• Asian-Australasian Journal of Animal Sciences
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• v.32 no.10
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• pp.1501-1510
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• 2019

Objective: An experiment was conducted to evaluate genetic diversity of 26 Chinese indigenous goats by 30 microsatellite markers, and then to define conservation priorities to set up the protection programs according to the weight given to within- and between-breed genetic diversity. Methods: Twenty-six representative populations of Chinese indigenous goats, 1,351 total, were sampled from different geographic regions of China. Within-breed genetic diversity and marker polymorphism were estimated calculating the mean number of alleles, observed heterozygosities, expected heterozygosities, fixation index, effective number of alleles and allelic richness. Conservation priorities were analyzed by statistical methods. Results: A relatively high level of genetic diversity was found in twenty-four population; the exceptions were in the Daiyun and Fuqing goat populations. Within-breed kinship coefficient matrices identified seven highly inbred breeds which should be of concern. Of these, six breeds receive a negative contribution to heterozygosity when the method was based on proportional contribution to heterozygosity. Based on Weitzman or Piyasatian and Kinghorn methods, the breeds distant from others i.e. Inner Mongolia Cashmere goat, Chengdu Brown goat and Leizhou goat obtain a high ranking. Evidence from Caballero and Toro and Fabuel et al method prioritized Jining Gray goat, Liaoning Cashmere goat, and Inner Mongolia Cashmere goat, which agree with results from Kinship-based methods. Conclusion: Conservation priorities were determined according to multiple methods. Our results suggest Inner Mongolia Cashmere goat (most methods), Jining Gray goat and Liaoning Cashmere goat (high contribution to heterozygosity and total diversity) should be prioritized based on most methods. Furthermore, Daiyun goat and Shannan White goat also should be prioritized based on consideration of effective population size. However, if one breed can continually survive under changing conditions, the straightforward approach would be to increase its utilization and attraction for production via mining breed germplasm characteristics.

• Journal of Radiation Protection and Research
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• v.30 no.4
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• pp.185-196
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• 2005

Although medical exposure from diagnostic radiology procedures such as conventional x-rays, CT and PET scans is necessary for healthcare purposes, understanding its characteristics and size of the resulting radiation dose to patients is much of worth because medical radiation constitutes the largest artificial source of exposure and the medical exposure is in a trend of fast increasing particularly in the developed society. Annual collective doses and per-caput effective doses from different radiology procedures in Korea were estimated by combining the effective dose estimates per single medical procedure and the health insurance statistics in 2002. Values of the effective dose per single procedure were compiled from different sources including NRPB reports, ICRP 80, MIRDOSE3.1 code and independent computations of the authors. The annual collective dose reaches 27440 man-Sv (diagnostic radiology: 22880 man-Sv, nuclear medicine: 4560 man-Sv) which is reduced to the annual per-caput effective dose of 0.58 mSv by dividing by the national population of 47.7 millions. The collective dose is far larger than that of occupational exposures, in the country operated 16 nuclear power plants in 2002, which is no more than 70 man-Sv in the same year. It is particularly noted that the collective dose due to CT scans amounts 9960 man-Sv. These results implies that the national policy for radiation protection should pay much more attention to optimization of patient doses in medicine.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.11
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• pp.1691-1699
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• 2018

Objective: In Korea, there are three main cattle breeds, which are distinguished by coat color: Brown Hanwoo (BH), Brindle Hanwoo (BRH), and Jeju Black (JB). In this study, we sought to compare the genetic diversity and divergence among there Korean cattle breeds using a BovineHD chip genotyping array. Methods: Sample data were collected from 168 cattle in three populations of BH (48 cattle), BRH (96 cattle), and JB (24 cattle). The single-nucleotide polymorphism (SNP) genotyping was performed using the Illumina BovineHD SNP 777K Bead chip. Results: Heterozygosity, used as a measure of within-breed genetic diversity, was higher in BH (0.293) and BRH (0.296) than in JB (0.266). Linkage disequilibrium decay was more rapid in BH and BRH than in JB, reaching an average $r^2$ value of 0.2 before 26 kb in BH and BRH, whereas the corresponding value was reached before 32 kb in JB. Intra-population, interpopulation, and Fst analyses were used to identify candidate signatures of positive selection in the genome of a domestic Korean cattle population and 48, 11, and 11 loci were detected in the genomic region of the BRH breed, respectively. A Neighbor-Joining phylogenetic tree showed two main groups: a group comprising BH and BRH on one side and a group containing JB on the other. The runs of homozygosity analysis between Korean breeds indicated that the BRH and JB breeds have high inbreeding within breeds compared with BH. An analysis of differentiation based on a high-density SNP chip showed differences between Korean cattle breeds and the closeness of breeds corresponding to the geographic regions where they are evolving. Conclusion: Our results indicate that although the Korean cattle breeds have common features, they also show reliable breed diversity.

