• 멤브레인
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• 제32권2호
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• pp.116-125
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• 2022

본 실험에서는 α-Al₂O₃ 세라믹 중공사를 지지체로 사용하였고, 무전해 도금을 통해 Pd 및 Pd-Ag가 도금된 수소 분리막을 제조하였다. Pd-Ag 분리막은 Pd와 Ag 합금 형태로 만들기 위하여 500℃, 10 h 동안의 annealing 과정을 거쳤으며, EDS (Energy Dispersive X-ray Spectroscopy) 분석을 통해 Pd-Ag 합금이 되었다는 것을 확인하였다. 또한, SEM (Scanning Electron Microscope) 분석을 통해 제조된 Pd 및 Pd-Ag 도금층의 두께는 약 8.98, 9.29 ㎛으로 측정되었다. 제조된 수소 분리막은 350~450℃, 1-4 bar의 범위에서 수소 단일 가스, 혼합가스(H₂, N₂)를 이용하여 수소 투과 실험을 진행하였다. 수소 단일 가스에서 Pd와 Pd-Ag 분리막은 최대 각각 21.85, 13.76 mL/cm²·min의 flux를 가지며, 혼합가스에서는 450℃, 4 bar의 조건일 때, 1216, 361의 separation factor가 각각 나오는 것을 확인하였다.

• 인간식물환경학회지
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• 제23권6호
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• pp.637-646
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• 2020

Background and objective: The main objective of this study is to measure the amount of particulate matter (PM) reduction under different characteristics of leaves in 18 different species of indoor plants. Methods: First, a particular amount of PM was added to the glass chambers (0.9×0.86×1.3 m) containing the indoor plant (height = 40 ± 20 cm), and the PM concentration were measured at 2-hour intervals. The experiment with the same conditions was conducted in the empty chamber as the control plot. Results: The range of PM reduction per unit leaf area of 18 species of experimental plants was 3.3-286.2 ㎍·m^-2 leaf, total leaf area was 1,123-4,270 cm², and leaf thickness was 0.14-0.80 mm and leaf size 2.27-234.47 cm². As time passed, the concentration of PM decreased more in the chamber with plants than in the empty chamber. Among the 18 indoor plants, the ones with the greatest reduction in PM2.5 in 2 hours and 4 hours of exposure to PM2.5 were Pachira aquatica and Dieffenbachia amoena. As the exposure time of PM increased, the efficiency of reducing PM2.5 was higher in plants with medium-sized leaves than plants with large or small leaves. The effect of reducing PM2.5 was higher in linear leaves than round or lobed leaves. Plants with high total leaf area did not have advantage in reducing PM because the leaves were relatively small and there were many overlapping parts between leaves. In the correlation between leaf characteristics and PM 2.5 reductions, all leaf area and leaf thickness showed a negative and leaf size showed a positive correlation with PM reduction. Conclusion: The PM reduction effect of plants with medium-sized leaves and long linear leaves was relatively high. Moreover, plants with a large total leaf area without overlapping leaves will have advantaged in reducing PM. Plants are effective in reducing PM, and leaf characteristics are an important factor that affects PM reduction.

• 한국구조물진단유지관리공학회 논문집
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• 제26권6호
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• pp.167-174
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• 2022

이 연구의 목적은 감쇠능력이 우수한 재료로 구성된 DUS(damping-up system)의 동적특성을 평가하고 일반 행어볼트와의 성능을 비교하는데에 있다. 주요변수는 고무의 종류 및 경도(𝜂_H) 그리고 프리스트레스력(고무의 응력-변형률 관계에서 압축변형률(𝜂_R)로부터 환산된 값)이다. 동적특성은 고유진동수(𝜔_n), 최대 응답가속도(A_m), 증폭계수(𝛼_p), 최대 상대변위(𝚫_m) 및 감쇠비(𝜉_D)로부터 평가되었다. 실험결과 DUS의 A_m, 𝛼_p 및 𝚫_m 는 일반 행어볼트 보다 각각 46.3%, 46.6% 및 62.9% 낮았으며, 𝜉_D는 3.89배 높았다. 특히 DUS의 𝛼_p 는 평균 1.3으로서 KDS 41 17 00의 강성요소에서 제시하는 값과 비슷한 반면, 일반 행어볼트의 𝛼_p 는 2.45로 연성요소에서 제시하는 값과 비슷하였다. 결과적으로 DUS의 최적상세는 𝜂_H가 50인 NR(natural rubber)과 45인 EPDM(ethylene propylene diene monomer)을 권장하며, 이들의 𝜂_R는 5%로 추천한다.

