• Title/Summary/Keyword: EO(Ethylene Oxide)

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Embryo and Fetal Developmental Toxicity Study on Gamma-Irradiated Korean Ginseng in Rats (방사선 조사 인삼이 랫드의 기형유발에 미치는 영향에 관한 연구)

  • 박귀례;신재호;김판기;이유미;장성재
    • Toxicological Research
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    • v.17 no.1
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    • pp.27-32
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    • 2001
  • Korean ginseng products have been fumigated with ethylene oxide (EO) for sterilization and prolongation of storage periods. However, there had been controversies indicating that consumption of EO treated foods might cause harmful effects in human. In Korea, the use EO gas for food treatment was banned in 1991. Since then, irradiation technique has been developed as an alternative. This study was carried out to evaluate the safety of irradiated ginseng on embryo and fetal developmental toxicity effects in rats. Either EO gas fumigated or $\gamma$-irradiated ginseng was administered to pregnant Wistar rats by oral gavage from gestational day 7 to 17. The amount of irradiation used in this study was 5, 10 and 30 kGy, respectively. There were no treatment related changes of dams in deaths, clinical signs, food consumption and body/organ weight. No treatment related changes in implantation ratio, litter size, sex ratio and body/organ weight of fetuses were observed. Also, no F1fetuses with external, visceral, head and skeletal mal-formation were observed. The results of this study showed that $\gamma$-irradiated ginseng, up to 30 kGy, has no adverse effects on fetal development of rats.

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Evaluation of Peri- and Postnatal Toxicity of Gamma-Irradiated Korean Ginseng in Rats (방사선 조사 인삼이 랫드의 태자와 신생자의 발달 및 모체기능에 미치는 영향에 관한 연구)

  • 박귀례;한순영;김판기;신재호;장성재
    • Toxicological Research
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    • v.17 no.1
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    • pp.17-25
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    • 2001
  • Korean ginseng products have been fumigated with ethylene oxide (EO) for sterilization and prolongation of storage periods. However, there had been controversies indicating that consumption of EO treated foods might cause harmful effects in human. In Korea, the use EO gas for sterilization of food was banned in 1991. Since then, irradiation technique has been developed as an alternative. This study was carried out to evaluate the safety of irradiated ginseng on peri- and postnatal developmental toxicity in rats. Either EO gas fumigated or gamma-irradiated ginseng was administered to pregnant Wistar rats by oral gavage from gestational day 16 to postnatal day 21. The amount of irradiation used in this study was 5, 10 and 30 kGy, respectively. There were no treatment related changes of dams in deaths, clinical signs, and parturition. No treatment related changes in food consumption, body/organ weight and lactation of dams were observed. Also, no F1 fetuses in external abnormality, physical development, reflex/sensory junctions and behavioral development were found. The results of this study showed that gamma-irradiated ginseng, up to 30 kGy, has no adverse effects on the peri- and postnatal development of rats.

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Recycling of the Waste Cellulose ―II. Preparation of Hydroxyethyl Cellulose from Knit-Cotton-Waste― (셀룰로오스계 폐기물의 재활용 ―II. 폐면으로부터 hydroxyethyl cellulose 제조―)

  • Lee, Sung Goo;Ihm, Sung Dam;Kim, Byung Suk;Mun, Sung Phil;Rhee, John Moon
    • Textile Coloration and Finishing
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    • v.7 no.2
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    • pp.32-39
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    • 1995
  • Various grades of hydroxyethyl cellulose (HEC, MS 0.65-3.20) were prepared throngh reaction of the knit-cotton-waste with ethylene oxide(EO). The knit-cotton-waste was composed of 98% of $\alpha$-cellulose and 2% of other components, and the cellulose was highly pure. The molar ratio of EO to knit-cotton-waste and that of NaOH to knit-cotton-waste, and the agitation speed were the important factors determining the molar substitution(MS) during the preparation of HEC. The MS of HEC was remarkably increased with increasing molar ratio of EO' to knit-cotton-waste. When the molar ratio of EO to knit-cotton-waste was 3.5, that of NaOH to knit-cotton-waste was 1.25, and agitation speed was 450rpm, it was possible to prepare HEC of MS 2.5. The structure and crystallinity of HECs prepared were determined by FT-IR and X-ray diffraction.

