• Title/Summary/Keyword: EP2

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Sensitivity of Whole-Blood Interferon-Gamma Release Assay According to the Severity and the Location of Disease in Patients with Active Tuberculosis (활동성 결핵의 중증도 및 병변 부위에 따른 전혈 인터페론 감마 분비능 측정의 민감도)

  • Kim, Yi-Young;Lee, Jae-Hee;Lee, Yoon-Jee;Lee, So-Yeon;Lee, Yong-Hun;Choi, Keum-Ju;HwangBo, Yup;Cha, Seung-Ick;Park, Jae-Yong;Jung, Tae-Hoon;Park, Jun-Sik;Kim, Chang-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.70 no.2
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    • pp.125-131
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    • 2011
  • Background: The clinical manifestation of $M.$ $tuberculosis$ infection ranges from asymptomatic latent infection, to focal forms with minimal symptoms and low bacterial burdens, and finally to advanced tuberculosis (TB) with severe symptoms and high bacillary loads. We investigated the diagnostic sensitivity of the whole-blood interferon-${\gamma}$ release assay according to the wide spectrum of clinical phenotypes. Methods: In patients diagnosed with active TB that underwent $QuantiFERON^{(R)}$ (QFT) testing, the QFT results were compared with patients known to be infected with pulmonary tuberculosis (P-TB) and extra-pulmonary TB (EP-TB). In addition, the results of the QFT test were further analyzed according to the radiographic extent of disease in patients with P-TB and the location of disease in patients with EP-TB. Results: There were no statistical differences in the overall distribution of QFT results between 177 patients with P-TB and 84 patients with EP-TB; the positive results of QFT test in patients with P-TB and EP-TB were 70.1% and 64.3%, respectively. Among patients with P-TB, patients with mild extents of disease showed higher frequency of positive results of QFT test than that of patients with severe form (75.2% vs. 57.1%, respectively; p=0.043) mainly due to an increase of indeterminate results in severe P-TB. Patients with TB pleurisy showed lower sensitivity by the QFT test than those with tuberculous lymphadenitis (48.8% vs. 78.8%, respectively; p=0.019). Conclusion: Although QFT test showed similar results between overall patients with P-TB and EP-TB, individual sensitivity was different according to the radiographic extent of disease in P-TB and the location of disease in EP-TB.

Study on Simultaneous Analysis and Use of Preservatives in Mouthwashes (구강 청정제 중 보존제의 동시 분석법 확립과 사용실태에 관한 연구)

  • Jung, Sang-Mi;Moon, Tae-Jung;Kim, Jae-Dong;Lee, Gye-Won
    • Journal of Digital Convergence
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    • v.10 no.6
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    • pp.331-339
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    • 2012
  • The easy and simple simultaneous analytical method of preservatives (BA, SA, DHA, MP, EP, IPP, PP, IBP and BP) was studied by more easily changing from method used in food and drug using HPLC with scherzo SM-C18 column. All presevatives were seperated successfully in mobile phase of 50 mM ammonium formate : 0.1% phosphoric acid (50:50 v/v%) and 50 mM ammonium formate : acetonitrile (30 : 70). Retention time of BA, SA, DHA, MP, EP, IPP, PP, IBP and BP was 7.74, 9.08, 12.57, 13.83, 21.62, 27.29, 28.20, 33.20 and 33.68 min, respectively. The calibration curves of BA, SA, DHA, MP, EP, IPP, PP, IBP and BP were linear over the concentration range of 5~80 ${\mu}g/mL$ with correlation coefficient of above 0.999. The limit of detection (LOD) and limit of quantitation (LOQ) of BA, SA, DHA, MP, EP, IPP, PP, IBP and BP were 0.52 and 1.58, 1.09 and 3.29, 1.00 and 3.03, 1.36 and 4.13, 1.26 and 3.83, 1.02 and 3.08, 1.11 and 3.37, 0.82 and 2.48, 0.85 and 2.59 ${\mu}g/mL$, respectively. The coefficients of variation for intra- and inter-day assay were 0.12~2.68 and 0.18~2.66%, respectively. The developed method showed good intra- and inter-day precision and accuracy. The preservatives used in mouthwashes were BA, MP and PP and were detected in 24 samples(86%) except for 4 samples and not showed significant difference in using dose of adult and children. In conclusion, the developed method can be useful for simultaneous analysis of preservatives in mouthwashes and these results suggest that could be applied to fundamental study and guideline on content of preservatives in mouthwashes.

