• Progress in Medical Physics
• /
• v.24 no.4
• /
• pp.253-258
• /
• 2013

The purpose of this study is to evaluate and analyze the relationship between the external radiation dose reconstruction which is transmitted from the patient who receives radiation treatment through electronic portal imaging device (EPID) and the internal dose derived from the Monte Carlo simulation. As a comparative analysis of the two cases, it is performed to provide a basic indicator for similar studies. The geometric information of the experiment and that of the radiation source were entered into Monte Carlo n-particle (MCNPX) which is the computer simulation tool and to derive the EPID images, a tally card in MCNPX was used for visualizing and the imaging of the dose information. We set to source to surface distance (SSD) 100 cm for internal measurement and EPID. And the water phantom was set to be 100 cm of the source to surface distance (SSD) for the internal measurement and EPID was set to 90 cm of SSD which is 10 cm below. The internal dose was collected from the water phantom by using mesh tally function in MCNPX, accumulated dose data was acquired by four-portal beam exposures. At the same time, after getting the dose which had been passed through water phantom, dose reconstruction was performed using back-projection method. In order to analyze about two cases, we compared the penetrated dose by calibration of itself with the absorbed one. We also evaluated the reconstructed dose using EPID and partially accumulated (overlapped) dose in water phantom by four-portal beam exposures. The sum dose data of two cases were calculated as each 3.4580 MeV/g (absorbed dose in water) and 3.4354 MeV/g (EPID reconstruction). The result of sum dose match from two cases shows good agreement with 0.6536% dose error.

• Progress in Medical Physics
• /
• v.25 no.3
• /
• pp.139-142
• /
• 2014

The purpose of this study was to develop a system of clinical application of reconstructed dose that includes dose reconstruction, reconstructed dose registration between fractions of treatment, and dose-volume-histogram generation and to demonstrate the system on a deformable prostate phantom. To achieve this purpose, a deformable prostate phantom was embedded into a 20 cm-deep and 40 cm-wide water phantom. The phantom was CT scanned and the anatomical models of prostate, seminal vesicles, and rectum were contoured. A coplanar 4-field intensity modulated radiation therapy (IMRT) plan was used for this study. Organ deformation was simulated by inserting a "transrectal" balloon containing 20 ml of water. A new CT scan was obtained and the deformed structures were contoured. Dose responses in phantoms and electronic portal imaging device (EPID) were calculated by using the XVMC Monte Carlo code. The IMRT plan was delivered to the two phantoms and integrated EPID images were respectively acquired. Dose reconstruction was performed on these images using the calculated responses. The deformed phantom was registered to the original phantom using an in-house developed software based on the Demons algorithm. The transfer matrix for each voxel was obtained and used to correlate the two sets of the reconstructed dose to generate a cumulative reconstructed dose on the original phantom. Forwardly calculated planning dose in the original phantom was compared to the cumulative reconstructed dose from EPID in the original phantom. The prescribed 200 cGy isodose lines showed little difference with respect to the "prostate" and "seminal vesicles", but appreciable difference (3%) was observed at the dose level greater than 210 cGy. In the rectum, the reconstructed dose showed lower volume coverage by a few percent than the plan dose in the dose range of 150 to 200 cGy. Through this study, the system of clinical application of reconstructed dose was successfully developed and demonstrated. The organ deformation simulated in this study resulted in small but observable dose changes in the target and critical structure.

• Progress in Medical Physics
• /
• v.11 no.2
• /
• pp.91-99
• /
• 2000

This is a preliminary study for developing the method of the dose reconstruction in the patients, irradiated by mega-voltage photon beams from the linear accelerator, using the transit dose distributions. In this study we present the method of three-dimensional dose reconstruction and evaluate the method by computer simulation. To acquire the dose distributions in the patients (or phantoms) we first calculate the differences between the doses at the arbitrary points in the patients and the doses at the corresponding points where the transit doses are measured. Then, we can get the dose in the patients from the measured transit dose and the calculated value of the difference. The dose differences are calculated by applying the inverse square law and using the linear attenuation coefficient. The scatter to primary dose ratios, which are calculated by the Monte Carlo program using the CT data of the patient (or phantoms), are also used in the calculations. For the evaluation of this method we used various kinds of homogeneous and inhomogeneous phantoms and calculated the transit dose distributions with the Monte Carlo program. From the distributions we reconstructed the dose distributions in the phantom. We used mono-energy Photon beam of 1.5MeV and Monte Carlo program EGS4. The comparison between the dose distributions reconstructed using the method and the distributions calculated by the Monte Carlo program was done. They agreed within errors of -4%∼+2%. This method can be used to predict the dose distributions in the patient