• Korean Journal of Ichthyology
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• v.27 no.1
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• pp.10-15
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• 2015

Giant grouper (Epinephelus lanceolatus) is a endangered species considered as a vulnerable grade-organism in the International Union for Conservation of Nature (IUCN) red list. As a fundamental baseline study for establishing a giant grouper broodstock management system, the efficiency for parentage analysis was evaluated by using microsatellite makers previously available in this species. The eight microsatellites generated a total 52 alleles from 32 individuals, the mean expected heterozygosity was 0.663, and mean inbreeding coefficient was 0.011, consequently suggesting that the present broodstock has retained the high level of genetic diversity. However, our analysis also recommended the collection of more broodfish for more stable brood line, since the estimated value of the effective population size was proven to be 35. The average probability of identity was $6.85{\times}10^{-11}$. NE-2P and NE-PP of paternity non-exclusion probabilities were 0.00835 and 0.00027, respectively. As the result of principle coordinate analysis, the genotype of broodstock was not overlapped, suggesting that the management system of giant grouper based on eight selected microsatellite markers might be effective, although further validation with extended number of broodfish might also be needed in future. Data of present study could be a useful basis to avoid the unwanted selection of broodfish that possess close genetic relationship with current broodstock, and consequently to establish effective broodstock management system allowing the production of progeny with high genetic diversity.

• The Journal of Korean Society for School & Community Health Education
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• v.8 no.1
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• pp.1-11
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• 2007

Objectives: School must provide the proper sex education to students, thereby, the students for have right standards of sexuality and preventing from sexual crimes. This study conducted to identify the effectiveness and students' satisfaction level on Sex education program for middle school students prepared by the Ministry of Education and Human Resources. Methods: The sample size of the study was 644 students(458 female students and 186 male students) in middle school. A self reporting type of questionnaire survey was conducted from May 2 through May 27, 2005. Collected data were processed using SPSSwin 12.0; The data were analysed through t-test, stepwise multiple regression analysis. Results: Lectures and audiovisual materials were mostly used for sex education for students. Many students were satisfied with the program of physical and sexual organ development, pregnancy, contraceptive methods and sexual abuse. Many students wanted to study more on courtship, love, and marriage. The programs which the students did not understand well were sexually transmitted diseases, pregnancy and mass media and sex. Forty six percentage of the students reported that they were satisfied with the education program. Thirty three percentage of the students said that they were not satisfied with the program. The students who had earlier menstruation experience and the students whose academic achievement were higher were more satisfied with sex education program (P<.05). The students who were satisfied with the sex education CD prepared by the ministry of education were more satisfied with sex education program. (P<.001). When the CDs were appropriately used, the students were more satisfied with the education program (P<.05). The sound and pictures in the CD did not much affect the students. Audiovisual programs were more effective than lectures.

• Biomedical Science Letters
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• v.24 no.2
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• pp.138-142
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• 2018

The incidence of tuberculosis (TB) in the Republic of Korea remains high when compared to the incidence in other Organization for Economic Cooperation and Development (OECD) countries. The prompt diagnosis and effective treatment of latent TB infection (LTBI) are very important in terms of controlling the burden of TB. The tuberculin skin test (TST) has long been the "gold standard" assay for the diagnosis of LTBI. However, it can show false positive results due to Bacille Calmette-$Gu{\acute{e}}rin$ (BCG) vaccination and infection with many environmental nontuberculous mycobacteria (NTM). The interferon gamma release assay (IGRA) using Mycobacterium tuberculosis (MTB)-specific antigens, was developed for the detection of LTBI. The QuantiFERON-TB Gold In-Tube assay is one of the most commonly used forms of the IGRA. In order to compare the diagnostic efficacy of the TST and IGRA in relation to LTBI among BCG-vaccinated healthy donors, whole blood samples were collected from 51 participants, and the results of the TST and IGRA were compared. Of the 51 cases, 18 cases (35.3%) were positive and 33 cases (64.7%) were negative when using the TST, while four cases (7.8%) were positive and 47 cases (92.2%) negative when using the IGRA. There was no correlation between the size of the induration in the TST and the $IFN-{\gamma}$ protein level. In conclusion, the TST showed higher cross-reactivity among the BCG-vaccinated healthy participants, therefore, the IGRA might be the most suitable assay for the rapid screening of LTBI in BCG-vaccinated healthy population, or for TB contact investigation.