Monitoring of Low-velocity Impact Damage Initiation of Gr/Ep Panel 7sing Piezoeleetric Thin Film Sensor (압전필름센서를 이용한 복합재 평판의 저속충격 손상개시 모니터링)

  • 박찬익;김인걸;이영신
    • Composites Research
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    • v.15 no.2
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    • pp.11-17
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    • 2002
  • The piezoelectric thin film sensor can be used to interpret variations in structural and material properties, e.g. for structural integrity monitoring and assessment. To illustrate one of this potential benefit, PVDF (polyvinylidene fluoride) film sensors are used for monitoring impact damage in Gr/Ep composite panels. Both PVDF film sensors and strain gages are attached to the surface of Gr/Ep specimens. A series of impact tests at various impact energy by changing impact mass the height are performed on the instrumented drop weight impact tester. The sensor responses are carefully examined to predict the onset of impact damage such as indentation, matrix cracking, and delamination, etc. Test results show that the particular waveforms of sensor signals implying the damage initiation and development are detected above the damage initiation impact energy. As expected, the PVDF film sensor is found to be more sensitive to impact damage initiation event than the strain gage.

Effect of Surface Free Energies on Mechanical Properties of Epoxy/Polyurethane Blend System (에폭시/폴리우레탄 블렌드 시스템의 표면 자유에너지 변화가 기계적 특성에 미치는 영향)

  • 박수진;진중성;이재락;박병기
    • Polymer(Korea)
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    • v.24 no.2
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    • pp.245-251
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    • 2000
  • A blend system prepared from epoxy(EP) and polyurethane (PU) was investigated in terms of the contact angle and mechanical properties. The contents of EP/PU were varied within 100/0~100/60 phr in the presence of 20 phr DDM (4,4'-diamino diphenyl methane) as a curing agent for epoxy resin. Contact angle measurements were performed employing a Rame-Hart contact angle goniometer. Deionized water and diiodomethane were chosen as the testing liquids. In this work, Owens-Wendt and Wu's models using a geometric mean were studied to analyze the surface free energy of blend system. For the mechanical and toughening properties of the casting specimens, the critical stress Intensity factor ($K_{IC}$) and impact test were performed. Especially, the impact test was carried out at room and cryogenic temperatures. As a result, specific or polar component of the surface free energy of the blend system was largely influenced on the addition of the PU resulting in increasing the impact strength for the excellent low- temperature performance.

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An Economic Feasibility Comparison of the extruded pellets and moist pellet on the Oliver flounder Culture Farms (넙치 배합사료 및 생사료의 경제성 비교분석)

  • Hwang, Jin-Wook;Kim, Do-Hoon
    • The Journal of Fisheries Business Administration
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    • v.40 no.3
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    • pp.189-205
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    • 2009
  • This study is aimed to analyze the economic feasibility comparison of the extruded pellets and moist pellets on the Oliver flounder culture farms in Jeju Island. In order to do this, we selected 2 farms (M and S farms) in Jeju Island as a sample. In the study, various analyses including productivity analysis, cost structure analysis, profitability and economic feasibility analysis by feed type were conducted for two sample farms of Oliver flounder culture. The results of economic analysis by feed type on the Oliver flounder culture can be summarized as follows; First, there were not significant differences in productivity by feed type. Second, results of the profitability analysis on farm M by feed type showed the profitability was estimated to be 15.52% and 9.83% in EP and MP, respectively. In addition, the profitability of farm S was estimated to be 28.37% and 33.72% in EP and MP, respectively. Third, results of the economic analysis on farm M by feed type indicated that an internal rate of return(IRR) was 8% and 7% and a benefit-cost ratio was shown to be 1.64 and 1.11 in EP and MP, respectively. Furthermore, the economic analysis of farm M by feed type showed that an IRR was 19% and 24% and a benefit-cost ratio was calculated to be 1.4 and 1.51 in EP and MP, respectively. In summary, it is especially emphasized that economic valuation is not related to feed types (EP and MP). Finally, in order to improve the economic feasibility, it should be more focused on the efficient business management of the Oliver flounder aquaculture.

