• 한국작물학회지
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• 제65권4호
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• pp.477-484
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• 2020

This study was conducted to investigate the effects of slow-releasing fertilizer and sowing date on waxy corn propagated through double cropping without tillage. "Mibaek 2" was sown for first cropping on March 25^th, April 5^th, and April 15^th, and for second cropping on July 5^th, July 15^th, and July 25^th in 2018-2019. In order to save labor, slow-releasing fertilizer was utilized only one time before sowing. The accumulated temperature from sowing to silking was about 590-700℃. It took 65-77 days when "Mibaek 2" was sown in early April, but the one sown in early July took 42-52 days. In the first cropping, the culm length and ear length caused by the sowing date had no statistical significance, but the kernel set length was the highest at 123 cm in the sowing district on April 5^th. The weight of marketable ears was the highest at 100%, in addition to soil testing-based recommended fertilization. Meanwhile, in the second cropping, culm length, ear length, and yield were less compared to the first cropping. The culm length, kernel set length, ear length, and seed set length decreased as sowing date was delayed. The number and yield of marketable ears were the highest at 100%, in addition to soil testing-based recommended fertilization like in the first cropping. It has been found that securing yield by July 15^th to finish the second seeding of the crop in the central part of Korea is advantageous. These results of this study will be helpful to farmers for the double cropping of waxy corn cultivation and management.

• 한국해안해양공학회지
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• 제12권4호
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• pp.168-180
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• 2000

In the Part I, the three dimensional model testing with NNW deep water wave direction gave the results such that the occurrence of breaking waves over the peak of Ear-Do caused very small wave height at the structure position. But the measured wave forces were rather greater than the calculated forces based on deep water wave height. Furthermore, It was also perceived that the time series of the forces looked like corresponding to the case that waves were superimposed by an unidirectional current. In the present Part II, the current is presumed to be a flow secondly induced by breaking waves, and an extensive study to clarify the current in a quantitative sense is performed through numerical analysis and hydraulic experiment. The results showed that a strong circulation can surely occur in the vicinity of the structure due to radiation stress differentials given by the breaking waves. It was also recognized that the velocity of the induced current varied with the magnitude of energy dissipation rate introduced in the numerical analysis. The numerical analysis was tuned adjusting the dissipation rate so that the calculated wave field could closely match with the experimental results of Part I. The fluid force (in prototype) for the optimal match showed approximately 2.2% increased over the calculated value based on the deep water wave height (24.6m) whereas the force corresponding to the average of the experimental values showed the increase of about 13.0%.

• 음성과학
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• 제11권3호
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• pp.175-180
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• 2004

In case of the hearing impairment with tinnitus and increased sound sensitivity, it is known that the patients tend to appeal the psychologically oriented social handicap rather than communication disability. The audiologist who is responsible for such patients in aural rehabilitation should pay special attention to the counseling techniques including tinnitus retain therapy (TRT), ear protector, noise generator, or specific acoustic training based on close cooperation and rapport. And then the audiologist should try to lessen their reaction to the tinnitus by using a hearing aid. This therapies tries to focus not a. total approach but a treatment to lessen the severity of tinnitus. This paper as a case report that a unilateral sharply slopped sensorineural hearing impaired person with tinnitus and increased sound sensitivity by using four channel digital signal processing (DSP) hearing aid with programming increment at low level (PILL).

• 한국임상수의학회지
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• 제21권2호
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• pp.187-190
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• 2004

A mixed case of multiple sebaceous gland adenoma and perianal gland adenoma was found in a 11-year-old male Shih Tzu dog. Grossly, many masses less than 1 cm in diameter of back skin and single red-brown mass about 0.5 cm in diameter of inner ear were noted. In addition one of light-pink mass 5 cm in diameter was presented in the anus. All of the masses were well demarcated and dome-shaped or papillated nodules. Histologically, the mass from back and ear were composed with multiple irregular shaped or sized lobules of sebaceous glands. Masses were containing mostly mature sebaceous cells and multifocal cystic degeneration with acellular and bright eosinophilic materials. And the mass from peri-anal area was well-circumscribed and composed of broad, anastomosing trabeculae of well-differentiated hepatoid cells. There were very low mitotic figures in all masses. Based on these results, this case was diagnosed as the multiple sebaceous gland adenoma and perianal gland adenoma.

