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A Secure Ubiquitous Storage System for Mobile Devices (모바일 기기를 위한 안전한 유비쿼터스 스토리지 시스템)

  • They, Yu-Shu;Lee, Ern-Yu;Lee, Hoon-Jae;Lim, Hyo-Taek
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.2
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    • pp.269-275
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    • 2008
  • The rapid growth of ubiquitous technology has increased the demand of storage capacity in mobile computing. iSCSI(Internet Small Computer Interface), a virtual storage protocol would be one of the possible solutions to resolve this problem. However, the insecure nature of this protocol makes it vulnerable to malicious attacks. In this paper, we aims to design and propose a new secure lightweight iSCSI-based virtual storage scheme for mobile devices. Suitable security mechanisms are considered in the design of our proposed solution in order to overcome existing security problems in iSCSI. Relevant experiments are tarried out and the results revealed that the efficiency of proposed algorithm in which it introduces over 100% Read/Write performance improvement compared with the IPsec approach.

Ant Colony Optimization and Data Centric Routing Approach for Sensor Networks

  • Lim, Shu-Yun;Lee, Ern-Yu;Park, Su-Hyun;Lee, Hoon-Jae
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.11 no.2
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    • pp.410-415
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    • 2007
  • Recent advances in sensor network technology have open up challenges for its effective routing. Routing protocol receives most of the attention because routing protocols might differ depending on the application and network architecture. In the rapidly changing environment and dynamic nature of network formation efficient routing and energy consumption are very crucial. Sensor networks differ from the traditional networks in terms of energy consumption. Thus, data-centric technologies should be used to perform routing to yield an energy-efficient dissemination. By exploiting the advantages of both ant colony optimization techniques in network routing and the ability of data centric muting to organize data for delivery, our approach will cover features for building an efficient autonomous sensor network.

Physical Activity and Quality of Life of Cancer Survivors: A Lack of Focus for Lifestyle Redesign

  • Lee, Jia Ern;Loh, Siew Yim
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.4
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    • pp.2551-2555
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    • 2013
  • Background: Physical activity is a component of lifestyle activity and one that has been increasingly seen as 'the medicine' to cure chronic diseases, including certain types of cancer. Physical activity has potent impact on mortality but only if it is well incorporated as lifestyle activity may it allow a better outcome of the quality of life of cancer survivors. This paper presents a review on the evidence of physical activity being actively promoted as lifestyle activity amongst cancer survivors, for the last five years. Materials and Methods: Electronic databases were systematically searched for randomized controlled trials incorporated as lifestyle activity through MEDLINE with the associated terms "physical activity or exercise", "quality of life" and "cancer survivor or people with cancer", 'lifestyle' and 'randomised controlled trial'. The period of search was confined to publication within January 2008 till December 2012 and further limits were to full text, peer reviewed, abstract available and English language. Results: Based on inclusion criteria, 45 articles were retrieved. Of these, 41 were excluded after examining the full paper. Four final articles on randomized controlled trials were studied to determine the effectiveness of PA to improve the quality of life in post treatment cancer survivors and positive associations were found. Conclusions: Physical activity is related to better quality of life of cancer survivors. Only one paper had characteristics of lifestyle incorporation for a lifestyle redesign, but none overtly or actively promoting exercise interventions as an essential lifestyle activity. With increasing survivorship, the benefits of physical activity must be aggressively and overtly promoted to optimize its positive impact.