• Journal of Environmental Impact Assessment
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• v.19 no.3
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• pp.347-356
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• 2010

Forests are being seriously fragmented as a result of land development. Land development with disregard to its subsequent environmental impacts is a primary threat to biodiversity by incurring massive habitat losses and changes in structure and composition of forests. The purpose of this study was to develop the impact assessment model for quantitative distance or degree of disturbance by land developments. This study conducted a survey about structure and composition of forest species to determine degree of impact from land development. The edge effect of forest fragmentation on the number of bird species, population size, and bird diversity was obvious. In particular, the bird diversity sharply declines around the forest edge where intensive land development projects take place. To assess the disturbance of forest species, the factors selected were the bird diversity and the rate of edge species. The impact assessment model about bird diversity was explained by type of forest fragmentation and type of vegetation ($R^2$=0.23, p<0.005). The other model about edge species explained by a distance, type of forest fragmentation, type of vegetation, and width of road ($R^2$=0.34, p<0.001). In order to test the applicability of the model developed in this study, the models was applied to the Samsong housing development in Goyang-si, Gyunggi-do. The impacts of land development on the bird species were reasonably quantified to suggest effective mitigation measure. The impact assessment model developed in this study is useful to assess the magnitude of disturbance of bird species. Particularly, the model could be applied to the current Environmental Impact Assessment practices to predict and quantify the impacts of land developments projects on forest bird species.

• Journal of the Korean Institute of Intelligent Systems
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• v.7 no.2
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• pp.16-24
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• 1997

This paper proposes a modified GA whose individuals have their own ages. Thus, a chromosome will die only when the age becomes zero, as a result, the population size of this method increases according to the generations. This helps a GA to preserve the good characteristics of a few chromosomes during several generations if the ages are evaluated with fitness values. As a result, the performance of the method is better than that of existing ones. A multi-modal function optimization problem is employed to simulate the performance of this method. To show the effective:~esso f ageing paradigm, three ageing evaluation methods are introduced. A paper whose itlea is similar to that of ours have been published in a conference. We also experimented a method that showed the best performance in the paper. Original simple GA was also experimented and the performance is compared with others. However, the perforniance of the previous method shows worse than that of our methods in some aspects because the previous method didn't take the fitness value into account in the selection process.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.12 no.6
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• pp.582-590
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• 2019

As Korea's low fertility and aging progress, Korea is facing a social change such as an increase of one generation by entering an aging society that has raised 14% of the population. An effective way to prevent a gas fire accident caused by an increase in one generation in an aging society is to install a control valve to forcibly shut off the gas after a set time. In this study, we developed a valve that can be opened and closed by rotating the valve left and right by transmitting power to the worm gear and the helical gear by using a motor by pressing the switch. It is easy to assemble and inspect by developing a dedicated valve that is easy to attach and detach. It was developed to enhance competitiveness by reducing cost by reducing the number of parts and product size. In addition, through endurance test, it was developed to be used for more than 9 years by repeating ON / OFF once every 12 seconds so that it can operate stably for 10,000 times for 34 hours. The instrument and PCB were designed using solid works and Altium Designer tools. Firmware development was developed in IAR Embedded Workbench environment.

• Journal of the Korean Society of Visualization
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• v.17 no.3
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• pp.24-31
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• 2019

Recently, an air-lift bio-reactor operated by micro bubbles has been utilized to product hydrogen fuel. To enhance the performance, characteristics of hydrodynamics inside the bio-reactor were analyzed using a numerical simulation for two-phase flow. An Eulerian model was employed for both of liquid and gas phases. The standard k-ε model was used for turbulence induced by micro bubbles. A Population Balance Model was employed to consider size distribution of bubbles. A hollow cylinder was introduced at the center of the reactor to reduce a dead area which disturbs circulation of CO bubbles. An appropriate diameter of the draft tube and hollow cylinder were optimized for better performance of the bio-reactor. The optimum model could be obtained when the cross-sectional area ratio of the hollow cylinder to the reactor, and the width ratio of the riser to the downcomer approached 0.4 and 3.5, respectively. Consequently, it is expected that the optimum model could enhance the performance of the bio-reactor with the homogeneous distribution and higher density of CO, and more effective mixing.