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Immunostimulating Exopolysaccharide with Anticancer Activity from Enterobacter sp. SSYL[KCTC 0687BP] Screened from Ulmus parvifolia (느릅나무로부터 분리된 Enterobacter sp. SSYL[KCTC 0687P]이 생산하는 당화합물의 항암 면역활성 연구)

  • 양영렬;김영주
    • KSBB Journal
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    • v.16 no.6
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    • pp.554-561
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    • 2001
  • Immunostimulating exopolysaccharides with anticancer activity produced by Enterobacter sp. SSYL(KCTC 0687BP), isolated from Chinese elm(Ulmus sp.) were investigated. The exopolysaccharide contains molecular weight 100,000 to 1,000,000 Da and total carbohydrates 43.0 to 70.8%, total uronic acid 7.1 7o 12.4%, and total proteins 15.4 to 20.6%. Compositions and contents of sugars in the exopolysaccharides are 10-30% glucose, less than 1% fructose, 10-15% galactose, 8-12% fucose, and 40-70% glucuronic acid. The anticancer immunostimulating activities were examined and proved with regard to both in vitro and in vivo bioassays. In vivo assay, the glycoprotein at the concentration of 0.3 mg/kg showed the best result that median survival time in creased to ca. 138.1% in contrast to control groups.

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Eyeblinks, EP Augmenting / Reducing and Personality (눈깜작임, 증감뇌유발전위와 성격의 상호관계)

  • Lee, Sung-Hoon;Haier, Richard J.
    • Sleep Medicine and Psychophysiology
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    • v.1 no.2
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    • pp.156-162
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    • 1994
  • Objectives: Eyeblinking varied depending on individual cognitive abilities or personality traits thought to related to brain mechanisms of sensory modulation. This study explored whether personality traits are related to the rate of eye blinks and how eyeblink and evoked potential augumenting-reducing(EPAR) interact Methods: Forty four students were studied with EPAR topography to explore how eyeblinks, personality and EPAR interact The Zuckerman Sensation Seeking Scale(SSS) and Eysenck Personality Questionnaire(EPQ) were used as personality measured by a stimulus response program during EP study. Results: Rate of blink increased as intensity of light increased. The General(GEN), Thrill and Adventure Seeking(TAS), Experience Seeking(ES) and Disinhibition(DS) subscales in SSS and Extraversion-Introversion(E) subscale in EPQ showed significant negative correlations with number of eyeblinks in the hightest intensity of light, whereas Neuroticism(N) subscales in EPQ showed a positive correlation. Correlation between number of eyeblinks with the brightest light and EPAR slope varied topographically. The strongest positive correlation was noted in right posterior temporal area. Conclusion: High sensation seekers blinked significantly fewer times than lower sensation seeker did. Higher personality correlations with eyeblink than with EP may imply that the eyeblink works as a primary filter since it is more directly related to central mechanisms of sensory modulation than EP. The right posterior temporal area may play an important role in modulation of visual stimuli.

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A Study on Multi-Vehicle Control of Electro Active Polymer Actuator based on Embedded System using Adaptive Fuzzy Controller (Adaptive Fuzzy 제어기를 이용한 Embedded 시스템 기반의 기능성 고분자 구동체 다중제어에 관한 연구)