• Journal of Animal Science and Technology
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• 제64권1호
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• pp.166-182
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• 2022

Deer antler velvet is widely used in traditional medicine for its anti-aging, antioxidant, and immunity-enhancing effects. However, few studies have reported on the discovery of probiotic strains for deer antler fermentation to increase functional ingredient absorption. This study evaluated the ability of probiotic lactic acid bacteria to enhance the concentrations of bioactive molecules (e.g., sialic acid and gamma-aminobutyric acid [GABA]) in extracts of deer antler velvet. Seventeen strains of Lactobacillus spp. that were isolated from kimchi and infant feces, including L. sakei, L. rhamnosus, L. brevis, and L. plantarum, and those that improved the life span of Caenorhabditis elegans were selected for evaluation. Of the 17 strains, 2 (L. rhamnosus LFR20-004 and L. sakei LFR20-007) were selected based on data showing that these strains increased both the sialic acid and GABA contents of deer antler extract after fermentation for 2 d and significantly improved the life span of C. elegans. Co-fermentation with both strains further increased the concentrations of sialic acid, GABA, and metabolites such as short-chain fatty acids and amino acids. We evaluated the biological effects of the fermented antler velvet (FAV) on the antibacterial immune response in C. elegans by assessing worm survival after pathogen infection. The survival of the C. elegans conditioned with FAV for 24h was significantly higher compared with that of the control worm group fed only normal feed (non-pathogenic E. coli OP50) exposed to E. coli O157:H7, Salmonella typhi, and Listeria monocytogenes. To evaluate the protective effects of FAV on immune response, cyclophosphamide (Cy), an immune-suppressing agent was treated to in vitro and in vivo. We found that FAV significantly restored viability of mice splenocytes and immune promoting-related cytokines (interleukin [IL]-6, IL-10, inducible nitric oxide synthase [iNOS], interferon [IFN]-γ, and tumor necrosis factor [TNF]-α) were activated compared to non-fermented deer antlers. This finding indicated the protective effect of FAV against Cy-induced cell death and immunosuppressed mice. Taken together, our study suggests that immune-promoting antler velvet can be produced through fermentation using L. rhamnosus LFR20-004 and L. sakei LFR20-007.

• 보존과학회지
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• 제38권3호
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• pp.180-191
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• 2022

목조문화재의 대부분은 외부 환경에 그대로 노출되어 있어 위치와 크기에 의해 보존에 관련하여 많은 어려움을 가지고 있다. 그중 흰개미나 곰팡이에 의해 발생하는 생물학적 피해는 큰 비용과 시간을 소모하게 한다. 생물학적 피해를 예방하기 위해 목재 보존제를 처리하는 방식을 선택하여 사용한다. 목재 보존제를 선별하여 최악의 환경조건인 온도는 60±3℃, 습도는 55±5%, 광량은 0.35 W/m²로 열화 처리를 하여 화학적 변화를 분석하였다. 열화 과정을 통해 색차변화에서는 Control 군에 비하여 목재 보존제 처리에서 그 변화량이 감소하는 것을 확인하였다. 목재 보존제의 열화 과정에서 함유된 유효성분 함량을 측정한 결과에서도 비교 대상인 Wood Keeper A에 비해 Gori22와 Bondex Preserve III가 유효성분 함량이 높은 것을 확인하였다. 실험을 통해 목재 보존제가 열화 과정에서 목재 시편의 변화에 영향을 주는 정도와 유효성분의 함량을 측정하여 유효 기간 및 처리 기간을 예측할 수 있다. 추후 다양한 목재 보존제를 갖추어 선택적으로 환경이나 지형 및 기간에 맞추어 목재 보존제를 선정하는 데 주요 평가 요인이 될 가능성을 제시하였다.

