• Proceedings of the Korea Information Processing Society Conference
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• 2017.11a
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• pp.1322-1325
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• 2017

최근 비콘을 이용하여 근거리에 있는 사용자를 찾아 다양한 혜택을 지원해주는 서비스가 제공되고 있다. 2016년에 Google은 보안성 강화를 위해 비콘의 고유 ID를 사용하는 것이 아닌, 주기적으로 변경되는 임시 ID를 사용하여 이를 암호화하고 Broadcasting 하는 Eddystone-EID(Ephemeral Identity)를 공개하였다. EID를 사용하기 위해서는 Google에 비콘의 정보를 등록하는 과정과 EID를 수신 후 Google을 통해 검증하는 과정이 필요하다. 이러한 이유로 외부 업체들도 EID를 사용하기 위해서는 Google에 비콘을 등록해야 하는 문제점이 발생한다. 이러한 문제점을 해결하기 위해 본 논문에서는 Eddystone-EID를 Google을 이용하지 않고 자체적으로 검증하는 방법을 제시한다.

• Journal of the Korean Institute of Telematics and Electronics
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• v.22 no.5
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• pp.87-92
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• 1985

A simple method to derive EID function which is necessary to compensate for the pro-ximity effect in electron-beam lithography is presented. Using optimization techniques, parameters of EID function is derived and well agreed with experimental valuta.

• Clean Technology
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• v.5 no.2
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• pp.79-86
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• 1999

Mutant strain EID was developed by treating Gordona sp. CYKS1 with ethylmethanesulfone, and the desulfurization characteristics of dibenzothiophene(DBT) by mutant EID was investigated. Strain EID desulfurized DBT to 2-hydroxybiphenyl (2-HBP) by 4S pathway. Desulfurization rate of the strain EID was $4.0{\mu}mol{\cdot}L^{-1}{\cdot}h^{-1}$, while that of the wild type CYKS1 was $2.6{\mu}mol{\cdot}L^{-1}{\cdot}h^{-1}$. The effect of glucose concentration supplied as the carbon source on the DBT desulfurization showed that DBT desulfurization rate was enhanced as the glucose concentration increased. Maximum DBT desulfurization rate was $11.1{\mu}mol{\cdot}L^{-1}{\cdot}h^{-1}$ at 2.0 mM DBT concentration. As end-products such as 2-HBP and sulfate concentrations increase, DBT desulfurization activity of the strain EID decreased. When 0.2 mM of 2-HBP was added in the medium, no growth and desulfurization activity was observed. When 0.5 g/L $Na_2SO_4$ was simultaneously supplied with DBT, DBT desulfurization rate was$1.4{\mu}mol{\cdot}L^{-1}{\cdot}h^{-1}$.

• Journal of Korean Neurosurgical Society
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• v.65 no.6
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• pp.790-800
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• 2022

Objective : EID3 (EP300-interacting inhibitor of differentiation) was identified as a novel member of EID family and plays a pivotal role in colorectal cancer development. However, its role in glioma remained elusive. In current study, we identified EID3 as a novel oncogenic molecule in human glioma and is critical for glioma cell survival, proliferation and invasion. Methods : A total of five patients with glioma were recruited in present study and fresh glioma samples were removed from patients. Four weeks old male non-obese diabetic severe combined immune deficiency (NOD/SCID) mice were used as transplant recipient models. The subcutaneous tumor size was calculated and recorded every week with vernier caliper. EID3 and AMP-activated protein kinase α1 (AMPKα1) expression levels were confirmed by real-time polymerase chain reaction and Western blot assays. Colony formation assays were performed to evaluate cell proliferation. Methyl thiazolyl tetrazolium (MTT) assays were performed for cell viability assessment. Trypan blue staining approach was applied for cell death assessment. Cell Apoptosis DNA ELISA Detection Kit was used for apoptosis assessment. Results : EID3 was preferentially expressed in glioma tissues/cells, while undetectable in astrocytes, neuronal cells, or normal brain tissues. EID3 knocking down significantly hindered glioma cell proliferation and invasion, as well as induced reduction of cell viability, apoptosis and cell death. EID3 knocking down also greatly inhibited tumor growth in SCID mice. Knocking down of AMPKα1 could effectively rescue glioma cells from apoptosis and cell death caused by EID3 absence, indicating that AMPKα1 acted as a key downstream regulator of EID3 and mediated suppression effects caused by EID3 knocking down inhibition. These findings were confirmed in glioma cells generated patient-derived xenograft models. AMPKα1 protein levels were affected by MG132 treatment in glioma, which suggested EID3 might down regulate AMPKα1 through protein degradation. Conclusion : Collectively, our study demonstrated that EID3 promoted glioma cell proliferation and survival by inhibiting AMPKα1 expression. Targeting EID3 might represent a promising strategy for treating glioma.