Role and its Spatial utilization as a Government office of the Nambyeol-gung(南別宮) after the Japanese invasion of Korea in 1592 (임진왜란(壬辰倭亂) 이후 남별궁(南別宮)의 공해적(公廨的) 역할과 그 공간 활용) - 장서각 소장 "소공동홍고양가도형"."사대부가배치도형"의 분석을 통하여 -)

  • Chung, Jung-Nam
    • Journal of architectural history
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    • v.18 no.4
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    • pp.43-62
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    • 2009
  • No.87 Sogong-dong where is the Chosun hotel stand. There was the Nambeol-gung(south ern royal villa) which had been a reception hall for enboys of the toadied country before Hwangudan圜丘壇 being set up in the year 1897. The site of the Nambeol-gung was Gyeongjeong慶貞 princess's a lot for house in the early 15th century. But after princess's death, it occurred property dispute between her son and four daughters. As a result of the dispute, a lot and a house of all the princess's properties reverted to the government. At reverted this lot was established a big royal villa in the year 1583 and that royal villa was granted to Uian prince. The villa reverted to the government again when the Uian義安 prince was dead in 12 years old by an epidemic. After the Imjin Invasion壬辰倭亂, another houses and buildings got to be role as a palace because of all the palace in the capital was burnt down to ashes. Among others Nambeol-gung was brought into play as the royal audience chamber. As well as, the villa became brought out role as a reception hall for enboys of the toadied country instead of a damaged reception hall the Taepyong-gwan太平館. In period when the envoy didn't come, the Nambeol-gung was used to extraordinary office of government like Dogam都監. This situation is to mean that the Nambeol-gung is not the royal villa any more. Because of the Nambeol-gung was built as a royal villa, that spaces were composited like space of house and palace. But this spatial composition and spatial name were not fit to hold a ceremony of government office. After all, Nambeol-gung was used change only the spatial name conform to ceremony of office keep up the spatial composition.

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Characterization of Synechocystic PCC6803 transformed with cryIVD gene of Bacillus thuringiensis subsp. morrisoni PG-14 and its mosquitochidal effect on Anopheles sinensis (Bacillus thuringiensis subsp. morrisoni PG-14 cryIVD 유전자로 형질전환된 Synechocytis PCC6803의 특성과 학질모기에 대한 살충효과)

  • 이대원;박현우;김호산;진병래;유효석;김근영;강석권
    • Korean journal of applied entomology
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    • v.35 no.1
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    • pp.66-73
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    • 1996
  • For the effective control of mosquito larvae, Anopheles sinensis, the expression vector pCYASK5-1 containing cryIVD gene of Bacillus thuringiensis subsp. morrisoni PG-14 was constructed and transformed into the cyanobacterium Synechocystis PCC6803. The transformants were selected on BG-11 medium containing kanamycin. The expression of cryIVD gene in transformant was confirmed by SDS-PAGE and Western blot analysis. The mortality of A. sinensis larvae was scored for 3 days. Furthermore, growth and distribution rate of transformant were examined. The results showed that Synechocystis PCC6803 transformed with cryIVD gene of B. thuringiensis subsp. morrisoni PG-14 was highly toxic to A. sinensis larvae, demonstrating that it will be a potential agent for mosquito control.

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A study on the formativeness of the junk Art represented in the second half 20th century fashion (20세지 후반의 현대 패션에 나타난 정크아트(Junk Ark)의 조형성에 관한연구)

  • 이효진
    • Journal of the Korean Society of Costume
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    • v.33
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    • pp.5-25
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    • 1997
  • The purpose of this study was to analyze the characteristics of the Junk Art represented in the second half 20the century fashion. The highly developed material civilization resulted in human alienations environmental distruption. By this fact human being of the 20the century was to overcome social com-plexity. In this respect this research was focused that how the characteristics of the junk Art was expressed in the second half 20th century fashion. The concepts of the Junk Art lied in the creation of art work in the 2-dimentional plane of 3-dimentional space through the application of all junks (wood pieces industrial debris trash ready-made goods etc) cast by the mod-ern industrial society and the mass production system. Juck Art had been further envigorated in the footstep of the development of the collage method based on the creation of object aes-thetics. And junk artists have untitled social environments with art by assembling junks as a way of exploring the material world of cur-rent society and provided infinite possibilities of expressional medium and technique. Above all junk Art has been reflected in the fashion as well as other art. Especially a lot of the fashion design by the use of junks and the expressive image of junks is produced in the 20th century. That is many of fashion designers have always been aware of what is happening in the arts and have always been able to use the dis-coveries and ideas of the artist to help them solve design problems and creat fashion which are new inventive and reflective of their time. The fashion designers of the junk fashion design could be said to have presented much more possibilities and new development for-mulas to modern fashion design and provided a new order of other formative arts. Unlike the negative and destructive punk cyberpunk fashion junk fashion was a positive and optimistic aesthetics. junk fashion that keeps pace with science and the development of technology is devoted to trying to grasp the real form of ultimate re-ality.

