• The Korean Journal of Zoology
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• v.34 no.4
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• pp.469-478
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• 1991

The CALLA on the surface of leukemic cell lines, recognized by our monoclonal antibody. KP-22(IgG1, K) was one of cell surface glycoproteins having moi. wt. of approximately 100,000 dalton, and could be shed in spent medium or endocytosed when binding the cognate antidoby, KP-22. In the presence of cognate antibodies, 60% of CALLAS recogniEed by KP-22 MAs were modulated and cleared from the cell surface during 24 hrs, and approximaetely 35% of them was endocytosed and 25%, was shed in spent medium. The reappearance of the membrane CALLA after modulation by the KP-22 required at least 6 hours and supposed to be newly synthesized molecules.

• Development and Reproduction
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• v.15 no.4
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• pp.273-279
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• 2011

Epigenetic regulation is a phenomenon that changes the gene function without changing the underlying DNA sequences. Epigenetic status of chromosome is regulated by mechanisms such as histone modification, DNA modification, and RNAi silencing. In this review, we focused on histone methylation for epigenetic regulation in ES cells. Two antagonizing multiprotein complexes regulate methylation of histones to guide expression of genes in ES cells. The Polycomb repressive complex 2 (PRC2), including EED, EZH2, and SUZ12 as core factors, contributes to gene repression by increasing trimethylation of H3K27 (H3K27me3). In contrast, the Trithorax group (TrxG) complex including MLL is related to gene activation by making H3K4me3. PRC2 and TrxG accompany a variety of accessory proteins. Most prominent feature of epigenetic regulation in ES cells is a bivalent state in which H3K27me3 and H3K4me3 appear simultaneously. Concerted regulation of PRC2, TrxG complex, and H3K4- or H3K27-specific demethylases activate expression of pluripotency-related genes and suppress development-related genes in ES cells. Modified balance of the regulators also enables ES cells to efficiently differentiate to a variety of cells upon differentiating signals. More detailed insights on the epigenetic regulators and their action will lead us to better understanding and use of ES cells for future application.

• Journal of Chest Surgery
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• v.29 no.7
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• pp.798-801
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• 1996

Solitary fibrous tumors of the pleura are rare, slow-growing benign neoplasm, originating from submesothelial Hbroblasts. Approximately 80% of solitary fibrous tumors of the pleura originate in . the visceral pleura and 20% in the parietal pleura. Many of these tumors are pedunculated, attached to the visceral pleura via a well-vasculariEed stalk, and in size from 1 to 36cm with a mean of 6cm. This case report is of a 48 year old woman who presented with dyspnea and right flank pain. Preoperative chest x-ray showed increased hazy density at right lower lung field, and CT scan showed huge heterogeneous mass which was located in right mid and lower thorax. She underwent surgical resec- tion and a lOX15X loom(2200gm weigh) sized large mass was excised. Final histologic diagnosis was solitary fibrous tumor of the plara. The patient was discharged without any complications postoperately.

• Journal of the Korean Society of Food Culture
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• v.20 no.2
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• pp.273-282
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• 2005

The purpose of this study was to nut a survey on the seasonal menu and consumer's acceptance test of free meals for the elderly facility in Sungnam Region. The elderly meals of the free lunch meal service were mainly composed of staple food, hot soup, and three kinds of side dishes. Questionare for accentance test was developed based on the seasonal menu including 13 kinds of cooked rices, 43 kinds of soups and 94 kinds of side dishes. The test was run for 104 elderly living and receving the service in the area. Average age of the subjects was 75.9 and 43% was male 57% was female. The 81% and 88% of the subject answered 'yes' on the intake of breakfast and dinner respectively representing high percentages of regular meal habits of the elderly. The cooked rice with black beans had significantly the highest acceptance score among the rice group and soups prepared with chunggukjang and cabbage had higher accentance scores(P<0.05). In the side dish groups, broiled eed, croakers, and various kinds of namuls had relatively higher scores than the others with significant difference at P<0.05.

• Korean Journal of Microbiology
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• v.35 no.2
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• pp.153-157
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• 1999

The effececl of levanoclaose produced by levanase Croni Pseuc/olol~~o!!n.s sp. K-52 on pnnciple inlesimal microflorawas investigated. The reaction product, levanoctaose, was used as a carbon source for various intestinalmicroflora. Especially. Bijidobacteriulolr~ adolescentis and Lnctohaciilrrs ocidophilus grew effectively in vitroexpeiiments, whereas Clostridiunz per.frilol~gerzs, Bactetvid,~ngilis, Eschericlzin. coli, and Stnplzylococcus nureirsdid not. Therefore, levanoctdose seemed to proinole selectively the growth ol" B. ndo1escenti.r and L. acidol~hi-/us. In Lhe in viva experiments, the effects of levanoctaose on inlestinal nucroflora were examined on heirgrowth. $\beta$-fri~ctosidase acliviiy. and butyrate concenuation in rats. Appuently, die number of fecal Bifidobacteria.the amount of bulyrate, and $\beta$-hctosidase activity were increased, whereas total aerobes 'and pH werereduced in rals Eed leviu~octaose diets, cornpxed with hose of the control diets. We concluded hat those effecismay be beneficial in improving gastrointestinal health.astrointestinal health.

