• YAKHAK HOEJI
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• v.41 no.3
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• pp.298-304
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• 1997

Molecular mechanics and conformation search methods were carried oyt to investigate the relationship between conformations and thromboxane synthetase ingibitory activities of om ega-pyridylalkenoic acids. The initial geometries of ${\omega}$-pyridylalkenoic acids and heme part of cytochrome P-450 were obtained from MM+ geometry optimization. The bond lenths and angles were not varied by step during the conformation searching. Stable conformers of some ${\omega}$-pyridylalkenoic acids were obtained by comformational search method. The distances were 8.5~10.8 ${\AA}$- between N atom at 3-position of pyridine ring and C atom at carboxylic group of stable ${\omega}$-pyridylalkenoic acids. The conformations of ${\omega}$-pyridylalkenoic acids and heme part complex were determined by same method. In theses structures, benzene ring and ethylene group in ${\omega}$-pyridylalkenoic acids are making the structure more rigid and increase inhbitory activity. The electron donating groups in C atom shich is connected to pyridine ring also increase activity.

• Journal of applied mathematics & informatics
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• v.31 no.5_6
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• pp.677-693
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• 2013

We construct exponentially fitted interpolation formulas using the values of the ${\omega}$-dependent function $f$ as well as its derivatives up to the $n$th order at a finite number of nodes on a closed interval ${\Omega}$. The function $f$ is of the form, $$f(x)=f_1(x)cos({\omega}x)+f_2(x)sin({\omega}x),x{\in}{\Omega}$$, where $f_1$ and $f_2$ are smooth enough to be approximated by polynomials on ${\Omega}$. Some properties of the formulas are newly found. The properties are numerically investigated and reexamined by producing some figures.

• Proceedings of the KIEE Conference
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• 2015.07a
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• pp.1235-1236
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• 2015

This paper reports hyperelastically stretchable strain gauges based on liquid metal (eutectic gallium-indium;EGaIn) and a platinum-catalyzed silicone elastomer ($Ecoflex^{TM}$). A custom liquidmetal patterning setup was operated to fabricate liquidmetal straingauge on flexible substrate. The printed strain gauges were tested under cyclic uniaxial stretching, twisting, even bending of human finger. By engineering the orientation of solid wires placed over two terminals of t he printed liquid metal resistor, we stably achieved the stretchability of ~800 % which is the highest value reported so far, to the best of our knowledge.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.53 no.5
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• pp.275-284
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• 2004

This paper analyzes the environmental impact and economic effect of introducing the Renewable Portfolio Standard (RPS) into Korean electricity market using the DECADES (Database and Methodologies for Comparative Assessment of Different Energy Source for Electricity Generation) model, a comparative assessment tool developed by IAEA. A bottom up approach is adopted for the evaluation of air pollutant emission and its impact of several RPS scenarios. The environmental damage costs of RPS scenarios are evaluated based on the Extern-E results and Thailand externality study carried by EGA T. The results of this study can be applied in determining or analyzing the national electricity policy and energy policy.

• Radiation Oncology Journal
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• v.7 no.2
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• pp.305-311
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• 1989

Fletcher-Suit colpostat has an internal structure to reduce dose to bladder and rectum. Some programs were developed to calculate dose at any point in water in three dimension around the colpostat containing Cs-137 tube, to find the shielding effect to dose by the internal structure, and to draw isodose curves and iso-shielding effect curves. Computer was an IBM compatible AT with EGA card and language was MS-Basic V6.0, Material, shape and geometry of the strucure, tube and colpostat were considered in algorithm for calculation of dose. Dose rates per unit mg. Ra. eq. in water calculated by a program were stored in auxiliary memory devices and retrieved in another programs. Isodose curves on medial side shrinked. Dose distribution was not symmetric about a transverse axis bisecting the colpostat. Reduction of dose was more excessive on top side than on bottom. Iso-shielding effect curve showed that the shielding effect was higher on top side than on bottom, and that there was shielding effect over almost all area of medial side. Such results were related to both shifted position of tube in the colpostat and asymmetric distribution of active source in the tube. Maximum of shielding effect was $49\%$ on top side and $44\%$ on bottom side. The direction of iso-shielding effect curve was generally radial from the center of active source. In treatment planning using Fletcher-Suit colpostat, the internal structure should be considered to find precise doses to bladder and rectum, etc.

• Journal of KIISE:Databases
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• v.35 no.6
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• pp.459-468
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• 2008

A data stream which is a massive unbounded sequence of data elements continuously generated at a rapid rate. Many recent research activities for emerging applications often need to deal with the data stream. Such applications can be web click monitoring, sensor data processing, network traffic analysis. telephone records and multi-media data. For this. data processing over a data stream are not performed on the stored data but performed the newly updated data with pre-registered queries, and then return a result immediately or periodically. Recently, many studies are focused on dealing with a data stream more than a stored data set. Especially. there are many researches to optimize continuous queries in order to perform them efficiently. This paper proposes a query optimization algorithm to manage continuous query which has multiple join operators(Multi-way join) over data streams. It is called by an Extended Greedy query optimization based on a greedy algorithm. It defines a join cost by a required operation to compute a join and an operation to process a result and then stores all information for computing join cost and join cost in the statistics catalog. To overcome a weak point of greedy algorithm which has poor performance, the algorithm selects the set of operators with a small lay, instead of operator with the smallest cost. The set is influenced the accuracy and execution time of the algorithm and can be controlled adaptively by two user-defined values. Experiment results illustrate the performance of the EGA algorithm in various stream environments.