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A whole genomic scan to detect selection signatures between Berkshire and Korean native pig breeds

  • Edea, Zewdu;Kim, Kwan-Suk
    • Journal of Animal Science and Technology
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    • v.56 no.7
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    • pp.23.1-23.7
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    • 2014
  • Background: Scanning of the genome for selection signatures between breeds may play important role in understanding the underlie causes for observable phenotypic variations. The discovery of high density single nucleotide polymorphisms (SNPs) provide a useful starting point to perform genome-wide scan in pig populations in order to identify loci/candidate genes underlie phenotypic variation in pig breeds and facilitate genetic improvement programs. However, prior to this study genomic region under selection in commercially selected Berkshire and Korean native pig breeds has never been detected using high density SNP markers. To this end, we have genotyped 45 animals using Porcine SNP60 chip to detect selection signatures in the genome of the two breeds by using the $F_{ST}$ approach. Results: In the comparison of Berkshire and KNP breeds using the FDIST approach, a total of 1108 outlier loci (3.48%) were significantly different from zero at 99% confidence level with 870 of the outlier SNPs displaying high level of genetic differentiation ($F_{ST}{\geq}0.490$). The identified candidate genes were involved in a wide array of biological processes and molecular functions. Results revealed that 19 candidate genes were enriched in phosphate metabolism (GO: 0006796; ADCK1, ACYP1, CAMK2D, CDK13, CDK13, ERN1, GALK2, INPP1; MAK, MAP2K5, MAP3K1, MAPK14, P14KB, PIK3C3, PRKC1, PTPRK, RNASEL, THBS1, BRAF, VRK1). We have identified a set of candidate genes under selection and have known to be involved in growth, size and pork quality (CART, AGL, CF7L2, MAP2K5, DLK1, GLI3, CA3 and MC3R), ear morphology and size (HMGA2 and SOX5) stress response (ATF2, MSRB3, TMTC3 and SCAF8) and immune response (HCST and RYR1). Conclusions: Some of the genes may be used to facilitate genetic improvement programs. Our results also provide insights for better understanding of the process and influence of breed development on the pattern of genetic variations.

Mutational Analysis Elucidates the Role of Conserved 237 Arginine in 23S rRNA Methylation, Which is in the Concave Cleft Region of ErmSF (ErmSF에서 두 도메인 사이에 존재하는 잘 보존된 237번 아르지닌 잔기의 위치 지정 치환 변이의 효소 활성 검색을 통한 역할 규명)

  • Jin, Hyung Jong
    • Korean Journal of Microbiology
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    • v.49 no.2
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    • pp.105-111
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    • 2013
  • The Erm family of adenine-$N^6$ methyltransferases (MTases) is responsible for the development of resistance to macrolide-lincosamide-streptogramin B antibiotics through the methylation of 23S ribosomal RNA. Recently, it has been proposed that well conserved amino acids in ErnC' located in concave cleft between N-terminal 'catalytic' domain and C-terminal 'RNA-binding' domain interacts with substrate RNA. We carried out the site-directed mutagenesis and studied the function of the ErmSF R237 mutant in vitro and in vivo. R237 amino acid residue is located in the concave cleft between two domains. Furthermore this residue is very highly conserved in almost all the Erm family. Purified mutant protein exhibited only 51% enzyme activity compared to wild-type. Escherichia coli with R237A mutant protein compared to the wild-type protein expressing E. coli did not show any difference in its MIC (minimal inhibitory concentration) suggesting that even with lowered enzyme activity, mutant protein was able to efficiently methylate 23S rRNA to confer the resistance on E. coli expressing this protein. But this observation strongly suggests that R237 of ErmSF probably interacts with substrate RNA affecting enzyme activity significantly.