• The Korean Journal of Zoology
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• v.32 no.4
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• pp.329-338
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• 1989

Present study examined the effect of intermittent versus continuous infusion of progesterone(P) on LHRH release in uiuo from the mediobasal hvpothalamus of ovariectomiEed, estradiol-primed adult rats bearing push-pull cannulae. Three experimental groups were studied: 1) control (perfusion medium only),2) intermittent perfusion of P (10-min on,20-min off, and 3) continuous perfusion of p. p (10 ng/mll was directly infused into the MBH following a 3 hr basal collection. Perfusates were collected at 10 min intents린s on ice and LHRH release was measured by LHRH radioimmunoassav. Cycle detector analysis revealed that the spontaneous HRH output in the control group was pulsatile over a 7 hr push-pull perfusion period. The mean basal LHRH release, pulse amplitude and pl서se period were 0.68 $\pm$ 0.03 ps110 min, 1.15 $\pm$0.08 pg and 60 $\pm$ 9 min, respectivelv. Intermi구eat perfusion of P clearly stimulated the mean LHRH release (pre-P vs post-P: 1.14 $\pm$ 0.18 vs 1.99 $\pm$ 0.53 pg) without changes in LHRH pulse frequency. In contrast to intermittent infusion of p, continuous administration of P faithed to modify LHRH release, since the mean LHRH release and pulse amplitude between pre-P and post-P perfusion urere similar. The in vitro study clearly showed that intermittent, but not continuous administration of P is effective in stimulating LHRH release. Therefore, it appears that rhythmic secretion of P mal be the erective signal for activating the neural LHRH apparatus.

• Journal of the Korean Solar Energy Society
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• v.25 no.4
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• pp.69-76
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• 2005

The performance of water-to-water heat pump system coupled with the ground source vertical heat exchanger is presented in this paper. The CAP program of Florida Heat Pump Co. is used to predict the heat pump performances while the EED program calculates the borehole fluid temperature. It is shown that COPH increases with decreasing the temperature of output water for the operation of heating mode and COPR increases with increasing temperature of output water for the operation of cooling mode. The value of specific heat extraction rate must be moderate to insure the reasonable installation cost of borehole system. With $1^{\circ}C$decrease of $T_{wo}$ the average COPH increase is estimated as about $0.06/^{\circ}C$(for $T_{wo}\;=\;45{\sim}60^{\circ}C$ range) while with $1^{\circ}C$ increase of $T_{wo}$ the estimation of COPR increase is about $0.13/^{\circ}C$(for $T_{wo}\;= \;5{\sim}11^{\circ}C$ range) at the specific heat extraction rate of 30W/m.

• Plant Resources
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• v.8 no.3
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• pp.281-285
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• 2005

In order to select suitable fertilizer level and sowing rate of Dangyo $^{#8}$(hybrid) rapeseed at the southern area of Korea, two varieties of Naehanyuchae (Normal) and Dangyo $^{#8}$(hybrid) rapeseed currently grown for oil production by two fertilizer level with 10-8-8 kg/10a and 15-8-8 kg/10a and three sowing rate with 500 g/10a, 1,000g/10a and 1,500g/10a with relatively high yield was grown at the same condition yield and yield components were observed. Dangyo $^{#8}$(hybrid) rapeseed was superior to oil-eed rapeseed for yield at the 15-8-8 kg/10a of fertilizer and 1,500 g/10a of sowing rate. Fertilizer level, $N-P_{2}O_5-K_{2}O$ = 15-8-8 kg/10a and sowing rate, 1,500 g/10a showed somewhat higher value in two varieties of Naehanyuchae(Normal) and Dangyo $^{#8}$(hybrid).

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.2
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• pp.1-11
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• 2016

Objective : The purpose of this study is to analyze research trends on the cost-effectiveness in acupuncture for patients with allergic rhinitis. Methods : The literature and research in allergic rhinitis was searched in electronic databases, such as National Health Service Economic Evaluation Database(NHS EED) and the Cochrane Database of Systematic Reviews(CDSR). The general characteristics and the results of each economic analysis such as incremental cost-effectiveness ratios(ICERs) were extracted. Results : In total, thirty seven studies were searched, and two studies were analyzed. They were cost-utility analysis(CUA)s that measured quality-adjusted life years(QALYs). One study showed that the ICER was €22,798 per QALY and was robust in sensitivity analysis. Another showed that the ICER was between €31,241 and €118,889 from society's perspective and between €20,807 and €74,585 from a third-party payer's perspective. Conclusions : Any generalization of these results needs to be made with caution given the specific effects of acupuncture and the difference of cost data in the various countries. Further studies are needed on this topic in order to demonstrate the cost-effectiveness clearly.

• Parasites, Hosts and Diseases
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• v.58 no.2
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• pp.129-134
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• 2020

In most developing countries, Dientamoeba fragilis infection is an obscure protozoan infection. We aimed to determine a frequency and clinical importance of D. fragilis infection in Taif, Saudi Arabia. A 1-year case control study included patients with gastrointestinal (cases, n=114) or non-gastrointestinal symptoms (controls, n=90). The fecal samples were examined with the classical parasitological methods for intestinal protozoa, and by real time PCR for D. fragilis. The infection by D. fragilis was detected in 5.8% by PCR and in 4.4% patients by microscopy. The infection was identified more in control group (n=9) than in cases (n=3); a sole infection in 11 patients and mixed with Giardia in 1 patient. The other enteric parasites detected were Blastocystis sp. (8.3%), Giardia sp. (5.3%), Cryptosporidium sp. (2.9%), Entamoeba histolytica (1.4%), Entamoeba coli (0.9%) and Hymenolepis nana (0.4%). Our results tend to reinforce the need to increase awareness of D. fragilis infection in Saudi Arabia.