• 한국ITS학회 논문지
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• 제21권5호
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• pp.103-116
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• 2022

국토교통부는 원활한 자율주행자동차 서비스 확대를 위해 총 7개 지역을 자율주행자동차 시범운행지구로 지정·고시하여 매년 운영성과에 대한 평가를 받도록 하였다. 본 연구는 이를 위한 기초연구로서 자율주행자동차 서비스의 정성적 만족도를 설문조사 기반으로 평가하였다. 첫째, 세종시 자율주행 서비스 이용자와 일반인을 대상으로 자율주행 서비스 인식에 대한 설문조사를 실시하였다. 그 결과, 자율주행 서비스 이용자가 자율주행 기술에 대한 단계 인지, 이용 의향 등이 일반인에 비해 높게 나타났다. 둘째, 수요대응형 대중교통 서비스 이용자와 세종시 자율주행 서비스 이용자를 대상으로 서비스 만족도 설문조사를 실시하였다. 비모수통계분석 방법 중 윌콕슨 순위합 검정(Wilcoxon Rank Sum Test)을 통한 분석 결과, 자율주행 서비스 이용자의 경우 안전과 관련된 요인들이 전반적인 만족도에 영향을 미치는 것으로 나타났다. 반면, 수요대응형 대중교통 서비스 이용자들은 서비스 편의성과 관련된 항목들이 전반적인 만족도에 영향을 미치는 것으로 나타났다. 이러한 설문조사 결과는 향후 자율주행 서비스의 개선사항 및 정책수립에 대한 기초자료로 활용이 기대된다.

• 대한물리치료과학회지
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• 제30권1호
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• pp.10-22
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• 2023

Background: The purpose of this study was to investigate the effect of brain education-based exercise and KPEM manual therapy integrated program on the sleep and quality of life of cancer patients. Design: Seventy subjects who were diagnosed with cancer and were undergoing treatment volunteered to participate in this study. All subjects used a nonequivalent control group pretest-posttest design for either the experimental group or the control group. In the final analysis, there were 25 subjects in the experimental group and 18 subjects in the control group. Methods: For 12 weeks, the experimental group performed brain education-based exercise (20 minutes) and KPEM manual therapy (50 minutes), and the control group performed basic physical therapy and autonomous exercise. For evaluation, the Korean version of the Pittsburgh Sleep Quality Index (PSQI-K) and the quality of life index were measured after intervention using the European Organization for Research and Treatment of Cancer (EORTC-3.0Ver). Effect between groups, time effect over time, and group^*time interaction were analyzed through a pre-test before and after the 12-week intervention period, and repeated measure ANOVA after 12 weeks of the integrated program intervention. All statistical significance levels were set at α=.05. Results: The PSQI in the time effect (p=.001) and the group^*time interaction (p<.001) were statistically significant. In terms of EORTC, QL2 and PF2 were significant in time effect (p=.024; p=.021) and group^*time interaction (p=.007; p=.021), whereas in RF2, significance was only found in group^*time interaction (p=.028). In symptom indicators, time effect was the only significant factor in FA, SL, AP, and CO, respectively (p=.002; p=.028; p=.041; p =.005) and in DY, there were significant differences in the time effect (p=.016) and group^*time interaction (p=.002). Conclusion: The brain education-based exercise and KPEM manual therapy integrated program effectively improves the sleep and quality of life of cancer patients. It is considered that this exercise and therapy can be actively used as a psychological, emotional, and physically complementary physical therapy intervention to improve the quality of life of cancer patients.

• 생명과학회지
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• 제33권5호
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• pp.397-405
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• 2023