Effect of Retinoids on Human Breast Cancer Cells (인체 유방암 세포에서 retinoids의 영향에 대한 연구)

  • 윤현정;신윤용;공구
    • Environmental Mutagens and Carcinogens
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    • v.24 no.2
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    • pp.51-66
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    • 2004
  • Retinoids, better known as vitamin A, have been reported to inhibit the growth of several breast cancer cell lines in culture and to reduce breast tumor growth in animal models. Furthermore, retinoids can augment the action of other breast cancer cell growth inhibitors both in vitro and in vivo. Clinically, interest has increased in the potential use of retinoids for the prevention and treatment of human breast cancer. We have examine the effect of all-trans retinoic acid(tRA) and 9-cis retinoic acid(9-cis RA) on human breast cancer cell(MCF-10A, T47-D, MCF-7) proliferation using MTT assay and cell cycle analysis(FACS). Overexpression of cyclin D1 protein is observed in the majority of breast cancers, suggesting that dysregulated expression of cyclin D1 might be a critical event in breast cancer carcinogenesis. We investigated whether tRA and 9-cis RA might affect expression of cyclin D1 on human breast cancer cells(MCF-10A, T47-D, MCF-7) using RT-PCR and west-ern bolt. In MCF-10A cells, either tRA or 9-cis RA treatment did not affect the cell proliferation. In T47-D cells and MCF-7 cells, either tRA or 9-cis RA treatment showed the inhibition of the cell proliferation over control cells and also inhibit the estrogen stimulated cell proliferation when it was given together with estrogen. The effect of retinoids was dose- and time- dependent. T47-D cells treated with 1.0 $\muM$ tRA undergo G0/G1-phase arrest by Day 5. MCF-7 cells treated with 1.0 $\muM$ tRA undergo S-phase arrest by Day 5. All-trans retinoic acid(tRA) and 9-cis retinoic acid(9-cis RA) inhibited the cyelin D1 mRNA and protein expression levels of human MCF-7 and T47-D breast carcinoma cells in vitro. The data indicate that retinoids can reduce cyclin D1 expression levels in a variety of breast cell lines in vitro and result in inhibition of cell proliferation. tRA-mediated growth inhibition and cyclin D1 expression inhibition is more potent than 9-cis RA mediated that. tRA-mediated inhibition effect is more potent on T47-D cells than on MCF-7 cells. Our data suggest that retinoids activity is different according to property of cell lines. Future chemoprevention of breast cancer studies using retinoids will be necessary to determine the mechanism of the retinoids-mediated growth inhibition.

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Collision Strength Assessment for Double Hull Type Product Carrier Using Finite Element Analysis (이중 선체 화학 운반선의 충돌 강도 평가)

  • Paik, Jeom-Kee;Lee, Jae-Myung;Lee, Kyung-Ern;Won, Suk-Hee;Kim, Chelo-Hong;Ko, Jae-Yong
    • Journal of Navigation and Port Research
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    • v.28 no.6
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    • pp.481-489
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    • 2004
  • Ship collisions and grounding continue to occur regardless of continuous efforts to prevent such accidents. With the increasing demand for safety at sea and for protection of the environment, it is of crucial importance to be able to reduce the probability of accidents, assess their consequences and ultimately minimize or prevent potential damages to the ships and the marine environment. Numerical simulations for actual collision problem are conducted with a special attention with respect to finite element size, fracture criteria and material properties, which require a careful consideration to improve the accuracy. A parametric analysis varying colliding speed, angle, design loading condition is conducted using nonlinear finite element analysis method for 46,00 dwt Product/chemical carrier. The relationship between the absorbed energy and indentation are derived quantitatively using the insights observed from this study, and a novel design concept for assessing the anti-collision performance are proposed.