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Electrochemical Properties of PVdF Gel Polymer Electrolyte with Plasticizer for Lithium/sulfur Battery (리튬 유황 전지용 PVdF 겔 고분자 전해질의 가소제에 따른 전기화학적 특성 평가)

  • Ryu, Ho-Suk;Kim, Jong-Seon;Kim, Dong-Ju;Kim, Dong-Yeon;Kim, Ic-Pyo;Ahn, Hyo-Jun;Kim, Ki-Won;Ahn, Jou-Hyeon;Lee, Gun-Hwan
    • Journal of the Korean Electrochemical Society
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    • v.10 no.3
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    • pp.213-218
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    • 2007
  • In order to find out proper PVdF gel polymer electrolyte for Li/S battery, we investigated PVdF gel polymer electrolytes with various glyme type plasticizer such as polyglyme, tetraglyme, triglyme. The organic solvents as triglyme, tetraglyme, polyglyme (Mn = 250, 500) has different chain length of ethylene oxide(EO) in solvent of glyme system. ionic conductivity decreased as increasing chain length of EO in plasticizers. Ionic conductivity of PVdF gel electrolyte with tetraglyme, triglyme, polyglyme (Mn = 250, 500) at room temperature was $5{\times}10^{-4},\;3{\times}10^{-4},\;6{\times}10^{-5},\;3{\times}10^{-5}\;S/cm$, respectively. Li/S cell with PVdF gel polymer electrolyte using tetraglyme plasticizer had low interfacial resistance and the highest initial discharge capacity of 1232 mAh/g of active sulfur, which was about 70% utilization of theoretical value.

Antibacterial property of 4-hexylresorcinol incorporated in silk mat after sterilization

  • Kim, Seong-Gon;Kweon, HaeYong;Jo, You-Young
    • International Journal of Industrial Entomology and Biomaterials
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    • v.42 no.2
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    • pp.46-50
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    • 2021
  • When 4-hexylresorcinol (4HR) incorporated silk mat is used for clinical application, sterilization process is essential. In this study, 4HR incorporated silk mat was sterilized with ethylene oxide (EO) gas or autoclave, and then antibacterial property was evaluated. For the examination of micro-structure after the sterilization, scanning electron microscopic (SEM) exam and Fourier Transform Infrared (FT-IR) spectroscopy were also done. There was no gross difference after sterilization in SEM exam and FT-IR spectra. Antibacterial property of 4HR was also maintained after the sterilization. In conclusion, EO gas or autoclave did not damage the antibacterial property of 4HR in the silk mat.

Synthesis, Characterization, and Properties of Ethoxylated Azo Dyes

  • Shen, Kaihua;Choi, Dong Hoon;Li, Zongshi
    • Fibers and Polymers
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    • v.4 no.1
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    • pp.32-37
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    • 2003
  • The nonionic surfactant properties of ethoxylated azo dyes, such ai cloud point and surface tension have been investigated. The synthesized ethoxylated azo dyes could dye polyester fabric without any special pre-treatment. When the average number of ethylene oxide (EO) in the ethoxylated azo dye reached 6, its fixation could exceed $90^{\circ}C$ from the thermosol dyeing process. The average degree of condensation of ethylene glycol in the chain was interrelated with the dyeing results and did not affect on the maximum absorption wavelength (λmax) of the polyoxyethylene dye. When the average length of polyoxyethylene chain decreased, the molecular weight of dyes became smaller and the fixation of dyes was improved.

The Conductivity Properties of Poly(ethylene oxide) Polymer Electrolyte as a Function of Temperature, Kinds of Lithium Salt and Plasticizer Addition (Poly(ethylene oxide) 고분자 전해질의 온도, Li 염의 종류 및 가소제 첨가에 따른 전도도 특성)

  • Kim, J.U.;Jin, B.S.;Moon, S.I.;Gu, H.B.;Yun, M.S.
    • Proceedings of the KIEE Conference
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    • 1994.07b
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    • pp.1229-1232
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    • 1994
  • The purpose of this study is to research and develop solid polymer electrolyte(SPE) for Li secondary battery. This paper describes the effects of lithium salts, plasticizer addition and temperature dependence of conductivity of PEO electrolytes. Polyethylene oxide(PEO) based polymer electrolyte films were prepared by solution casting an acetonitrile solution of preweighed PEO and Li salt. After solvent evaporation, the electrolyte films were vacuum-dried at $60^{\circ}C$ for 48h, the thickness of the films were $90{\sim}110{\mu}m$. The conductivity properties of prepared PEO electrolytes are summarized as follows. PEO electrolyte complexed with $LiClO_4$ shows the better conductivity of the others. $PEO-LiClO_4$ electrolyte when $EO/Li^+$ ratio is 8, showed the best conductivity. Optimum operating temperature of PEO electrolyte is $60^{\circ}C$. By adding propylene carbonate and ethylene carbonate to $PEO-LiClO_4$ electrolyte, its conductivity was higher than $PEO-LiClO_4$ without those. Also $PEO_8LiClO_4$ electrolyte remains static up to 4.5V vs. $Li/Li^+$.

