.e., spatial correlation length and spatial correlation directionality, were studied with the normalized applied stress. The entropies of link length and link directionality were also discussed. The results show that the distribution of accumulative link length and directionality obeys Weibull distribution. Spatial correlation length shows an upward trend preceding rock failure, while there are no remarkable upward or downward trends in spatial correlation directionality. There are obvious downward trends in entropies of link length and directionality. This research could enrich mathematical methods for processing AE data and facilitate the early-warning of rock failure-related geological disasters.