• Journal of Plant Biotechnology
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• 제49권1호
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• pp.3-14
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• 2022

Leonotis nepetifolia (L.) R. Br, commonly called dagga, klip dagga, or lion's ear, has been used to effectively treat various diseases and other health problems for a long time because of its antimicrobial, anti-inflammatory, antioxidant, and analgesic activities. Several studies have attributed these biological activities to L. nepetifolia's constituent secondary metabolites, such as alkaloids, phenolics, flavonoids, tannins, steroids, glycosides, coumarins, anthocyanins, and saponins. This review aims to examine the evidence-based ethnopharmacological uses of L. nepetifolia in the treatment of bronchial asthma, diarrhea, skin diseases, malaria, burns, cancer, diabetes mellitus, and rheumatism. However, although L. nepetifolia has great potential to treat these diseases, further isolation and identification of its therapeutic phytochemical constituents are required. In addition, the performance of its extracts and phytochemicals should be thoroughly tested in preclinical and clinical trials in order to ascertain their safety and efficacy, which will prove valuable in developing new medicines.

• Journal of Nutrition and Health
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• 제55권1호
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• pp.10-20
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• 2022

2020 한국인 영양소 섭취기준 개정에서 단백질은 기본적으로 질소평형을 유지하는데 필요한 단백질 양 0.66 g/kg 체중/일에 이용효율 90%를 적용한 평균필요량 0.73 g/kg 체중/일과 변이계수 12.5%를 적용한 권장섭취량 0.91 g/kg 체중/일을 생애주기별 체위기준치 변화에 따라 제시하였다. 그러나 성장기의 단백질 섭취기준에서는 체중 기준을 2017년에 개정된 소아청소년 성장도표에 근거하고, 일본 DRI 자료를 참고로 단백질 식품 이용효율을 차등 적용하였으며, WHO/FAO/UNU 보고서상의 성장에 필요한 단백질량 오류를 수정·반영하여 기준값을 개정하였다. 그 결과 일부 연령구간에서 섭취기준의 상향조정이 있었으나 한국인의 연령대별 1일 평균 단백질 섭취량은 대부분의 연령대에서 단백질 평균필요량의 100%를 넘는 것으로 나타났고, 남자 75세 이상과 여자 65세 이상을 제외하고는 권장섭취량과 비교했을 때도 많은 것으로 나타나 단백질 섭취기준의 상향 조정은 국민의 평균 단백질 섭취기준을 반영하는 것으로 판단된다. 한편, 75세 이상의 단백질 섭취량은 근감소증 예방, 근력 강화 등을 위해 65-74세 단백질 섭취기준과 동일하게 설정하였다. 이번 개정에서 단백질 에너지 적정비율은 기존의 7-20%를 유지하였으나 향후 단백질의 적정한 섭취수준 및 만성질환예방을 위한 단백질 필요량 설정에 관한 과학적 근거마련을 위해 우리나라 국민을 대상으로 한 다양한 중재연구가 수행되어야 할 것이다.

• Fibers and Polymers
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• 제6권3호
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• pp.219-223
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• 2005

Water-soluble chitin (WSC) was prepared by carefully deacetylating chitins to about $50\%$ of N-acetyl content. Topical formulations based on WSC were prepared and their effects on wound healing were evaluated on a rabbit ear model. Full-thickness, open skin wounds were made on the ears of rabbits and WSC ointments were embedded in the open wounds. The application of WSC ointments significantly accelerated wound healing and wound contraction. The areas of epithelial-ization and granulation tissues in WSC ointment group are remarkably larger than those in control group (no treatment) and in placebo group (treated with ointment-base materials). A large number of grown granulation tissues including dense fibroblast deposition were observed under the thickened epithelium of the wound treated with WSC ointments. The number of inflammatory cells in WSC ointment group was significantly decreased compared with those in control and placebo groups, indicating that WSC would give low stimuli to wounds and prevent excessive scar formation. Neovascularization was the most prominent in WSC ointment group. Wound contraction in WSC ointment group was much larger than those in control and placebo groups. Overall results demonstrate that the topical formulation based on WSC is considered to become an excellent dressing as a wound healing assistant.