  • 김태형;김훈모
    • Journal of the Korean Society for Precision Engineering
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    • v.20 no.2
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    • pp.94-103
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    • 2003
  • In case of environment requiring safety such as human body and requiring flexible shape, a conventional mechanical actuator system does not satisfy requirements. Therefore, in order to solve these problems. a research of various smart material such as EAP (Electro Active Polymer), EAC (Electro Active Ceramic) and SMA (Shape Memory Alloy) is in progress. Recently, the highest preferring material among various smart material is EP (Electrostictive Polymer), because it has very fast response time, powerful force and large displacement. The previous researches have been studied properties of polymer and simple control, but present researches are studied a polymer actuator. An EP (Electostrictive Polymer) actuator has properties which change variably ils shape and environmental condition. Therefore, in order to coincide with a user's purpose, it is important not only to decide a shape of actuator and mechanical design but also to investigate a efficient controller. In this paper, we constructed the control logic with an adaptive fuzzy algorithm which depends on the physical properties of EP that has a dielectric constant depending on time. It caused for a sub-actuator to operate at the same time that a sub-actuator system operation increase with a functional improvement and control efficiency improvement in each actuator, hence it becomes very important to manage it effectively and to control the sub-system which Is operated effectively. There is a limitation on the management of Main-host system which has multiple sub-system, hence it brings out the Multi-Vehicle Control process that disperse the task efficiently. Controlling the multi-dispersion system efficiently, it needs the research of Main-host system's scheduling, data interchange between sub-actuators, data interchange between Main-host system and sub-actuator system, and data communication process. Therefore in this papers, we compared the fuzzy controller with the adaptive fuzzy controller. also, we applied the scheduling method for efficient multi-control in EP Actuator and the algorithm with interchanging data, protocol design.

Investigating Meat Quality of Broiler Chickens Fed on Heat Processed Diets Containing Corn Distillers Dried Grains with Solubles

  • Shim, YoungHo;Kim, JinSoo;Hosseindoust, Abdolreza;Choi, YoHan;Kim, MinJu;Oh, SeungMin;Ham, HyungBin;Kumar, Alip;Kim, KwangYeol;Jang, Aera;Chae, ByungJo
    • Food Science of Animal Resources
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    • v.38 no.3
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    • pp.629-635
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    • 2018
  • The present study investigated the effects of feed form and distiller's dried grain with solubles (DDGS) on meat quality and fatty acids profile of broiler chickens. A total of 720 broilers (Ross 308; average BW [body weight] $541{\pm}5.7g$) were randomly allotted to six treatments. Birds were fed three different feed forms (mash; SP, simple pellet; EP, expanded pellet) and DDGS (0 or $200g\;kg^{-1}$) in a $3{\times}2$ factorial arrangement. The addition of DDGS and EP to the diet resulted in increased shear force of breast meat. Moreover, DDGS inclusion in the diet reduced the concentration of stearic acid and behenic acid in thigh meat. Pelleting (SP and EP) of the diets increased palmitic acid content in the thigh, whereas the linolenic acid content decreased. The breast mass was higher with EP and SP diets than with the mash diet. Feed processing led to increased pectoralis muscle and drum mass compared to mash-fed chickens. In conclusion, our results demonstrated that EP decreased thigh linolenic acid and meat shear force. In addition, DDGS supplementation in broiler hampers meat quality by increasing the shear force.

Breaking the Gender Gap: A Two-part Observational Study of the Gender Disparity Among Korean Academic Emergency Physicians

  • Lee, Mi Jin;Kim, Changho
    • Journal of Preventive Medicine and Public Health
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    • v.53 no.5
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    • pp.362-370
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    • 2020
  • Objectives: Despite greater access to training positions and the presence of more women in emergency medicine, it has remained a men-dominated field. This study aims to identify the key issues causing the gender gap in Korea and establish measures to overcome them. Methods: Using the annual statistical reports of the National Emergency Medical Center and data published on the Korean Society of Emergency Medicine website, cases that listed the current status and positions of members in its organization and its committees were analyzed. Secondary analysis was conducted using data from the 2015 Korean Society of Emergency Survey that included physicians' demographics, academic ranking, years of experience, clinical work hours, training and board certification, core faculty status, position, and salaries. Results: As of September 2019, women account for only 12.7% of the total number of emergency physicians (EP) in Korea; of 119 chair/vice-chair academic positions, women represented only 9.2%. Women EP were more often assistant professors and fellowship-trained, with fewer in core faculty. However, they worked the same numbers of clinical hours as their men counterparts. The median annual salary of women EP was less than that of men EP after adjusting for academic hospital rank, clinical hours, and core faculty status. Conclusions: A gender gap still exists among Korean EP, and women earn less than men regardless of their rank, clinical hours, or training. Future studies should evaluate more data and develop system-wide practices to eliminate gender disparities.