• Mycobiology
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• v.50 no.2
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• pp.132-141
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• 2022

Amylomyces rouxii is commonly found as amylolytic fungi in tapai fermentation. However, its diversity is rarely reported despite being often used for food production in Southeast Asia. This research aims to analyze the genetic diversity and the distribution pattern of A. rouxii from Ragi tapai in Java Island, Indonesia. We isolated the fungus from samples obtained from Ragi tapai producing centers in Bandung, Sumedang, Muntilan, Blora, Yogyakarta, and Bondowoso. The obtained isolates were molecularly identified based on the ribosomal regions ITS1/ITS2 and D1/D2, then analyzed for phylogenetic tree reconstruction, genetic distance, genetic variation, and haplotype networking. Six isolates showed specific morphological traits of A. rouxii. However, phylogenetic tree reconstruction on the ribosomal genes showed that the isolates were grouped into two different clades related to two species. Clade A included BDG, SMD, and MTL isolates related to A. rouxii, whereas clade B included YOG, BLR, and BDS isolates related to Mucor indicus. The genetic distances between clades for ITS1/ITS2 and D1/D2 were 0.6145 and 0.1556, respectively. In conclusion, we confirmed the genetic diversity of molds from Ragi tapai in Java Island and showed that the isolates are not only related to A. rouxii as reported before.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.5 no.7
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• pp.63-72
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• 1982

The objective of this study is review effective business reorganization measures for tackling financial difficulties for financial managers. The major cause of business failure is incompetent management. Business failure occurs when a company is unable to meet its current obligations, or the net worth of the company is negative : usually the signs of business failure are predictable in advance of its actual accurrence. Discriminant analysis as well as other analytical tools - profile analysis, dichotomous analysis, analysis of likelihood ratios - have been used to predict business failure on the basis of various financial ratios , among those, discriminant analysis has been tell known an excellent technique in predicting business failure. The first question to be raised is whether the business is better off, dead or alive. Assuming the decision is made that the firm should survive, reorganization procedure should be considered. The informal procedures of voluntary settlements used in reorganization are extension : composition and liquidation by voluntary agreement. Unless this settlement is possible by those means, the case goes to the courts for 1ega1 solution. If the court decides on reorganization rather than liquidation, it will appoint a trustee to control the firm for reorganization and to prepare a formal plan of reorganization. the plan must meet the stand of fair, equitable and feasible. In that case, the court will approve the plan.

• Asian-Australasian Journal of Animal Sciences
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• v.25 no.6
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• pp.789-793
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• 2012

Fertilization of the oocyte commences embryogenesis during which maternally inherited mRNAs are degraded and the embryonic genome is activated. Transcription of embryonic mRNA is initiated by embryonic genome activation (EGA). RNA polymerase II (RNA Pol II) is responsible for the synthesis of mRNAs and most small nuclear RNAs, and consists of 12 subunits, the largest of which characteristically harbors a unique C-terminal domain (CTD). Transcriptional activity of RNA Pol II is highly regulated, in particular, by phosphorylation of serine residues in the CTD. Here, we have shown the presence of RNA Pol II CTD phosphoisoforms in porcine oocytes and preimplantation embryos. The distribution pattern as well as phosphorylation dynamics in germinal vesicles and during embryogenesis differed in developmental stages with these isoforms, indicating a role of RNA Pol II CTD phosphorylation at the serine residue in transcriptional activation during both oocyte growth and embryonic genome activation. We additionally examined the effects of the RNA Pol II inhibitor, ${\alpha}$-amanitin, on embryo development. Our results show that inhibition of polymerase, even at very early stages and for a short period of time, dramatically impaired blastocyst formation. These findings collectively suggest that the functionality of maternal RNA Pol II, and consequently, expression of early genes regulated by this enzyme are essential for proper embryo development.

• Journal of KIISE
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• v.43 no.2
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• pp.204-211
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• 2016

In this paper, we propose an automatic melody composition system that can generate a sophisticated melody by adding non-harmony tone in the given chord progression. An overall procedure consists of two steps, which are the rhythm generation and melody generation parts. In the rhythm generation part, we designed new fitness functions for rhythm that can be controlled by a user setting parameters. In the melody generation part, we designed new fitness functions for melody based on harmony theory. We also designed evolutionary operators that are conducted by considering a musical context to improve computational efficiency. In the experiments, we compared four metaheuristics to optimize the rhythm fitness functions: Simple Genetic Algorithm (SGA), Elitism Genetic Algorithm (EGA), Differential Evolution (DE), and Particle Swarm Optimization (PSO). Furthermore, we compared proposed genetic algorithm for melody with the four algorithms for verifying performance. In addition, composition results are introduced and analyzed with respect to musical correctness.