• Molecules and Cells
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• v.24 no.3
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• pp.372-377
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• 2007

The orphan nuclear receptor, SF-1, plays a pivotal role in the development and differentiation of the endocrine and reproductive systems, and also regulates the transcription of a host of genes, including those encoding several steroidogenic enzymes and gonadotropins. We found that a previously unidentified repressor, EID-1, is an SF-1-interacting protein that inhibits the transactivation of SF-1. A transient transfection assay revealed that EID-1 inhibits SF-1, but not LRH-1, $ERR{\gamma}$, or mCAR. Using the yeast two hybrid and GST pull-down assays, we determined that EID-1 interacted strongly with SF-1. In addition, it colocalized with SF-1 in mammalian cells and interacted specifically with the AF-2 domain of SF-1, competing with SRC-1 to inhibit SF-1 transactivation. EID-1 is expressed in the mouse testis, and its expression decreases during testis development. The results of the present study suggest that EID-1 can act as a repressor, regulating the function of SF-1.

• Journal of the Korea Safety Management & Science
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• v.14 no.4
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• pp.239-246
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• 2012

공정제어시스템과 같은 복잡한 시스템을 감시하고 제어하기 위한 정보 디스플레이를 설계하기 위해 두 가지의 세부적인 설계문제를 효과적으로 다루어야 한다. 정보디스플레이에서 표현할 정보의 내용을 파악하고 조직화하는 문제와 그 표현할 정보를 시각적으로 잘 표현하는 문제로 구분이 된다. Ecological Interface Design (EID)는 두 문제를 다루기 위한 이론적 배경지식과 방법을 제공하는 정보디스플레이 설계의 틀이다. EID는 1990년대 초반에 그 개념적 틀이 소개된 이후에 그 유용성이 여러 작업영역과 직무환경에서 입증되어 왔다. 그러나 실제 현장에서 EID의 개념을 활용하는데 있어 큰 어려움으로 지적된 것이 정보의 시각화를 위한 실용적이고 구체적인 원칙과 방법이 부족하다는 점이었다. 또한 EID 개념의 활용에만 집중할 경우 효과적인 정보 디스플레이 설계를 위해 고려되어야 하는 다른 설계 문제들이 쉽게 간과될 가능성도 높다. 이 점은 아직도 EID의 실제적 활용성을 높이는데 큰 약점으로 지적된다. 이 논문에서는 EID의 개요와 장단점을 소개한 후에 이에 기반해서 정보 디스플레이 설계를 종합적으로 다루는 데 도움이 될 수 있는 방법을 소개한다. 특히 이 논문에서는 기능적으로 추상화된 정보의 시각화 및 추상화 관점에서 다른 단계에 있는 정보들간의 목적-수단 관계를 시각화해서 명시화하는 것을 강조한다. 또한 디스플레이 설계 요소에 기반한 설계 프로세스 및 관련 설계 원칙 및 지침의 적절한 활용도 강조한다. 이 논문에서 제안된 방법은 EID의 개념적 틀을 확장하면서 인간 중심적인 정보 디스플레이의 설계하는데 유용한 원칙과 방향성을 정립하는데 도움이 될 것이다.

• Korean Journal of Veterinary Research
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• v.1 no.1
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• pp.36-53
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• 1961