• 대한의용생체공학회:의공학회지
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• 제41권1호
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• pp.22-27
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• 2020

Auditory stimuli are commonly used in various electroencephalogram experiments, also in EEG-based brain-computer interface systems. However, using conventional earphones that blocks the ear canal attenuates or even blocks external environmental sound which might cause loss of crucial information from surroundings. Instead, bone-conductive earphones are able to deliver sound through vibration without blocking the ear canal. To investigate the feasibility of the bone-conductive earphones for auditory-stimuli based experiments, we compared N100 event-related potential features as well the event-related spectral perturbation and inter-trial coherence of auditory steady-state response between conventional and bone-conductive earphones. The results showed no significant differences between bone conduction and conventional earphones regardless of distinct sound pressures. This result shows that bone conductive earphones can be used for auditory experiments when the environmental sound is crucial to the user.

• 대한본초학회지
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• 제25권4호
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• pp.11-16
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• 2010

Objective : Oriental medicines have been combined oriental medical theory which based on the seven modes of emotions. Notopterygium incisum (N. incisum) and Clematis manshurica (C. manshurica) have been used as an anti-rheumatic and analgesic medicine for the treatment of rheumatism, headache, cold, etc. In this study, we evaluate the synergistic anti-inflammatory effect of N. incisum and C. manshurica. Method : To evaluate the synergistic anti-inflammatory effect of a herbal mixture N. incisum and C. manshurica, we examined the changed ear thickness in 12-O-tetradecanoyl-phorbol-13-acetate (TPA)-induced mouse ear edema model after topical application of herbal mixture. In addition, the levels of markers for inflammation, such as tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-$1{\beta}$, prostaglandin $G_2$ ($PGE_2$), and nitric oxide (NO) were measured by ELISA assay and Griess reagent in lipopolysaccharide-stimulated Raw 264.7 cells. Results : Our results showed that aqueous extracts of N. incisum and C. manshurica combination significantly inhibited the mouse ear edema induced by TPA. Moreover, the aqueous extracts of N. incisum and C. manshurica combination exhibited synergistic effects in down-regulating TNF-${\alpha}$, IL-$1{\beta}$, $PGE_2$ level, but not NO. Conclusions : This study suggested that combined treatment of N. incisum and C. manshurica, based on seven methods in prescription compatibility, has a synergistic effect in down-regulating inflammatory response both in vitro and in vivo models.

• Archives of Plastic Surgery
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• 제46권6호
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• pp.525-534
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• 2019

Background In microtia patients with bilateral hearing impairment, hearing improvement is crucial for language development and performance. External auditory canal reconstruction (EACR) has been performed to improve hearing, but often results in complications. We performed transcutaneous bone conduction implant (TBCI) surgery in these patients. This study aimed to evaluate the safety and efficacy of TBCI surgery. Methods A retrospective review was performed of five patients who underwent auricular reconstruction and TBCI surgery and 12 patients who underwent EACR between March 2007 and August 2018. Hearing improvement was measured based on the air-bone gap values using pure-tone audiometry over a 6-week postoperative period. We reviewed other studies on hearing improvement using EACR and compared the findings with our results. The surgical techniques for TBCI were reviewed through case analyses. Results Postoperative hearing outcomes showed a significant improvement, with a mean gain of 34.1 dB in the TBCI cohort and 14.1 dB in the EACR cohort. Both gains were statistically significant; however, the TBCI cohort showed much larger gains. Only three of the 12 patients who underwent EACR achieved hearing gains of more than 20 dB, which is consistent with previous studies. All patients who underwent TBCI surgery demonstrated hearing gains of more than 20 dB and experienced no device-related complications. Conclusions TBCI is a safe and effective method of promoting hearing gains in microtia patients with bilateral hearing impairment. TBCI surgery provided better hearing outcomes than EACR and could be performed along with various auricular reconstruction techniques using virgin mastoid skin.