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Capillary Gel Electrophoretic Analysis of Cattle Breeds Based on Difference of DNA Mobility of Microsatellite Markers

  • Lee, Mi-Ji;Yoon, Du-Hak;Jeon, Jin-Tae;Eo, Seong-Kug;Kang, Seong-Ho
    • Bulletin of the Korean Chemical Society
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    • v.30 no.11
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    • pp.2655-2660
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    • 2009
  • A breed of cattle, i.e., Korean cattle (Hanwoo), was identified based on the DNA mobilities of their microsatellites (MSs) by capillary gel electrophoresis (CGE) with a laser-induced fluorescence (LIF) detector. The MS markers were used for the accurate identification of species-specific genes. The DNA mobilities of the MS markers of Hanwoo and Holstein were measured using a CGE system with a fused-silica capillary (inner diameter of 75 ${\mu}m$, outer diameter of 365 ${\mu}m$, and total length of 50 cm). The capillary was dynamically coated with 1.0% (w/v) polyvinylpyrrolidone ($M_r$ = 1,000,000) and then filled with a mixture of 1.3% (w/v) poly(ethylene oxide) ($M_r$ = 600,000) and 1.9% (w/v) poly(ethylene oxide) (Mr = 8,000,000) as a sieving gel matrix. The species-specific genes of Hanwoo and Holstein were clearly distinguished within 33 min. This CGE assay technique is expected to be a useful analytical method for the fast and accurate identification of breeds of cattle.

Inactivation of Infectious Microorganisms by Disinfection and Sterilization Processes for Human Amniotic Membrane Grafts (이식을 위한 사람 양막의 소독 및 멸균공정에 의한 감염성 위해인자 불활화 효과)

  • Bae, Jung-Eun;Kim, Chan-Kyung;Kim, In-Seop
    • Korean Journal of Microbiology
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    • v.45 no.4
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    • pp.346-353
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    • 2009
  • Viral, bacterial, and fungal infection can be transmitted from donor to recipient via transplantation of human amniotic membrane. Therefore human amniotic membrane for transplantation should be disinfected and sterilized before use. The purpose of this study was to examine the efficacy of the disinfection process and sterilization processes used at human tissue bank in the inactivation of viruses, bacteria, and fungi. A variety of experimental model viruses, bacteria, and fungus for human pathogens, including the human immunodeficiency virus type 1 (HIV-1), bovine herpes virus (BHV), bovine viral diarrhoea virus (BVDV), hepatitis A virus (HAV), porcine parvovirus (PPV), Escherichia coli, Bacillus subtilis, and Candida albicans were all selected for this study. Enveloped viruses such as HIV-1, BHV, and BVDV were effectively inactivated to undetectable levels by 70% ethanol treatment, gamma irradiation process, and ethylene oxide (EO) gas sterilization process. Also non-enveloped viruses such as HAV and PPV were effectively inactivated to undetectable levels by gamma irradiation and EO gas treatment. However HAV and PPV showed high resistance to 70% ethanol treatment. E. coli and C. albicans were effectively inactivated to undetectable levels by 70% ethanol treatment, gamma irradiation process, and EO gas treatment. Also B. subtilis was effectively inactivated to undetectable levels by gamma irradiation process and EO gas treatment. However it showed high resistance to 70% ethanol treatment.

Optimal Surfactant Structures for Cosurfactant-Free Microemulsion Systems (III) -Nonylphenol and Tridecyl Alcohol Hydrophobes- (계면활성제의 구조가 Microemulsion 형성에 미치는 영향(제 III보) -친유기 Nonylphenol과 Tridecyl alcohol-)

  • 김천희
    • Journal of the Korean Society of Clothing and Textiles
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    • v.18 no.4
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    • pp.473-479
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    • 1994
  • 보소계면활성제 없이 microemulsion을 형성하는 최적의 계면활성제 구조를 찾기 위한 일련의 연구 중 세번째로 propoxylated nonylphenol sulfates와 ethoxylated 혹은 propoxylated highly-branched tridecyl alcohol sulfates를 연구하였다. 온도, NaCl농도, 보조계면활성제 농도, ethylene oxide몰수(EON), propylene oxide몰수(PON) 등을 변인으로 하여 phase behavior 실험을 한 결과 tridecyl alcohol 친유기를 갖는 계면활성제가 보조계면활성제 없이 microemulsion을 형성하였다. $C_{13}O(EO)_mPO)_nSO_3Na$ 일반식으로부터 m과 n을 변경시킴으로써 계의 다양한 조건을 만족시키는 계면활성제를 디자인할 수 있었다.

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