This experiment was conducted on the fowl pox embryo vaccine for the production immunity, and stability, using an attenuated fowl pox virus (Nakano strin). Burnet's window method was applied, that is, 0.1 ml. of seed virus was inoculated on the chorioallantoic membrane of 12-day old chicken embryos, and incubated for 5 to 6 day, and then the result were read. Four kinds of suspensions of different embyo tissue were prepared and tested for the infectivity in chickens. Finally the suspension of chorioallantoic membrane was used as the vaccine throughout the experiment. Results obtained in this experiment are summarized as follows: (1) Of embryo tissue infected with the vaccine virus, chorioallantoic membrane had the highest virus titer of $10^{-5.4}$ $EID_{50}$, and albumen the lowest titer of $10^{-0.7}$ $EID_{50}$. (2) Suspensions of infected whole embryo with or without saline, and de-embryonated whole egg had about the same virus titer of $10^{-4.4}$ $EID_{50}$, whereas the chorioallantoic membrane had $10^{-5.7}$ EID 50 or higher. The virus titer droped one log from $EID_{50}$ when inoculated into chickens. Takes were observed 35.6% of 500 chickens by stick method and 89% of 500 chickens by brush method. (3) The chorioallantoic membrane conferred almost perfect immunity for chickens by 10 days after vaccination. (4) Satisfactory immunity was observed in the chickens when eruption in a single follicle. (5) Eight of 10 vaccinated chickens revealed durable immunity for 307 days following vaccination. (6) The vacuum-dried vaccine maintained its infectiviy for 899 days at $5^{\circ}C$ or below and maintained the vius titer of $10^{-3.6}$ $EID_{50}$. On the other hand, non-desiccated wet vaccine maintained the titer of $10^{-3.0}$ $EID_{50}$ for 50 days of preservation period at $5^{\circ}$. However, in 50% glycerin-saline the infectivtiy of the same wet vaccine dropped to $10^{-1.5}$ $EID_{50}$ (7) The vartation of virus titer of the vaccine before and after desiccation was $10^{-0.5}$ $EID_{50}$ on the average. (8) As suspending media, 0.85 per cent saline and distilled water showed nearly the same effect on the infectivity of the vaccine by retaining the titer $10^{-3.0}$ $EID_{50}$ after 50 days of preservation both at $5^{\circ}C$ and $20^{\circ}C$, while 50 percent cent glycerine-saline dropped the titer to $10^{-2.5}$ EID and $10^{-1.5}$ $EID_{50}$ respectively at $5^{\circ}C$ and $2^{\circ}C$ after the same period.

• Journal of the Ergonomics Society of Korea
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• v.32 no.1
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• pp.1-7
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• 2013

Objective: This study proposes the application of Ecological Interface Design(EID) method that is effective for situation awareness in digitalized environment. Background: While cognitive interface design method such as Information Rich Display(IRD) is simply focused on existing information for user, EID method helps users' resource to be solved to higher ion task such as diagnostic and problem solving. Method: Using EID method based on Work Domain Analysis (WDA), it was analyzed and designed for Steam Generator(SG) Water Level control process in a digitalized Main Control Room of Nuclear Power Plant. Proposed EID example is evaluated through interviews by expert & operator. Results: The result of expert & operator showed that EID display might give an aid for operator's decision. Conclusion: The results can reduce critical accidental damage that occurred due to cognitive load and so critical human error. Application: This study may be impact on situation awareness study for digitalized interface design.

• Journal of the Ergonomics Society of Korea
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• v.25 no.4
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• pp.103-113
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• 2006

The purpose of this study was to evaluate an effect of the new air traffic control display designed by Ecological Interface Design [EID]. The methodology of EID has not been applied to the development of the air traffic control display so far. To design a new air traffic control display by EID, We implemented Work Domain Analysis about the air traffic control domain and made the Work Domain Model that consisted of the five levels of the Abstraction Hierarchy. We extracted the Information Requirement from the completed Work Domain Model and the extracted information requirements from the model were used to design the new air traffic control display. We evaluated an effect of the new air traffic control display designed by EID. Participants for evaluating consisted of 14 active military air traffic controller of the Republic of Korea Air Force. Experiment was designed two factors within subject. Factors manipulated in the experiment included displays type to compare the existing type with the new ecological interface type and included complexity to compare the effect of the high complex situation with the effect of the low complex situation. Response time about questions with relation to air traffic collision situation, accuracy, and subjective work load were measured. The results reveled that EID type's display has a significant effect on response time, accuracy, and subjective work load and verified that EID could be applied to the air traffic control domain that is more complex and dynamic.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2017.11a
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• pp.256-258
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• 2017

사용자 인터페이스를 설계하는 방법의 하나로써 생태적 인터페이스 설계(Ecological Interface Design) 방법이 제안되었고, 다양한 분야에서 이 방법을 활용하여 인터페이스를 설계하고 있다. 그러나 해양분야에서는 EID 사례가 많지 않았다. 따라서 본 연구에서는 생태적 인터페이스 설계의 절차를 살펴보고, 해양분야에서 수행한 몇 가지 EID의 사례를 소개하였다. 마지막으로 선박충돌을 예방하기 위한 EID의 가능성에 대해 제시하였다.