항산화제로서 산화적 손상의 방지에 중요한 역할을 하는 것으로 알려진 glutathione (GSH)의 면역 조절에 대한 연구는 현재까지 제대로 이루어지지 않았다. 본 연구에서 우리는 환원형 GSH인 luthione^®이 RAW 264.7 세포에서 면역 강화 효과가 있는지를 조사하였다. 유세포 분석 및 면역 형광 실험의 결과에 의하면, luthione은 대조군 세포에 비해 대식세포의 대표적인 기능인 식세포 활성을 luthione 처리 농도 의적으로 증가시키는 것으로 나타났다. 또한, cytokine array의 결과에 의하면, IL-5, IL-1β와 IL-27의 발현이 luthione이 처리된 세포에서 유의하게 증가하였다. 아울러 luthione에 의한 TNF-α 및 IL-1β의 생성 증가는 그들의 단백질 발현 증가를 통해 이루어졌으며, NO 및 PGE₂와 같은 면역 매개체 유리의 증가는 iNOS 및 COX-2의 발현 증가와 관련이 있었으며, 이는 M1 대식세포 분화 마커인 CD86 발현의 증가와 연관성이 있었다. 그리고 heatmap 분석을 통하여 SOCS1/3 매개 STAT/JAK 신호 전달 경로가 luthione에 의한 면역 조절 증가에 관여함을 확인하였다. 결론적으로, 우리의 결과는 luthione이 M1 macrophage polarization의 분자 조절자로 작용하여 면역 능력을 향상시킬 수 있음을 시사한다.

• 대한족부족관절학회지
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• 제27권2호
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• pp.49-54
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• 2023

Purpose: The present study examined the effectiveness of the preoperative ischemia-modified albumin (IMA) levels in predicting the healing period of amputation wounds in patients with diabetes mellitus following a non-traumatic below-knee amputation (BKA). Materials and Methods: This study enrolled 41 diabetic foot ulcer patients who underwent BKA at the authors' hospital diabetic foot center from April 2016 to April 2022. Among the 41 patients, 29 (70.7%) were male and 12 (29.3%) were female. Their mean age was 64.54±11.38 years (41~81 years). The mean follow-up period was 19.48±5.56 weeks (14~48 weeks) after BKA. The patients were divided into two groups (high IMA group and normal IMA group), which evaluated the healing period, wound dehiscence, and revision operation rate using a Fisher's exact test and Mann-Whitney U test. Three orthopedic surgeons performed stump wound evaluation, and they were evaluated as healing when all sutures were fused without oozing. Results: Thirty patients (73.2%) (group A) showed a high level of IMA (median: 91.2 U/mL), and 11 (26.8%) patients (group B) showed a normal range of IMA (median: 82.7 U/mL). In group A, the median period for wound healing took 1.4 weeks longer, which was significant (p=0.001). No statistical relationship was observed between wound dehiscence, revision operation rate, and IMA value. There was no correlation between the other risk factors (estimated glomerular filtration rate, HbA1c) and the wound healing period. Conclusion: Although there was a limitation in using IMA as the sole factor to predict the healing period of amputation wounds in patients after BKA, this study revealed a significant positive correlation between IMA and the period of stump healing after BKA. Therefore, the preoperative IMA levels may help predict the period of stump healing after BKA.

• 동의신경정신과학회지
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• 제34권3호
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• pp.125-139
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• 2023

Objectives: This was a preliminary study to re-verify the reliability and validity of the Core Seven Emotions Inventory-Short Form (CSEI-s) and to establish standards for an objective scoring system such as T-scores and percentile for the normative group. Methods: Subjects were sampled through population-proportional regional allocation based on adults aged 20 or older and 65 or younger who voluntarily consented. Reliability was analyzed by performing an internal consistency (Cronbach's α) test and calculating means and standard deviations for each scale. The validity was analyzed between the CSEI-s and STAXI-K, SADS, COMOSWB, HADS, K-PANAS, Core emotions VAS. Results: The CSEI-s revealed notable gender discrepancies in aspects such as thought (思), fear (恐), and fright (驚), with women generally scoring higher than men. CSEI-s scores showed statistically significant differences in joy (喜) and thought (思) between those in their 20s and those in their 50s and 60s. As a result of the validity analysis, the seven-factor configuration was found to be statistically valid, and as a result of the correlation analysis with the coexistence scale, the correlation between each emotion and the seven emotions was found to be statistically significant. Cronbach's α for the CSEI-s was .891, showing statistically significant reliability. Conclusions: A preliminary study was conducted to standardize the shortened form of the Core Emotion Scale, and the reliability and validity were confirmed. A main survey of more people should be conducted in the future. Future results can contribute to revitalizing the development of oriental medicine evaluation tools and establishing an evidence base by standardizing the CSEI-s.